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Source: Journal of the Neurological Sciences

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Total 856 results found since Jan 2013.

The combination of heart rate variability and ABCD2 score portends adverse outcomes after minor stroke or transient ischemic attack
The residual recurrent risk of stroke, which cannot be entirely explained by the traditional ABCD2 score, still existed. Heart rate variability (HRV), a method for reflecting the function of automatic nervous system (ANS), was a novel predictor of secondary stroke events. We aimed to investigate the relationships of combined HRV and ABCD2 score with adverse outcomes after acute minor stroke (MS) or transient ischemic attack (TIA), and further investigate the independent associations between HRV and adverse outcomes after MS/TIA stratified by ABCD2 score.
Source: Journal of the Neurological Sciences - December 11, 2022 Category: Neurology Authors: Yu Tian, Yuesong Pan, Mengxing Wang, Xia Meng, Xingquan Zhao, Liping Liu, Yongjun Wang, Yilong Wang Source Type: research

Clinical features, risk factors and survival in cardiac myxoma-related ischemic stroke: A multicenter case-control study
Cardiac myxoma (CM) is an important etiology of stroke in young adults, but studies on CM-related ischemic stroke (CM-IS) are limited and conflicting. Hence, we investigated clinical characterizations, risk factors of CM-IS, and short-term survival after surgical resection.
Source: Journal of the Neurological Sciences - December 6, 2022 Category: Neurology Authors: Man-Li Qiao, Lin Ma, Chao-Bin Wang, Li-Bo Fang, Ze-Xin Fan, Tian-Tong Niu, Ze-Yi Wang, Jian-Feng Lu, Bo-Yi Yuan, Guang-Zhi Liu Source Type: research

Covid-19 associated free hanging clots in acute symptomatic carotid stenosis
Thrombotic complications including stroke were previously described following Covid-19. We aim to describe the clinical and radiological characteristics of Covid-19 related with acutely symptomatic carotid stenosis (aSCS).
Source: Journal of the Neurological Sciences - December 1, 2022 Category: Neurology Authors: Y. Schwartzmann, R.R. Leker, A. Filioglo, J. Molad, J.E. Cohen, A. Honig Tags: Clinical short communication Source Type: research

Role of bedside video-oculography in selecting neuroimaging in patients with acute vertigo and ataxia posterior fossa mass lesions
The acute vestibular syndrome ((AVS) is the sudden onset of continuous vertigo, nausea, vomiting and head motion intolerance [1]. The most common peripheral cause is a vestibular neuritis [2], and the most frequent central lesion associated with an AVS is an ischemic stroke in about 10 to 15% of cases [3 –5]; less frequently demyelinating plaques (multiple sclerosis (MS) and neuromyelitis optica (NMO)) [6], and inflammatory lesions associated with infectious and paraneoplastic disorders may be responsible.
Source: Journal of the Neurological Sciences - December 1, 2022 Category: Neurology Authors: Daniel Getz, Anusha Mangalampalli, Jeffrey Klopfenstein, Andrew Tsung, Jorge C. Kattah Source Type: research

Secondhand smoke exposure is independently associated with stroke among non-smoking adults in West Africa
Stroke is a leading cause of disability and mortality worldwide, but little is known about the contribution of secondhand smoke exposure (SHSE) to stroke epidemiology among indigenous Africans.
Source: Journal of the Neurological Sciences - November 8, 2022 Category: Neurology Authors: Akinkunmi Paul Okekunle, Osahon Jeffery Asowata, Adekunle G. Fakunle, Onoja Matthew Akpa, Fred S. Sarfo, Albert Akpalu, Kolawole Wahab, Reginald Obiako, Morenikeji Komolafe, Lukman Owolabi, Godwin O. Osaigbovo, Hemant K. Tiwari, Joshua Akinyemi, Carolyn J Tags: Clinical short communication Source Type: research

Use of dual antiplatelet therapy following posterior ischemic stroke
Patients with cerebral ischemia are at high-risk for early recurrent stroke, and use of short-term dual antiplatelet treatment (DAPT) for secondary prevention in high-risk TIA and minor stroke is recommended in current guidelines [1,2].
Source: Journal of the Neurological Sciences - November 1, 2022 Category: Neurology Authors: Letizia Maria Cupini, Novella Bonaffini Source Type: research

The human brain networks mediating the vestibular sensation of self-motion
Vestibular Agnosia - where peripheral vestibular activation triggers the usual reflex nystagmus response but with attenuated or no self-motion perception - is found in brain disease with disrupted cortical network functioning, e.g. traumatic brain injury (TBI) or neurodegeneration (Parkinson's Disease). Patients with acute focal hemispheric lesions (e.g. stroke) do not manifest vestibular agnosia. Thus, brain network mapping techniques, e.g. resting state functional MRI (rsfMRI), are needed to interrogate functional brain networks mediating vestibular agnosia.
Source: Journal of the Neurological Sciences - October 14, 2022 Category: Neurology Authors: Zaeem Hadi, Mohammad Mahmud, Yuscah Pondeca, Elena Calzolari, Mariya Chepisheva, Rebecca M. Smith, Heiko M. Rust, David J. Sharp, Barry M. Seemungal Source Type: research

Cilostazol-based dual anti-platelet agents for Asian patients: An updated network meta-analysis
Antiplatelet therapy, including aspirin, has been used for the secondary prevention of non-cardioembolic ischemic stroke [1]. Because patients who have a higher risk of recurrent stroke need antiplatelet agents with higher efficacy than aspirin, dual antiplatelet therapy (DAPT) has been used in cases requiring higher efficacy, such as the acute stage of stroke or high-risk patients [2]. However, DAPT is notably associated with an increased risk of bleeding like a two-edged sword [3]. Aspirin plus clopidogrel is recommended for a few weeks after acute ischemic stroke, preventing bleeding risk from not exceeding the power of...
Source: Journal of the Neurological Sciences - October 8, 2022 Category: Neurology Authors: Seung Jin Jung, Sung Ryul Shim, Bum Joon Kim, Jin-Man Jung Source Type: research

Dysarthria-facial paresis syndrome due to long insular artery infarction
Pure dysarthria-facial paresis is a rare stroke syndrome, primarily caused by lesions in the cortical or subcortical bulbar motor area, corona radiata, basal ganglia, internal capsule, and pons [1]. Corona Radiata is supplied by the lenticulostriate arteries (LSAs), long insular arteries (LIAs), and white matter medullary arteries (WMMAs); however, LSA infarctions are the most common [2]. We encountered four cases of dysarthria-facial paresis syndrome and found clear evidence of LIA and WMMA infarctions on coronal images.
Source: Journal of the Neurological Sciences - October 8, 2022 Category: Neurology Authors: Ryutaro Hanyu, Shintaro Tsuboguchi, Itaru Ninomiya, Takanobu Ishiguro, Takuya Konno, Masato Kanazawa, Osamu Onodera Source Type: research

Risk of readmission and mortality in patients with ischaemic stroke
Morton et al. conducted a 1-year follow-up study to evaluate the risk of readmission to hospital and all-cause mortality in patients with ischaemic stroke (IS) [1]. The cumulative incidence of all-cause readmission was 56.1%, and the adjusted hazard ratios (HRs) (95% confidence intervals [CI]) of patients with diabetes for all-cause, cardiovascular, and IS readmission were 1.13 (1.09 –1.17), 1.14 (1.07–1.21), and 1.17 (1.06–1.29). One-year mortality also increased significantly in patients with diabetes, and IS readmission and mortality were higher in women than those in men.
Source: Journal of the Neurological Sciences - September 30, 2022 Category: Neurology Authors: Tomoyuiki Kawada Source Type: research

An updated review and meta-analysis of screening tools for stroke in the emergency room and prehospital setting
Stroke screening tools should have good diagnostic performance for early diagnosis and a proper therapeutic plan. This paper describes and compares various diagnostic tools used to identify stroke in emergency departments and prehospital setting.
Source: Journal of the Neurological Sciences - September 26, 2022 Category: Neurology Authors: Durgesh Chaudhary, Johan Diaz, Yezhong Lu, Jiang Li, Vida Abedi, Ramin Zand Tags: Review Article Source Type: research

Prevalence of stroke in acute vertigo presentations: A UK tertiary stroke centre perspective
The reported prevalence of stroke amongst patients presenting to hospital with acute vertigo and/or imbalance is c. 5%, leading to the pervasive notion amongst emergency and stroke physicians, that stroke is uncommon in this cohort.To interrogate the veracity of this notion, we systematically and retrospectively screened the electronic care records in our institution of patients referred as suspected stroke, to a hyperacute stroke service at a large tertiary referral centre.We screened 24,310 consecutive patients' electronic case records presenting to our hospital as an emergency over a 4-month period, 332 of whom were ref...
Source: Journal of the Neurological Sciences - September 12, 2022 Category: Neurology Authors: Mohammad Mahmud, Abdel Rahman Saad, Zaeem Hadi, Jordan Elliot, Mabel Prendergast, Joseph Kwan, Barry Seemungal Source Type: research

Noninvasive cardiac output monitor to quantify hydration status in ischemic stroke patients: A feasibility study
Individuals who are dehydrated, volume contracted or both at the time of hospitalization for acute ischemic stroke have worse clinical outcomes than do individuals with optimal volume status. Currently, there is no gold standard method for measuring hydration status, except indirect markers of a volume contracted state (VCS) including elevated blood urea nitrogen (BUN)/creatinine ratio. We sought to test the feasibility and acceptability of a non-invasive cardiac output monitor (NICOM) for the measurement of hydration status in a group of hospitalized ischemic stroke patients, and explore the relationship with a common ind...
Source: Journal of the Neurological Sciences - September 8, 2022 Category: Neurology Authors: M.N. Bahouth, S. Negoita, A. Tenberg, E.K. Zink, M.A. Abshire, P.M. Davidson, J.I. Suarez, S. Szanton, R.F. Gottesman Source Type: research

Stroke in sickle cell disease and the promise of recent disease modifying agents
Sickle cell disease (SCD) is an inherited hemoglobinopathy affecting approximately 100,000 individuals in the United States. Cerebrovascular disease is among the most common and debilitating complications of SCA, with 53% experiencing silent cerebral infarct by age 30 and 3.8% experiencing overt stroke by age 40  years. This review highlights the burden of cerebrovascular disease in SCD, including both stroke and silent cerebral infarct (SCI). We then discuss the pathophysiology of stroke and cerebral fat embolism in the absence of a patent foramen ovale.
Source: Journal of the Neurological Sciences - September 8, 2022 Category: Neurology Authors: Ava Runge, Danielle Brazel, Zahra Pakbaz Tags: Review Article Source Type: research

The safety and efficacy of periprocedural intravenous anticoagulants for acute ischemic stroke patients who underwent endovascular treatment: Sub-analysis of the RESCUE-Japan Registry 2
The efficacy and safety of periprocedural anticoagulant therapy are still controversial. We investigated the effects of periprocedural anticoagulation on patients who underwent endovascular therapy (EVT) for acute ischemic stroke (AIS). The patients were dichotomized into two groups according to the use of intravenous anticoagulant during or within 24  h after EVT (AC or non-AC group). Primary outcome was defined as a modified Rankin Scale (mRS) score of 0–2 at 90 days. Safety outcomes were defined as any or symptomatic intracerebral hemorrhages (ICH).
Source: Journal of the Neurological Sciences - August 23, 2022 Category: Neurology Authors: Hirofumi Matsubara, Yukiko Enomoto, Egashira Yusuke, Kazutaka Uchida, Hiroshi Yamagami, Nobuyuki Sakai, Shinichi Yoshimura Source Type: research