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Source: Journal of the Neurological Sciences

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Total 856 results found since Jan 2013.

Haemorrhagic transformation in ischaemic stroke is more frequent than clinically suspected – A neuropathological study
The vast majority of literature on the frequency of the haemorrhagic transformation of ischaemic stroke is based on imaging studies. The purpose of the present study was to assess the added value of autopsy and neuropathological analysis in a neurology centre with emphasis on acute stroke care.
Source: Journal of the Neurological Sciences - June 24, 2016 Category: Neurology Authors: Rita Szepesi, Ákos Csokonay, Balázs Murnyák, Mahan C. Kouhsari, Gergely Hofgárt, László Csiba, Tibor Hortobágyi Source Type: research

High-sensitivity cardiac troponin T levels and risk of cerebral microbleeds in acute ischemic stroke patients with atrial fibrillation and/or rheumatic heart disease
Elevated high-sensitivity cardiac troponin T (hs-cTnT) levels are associated with coronary disease and small-vessel ischemic stroke through their associations with atherosclerosis. Considering the relationship between atherosclerosis and cerebral microbleeds (CMBs), the purpose of this study was to examine associations between serum hs-cTnT levels and risk of CMBs in acute ischemic stroke patients.
Source: Journal of the Neurological Sciences - August 1, 2016 Category: Neurology Authors: Junfeng Liu, Deren Wang, Yao Xiong, Bian Liu, Chenchen Wei, Zhenxing Ma, Bo Wu, Hehan Tang, Ming Liu Source Type: research

Characteristic lesion pattern and echocardiographic findings in extra-cardiac shunt-related stroke
Among embolic strokes of undetermined source, under-recognized etiology such as extra-cardiac shunt could be a potential risk factor. We sought to characterize infarction patterns on diffusion-weighted imaging (DWI) and transesophageal echocardiography (TEE) findings in extra-cardiac shunt-related stroke. We enrolled 96 consecutive patients with cryptogenic stroke who had an extra- or intra-cardiac shunt. Diagnosis of the shunt was performed using TEE with agitated saline contrast and pulmonary vein isolation.
Source: Journal of the Neurological Sciences - August 10, 2016 Category: Neurology Authors: Jun-Kyu Mun, Sung Ji Park, Suk Jae Kim, Young Bang Oh, Chin-Sang Chung, Kwang Ho Lee, Gyeong-Moon Kim Source Type: research

Botulinum toxin as early intervention for spasticity after stroke or non-progressive brain lesion: A meta-analysis
Spasticity is a functionally limiting disorder that commonly occurs following stroke or severe brain injury, and may lead to disability and pain. In tandem with neurorehabilitation, botulinum toxin type A (BoNT-A) is the recommended first-line treatment for spasticity and, to date, the majority of trials have reported BoNT-A use in patients>6months after ictus. The present meta-analysis aimed to evaluate the effects of early BoNT-A injection for post-stroke spasticity on improvements in hypertonicity, disability, function and associated pain.
Source: Journal of the Neurological Sciences - October 8, 2016 Category: Neurology Authors: Raymond L. Rosales, Fran Efendy, Ericka SA Teleg, Mary MD Delos Santos, Mary CE Rosales, Marc Ostrea, Michelle J Tanglao, Arlene R. Ng Source Type: research

Does stroke etiology play a role in predicting outcome of acute stroke patients who underwent endovascular treatment with stent retrievers?
The goal of the study was to identify whether the stroke etiology play a role in the recanalization and outcome of patients who underwent mechanical thrombectomy with stent retrievers.
Source: Journal of the Neurological Sciences - November 9, 2016 Category: Neurology Authors: Semih Giray, Ozcan Ozdemir, Demet F. Bas, Yusuf İnanc, Zulfikar Arlier, Ozcan Kocaturk, Huseyin Yazici Source Type: research

Therapeutic route of patients at the acute phase of their stroke in Burkina Faso
The advent of the neurovascular units and thrombolysis has improved support for stroke in developed countries. Our objective was to study the therapeutic route of stroke patients in Burkina Faso, a country with limited resources.
Source: Journal of the Neurological Sciences - November 13, 2016 Category: Neurology Authors: Napon Christian, Dabilgou Anselme, Kyelem Julie, Bonkoungou Papougn ézambo, Kaboré Jean Tags: Clinical short communication Source Type: research

Hemorrhagic transformation and cerebral edema in acute ischemic stroke: Link to cerebral autoregulation
We examined the relationship between dynamic cerebral autoregulation (CA) in the early hours post ischemia, and the risk of developing hemorrhagic transformation and cerebral edema at 24h post stroke
Source: Journal of the Neurological Sciences - November 28, 2016 Category: Neurology Authors: Pedro Castro, Elsa Azevedo, Jorge Serrador, Isabel Rocha, Farzaneh Sorond Source Type: research

The test accuracy of the Montreal Cognitive Assessment (MoCA) by stroke lateralisation
The Montreal Cognitive Assessment (MoCA) is an increasingly popular screening tool for detecting cognitive impairment post-stroke. However its' test accuracy by stroke lateralisation is as yet unknown.
Source: Journal of the Neurological Sciences - December 18, 2016 Category: Neurology Authors: Edgar Chan, Samantha Altendorff, Colm Healy, David J. Werring, Lisa Cipolotti Tags: Clinical Short Communication Source Type: research

Administration of a pictorial questionnaire to screen for stroke among patients with hypertension or diabetes in rural Ghana
Stroke prevention is an important public health goal in low-and-middle income countries (LMIC) due to its high mortality and morbidity in these settings. Epidemiological data from high-income countries have demonstrated a potent predictive association between self-reported stroke symptoms and risks of future strokes, incident cognitive impairment and all-cause mortality.
Source: Journal of the Neurological Sciences - January 6, 2017 Category: Neurology Authors: Fred S. Sarfo, Rexford Adu Gyamfi, Sheila Adamu, Osei Sarfo-Kantanka, Mayowa Owolabi, Bruce Ovbiagele Source Type: research

Clinical significance of changes in serum neuroglobin and HIF-1 α concentrations during the early-phase of acute ischemic stroke
Neuroglobin (NGB) has been described as a neuroprotective agent in cerebral ischemia, hypoxia inducible factor (HIF) has shown an important role in modulating hypoxic and ischemic injury, and therefore they have the potential to impact outcomes after acute ischemic stroke (AIS). Thus, we investigated early changes in the concentrations of serum NGB and HIF-1 α after AIS and evaluated the relations of both NGB and HIF-1α to stroke severity and prognosis.
Source: Journal of the Neurological Sciences - January 13, 2017 Category: Neurology Authors: Lixia Xue, Hao Chen, Kaili Lu, Jiankang Huang, Hao Duan, Yuwu Zhao Source Type: research

Age, sex, and race/ethnic temporal trends in metabolic syndrome prevalence among individuals with myocardial infarction or stroke in the United States
Metabolic syndrome (MetS), an independent risk factor for myocardial infarction (MI) and stroke, affects 1 in 3 adults in the United States. Recent trends in MetS prevalence among MI and stroke survivors are unknown.
Source: Journal of the Neurological Sciences - January 31, 2017 Category: Neurology Authors: Alain Lekoubou, Bruce Ovbiagele, Daniela Markovic, Nerses Sanossian, Amytis Towfighi Source Type: research

Stroke-related stigma among West Africans: Patterns and predictors
Disability-adjusted life-years lost after stroke in Low& Middle-Income Countries (LMICs) is almost seven times those lost in High-income countries. Although individuals living with chronic neurological and mental disorders are prone to stigma, there is a striking paucity of literature on stroke-related stigma particularly from LMICs.
Source: Journal of the Neurological Sciences - February 7, 2017 Category: Neurology Authors: Fred Stephen Sarfo, Michelle Nichols, Suparna Qanungo, Abeba Teklehaimanot, Arti Singh, Nathaniel Mensah, Raelle Saulson, Mulugeta Gebregziabher, Uvere Ezinne, Mayowa Owolabi, Carolyn Jenkins, Bruce Ovbiagele Source Type: research

Stroke severity predicts poststroke delirium and its association with dementia: Longitudinal observation from a low income setting
The effect of delirium on stroke outcome has not been quantified in sub-Saharan Africa. We investigated the prevalence of delirium occurring within one week of stroke in Nigerian survivors and its association with dementia and mortality at 3months.
Source: Journal of the Neurological Sciences - February 17, 2017 Category: Neurology Authors: Akin Ojagbemi, Mayowa Owolabi, Toyin Bello, Olusegun Baiyewu Source Type: research

Mechanical embolectomy for acute ischemic stroke beyond six hours from symptom onset using MRI based perfusion imaging
There is very limited data on the use of MRI based perfusion imaging to select patients with acute ischemic stroke and large vessel occlusion (LVO) for intraarterial therapy beyond 6h from onset. Our aim is to report the outcome of patients with acute ischemic stroke and large artery occlusion who presented beyond 6h from onset, had favorable MRI imaging profile, and underwent mechanical embolectomy.
Source: Journal of the Neurological Sciences - February 20, 2017 Category: Neurology Authors: Ryan A. McTaggart, Shadi Yaghi, Daniel C Sacchetti, Richard A. Haas, Morgan Hemendinger, Daniel Arcuri, Jeffrey M. Rogg, Karen L. Furie, Mahesh V. Jayaraman Source Type: research

Association between PTGS1 polymorphisms and functional outcomes in Chinese patients with stroke during aspirin therapy: Interaction with smoking
We examined the effects of PTGS1 polymorphisms, smoking status, and their interaction on functional outcomes in a cohort of Chinese Han patients with stroke during aspirin therapy.
Source: Journal of the Neurological Sciences - March 12, 2017 Category: Neurology Authors: Huan Cai, Biyang Cai, Lingli Sun, Hao Zhang, Shuyu Zhou, Liping Cao, Hongquan Guo, Wen Sun, Bernard Yan, Stephen M. Davis, Zhizhong Zhang, Xinfeng Liu Source Type: research