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Source: Journal of the Neurological Sciences
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Total 856 results found since Jan 2013.
Pathological features of intracardiac bacterial vegetation and intracranial arterial thrombus due to infective endocarditis in a stroke patient
We report herein on autopsy and pathological findings for IE-related stroke in a patient receiving hemodialysis.
Source: Journal of the Neurological Sciences - October 17, 2014 Category: Neurology Authors: Takashi Shimoyama, Naoki Saji, Junichi Uemura, Kensaku Shibazaki, Hirotake Nishimura, Kazumi Kimura Tags: Letter to the Editor Source Type: research
Statin Use Increases the Risk of Depressive Disorder in Stroke Patients: A Population-Based Study
This study aimed to explore the risk for depressive disorder (DD) among stroke patients with statin use. Totally, 11,218 patients who had a first-time acute hospitalization for stroke were identified from Taiwan’s Longitudinal Health Insurance Database 2000. We individually followed each study subject for a 1-year period to identify those patients who were subsequently diagnosed with DD during the follow-up period. We found that the incidence rate of DD during the 1-year follow-up period was 5.52 (95% CI: 4.70~6.43) and 3.46 (95% CI: 3.08~3.88) per 100 person-years for stroke patients who were statin users and nonusers, respectively.
Source: Journal of the Neurological Sciences - November 17, 2014 Category: Neurology Authors: Jiunn-Horng Kang, Li-Ting Kao, Herng-Ching Lin, Ming-Chieh Tsai, Shiu-Dong Chung Source Type: research
Autonomic dysfunction in acute ischemic stroke: an underexplored therapeutic area?
Impaired autonomic function, characterized by a predominance of sympathetic activity, is common in patients with acute ischemic stroke. This review describes methods to measure autonomic dysfunction in stroke patients. It summarizes a potential relationship between ischemic stroke-associated autonomic dysfunction and factors that have been associated with worse outcome, including cardiac complications, blood pressure variability changes, hyperglycemia, immune depression, sleep disordered breathing, thrombotic effects, and malignant edema.
Source: Journal of the Neurological Sciences - December 8, 2014 Category: Neurology Authors: Sylvie De Raedt, Aurelie De Vos, Jacques De Keyser Source Type: research
The potential use of mesenchymal stem cells in stroke therapy - from bench to bedside
Stroke is the second main cause of morbidity and mortality worldwide. The rationale for the use of mesenchymal stem cells (MSCs) in stroke is based on the capacity of MSCs to secrete a large variety of bioactive molecules such as growth factors, cytokines and chemokines leading to reduction of inflammation, increased neurogenesis from the germinative niches of central nervous system, increased angiogenesis, effects on astrocytes, oligodendrocytes and axons. This review presents the data derived from experimental studies and the evidence available from clinical trials about the use of MSCs in stroke therapy.
Source: Journal of the Neurological Sciences - March 18, 2015 Category: Neurology Authors: Adriana Dulamea Tags: Review Article Source Type: research
Factors predicting post-stroke aphasia recovery
Aphasia is an important stroke sequel that impacts negatively on the HQoL of stroke patients. Although a number of stroke patients with aphasia will have good functional recovery, many are left with language deficits.
Source: Journal of the Neurological Sciences - March 21, 2015 Category: Neurology Authors: Musa Mamman Watila, Watila M.M., Balarabe S.A. Tags: Review article Source Type: research
The potential use of mesenchymal stem cells in stroke therapy—From bench to bedside
Stroke is the second main cause of morbidity and mortality worldwide. The rationale for the use of mesenchymal stem cells (MSCs) in stroke is based on the capacity of MSCs to secrete a large variety of bioactive molecules such as growth factors, cytokines and chemokines leading to reduction of inflammation, increased neurogenesis from the germinative niches of central nervous system, increased angiogenesis, effects on astrocytes, oligodendrocytes and axons. This review presents the data derived from experimental studies and the evidence available from clinical trials about the use of MSCs in stroke therapy.
Source: Journal of the Neurological Sciences - March 18, 2015 Category: Neurology Authors: Adriana Octaviana Dulamea Tags: Review Article Source Type: research
Is it safe to drive after acute mild stroke? A preliminary report
Most guidelines recommend that patients should refrain from driving for at least one month after stroke. Despite these guidelines, and the fact that patients post-stroke may be at an increased risk for driving impairment, many patients report resuming driving within the acute phase of injury. The aim of this study was to investigate the driving performance of patients with acute mild stroke.
Source: Journal of the Neurological Sciences - May 3, 2015 Category: Neurology Authors: Megan A. Hird, Kristin A. Vesely, Leah E. Christie, Melissa A. Alves, Jitphapa Pongmoragot, Gustavo Saposnik, Tom A. Schweizer Source Type: research
Permanent Reversal of Essential Tremor Following a frontal lobe stroke
Following a right prerolandic stroke, a 76year old woman with bilateral upper extremities essential tremor (ET) recovered permanently from the latter contralaterally to the affected hemisphere. The ischemic stroke likely interrupted the cortical component of the ET network. Given the magnitude of neuronal loss, post-stroke cortical reorganization was unable to restore this important component of the ET network, accounting for the permanent nature of ET suppression.
Source: Journal of the Neurological Sciences - May 9, 2015 Category: Neurology Authors: Moussa A. Chalah, Samar S. Ayache, Naji Riachi, Rechdi Ahdab Tags: Letter to the Editor Source Type: research
Left atrial dilatation is associated with severe ischemic stroke in men with non-valvular atrial fibrillation
and aim Increased left atrial volume is an independent predictive factor of first ischemic stroke and other cardiovascular events in patients with non-valvular atrial fibrillation (NVAF). However, correlations between left atrial dilatation and ischemic stroke severity or ischemic lesion pattern have not been previously reported. The aim of this study was to evaluate whether left atrial enlargement is associated with worse initial stroke severity and lesion patterns.
Source: Journal of the Neurological Sciences - May 13, 2015 Category: Neurology Authors: Tae-Won Kim, Sung-Woo Jung, In-Uk Song, Jaseong Koo, Hyun Seok Choi, Kwang-Soo Lee, Jeong-Wook Park, Hun-Jun Park, Joong-Seok Kim Source Type: research
Optimal Combination Treatment and Vascular Outcomes in Recent Ischemic Stroke Patients by Premorbid Risk Level
: Optimal combination of secondary stroke prevention treatment including antihypertensives, antithrombotic agents, and lipid modifiers is associated with reduced recurrent vascular risk including stroke. It is unclear whether optimal combination treatment has a differential impact on stroke patients based on level of vascular risk.
Source: Journal of the Neurological Sciences - May 28, 2015 Category: Neurology Authors: Jong-Ho Park, Bruce Ovbiagele Source Type: research
Temporal trends in vascular risk factors and etiology of urban Polish stroke patients from 1995 to 2013
Despite estimates about general trends in stroke epidemiology worldwide, there are only a few reports of detailed longitudinal data and none of them reflects the economic transition that occurred in Central and Eastern Europe over the last two decades. The aim of this study was to investigate long term trends in risk factors and their pre-stroke control as well as acute stroke clinical presentation and etiology in Polish urban setting.
Source: Journal of the Neurological Sciences - July 9, 2015 Category: Neurology Authors: Jan P. Bembenek, Michał Karlinski, Tadeusz A. Mendel, Maciej Niewada, Iwona Sarzynska-Dlugosz, Adam Kobayashi, Anna Baranowska, Anna Czlonkowska Source Type: research
Efficacy and Safety of NABOTA in Post-stroke Upper Limb Spasticity: A phase 3 multicenter, double-blinded, randomized controlled trial
Botulinum toxin A is widely used in the clinics to reduce spasticity and improve upper limb function for post-stroke patients. Efficacy and safety of a new botulinum toxin type A, NABOTA (DWP450) in post-stroke upper limb spasticity was evaluated in comparison with Botox (Onabotulinum toxin A). A total of 197 patients with post-stroke upper limb spasticity were included in this study and randomly assigned to NABOTA group (n=99) or Botox group (n=98). Wrist flexors with modified Ashworth Scale (MAS) grade 2 or greater, and elbow flexors, thumb flexors and finger flexors with MAS 1 or greater were injected with either drug.
Source: Journal of the Neurological Sciences - July 21, 2015 Category: Neurology Authors: Hyung Seok Nam, Yoon Ghil Park, Nam-Jong Paik, Byung-Mo Oh, Min Ho Chun, Hea-Eun Yang, Dae Hyun Kim, Youbin Yi, Han Gil Seo, Kwang Dong Kim, Min Cheol Chang, Jae Hak Ryu, Shi-Uk Lee Source Type: research
Trends in Stroke Admission and Mortality Rates from 1983 to 2013 in Central Ghana
Accumulating data based on model-derived estimates suggest rising rates of stroke in sub-Saharan Africa over the next several decades. Stroke is a leading cause of death, disability, and dementia worldwide. Directly enumerated hospital-based data on the longitudinal trajectory of stroke admissions and deaths in sub-Saharan Africa could help hospital administrators, public health officials, and government policy-makers with planning and utilization of scarce resources.
Source: Journal of the Neurological Sciences - August 3, 2015 Category: Neurology Authors: Fred S. Sarfo, John Akassi, Dominic Awuah, Sheila Adamu, Clara Nkyi, Mayowa Owolabi, Bruce Ovbiagele Source Type: research
Letter by Huang regarding article, ''Statin use increases the risk of depressive disorder in stroke patients: a population-based study''
We read with interest the article by Kang et al which evaluated the risk for depressive disorder (DD) among stroke patients with statin use [1]. In a retrospective cohort study including 11,218 Chinese patients who had a first-time acute hospitalization for stroke in Taiwan, the authors followed each study subject for a 1-year period, finding that regular statin use was positively associated with the occurrence of DD following stroke. Their findings seem interesting, but I would like to raise 2 concerns.
Source: Journal of the Neurological Sciences - August 14, 2015 Category: Neurology Authors: Jian Huang Source Type: research
Letter by Huang regarding the article, “Statin use increases the risk of depressive disorder in stroke patients: A population-based study”
I read with interest the article by Kang et al. which evaluated the risk for depressive disorder (DD) among stroke patients with statin use [1]. In a retrospective cohort study including 11,218 Chinese patients who had a first-time acute hospitalization for stroke in Taiwan, the authors followed each study subject for a 1-year period, finding that regular statin use was positively associated with the occurrence of DD following stroke. Their findings seem interesting, but I would like to raise 2 concerns.
Source: Journal of the Neurological Sciences - August 14, 2015 Category: Neurology Authors: Jian Huang Tags: Letter to the editor Source Type: research
