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Source: Journal of the Neurological Sciences

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Total 856 results found since Jan 2013.

Stroke and sexual dysfunction — A narrative review
Sexual function is an essential part of quality of life in adults. However, sexual dysfunction (SD) in stroke survivors is a common but under-recognized complication after stroke. It is frequently neglected by patients and clinicians. The etiology of post-stroke SD, which is multifactorial includes anatomical, physical and psychological factors. Complete return of sexual function is an important target for functional recovery after stroke, so clinicians need to be aware of this issue and take a lead role in addressing this challenge in stroke survivors.
Source: Journal of the Neurological Sciences - February 5, 2015 Category: Neurology Authors: Jong-Ho Park, Bruce Ovbiagele, Wuwei Feng Tags: Review article Source Type: research

The homocysteine associated variant rs548987 of SLC17A3 confers susceptibility to ischemic stroke in Chinese population
Ischemic stroke is a common cause of death due to obstructed blood supply of the brain. Despite growing numbers of research, etiology underlying ischemic stroke remains complex and elusive. Elevated plasma homocysteine has been known as a risk factor for ischemic stroke. Recently, a genome-wide association study reported association between rs548987 of SLC17A3 and homocysteine. Given existing relation between homocysteine and ischemic stroke, SLC17A3 was believed to be a promising candidate gene of ischemic stroke.
Source: Journal of the Neurological Sciences - August 17, 2016 Category: Neurology Authors: Shouqing Huang, Lianhua Yin, Yihui Xu, Chunyan Zou, Lidian Chen Source Type: research

1.4 times increase in atrial fibrillation-related ischemic stroke and TIA over 12years in a stroke center
Prevalence of atrial fibrillation (AF) has quadrupled in the past 50years in the general population. However, there is uncertainty regarding prevalence of AF over time in ischemic stroke patients given the aging population and enhanced surveillance of AF. We aimed to explore the changing prevalence of AF as well as other risk factors, stroke subtypes, investigations and pre-stroke medications among ischemic stroke and transient ischemic attack (TIA) patients.
Source: Journal of the Neurological Sciences - May 11, 2017 Category: Neurology Authors: Qiong Yang, Leonid Churilov, Dongsheng Fan, Stephen Davis, Bernard Yan Source Type: research

Management of post-stroke depression in the Middle East and North Africa: Too little is known
Stroke is among the most common disabilities among adults and most stroke victims live in developing countries. However, little is known about services delivered in these countries for post-stroke depression, a common comorbidity that influences functional outcomes of stroke. In this paper, a physician from Syria reviews the literature on post-stroke depression among patients living in countries of the Middle East and North Africa region in order to examine whether current practices can be improved.
Source: Journal of the Neurological Sciences - May 12, 2017 Category: Neurology Authors: M. Ihsan Kaadan, Mary Jo Larson Tags: Review Article Source Type: research

Association of Ambulatory Blood Pressure Monitoring parameters with the Framingham Stroke Risk Profile
The Framingham Stroke Risk Profile (FSRP) is a novel and reliable tool for estimating the 10-year probability for incident stroke in stroke-free individuals, while the predictive value of ambulatory blood pressure monitoring (ABPM) for first-ever and recurrent stroke has been well established. We sought to evaluate cross-sectionally the association of ABPM parameters with FSRP score in a large sample of 2343 consecutive stroke-free individuals (mean age: 56.0 ±12.9, 49.1% male) who underwent 24-hour ABPM.
Source: Journal of the Neurological Sciences - July 5, 2017 Category: Neurology Authors: Georgios Tsivgoulis, Maria Pikilidou, Aristeidis H. Katsanos, Kimon Stamatelopoulos, Fotios Michas, Aikaterini Lykka, Christina Zompola, Angeliki Filippatou, Efstathios Boviatsis, Konstantinos Voumvourakis, Nikolaos Zakopoulos, Efstathios Manios Source Type: research

Microbubble signal and trial of org in acute stroke treatment (TOAST) classification in ischemic stroke
Right-to-left shunt (RLS) through a patent foramen ovale (PFO) is likely associated with ischemic stroke. Many studies have attempted to demonstrate the association between RLS and ischemic stroke. However, information on the association between the degree of RLS and the subtypes of ischemic stroke categorized by the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) classification is lacking.
Source: Journal of the Neurological Sciences - April 20, 2018 Category: Neurology Authors: Chan-Hyuk Lee, Hyun Goo Kang, Ji Sung Lee, Han Uk Ryu, Seul-Ki Jeong Source Type: research

Estimated glomerular filtration rate and incident stroke in patients with hypertension and/or diabetes
Sarfo et al. conducted a prospective study to evaluate the effect of estimated glomerular filtration rate (eGFR) on incident stroke in patients with hypertension and/or type 2 diabetes mellitus [1]. The authors had reported the risk factors of incident stroke in patients with hypertension and/or type 2 diabetes mellitus by using the same database [2]. They recognized 54 events of stroke and stroke incidence rates increased with decreasing eGFR. Adjusted hazard ratios (HRs) (95% confidence intervals [CIs]) of eGFR with 60 –89 ml/min, 30–59 ml/min, and89  ml/min for incident stroke were 1.42 (0.63–3.21), 1.88 (1....
Source: Journal of the Neurological Sciences - December 27, 2018 Category: Neurology Authors: Tomoyuki Kawada Tags: Letter to the Editor Source Type: research

COVID-19 AND STROKE: Experience in a GHANAIAN healthcare system
Background:The novel coronavirus disease 19 (COVID-19) causes multi-system disease including possibly heightened stroke risk. Data from high-income countries (HIC) suggest disruptions to care delivery with reduced stroke admissions and administration of acute stroke reperfusion therapies. We are unaware of any published data on the impact of the COVID-19 pandemic on stroke admissions and outcomes in sub-Saharan Africa.Purpose: To compare rates of stroke admissions and case fatality between corresponding periods in 2020 and 2019, within a hospital system in Ghana, to assess the potential impact of the COVID-19 pandemic.
Source: Journal of the Neurological Sciences - July 14, 2020 Category: Neurology Authors: Fred S. Sarfo, Naa Oboshie Mensah, Francis Agyapong Opoku, Nathaniel Adusei-Mensah, Michael Ampofo, Bruce Ovbiagele Source Type: research

Stroke and stroke prevention in sickle cell anemia in developed and selected developing countries
This comprehensive review provides an insight into the pathophysiology, epidemiology, evaluation, and treatment of sickle cell anemia (SCA)-related stroke in developed and developing countries. Vascular injury, hypercoagulability and vaso-occlusion play a role in the pathophysiology of stroke in SCA. Transcranial Doppler ultrasound (TCD) has lowered the incidence of ischemic stroke from 11% to 1% as TCD identifies children who are at risk for stroke, providing opportunities for interventions to reduce this risk.
Source: Journal of the Neurological Sciences - May 26, 2021 Category: Neurology Authors: Pallab Bhattacharya, Deepaneeta Sarmah, Kunjan R. Dave, Avirag Goswami, Mitsuyoshi Watanabe, Xin Wang, Kiran Kalia, Nikolaus Plesnila, Dileep R. Yavagal, Ofelia Alvarez Tags: Review Article Source Type: research

Influence of age on links between major modifiable risk factors and stroke occurrence in West Africa
BackgroundThe burden of stroke in Africa is high. Understanding how age associates with major modifiable stroke risk factors could inform tailored demographic stroke prevention strategies.PurposeTo quantify the magnitude and direction of the effect sizes of key modifiable stroke risk factors according to three age groups: 65 years (elderly) in West Africa.MethodsThis was a case-control study involving 15 sites in Ghana and Nigeria. Cases included adults aged ≥18 years with CT/MRI scan-typed stroke.
Source: Journal of the Neurological Sciences - July 8, 2021 Category: Neurology Authors: Fred S. Sarfo, Onoja Akpa, Bruce Ovbiagele, Albert Akpalu, Kolawole Wahab, Morenikeji Komolafe, Reginald Obiako, Lukman Owolabi, Godwin O. Osaigbovo, Carolyn Jenkins, Godwin Ogbole, Adekunle Fakunle, Hemant K. Tiwari, Oyedunni Arulogun, Donna K. Arnett, O Source Type: research

Mission thrombectomy 2020 (MT2020+) surveys of Caribbean stroke services: A call for action in our region
Stroke is the leading cause of death and adult-onset disability in the Caribbean region. Despite the tremendous advances in acute stroke care in the past 25  years, treatment in the Caribbean lags stroke standards of care. Mission Thrombectomy 2020+ (MT2020+) is a metrics based global campaign focused on increasing access to organized stroke care and mechanical thrombectomy.We conducted two consecutive online surveys across the MT2020+ Caribbean Regio n assessing access to thrombolytics, mechanical thrombectomy and stroke centers.
Source: Journal of the Neurological Sciences - March 31, 2023 Category: Neurology Authors: Gillian Gordon Perue, Ryna Then, Francene Gayle, Siddharth Galav, Yuvateja Thotamalla, Madihah Hepburn, Daidre Rowe, Luis Suazo, Cosme Villam án, Herbert Manosalva, Santiago Ortega-Gutierrez, Dileep Yavagal, Violiza Inoa, On behalf of MT2020+ Caribbean I Source Type: research

Early blood-based microbiological testing is ineffective in severe stroke patients
Conclusions: Very early bacteremia seems not to be a feature of severe stroke in patients despite signs of early immune system depression and frequent subsequent evidence of infection including pneumonia. Consequently our data suggests, that routine early blood-based standard or molecular microbiological assays do not reveal bacteremia, this finding questions the usefulness of their routine performance in this context.
Source: Journal of the Neurological Sciences - January 28, 2013 Category: Neurology Authors: Christoph Gumbinger, Andreas Hug, Bettina Mürle, Benjamin Berger, Markus Zorn, Klaus-Peter Becker, Stefan Zimmermann, Alexander H. Dalpke, Roland Veltkamp Tags: Original Articles Source Type: research

Increased circulating endothelial progenitor cells in patients with haemorrhagic and ischaemic stroke: The role of Endothelin-1
Abstract: Ischaemic stroke induces endothelial progenitor cell (EPC) mobilisation from bone marrow into peripheral blood. Circulating EPCs play an important role in post-injury regeneration of vasculature, whereas endothelial cells (ECs) have been shown to reflect endothelial damage and may be responsible for increased Endothelin-1 (ET-1) expression. We investigated herein the association between numbers of circulating ECs and EPCs, the levels of soluble factors regulating their migration and function, and the clinical outcome in patients with haemorrhagic (HS) or ischaemic stroke (IS). Sixteen patients with HS and eightee...
Source: Journal of the Neurological Sciences - January 7, 2013 Category: Neurology Authors: E. Paczkowska, M. Gołąb-Janowska, A. Bajer-Czajkowska, A. Machalińska, P. Ustianowski, M. Rybicka, P. Kłos, V. Dziedziejko, K. Safranow, P. Nowacki, B. Machaliński Tags: Original Articles Source Type: research

Deep cerebral microbleeds are negatively associated with HDL-C in elderly first-time ischemic stroke patients
Conclusions: Low HDL-C may be a risk factor of deep CMBs, including advanced PVH status, in elderly patients with acute ischemic stroke. Management of HDL-C levels might be a therapeutic target for the prevention of recurrence of stroke.
Source: Journal of the Neurological Sciences - January 14, 2013 Category: Neurology Authors: Michiya Igase, Katsuhiko Kohara, Keiji Igase, Shiro Yamashita, Mutsuo Fujisawa, Ryosuke Katagi, Tetsuro Miki Tags: Original Articles Source Type: research