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Source: Journal of the Neurological Sciences

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Total 856 results found since Jan 2013.

Level of consciousness at discharge and associations with outcome after ischemic stroke
Many factors may potentially complicate the stroke recovery process, including persistently impaired level of consciousness (LOC) —whether from residual stroke effects or from superimposed delirium. We aimed to determine the degree to which impaired LOC at hospital discharge is associated with outcomes after ischemic stroke.
Source: Journal of the Neurological Sciences - April 14, 2018 Category: Neurology Authors: Michael E. Reznik, Shadi Yaghi, Mahesh V. Jayaraman, Ryan A. McTaggart, Morgan Hemendinger, Brian C. Mac Grory, Tina M. Burton, Shawna M. Cutting, Bradford B. Thompson, Linda C. Wendell, Ali Mahta, N. Stevenson Potter, Lori A. Daiello, Cyrus M. Kosar, Ric Source Type: research

Hemoglobin level and three-month clinical outcomes among ischemic stroke patients with elevated systolic blood pressure
Previous studies have reported that extreme low and high hemoglobin levels are positively associated with the risk of ischemic stroke. However, there are few reports on the relationship between hemoglobin at acute phase and clinical outcomes after ischemic stroke and the results of their association to date are inconsistent. We aimed to investigate the association between them in a large prospective cohort of ischemic stroke patients.
Source: Journal of the Neurological Sciences - November 27, 2018 Category: Neurology Authors: Daoxia Guo, Zhengbao Zhu, Chongke Zhong, Hao Peng, Tian Xu, Aili Wang, Yanbo Peng, Tan Xu, Chung-Shiuan Chen, Yongqiu Li, Zhong Ju, Jing Chen, Yonghong Zhang, Jiang He Source Type: research

A startling acoustic stimulation (SAS)-TMS approach to assess the reticulospinal system in healthy and stroke subjects
Reticulospinal (RS) hyperexcitability is observed in stroke survivors with spastic hemiparesis. Habituated startle acoustic stimuli (SAS) can be used to stimulate the RS pathways non-reflexively. However, the role of RS pathways in motor function and its interactions with the corticospinal system after stroke still remain unclear. Therefore, the purpose of this study was to investigate the effects of conditioning SAS on the corticospinal system in healthy subjects and in stroke subjects with spastic hemiparesis.
Source: Journal of the Neurological Sciences - February 11, 2019 Category: Neurology Authors: Yen-Ting Chen, Shengai Li, Ping Zhou, Sheng Li Source Type: research

Ischemic stroke during anticoagulant interruption by healthcare professionals in stroke patients with atrial fibrillation
Anticoagulant therapy often requires temporary interruption. Nevertheless, the frequency and clinical characteristics of stroke patients who develop stroke during anticoagulant interruption are not fully known.
Source: Journal of the Neurological Sciences - March 19, 2019 Category: Neurology Authors: Yuki Sakamoto, Seiji Okubo, Chikako Nito, Yasuhiro Nishiyama, Satoshi Suda, Noriko Matsumoto, Junya Aoki, Takashi Shimoyama, Takuya Kanamaru, Kanako Muraga, Kentaro Suzuki, Masahiro Mishina, Kazumi Kimura Source Type: research

Accurate etiology diagnosis in patients with stroke and atrial fibrillation: A role for brain natriuretic peptide
Atrial fibrillation (AF) is the leading cause of cardioembolic stroke (CES), and patients with stroke and AF are frequently assumed to have CES. However, strokes presumably due to atherosclerotic pathophysiologies in large or small vessels can also occur in patients with AF. The aims of the present study were to clarify the prevalence of and factors related to a non-cardioembolic etiology in acute stroke patients with AF.
Source: Journal of the Neurological Sciences - March 28, 2019 Category: Neurology Authors: Yuki Sakamoto, Chikako Nito, Yasuhiro Nishiyama, Satoshi Suda, Noriko Matsumoto, Junya Aoki, Takashi Shimoyama, Takuya Kanamaru, Kentaro Suzuki, Yuki Go, Masahiro Mishina, Kazumi Kimura Source Type: research

Do acute stroke patients develop hypocapnia? A systematic review and meta-analysis
Purpose: Carbon dioxide (CO2) is a potent cerebral vasomotor agent. Despite reduction in CO2 levels (hypocapnia) being described in several acute diseases, there is no clear data on baseline CO2 values in acute stroke. The aim of the study was to systematically assess CO2 levels in acute stroke. Material and methods: Four online databases, Web of Science, MEDLINE, EMBASE and CENTRAL, were searched for articles that described either partial pressure of arterial CO2 (PaCO2) and end-tidal CO2 (EtCO2) in acute stroke.
Source: Journal of the Neurological Sciences - April 29, 2019 Category: Neurology Authors: Angela S.M. Salinet, Jatinder S. Minhas, Ronney B. Panerai, Edson Bor-Seng-Shu, Thompson G. Robinson Tags: Review Article Source Type: research

Estimating morbidity due to stroke in Nigeria: a systematic review and meta-analysis
The response to stroke in Nigeria is impaired by inadequate epidemiologic information. We sought to collate available evidence and estimate the incidence of stroke and prevalence of stroke survivors in Nigeria.
Source: Journal of the Neurological Sciences - May 22, 2019 Category: Neurology Authors: Davies Adeloye, Martinsixtus Ezejimofor, Asa Auta, Rex G. Mpazanje, Nnenna Ezeigwe, Evelyn N. Ngige, Michael O. Harhay, Wondimagegnehu Alemu, Isaac F. Adewole Source Type: research

Ultra-early improvement after endovascular thrombectomy and long-term outcome in anterior circulation acute ischemic stroke
The use of post-treatment measures after acute ischemic stroke is important to predict good functional outcome. The most studied is 24  h National Institutes of Health Stroke Scale (NIHSS) score and existing literature is scarce regarding the use of earlier indicators, namely NIHSS immediately after endovascular thrombectomy (EVT). We hypothesized that an immediate neurological improvement after EVT, that we called ultra-early ne urological improvement (UENI), would be a reliable functional independence predictor in anterior circulation acute ischemic stroke patients.
Source: Journal of the Neurological Sciences - January 4, 2020 Category: Neurology Authors: Ant ónioMartins de Campos, Andreia Carvalho, Marta Rodrigues, Sofia Figueiredo, Tiago Gregório, Henrique Costa, Ludovina Paredes, André Cunha, Sérgio Castro, Manuel Ribeiro, Miguel Veloso, Pedro Barros Source Type: research

Influence of oral anticoagulation on stroke severity and outcomes: A propensity score matching case-control study
Oral anticoagulants (OAC) such as vitamin K antagonists (VKA) and direct-acting OACs (DOAC) remain the mainstay for prevention of cardioembolic stroke. The influence of previous OAC treatment on stroke severity and outcomes is not well stablished. We compared patients with incident cardioembolic strokes according to pre-stroke treatment.
Source: Journal of the Neurological Sciences - January 13, 2020 Category: Neurology Authors: A. Plaza Herr áiz, L. Lobato-Pérez, M. Ramírez-Torres, I. De Lorenzo, M. Alonso de Leciñana, E. Díez-Tejedor, B. Fuentes, J. Rodríguez-Pardo Source Type: research

Vascular-brain Injury Progression after Stroke (VIPS) study: concept for understanding racial and geographic determinants of cognitive decline after stroke
Cognitive impairment and dementia (CID) are major public health problems with substantial personal, social, and financial burdens. African Americans are at a heightened risk for Vascular Cognitive Impairment (VCI) compared to European Americans. Recent lines of evidence also suggest a high burden of Post-stroke VCI among indigenous Africans. A better understanding of the cause(s) of the racial disparity in CID, specifically VCI, is needed in order to develop strategies to reduce it.We propose and discuss the conceptual framework for a unique tri-population, trans-continental study titled The Vascular brain Injury Progressi...
Source: Journal of the Neurological Sciences - February 18, 2020 Category: Neurology Authors: Fred Stephen Sarfo, Rufus Akinyemi, George Howard, Virginia J. Howard, Kolawole Wahab, Mary Cushman, Deborah A. Levine, Adesola Ogunniyi, Fred Unverzagt, Mayowa Owolabi, Bruce Ovbiagele Tags: Review Article Source Type: research

Primary aldosteronism in young adults with acute stroke: Prevalence and clinical characteristics
The objectives of the study were to investigate the prevalence of PA in patients under 45  years old with history of acute stroke and the clinical characteristics during stroke attack. We retrieved the medical records of 116 patients once admitted due to acute stroke and cross-sectionally conducted screening test as well as confirmatory test among those patients.
Source: Journal of the Neurological Sciences - March 10, 2020 Category: Neurology Authors: Ziwei Tang, Haiyan Chen, Wenwen He, Linqiang Ma, Ying Song, Mei mei, Ting Luo, Zhipeng Du, Jinbo Hu, Shumin Yang, Qingfeng Cheng, Zhihong Wang, Qifu Li, the Chongqing Primary Aldosteronism Study(CONPASS) Group Source Type: research

Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes due to m.3243A   >  G mutation in a 76-year-old woman
Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) with m.3243A  > G mutation is a common type of mitochondrial disease [1,2]. Most patients with MELAS develop stroke-like episodes before the age of 40, a criterion of MELAS [3]. However, increasing reports have demonstrated that elderly subjects (≥ 60 years old) may develop this mitochondrial encephalopathy [4,5]. Here, we report a 76-year-old woman who was previously healthy without any organ dysfunction related to mitochondrial abnormalities (except for a mild hearing disability) and developed encephalopathy accompanied by st...
Source: Journal of the Neurological Sciences - March 18, 2020 Category: Neurology Authors: Kana Ueki, Yoshinobu Wakisaka, Kuniyuki Nakamura, Yuji Shono, Shinichi Wada, Yoji Yoshikawa, Yuta Matsukuma, Takeshi Uchiumi, Dongchong Kang, Takanari Kitazono, Tetsuro Ago Tags: Letter to the Editor Source Type: research

Stroke and HIV in Botswana: A prospective study of risk factors and outcomes
HIV is associated with an increased risk of stroke, but there are sparse data on risk factors for stroke in people living with HIV in Sub-Saharan African. The goal of this study was to identify HIV-specific stroke characteristics and risk factors among adults in Botswana.
Source: Journal of the Neurological Sciences - March 25, 2020 Category: Neurology Authors: David R. Bearden, Bernard Omech, Ikanyeng Rulaganyang, Sheikh O. Sesay, Dennis L. Kolson, Scott E. Kasner, Michael T. Mullen Source Type: research

Evaluation of oxidative stress-related genetic variants for predicting stroke in patients with sickle cell anemia
Overt stroke in adults with sickle cell anemia (SCA) continues to be a major cause of morbidity and mortality, while no evidence-based strategy for prevention has been reached so far. Although transcranial Doppler ultrasonography represents the most important tool for identifying young patients with SCA at risk of primary stroke, strategies for stroke prediction in adulthood remain challenging. Emerging data suggest that oxidative stress may exert a pivotal role in the pathogenesis of ischemic brain injury.
Source: Journal of the Neurological Sciences - April 15, 2020 Category: Neurology Authors: Igor F. Domingos, Diego A. Pereira-Martins, Rayssa L. Borges-Medeiros, Diego A. Falcao, Betania L. Hatzlhofer, John N. Brewin, Kate Gardner, Taciana F. Mendonca, Maria S. Cavalcanti, Anderson F. Cunha, Ana C. Anjos, Evandra S. Rodrigues, Simone Kashima, P Source Type: research