The homocysteine associated variant rs548987 of SLC17A3 confers susceptibility to ischemic stroke in Chinese population

Ischemic stroke is a common cause of death due to obstructed blood supply of the brain. Despite growing numbers of research, etiology underlying ischemic stroke remains complex and elusive. Elevated plasma homocysteine has been known as a risk factor for ischemic stroke. Recently, a genome-wide association study reported association between rs548987 of SLC17A3 and homocysteine. Given existing relation between homocysteine and ischemic stroke, SLC17A3 was believed to be a promising candidate gene of ischemic stroke.

Source: Journal of the Neurological Sciences - August 17, 2016 Category: Neurology Authors: Shouqing Huang, Lianhua Yin, Yihui Xu, Chunyan Zou, Lidian Chen Source Type: research