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Source: Journal of the Neurological Sciences

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Total 856 results found since Jan 2013.

Discrepant relationships between admission blood pressure and mortality in different stroke subtypes
The relationship between blood pressure(BP) and clinical outcome in patients with acute stroke is still controversial. The present study aimed to elucidate the impact of admission blood pressure on mortality in patients with acute stroke of different subtypes. Data were from ChinaQUEST (QUality Evaluation of Stroke Care and Treatment), a multicenter, prospective hospital registry study in 37 cities across China. A total of 6427 patients were admitted within 24h of onset and after following up for 12months, 5501 were included in the final analysis.
Source: Journal of the Neurological Sciences - September 22, 2017 Category: Neurology Authors: Yuanyuan Liu, Yide Yang, Haiqiang Jin, Chenghe Fan, Pu Lv, Wei Sun, Qing Peng, Mingming Zhao, David K. Jin, Jiguang Wang, Lawrence K.S. Wong, Craig S. Anderson, Lemin Zheng, Yining Huang, ChinaQUEST (Quality Evaluation of Stroke Care and Treatment) Invest Source Type: research

Modification of the effects of age on clinical outcomes through management of lifestyle-related factors in patients with acute ischemic stroke
This study examined the association between age and clinical outcomes after ischemic stroke, and whether the effect of age on post-stroke outcomes can be modified by various factors.
Source: Journal of the Neurological Sciences - February 14, 2023 Category: Neurology Authors: Yuichiro Ohya, Ryu Matsuo, Noriko Sato, Fumi Irie, Yoshinobu Wakisaka, Tetsuro Ago, Masahiro Kamouchi, Takanari Kitazono, Investigators for Fukuoka Stroke Registry Source Type: research

Employment status, social function decline and caregiver burden among stroke survivors. A South Indian study
Conclusions: Loss of occupation among stroke survivors is high. The decline in social function among stroke survivors and caregivers was significant. Even though functional disability contributed to employment loss and social function decline among stroke survivors, it did not have a significant impact on caregiver burden.
Source: Journal of the Neurological Sciences - July 29, 2013 Category: Neurology Authors: Sapna Erat Sreedharan, J.P. Unnikrishnan, M.G. Amal, B.S. Shibi, Sankara Sarma, P.N. Sylaja Tags: Original Articles Source Type: research

Clinico-radiological predictors of vascular cognitive impairment (VCI) in patients with stroke: A prospective observational study
Conclusion: Post-stroke cognitive impairment is frequent and is associated with poor functional outcome. Predictors like lower educational status, strategic site lesion, greater severity of age related white matter changes and baseline stroke severity independently contributed to the risk of developing VCI in stroke patients.Highlights:
Source: Journal of the Neurological Sciences - March 31, 2014 Category: Neurology Authors: Tejendra Sukdeo Chaudhari, Rajesh Verma, Ravindra Kumar Garg, Manish Kumar Singh, Hardeep Singh Malhotra, Praveen kumar Sharma Tags: Original Articles Source Type: research

Frequent inaccuracies in ABCD2 scoring in non-stroke specialists' referrals to a daily Rapid Access Stroke Prevention service
Abstract: The ‘accuracy’ of age, blood pressure, clinical features, duration and diabetes (ABCD2) scoring by non-stroke specialists referring patients to a daily Rapid Access Stroke Prevention (RASP) service is unclear, as is the accuracy of ABCD2 scoring by trainee residents.In this prospective study, referrals were classified as ‘confirmed TIAs’ if the stroke specialist confirmed a clinical diagnosis of possible, probable or definite TIA, and ‘non-TIAs’ if patients had a TIA mimic or completed stroke. ABCD2 scores from referring physicians were compared with scores by experienced stroke specialists and neurol...
Source: Journal of the Neurological Sciences - July 19, 2013 Category: Neurology Authors: David Bradley, Simon Cronin, Justin A. Kinsella, W. Oliver Tobin, Ciara Mahon, Margaret O'Brien, Róisín Lonergan, Marie Therese Cooney, Sean Kennelly, D. Rónán Collins, Desmond O'Neill, Tara Coughlan, Shane Smyth, Dominick J.H. McCabe Tags: Original Articles Source Type: research

Incidence and 30-day case fatality rate of first-ever stroke in urban Nigeria: The prospective community based Epidemiology of Stroke in Lagos (EPISIL) phase II results
Conclusions: The stroke incidence in this urban sub-Saharan African community remains lower than that in emerging and developed economies, although the age- and gender-related trends and CFR are comparable to that in developed countries.
Source: Journal of the Neurological Sciences - May 30, 2013 Category: Neurology Authors: Mustapha A. Danesi, Njideka U. Okubadejo, Frank I. Ojini, Oluwadamilola O. Ojo Tags: Original Articles Source Type: research

Repeated intravenous thrombolysis after recurrent stroke. A case series and review of the literature
Conclusions: IV re-thrombolysis may be safe and effective when recurrent stroke occurs after a period of complete neurologic regression lasting at least 24h or minor disability (mRS score ≤2) lasting at least 3months since the previous stroke.Highlights:
Source: Journal of the Neurological Sciences - July 25, 2014 Category: Neurology Authors: Manuel Cappellari, Giuseppe Moretto, Paolo Bovi Tags: Original Articles Source Type: research

Associations between stroke type, stroke severity, and pre-stroke osteoporosis with the risk of post-stroke fracture: A nationwide population-based study
BackgroundRecognizing the post-stroke fracture risk factors is crucial for targeted intervention and primary fracture prevention. We aimed to investigate whether stroke types, stroke severity, and pre-stroke osteoporosis are associated with post-stroke fracture.MethodsIn a nationwide cohort, we identified previously fracture-free patients who suffered from first-ever stroke, either acute ischemic stroke (AIS) or intracerebral hemorrhage (ICH), between 2003 and 2015. Information regarding stroke severity, osteoporosis, comorbidity, and medication information was collected.
Source: Journal of the Neurological Sciences - May 27, 2021 Category: Neurology Authors: Hung-Ping Wang, Sheng-Feng Sung, Hsin-Yi Yang, Wan-Ting Huang, Cheng-Yang Hsieh Source Type: research

Stroke-prone renovascular hypertensive rat as an animal model for stroke studies: From artery to brain
Abstract: High blood pressure is a main risk factor for both initial and recurrent stroke. Compared to the poststroke situation in normotension, the brain lesion is larger in hypertension, and the treatments may not be as effective. Thus, the results from healthy individuals may not be directly applied to the hypertensive. In fact, the high prevalence of hypertension in stroke patients and its devastating effect urge the necessity to integrate arterial hypertension in the study of stroke in order to better mimic the clinical situations. The first step to do so is to have an appropriate hypertensive animal model for stroke ...
Source: Journal of the Neurological Sciences - August 19, 2013 Category: Neurology Authors: Song-Jie Liao, Ru-Xun Huang, Zhen-Pei Su, Jin-Sheng Zeng, Jian-Wei Mo, Zhong Pei, Ling Li, Yan-Nan Fang, Hua Hong, Hai-Wei Huang Tags: Review Source Type: research

Validity, reliability and minimum detectable change of the maximum step length test in people with stroke
Abstract: Stroke is a significant cause of deficits in balance, mobility and disability. Although tests of stepping speed are associated with balance performance after stroke, relationships between clinical tests of stepping distance and balance performance have not been investigated in people with stroke. A validated test of stepping distance and balance in older adults (the maximum step length [MSL] test), and two clinical measures associated with balance in people with stroke (the five-times-sit-to-stand test [FTSST] and gait speed) were evaluated in nineteen independent community-dwelling people with chronic stroke. Th...
Source: Journal of the Neurological Sciences - December 26, 2012 Category: Neurology Authors: Vicky Pardo, Dale Knuth, Bridget McDermott, Joseph Powell, Allon Goldberg Tags: Original Articles Source Type: research

Association of ALOX5AP1 SG13S114T/A variant with ischemic stroke, stroke subtypes and aspirin resistance
Abstract: The important role of genetic variants in the etiology and pathophysiology of stroke is being increasingly recognized. Simultaneously, the influence of genetic factors in the clinical outcome of drug therapy cannot be ignored. 5-lipoxygenase activating (ALOX5AP) gene involved in the synthesis of leukotrienes, has been recognized as an important gene contributing towards susceptibility of stroke risk. Leukotrienes are involved in the physiological mechanism of atherosclerotic events and inflammation. The present study was designed to identify the association of SG13S114T/A polymorphism in ALOX5AP1 gene with risk o...
Source: Journal of the Neurological Sciences - June 10, 2013 Category: Neurology Authors: Vandana Sharma, Sneha Dadheech, Subhash Kaul, A. Jyothy, Anjana Munshi Tags: Original Articles Source Type: research

The impact of stroke on cognitive processing — A prospective event-related potential study
Conclusions: Our results suggest that ERP measurement is an appropriate method for diagnosis and follow-up of cognitive changes after ischemic stroke. In particular the P3 component is an indicator for patients at risk for reinfarction.Highlights:
Source: Journal of the Neurological Sciences - February 27, 2014 Category: Neurology Authors: Leandra Stahlhut, Karl-Heinz Grotemeyer, Ingo-W. Husstedt, Stefan Evers Tags: Original Articles Source Type: research

Risk factors for stroke among patients with hypertension: A case–control study
Abstract: Background: In some African countries, more than half of the adult population are estimated to be hypertensive leading to an escalated burden of stroke in the continent. We conducted the first study to unravel the major risk factors for stroke among hypertensive patients (Nigerian-Africans) using a case–control design while also exploring the relative contributions of carotid intima medial thickness (CIMT) and carotid diameter as risk markers for stroke.Methods: Using conventional techniques, stroke-related demographic, clinical and laboratory data were obtained from 135 consecutive volunteering hypertensive st...
Source: Journal of the Neurological Sciences - December 20, 2012 Category: Neurology Authors: M.O. Owolabi, A.M. Agunloye Tags: Original Articles Source Type: research