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Source: Journal of the Neurological Sciences
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Total 856 results found since Jan 2013.
Investigating the neuroanatomy underlying proprioception using a stroke model
Neuroanatomical investigations have associated cortical areas, beyond Primary Somatosensory Cortex (S1), with impaired proprioception. Cortical regions have included temporoparietal (TP) regions (supramarginal gyrus, superior temporal gyrus, Heschl's gyrus) and insula. Previous approaches have struggled to account for concurrent damage across multiple brain regions. Here, we used a targeted lesion analysis approach to examine the impact of specific combinations of cortical and sub-cortical lesions and quantified the prevalence of proprioceptive impairments when different regions are damaged or spared.
Source: Journal of the Neurological Sciences - October 11, 2021 Category: Neurology Authors: Matthew J. Chilvers, Rachel L. Hawe, Stephen H. Scott, Sean P. Dukelow Source Type: research
Psychiatric sequelae of stroke affecting the non-dominant cerebral hemisphere
There are a plethora of cognitive sequelae in addition to neglect and extinction that arise with unilateral right hemispheric stroke (RHS). Cognitive deficits following non-dominant (right) hemisphere stroke are common with unilateral neglect and extinction being the most recognized examples. The severity of RHS is usually underestimated by the National Institutes of Health Stroke Scale (NIHSS), which in terms of lateralized right hemisphere cognitive deficits, tests only for visual inattention/extinction.
Source: Journal of the Neurological Sciences - September 26, 2021 Category: Neurology Authors: Cynthia Guo, Christoph Stretz, Jordan Roderick Anderson, Nada El-Husseini, Brian Mac Grory, Blake Werner, Stephanie Yarnell Tags: Review Article Source Type: research
Color-coded multiphase computed tomography angiography may predict outcome in anterior circulation acute ischemic stroke
To evaluate whether arterial and venous color-coded mCTA score may predict clinical outcome in anterior circulation acute ischemic stroke.
Source: Journal of the Neurological Sciences - September 15, 2021 Category: Neurology Authors: Fabio Pilato, Tommaso Verdolotti, Rosalinda Calandrelli, Iacopo Valente, Edoardo Monelli, Simone Cottonaro, Fioravante Capone, Francesco Motolese, Gianmarco Iaccarino, Sergio Soeren Rossi, Cesare Colosimo, Vincenzo Di Lazzaro Source Type: research
Impact of systemic inflammatory response syndrome on acute ischemic stroke patients treated with mechanical thrombectomy
Systemic inflammatory response syndrome (SIRS) has been associated with poor outcomes after acute ischemic stroke (AIS). The primary goal of this study was to determine whether SIRS status on admission correlated with functional outcomes in AIS treated with mechanical thrombectomy (MT).
Source: Journal of the Neurological Sciences - September 15, 2021 Category: Neurology Authors: Mostafa Jafari, Kalman Katlowitz, Carlos De la Garza, Alexander Sellers, Shawn Moore, Hayden Hall, Aaron Desai, Vikramjeet Singh, Rahul Damani Source Type: research
The level of urbanization influences acute ischemic stroke care: A nationwide ecological study from Germany
Regional differences in acute ischemic stroke (AIS) care are still reported for Germany but not fully understood. We aimed to analyze the impact of the level of urbanization on the application of proved treatment procedures and the incidence of hospitalized AIS cases in Germany.
Source: Journal of the Neurological Sciences - September 12, 2021 Category: Neurology Authors: Daniel Richter, Jens Eyding, Ralph Weber, Dirk Bartig, Bj örn Misselwitz, Armin Grau, Christos Krogias Source Type: research
Serum neurofilament light chain levels are associated with stroke severity and functional outcome in patients undergoing endovascular therapy for large vessel occlusion
We aimed to analyze serum neurofilament light chain (sNfL) levels in patients undergoing endovascular therapy (EVT) for anterior circulation large vessel occlusion (acLVO).
Source: Journal of the Neurological Sciences - August 31, 2021 Category: Neurology Authors: Jan Rahmig, Katja Akg ün, Erik Simon, Matthias Gawlitza, Christian Hartmann, Timo Siepmann, Lars-Peder Pallesen, Jessica Barlinn, Volker Puetz, Tjalf Ziemssen, Kristian Barlinn Tags: Clinical short communication Source Type: research
Re: Semerano A, Mamadou Z, Desilles JP, Sabben C, Bacigaluppi M, Piotin M, et al. Carotid webs in large vessel occlusion stroke: Clinical, radiological and thrombus histopathological findings. Journal of the neurological sciences. 2021;427:117550
We read with interest the manuscript entitled “Carotid webs in large vessel occlusion stroke: Clinical, radiological and thrombus histopathological findings“by Semerano et al., which adds to the body of literature related to the treatment of carotid webs [1].
Source: Journal of the Neurological Sciences - August 20, 2021 Category: Neurology Authors: Diogo C. Haussen, Alhamza R. Al-Bayati, Nirav Bhatt, Raul G. Nogueira Tags: Letter to the Editor Source Type: research
Prestroke cognitive decline in africans: Prevalence, predictors and association with poststroke dementia
Pre-existing cognitive decline is a risk factor for stroke onset and poststroke dementia. There is a knowledge gap on prestroke cognitive decline in indigenous Africans. We estimated prevalence and predictors of prestroke cognitive decline, as well as its association with poststroke dementia at one year in Nigerian survivors of a first ever stroke.
Source: Journal of the Neurological Sciences - August 18, 2021 Category: Neurology Authors: Akin Ojagbemi, Toyin Bello, Mayowa Owolabi, Olusegun Baiyewu Source Type: research
Hyperdense middle cerebral artery sign and response to combination of mechanical Thrombectomy plus intravenous thrombolysis in acute stroke patients
Combining intra-arterial mechanical thrombectomy (IAMT) and intravenous thrombolysis (IVT) has shown to have an excellent recanalization rate and better clinical outcome in acute ischemic stroke (AIS) patients. Hyperdense middle cerebral artery sign (HMCAS) on pretreatment non-contrast head CT scan of AIS patients is one of the early ischemic radiological findings in middle cerebral artery territory AIS. We aimed to evaluate whether the presence of HMCAS predicts the outcome of AIS patients receiving combination therapy with IAMT and IVT.
Source: Journal of the Neurological Sciences - August 16, 2021 Category: Neurology Authors: Ashkan Mowla, Seyed-Mostafa Razavi, Navdeep S. Lail, Pegah Mohammadi, Peyman Shirani, Katelyn S. Kavak, Robert N. Sawyer, Haris Kamal Source Type: research
Histopathologic analysis of retrieved cerebral thrombi in acute ischemic stroke patients with proximal anterior circulation occlusions amenable to endovascular thrombectomy
Dear Editor,
Source: Journal of the Neurological Sciences - August 14, 2021 Category: Neurology Authors: Gloria Mak, Jian-Qiang Lu, Kanjana Perera Tags: Letter to the Editor Source Type: research
Lesion topography of posterior cerebral artery infarcts
This study analyzed the topography of acute ischemic stroke in the posterior cerebral artery (PCA) territory. We studied 84 patients with unilateral ischemic PCA stroke. Patients were classified according to lesion levels as cortico-subcortical (superficial), combined (cortical and mesodiencephalic) or isolated thalamic. To receive a lesion map, data from acute MR and CT imaging were normalized and labelled automatically by mapping to stereotaxic anatomical atlases. Cortical lesions accounted for 41.7%, combined for 36.9%, and isolated thalamic lesions for 21.4%.
Source: Journal of the Neurological Sciences - July 23, 2021 Category: Neurology Authors: T. Benke, F. Dazinger, R. Pechlaner, K. Willeit, J. Clausen, M. Knoflach Source Type: research
Clinical profile and outcome of non-COVID strokes during pandemic and the pre pandemic period: COVID-Stroke Study Group (CSSG) India
As the health systems around the world struggled to meet the challenges of COVID-19 pandemic, care of many non-COVID emergencies was affected.
Source: Journal of the Neurological Sciences - July 15, 2021 Category: Neurology Authors: Rohit Bhatia, P.N. Sylaja, M.V. Padma Srivastava, Snigdha Komakula, Thomas Iype, Rajsrinivas Parthasarathy, Dheeraj Khurana, Vibhor Pardesani, Vijaya Pamidimukkala, S. Kumaravelu, Jeyaraj Pandian, Suman Kushwaha, Debashish Chowdhury, Salil Gupta, Srijithe Source Type: research
Changes in autonomic tone during delirium in acute stroke patients assessed by pupillometry and skin conductance
Delirium is a common complication in acute ischemic stroke, possibly caused by alterations in the regulation of the sympathetic autonomic nervous system. We investigated whether such an association could be demonstrated with two easy-to-use measurement techniques: Measurement of palmar skin conductance level (SCL) and pupillometry measuring the dilation velocity in the pupillary light reflex (PLRdil.vel.).The cohort study included 64 patients admitted with acute ischemic stroke. During the study period (median 4.1 days, interquartile range 2.1 days) patients were assessed for delirium once daily as well as with measur...
Source: Journal of the Neurological Sciences - July 14, 2021 Category: Neurology Authors: Jannik Stokholm, Lars Kristian Hebsgaard Birkmose, Abd Al Bari Omar Ahmed, Claudio Csillag, Troels Wesenberg Kj ær, Thomas Christensen Source Type: research
IV tPA given in the golden hour for emergent large vessel occlusion stroke improves recanalization rates and clinical outcomes
Early thrombolysis for acute ischemic stroke (AIS) due to emergent large vessel occlusion (ELVO) is associated with better clinical outcome. This is thought to be due to greater tissue salvage with earlier recanalization. We explored whether ultra-early administration of intravenous tissue plasminogen activator (IV tPA) within 60 min (Golden Hour) of symptom onset for AIS due to ELVO is associated with a higher rate of recanalization.
Source: Journal of the Neurological Sciences - July 14, 2021 Category: Neurology Authors: Rodica Di Lorenzo, Maher Saqqur, Andrew Blake Buletko, Lacy Sam Handshoe, Bhageeradh Mulpur, Julian Hardman, Megan Donohue, Dolora Wisco, Ken Uchino, M. Shazam Hussain Source Type: research
Influence of age on links between major modifiable risk factors and stroke occurrence in West Africa
BackgroundThe burden of stroke in Africa is high. Understanding how age associates with major modifiable stroke risk factors could inform tailored demographic stroke prevention strategies.PurposeTo quantify the magnitude and direction of the effect sizes of key modifiable stroke risk factors according to three age groups: 65 years (elderly) in West Africa.MethodsThis was a case-control study involving 15 sites in Ghana and Nigeria. Cases included adults aged ≥18 years with CT/MRI scan-typed stroke.
Source: Journal of the Neurological Sciences - July 8, 2021 Category: Neurology Authors: Fred S. Sarfo, Onoja Akpa, Bruce Ovbiagele, Albert Akpalu, Kolawole Wahab, Morenikeji Komolafe, Reginald Obiako, Lukman Owolabi, Godwin O. Osaigbovo, Carolyn Jenkins, Godwin Ogbole, Adekunle Fakunle, Hemant K. Tiwari, Oyedunni Arulogun, Donna K. Arnett, O Source Type: research
