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Source: Journal of the Neurological Sciences

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Total 856 results found since Jan 2013.

Mechanical thrombectomy in acute ischemic stroke patients with left ventricular assist device
As the number of patients with left ventricular assist device (LVAD) implantation has been increasing, treatment of LVAD-related ischemic stroke is becoming a critical issue. We sought to clarify the features of mechanical thrombectomy in LVAD-related stroke with large vessel occlusion.
Source: Journal of the Neurological Sciences - September 16, 2020 Category: Neurology Authors: Takaya Kitano, Manabu Sakaguchi, Hiroshi Yamagami, Tatsuya Ishikawa, Hatsue Ishibashi-Ueda, Kanta Tanaka, Shuhei Okazaki, Tsutomu Sasaki, Yoshinori Kadono, Masatoshi Takagaki, Takeo Nishida, Hajime Nakamura, Masanobu Yanase, Norihide Fukushima, Masayuki S Source Type: research

Blood pressure management after mechanical thrombectomy in stroke patients
Endovascular treatment of acute ischemic stroke (AIS) and mechanical thrombectomy (MT) is proven as a safe and effective novel treatment for emergent large vessel occlusion in the anterior cerebral circulation. However, there are still many unanswered questions on peri and post-procedural management including blood pressure (BP) control. The current guidelines recommend maintaining BP
Source: Journal of the Neurological Sciences - September 12, 2020 Category: Neurology Authors: Mostafa Jafari, Aaron Desai, Rahul Damani Tags: Review Article Source Type: research

Prevalence and predictors of post-stroke epilepsy among Ghanaian stroke survivors
Post-stroke epilepsy (PSE) is associated with poorer quality of life, higher mortality, and greater health expenditures. We are unaware of any published reports on the frequency of and factors associated with PSE in Africa.
Source: Journal of the Neurological Sciences - September 10, 2020 Category: Neurology Authors: Fred Stephen Sarfo, John Akassi, Vida Obese, Sheila Adamu, Manolo Agbenorku, Bruce Ovbiagele Source Type: research

Towards evidence-based policies to strengthen acute stroke care in low-middle-income countries
Stroke is a major public health issue in many low- and middle-income countries (LMICs). Despite the emergence of new effective interventions for acute stroke care, uptake remains slow and largely inaccessible to patients in LMICs, where health systems response has been inadequate. In this paper, we propose a policy framework to optimise access to acute stroke care in LMICs. We draw on evidence from relevant primary studies, such as availability of evidence-based acute stroke care interventions, barriers to uptake of interventions for stroke care and insights on stroke mortality and morbidity burden in LMICs.
Source: Journal of the Neurological Sciences - September 2, 2020 Category: Neurology Authors: Leonard Baatiema, Seye Abimbola, Ama de-Graft Aikins, Albertino Damasceno, Andre Pascal Kengne, Fred S. Sarfo, Augustina Charway Felli, Shawn Somerset Tags: Editorial Source Type: research

Characterisation of recent trends in cardiovascular risk factors in young and middle-aged patients with ischaemic stroke and/or transient ischaemic attack
Strokes in the young and middle-aged are associated with a disproportionately large economic and social impact in addition to their clinical effects. Standard Modifiable Cardiovascular Risk Factors (SMuRFs; hypercholesterolaemia, hypertension, diabetes mellitus and smoking) are key drivers of cardiovascular disease including strokes, however recent temporal trends in the younger stroke population have not been well characterised. We aimed to evaluate recent trends of SMuRFs in a cohort of younger patients with ischaemic stroke.
Source: Journal of the Neurological Sciences - September 1, 2020 Category: Neurology Authors: Aditya Bhat, Gary C.H. Gan, David Makarious, Elizabeth Tan, Henry H.L. Chen, Nigel Wolfe, Lina Lee, Camelia Burdusel, Maria Carmo P. Nunes, Clara K. Chow, Timothy C. Tan Source Type: research

Differentiation of seizure from stroke using advanced imaging in the acute period
Imaging modalities such as dynamic computed tomography (CT) studies of the brain have aided in clinical management of stroke patients through identification of tissue at risk and tissue infarcted. Such a capability provides the opportunity to intervene in stroke patients previously deemed unfit for thrombectomy, [1] while allowing software engineers to develop modeling tools stratifying the risk and benefit of intervention [2]. One unexpected consequence of these advances is the ability to recognize the neurophysiologic changes associated with stroke mimics such as seizure.
Source: Journal of the Neurological Sciences - August 31, 2020 Category: Neurology Authors: Merritt W. Brown Tags: Letter to the Editor Source Type: research

The potential impact of enhanced hygienic measures during the COVID-19 outbreak on hospital-acquired infections: A pragmatic study in neurological units
This study aimed to investigate if enhanced hygienic measures, including the systematic use of personal protective equipment (PPE), determined a decrease in HAI during the recent COVID-19 outbreak in “COVID-free” neurological units.
Source: Journal of the Neurological Sciences - August 28, 2020 Category: Neurology Authors: Emanuele Cerulli Irelli, Biagio Orlando, Enrico Cocchi, Alessandra Morano, Francesco Fattapposta, Vittorio Di Piero, Danilo Toni, Maria R. Ciardi, Anna T. Giallonardo, Giovanni Fabbrini, Alfredo Berardelli, Carlo Di Bonaventura Tags: Clinical short communication Source Type: research

Stroke as a delayed manifestation of multi-organ thromboembolic disease in COVID-19 infection
Here, we report a patient with COVID-19 with delayed onset multi-vessel cerebral infarcts and systemic pro-thrombotic state and coagulopathy manifesting as acute limb ischemia and pulmonary embolism to highlight the importance of vigilant monitoring for neurologic impairment and coagulopathy in patients with severe cases of COVID-19 infection. In December 2019, a cluster of pneumonia cases emerged in Wuhan, Hubei Province; later identified as a novel severe acute respiratory syndrome coronavirus (SARS-CoV-2), also known as coronavirus disease 2019 (COVID-19).
Source: Journal of the Neurological Sciences - July 28, 2020 Category: Neurology Authors: Jay L. Liu, Ayaz M. Khawaja, Ariel Q. Majjhoo Tags: Letter to the Editor Source Type: research

Risk factors, etiology, and outcome of ischemic stroke in young adults: A Japanese multicenter prospective study
This study aimed to evaluate the risk factors, etiology, and outcomes of ischemic stroke (IS) in Japanese young adults.
Source: Journal of the Neurological Sciences - July 28, 2020 Category: Neurology Authors: Yu Kono, Yuka Terasawa, Kenichiro Sakai, Yasuyuki Iguchi, Yasuhiro Nishiyama, Chikako Nito, Satoshi Suda, Kazumi Kimura, Takao Kanzawa, Ichiro Imafuku, Takahiro Nakayama, Masayuki Ueda, Takeshi Iwanaga, Tomoyuki Kono, Kazuo Yamashiro, Ryota Tanaka, Seiji Source Type: research

Elevated fasting blood glucose is predictive of the severity and poor outcome in nondiabetic patients with cerebral venous thrombosis
Although elevated fasting blood glucose (FBG) at admission is associated with poor outcome in patients with ischemic and hemorrhagic stroke, it has not been investigated in patients with cerebral venous thrombosis (CVT). We aimed to determine the correlation between elevated FBG and severity and outcome among CVT patients.
Source: Journal of the Neurological Sciences - July 15, 2020 Category: Neurology Authors: Yating Wu, Lixin Zhou, Ming Yao, Yicheng Zhu, Jun Ni, Liying Cui, Bin Peng Source Type: research

Hemorrhagic stroke in hispanics with severe SARS-CoV2 infection
An increasing body of evidence suggests that the coronavirus disease 2019 (SARS-CoV2) may be associated with cerebrovascular disease, although most cases have been ischemic strokes related to occlusion of major intracranial vessels [1 –3]. Intracranial hemorrhages in the setting of SARS-CoV2 infection are exceedingly rare. To the best of our knowledge, only two cases has been reported in detail, one with a massive parenchymal brain hemorrhage and the other with an aneurysmal subarachnoid hemorrhage [4,5].
Source: Journal of the Neurological Sciences - July 14, 2020 Category: Neurology Authors: P.R. Castillo, O.H. Del Brutto, H. Mautong, M. Garc ía, M. Tovar, E.H. Middlebrooks, E. Bologna Tags: Letter to the Editor Source Type: research

Local anesthesia vs general anesthesia during endovascular therapy for acute posterior circulation stroke
The optimal anesthetic approach during endovascular therapy (EVT) in acute stroke patients remains an area of uncertainty. We investigated the impact of different anesthetic approaches on the outcome of posterior circulation stroke (PCS) patients undergoing EVT.
Source: Journal of the Neurological Sciences - July 14, 2020 Category: Neurology Authors: Longfei Wu, Ashutosh P. Jadhav, Jian Chen, Chenghe Sun, Kangxiang Ji, Weili Li, Wenbo Zhao, Chuanhui Li, Chuanjie Wu, Di Wu, Xunming Ji Source Type: research

COVID-19 AND STROKE: Experience in a GHANAIAN healthcare system
Background:The novel coronavirus disease 19 (COVID-19) causes multi-system disease including possibly heightened stroke risk. Data from high-income countries (HIC) suggest disruptions to care delivery with reduced stroke admissions and administration of acute stroke reperfusion therapies. We are unaware of any published data on the impact of the COVID-19 pandemic on stroke admissions and outcomes in sub-Saharan Africa.Purpose: To compare rates of stroke admissions and case fatality between corresponding periods in 2020 and 2019, within a hospital system in Ghana, to assess the potential impact of the COVID-19 pandemic.
Source: Journal of the Neurological Sciences - July 14, 2020 Category: Neurology Authors: Fred S. Sarfo, Naa Oboshie Mensah, Francis Agyapong Opoku, Nathaniel Adusei-Mensah, Michael Ampofo, Bruce Ovbiagele Source Type: research

False-positive anti-neuronal nuclear antibody type 1 in a patient with RFC1 repeat expansion: Preventing “phenotype creep” in autoimmune neurology
A 61-year-old man was referred for evaluation of anti-neuronal nuclear antibody type 1 (ANNA-1, or “anti-Hu”)-associated sensory neuronopathy. Past medical history was significant for a right subcortical stroke involving the subthalamic nucleus three years prior. Family history was unremarkable. He reported insidiously progressive gait imbalance over 15 years, and worsening balance with hea d movement. He also noted mild dysarthria and left hemiparesis following his stroke. He had undergone plasma exchange one year prior to referral without clinical improvement.
Source: Journal of the Neurological Sciences - July 7, 2020 Category: Neurology Authors: Adrian Budhram, John R. Mills, Kamal Shouman, P. James B. Dyck, Anhar Hassan, Nicholas L. Zalewski Tags: Letter to the Editor Source Type: research

Good recanalization is associated with long term favorable outcomes in acute stroke patients with large vessel occlusion treated with endovascular therapy
The long-term outcome in acute stroke patients with large vessel occlusion (LVO) treated with endovascular therapy (EVT) are unclear. We investigated functional outcomes one year after EVT in acute stroke patients with LVO.
Source: Journal of the Neurological Sciences - July 1, 2020 Category: Neurology Authors: Masafumi Arakawa, Kentaro Suzuki, Akihito Kutsuna, Takehiro Katano, Takuya Kanamaru, Junya Aoki, Yuki Sakamoto, Satoshi Suda, Kazumi Kimura Source Type: research