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Source: Journal of the Neurological Sciences
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Total 856 results found since Jan 2013.
Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes due to m.3243A > G mutation in a 76-year-old woman
Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) with m.3243A > G mutation is a common type of mitochondrial disease [1,2]. Most patients with MELAS develop stroke-like episodes before the age of 40, a criterion of MELAS [3]. However, increasing reports have demonstrated that elderly subjects (≥ 60 years old) may develop this mitochondrial encephalopathy [4 ,5]. Here, we report a 76-year-old woman who was previously healthy without any organ dysfunction related to mitochondrial abnormalities (except for a mild hearing disability) and developed encephalopathy accompanied by stro...
Source: Journal of the Neurological Sciences - March 18, 2020 Category: Neurology Authors: Kana Ueki, Yoshinobu Wakisaka, Kuniyuki Nakamura, Yuji Shono, Shinichi Wada, Yoji Yoshikawa, Yuta Matsukuma, Takeshi Uchiumi, Dongchong Kang, Takanari Kitazono, Tetsuro Ago Tags: Letter to the Editor Source Type: research
Microstructural white matter changes following gait training with Hybrid Assistive Limb initiated within 1 week of stroke onset
The early initiation of robot-assisted gait training in patients with acute stroke could promote neuroplasticity. The aim of this study was to clarify the microstructural changes of white matter associated with gait training using Hybrid Assistive Limb (HAL) by diffusion tensor imaging (DTI). Patients with first-ever stroke and requiring a walking aid started gait training within 1 week of stroke onset. The patients were quasi-randomly assigned either to the conventional physical therapy (CPT) group or gait training using HAL (HAL) group.
Source: Journal of the Neurological Sciences - May 21, 2020 Category: Neurology Authors: Daisuke Ando, Chiaki Yokota, Kazuhiro Koshino, Fumihiko Yasuno, Takeo Sato, Akihide Yamamoto, Hirotaka Odani, Takashi Nakajima, Takahiro Higuchi, Eisuke Tatsumi Source Type: research
Prognostic role of the controlling nutritional status score in acute ischemic stroke among stroke subtypes
The association of malnutrition on stroke subtypes has not been well established. We investigated the relationship between malnutrition and functional outcome according to stroke subtypes.
Source: Journal of the Neurological Sciences - June 10, 2020 Category: Neurology Authors: Hiroyuki Naito, Naohisa Hosomi, Tomohisa Nezu, Daisuke Kuzume, Shiro Aoki, Yuko Morimoto, Takeshi Yoshida, Yuji Shiga, Naoto Kinoshita, Hiroki Ueno, Hirofumi Maruyama Source Type: research
Differentiation of seizure from stroke using advanced imaging in the acute period
Imaging modalities such as dynamic computed tomography (CT) studies of the brain have aided in clinical management of stroke patients through identification of tissue at risk and tissue infarcted. Such a capability provides the opportunity to intervene in stroke patients previously deemed unfit for thrombectomy, [1] while allowing software engineers to develop modeling tools stratifying the risk and benefit of intervention [2]. One unexpected consequence of these advances is the ability to recognize the neurophysiologic changes associated with stroke mimics such as seizure.
Source: Journal of the Neurological Sciences - August 31, 2020 Category: Neurology Authors: Merritt W. Brown Tags: Letter to the Editor Source Type: research
Acute ischemic stroke diagnosis using brain tissue pulsations
This study is the first to explore the clinical potential of measuring BTPs using ultrasound in acute ischemic stroke patients.BTPs were measured in 24 healthy volunteers (aged 52 –82 years) and 14 acute ischemic stroke patients (aged 51–86 years) using a novel Transcranial Tissue Doppler (TCTD) method. Measurements were quick to perform and were well tolerated by all subjects.
Source: Journal of the Neurological Sciences - October 2, 2020 Category: Neurology Authors: Jonathan Ince, Caroline Banahan, Sara Venturini, Meshal Alharbi, Poppy Turner, Mitsuhiro Oura, Kirk W. Beach, Thompson G. Robinson, Amit K. Mistri, Andrea Lecchini-Visintini, Jatinder S. Minhas, Emma M.L. Chung Source Type: research
Impact of pulmonary embolism on in-hospital mortality of patients with ischemic stroke
Pulmonary embolism (PE) is a frequent complication in immobile stroke patients and an important cause of death in stroke patients. We aimed to investigate predictors of PE and impact of PE on survival of ischemic stroke patients.
Source: Journal of the Neurological Sciences - October 8, 2020 Category: Neurology Authors: Karsten Keller, Lukas Hobohm, Thomas M ünzel, Mareike Lankeit, Mir Abolfazl Ostad Source Type: research
Effects of uncomfortable care and histamine H2-antagonists on delirium in acute stroke: A propensity score analysis
Uncomfortable care and histamine H2 antagonist (H2A) are implicated in precipitating delirium. In acute stroke, however, the need for them depends on stroke severity, an established risk factor for delirium. So, it is unclear whether care or H2A itself is responsible for delirium. We aimed to evaluate their causal effects on delirium in acute stroke patients.
Source: Journal of the Neurological Sciences - November 26, 2020 Category: Neurology Authors: Tomoki Nakamizo, Toshie Kanda, Yosuke Kudo, Eriko Sugawara, Erina Hashimoto, Ayana Okazaki, Makoto Usuda, Toru Nagai, Hiroshi Hara, Ken Johkura Source Type: research
Post-stroke dementia and permanent institutionalization
Dementia is among the most frequent causes of institutionalization. To serve the purpose of preventive strategies, there are no follow-up studies that have evaluated the actual impact of post-stroke dementia on institutionalization. We therefore compared the institutionalization rate and length of stay in an institutional care facility of patients with post-stroke dementia with stroke patients without dementia.
Source: Journal of the Neurological Sciences - January 2, 2021 Category: Neurology Authors: Gerli Sibolt, Sami Curtze, Hanna Jokinen, Tarja Pohjasvaara, Markku Kaste, Pekka J. Karhunen, Timo Erkinjuntti, Susanna Melkas, Niku K.J. Oksala Source Type: research
Trends in ischemic stroke outcomes in a rural population in the United States
The stroke mortality rate has gradually declined due to improved interventions and controlled risk factors. We investigated the trends in stroke recurrence and all-cause mortality in stroke patients from a rural population in the United States between 2004 and 2018.
Source: Journal of the Neurological Sciences - February 8, 2021 Category: Neurology Authors: Durgesh Chaudhary, Ayesha Khan, Shima Shahjouei, Mudit Gupta, Clare Lambert, Venkatesh Avula, Clemens M. Schirmer, Neil Holland, Christoph J. Griessenauer, M. Reza Azarpazhooh, Jiang Li, Vida Abedi, Ramin Zand Source Type: research
Are there disparities in acute stroke treatment between the Jewish and Arab populations in Israel? Results from the National Acute Stroke Israeli registry
According to the latest reported data from the National Acute Stroke Israeli Survey (NASIS), around 18,000 strokes occur annually in Israel. Data regarding disparities in stroke care between the Jewish and the Arab populations in Israel are lacking.
Source: Journal of the Neurological Sciences - February 19, 2021 Category: Neurology Authors: Naaem Simaan, Andrei Filioglo, Asaf Honig, Anat Horev, David Orion, Natan M. Bornstein, Gregory Telman, David Tanne, Guy Raphaeli, Jacob Amsalem, Jose E. Cohen, Neuman Hadar, Reem Habib-Simaan, Ronen R. Leker Source Type: research
Bedside video-oculographic evaluation of eye movements in acute supratentorial stroke patients: A potential biomarker for hemispatial neglect
In this study, we aimed to detect hemispatial neglect at the bedside in acute stroke patients by measuring eye movements using video-oculography (VOG).
Source: Journal of the Neurological Sciences - April 8, 2021 Category: Neurology Authors: Yosuke Kudo, Koji Takahashi, Eriko Sugawara, Tomoki Nakamizo, Miho Kuroki, Yuichi Higashiyama, Fumiaki Tanaka, Ken Johkura Source Type: research
Real-world analysis of botulinum toxin (BoNT) injections in post-stroke spasticity: Higher doses of BoNT and longer intervals in the early-start group
Our primary objective was to compare early-start vs. late-start Botulinum toxin (BoNT) injections in post-stroke spasticity management. This is an IRB approved retrospective chart review of patients who were admitted for inpatient rehabilitation within 6 months after first-ever stroke between January 2014 and December 2018 and received BoNT injections within 15 months. The total dose and interval between consecutive injections were used as objective outcomes. 2367 stroke admissions were reviewed.
Source: Journal of the Neurological Sciences - April 14, 2021 Category: Neurology Authors: Jean Woo, Manuel F. Mas, Juliana Zhang, Bonny Wong, Argyrios Stampas, Gerard E. Francisco, Sheng Li Source Type: research
Impact of revascularization therapies on outcome of posterior circulation ischemic stroke: The indo-US stroke project
Posterior circulation strokes (PCS) have been less extensively studied than anterior circulation strokes (ACS), especially regarding revascularization therapies. We analyzed the differences in baseline stroke characteristics, revascularization therapy and 3-month outcomes between PCS and ACS in a large prospective multicentre Indian stroke registry.
Source: Journal of the Neurological Sciences - May 18, 2021 Category: Neurology Authors: Sruthi S. Nair, P.N. Sylaja, Jeyaraj Pandian, M.V. Padma Srivastava, Dheeraj Khurana, Subhash Kaul, Deepti Arora, P. Sankara Sarma, Himani Khatter, Aneesh B. Singhal Source Type: research
Echocardiographic predictors of cardioembolic stroke due to underlying atrial fibrillation: Reliable left atrial remodeling signs in acute stroke
Atrial remodeling due to high-burden atrial fibrillation (AF) is associated with cardioembolic stroke (CES). As not all CESs is caused by AF, we analyzed the diagnostic values of each echocardiographic parameter to distinguish likely AF-related CES in acute stroke patients while in non-AF rhythm.
Source: Journal of the Neurological Sciences - May 31, 2021 Category: Neurology Authors: Keiko Shimamoto, Hideaki Kanzaki, Tomotaka Tanaka, Atsushi Hirayama, Masatoshi Koga, Kengo F. Kusano, Kazunori Toyoda, Satoshi Yasuda, Masafumi Ihara Source Type: research
Carotid webs in large vessel occlusion stroke: Clinical, radiological and thrombus histopathological findings
Carotid webs are an under-recognized embolic source in patients with cryptogenic stroke. Limited resources currently exist to assist clinicians in stroke prevention for patients with symptomatic carotid webs (SCW). We aimed at analysing the clinical, radiological and procedural features of stroke patients with SCW undergoing endovascular thrombectomy (EVT), and to describe the histopathological composition of their occlusive thrombi.
Source: Journal of the Neurological Sciences - June 21, 2021 Category: Neurology Authors: Aurora Semerano, Zakaria Mamadou, Jean Philippe Desilles, Candice Sabben, Marco Bacigaluppi, Michel Piotin, Mickael Mazighi, Lucas Di Meglio, Michael Obadia Tags: Clinical short communication Source Type: research
