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Source: Journal of the Neurological Sciences
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Total 856 results found since Jan 2013.
Comparison of automated infarct core volume measures between non-contrast computed tomography and perfusion imaging in acute stroke code patients evaluated for potential endovascular treatment
Patients with small core infarction and salvageable penumbra are likely to benefit from endovascular treatment (EVT). As computed tomography perfusion imaging (CTP) is not always available 24/7 for patient selection, many patients are transferred to stroke centers for CTP. We compared automatically measured infarct core volume (NCCTcore) from the non-contrast computed tomography (NCCT) with ischemic core volume (CTPcore) from CTP and the outcome of EVT to clarify if NCCTcore measurement alone is sufficient to identify patients that benefit from transfer to stroke centers for EVT.
Source: Journal of the Neurological Sciences - May 8, 2021 Category: Neurology Authors: Olli P. Suomalainen, Ahmed Abou Elseoud, Nicolas Martinez-Majander, Marjaana Tiainen, Nina Forss, Sami Curtze Source Type: research
Safety and efficacy of antiplatelet use before intravenous thrombolysis for acute Ischemic stroke
To study the effects of pretreatment with Antiplatelet (AP) before IV thrombolysis (IVT) on the rate of symptomatic intracranial hemorrhage (sICH) and functional outcome in patients with Acute Ischemic stroke (AIS).
Source: Journal of the Neurological Sciences - April 15, 2021 Category: Neurology Authors: Ashkan Mowla, Maryam Sharifian-Dorche, Sandhya Mehla, Navdeep S. Lail, Amirhossein Sharifian-Dorche, Caila B. Vaughn, Robert N. Sawyer, Peyman Shirani Source Type: research
Clopidogrel underactivity is a common in patients with acute symptomatic severe carotid stenosis
Clopidogrel is commonly used for secondary stroke prevention in patients with large vessel stenosis. Reduced Clopidogrel high on treatment platelet reactivity (CR) can lead to Clopidogrel underactivity (CU) causing acute thrombosis. However, the prevalence of CU among patients with acute symptomatic carotid disease remains unknown. Therefore, we aimed to find the prevalence and identify the predictors for CU among patients with acutely symptomatic carotid stenosis.
Source: Journal of the Neurological Sciences - April 14, 2021 Category: Neurology Authors: A. Honig, T. Sacagiu, A. Filioglo, N. Simaan, J. Kalish, J.M. Gomori, A. Horev, R.R. Leker, J.E. Cohen Tags: Clinical short communication Source Type: research
Real-world analysis of botulinum toxin (BoNT) injections in post-stroke spasticity: Higher doses of BoNT and longer intervals in the early-start group
Our primary objective was to compare early-start vs. late-start Botulinum toxin (BoNT) injections in post-stroke spasticity management. This is an IRB approved retrospective chart review of patients who were admitted for inpatient rehabilitation within 6 months after first-ever stroke between January 2014 and December 2018 and received BoNT injections within 15 months. The total dose and interval between consecutive injections were used as objective outcomes. 2367 stroke admissions were reviewed.
Source: Journal of the Neurological Sciences - April 14, 2021 Category: Neurology Authors: Jean Woo, Manuel F. Mas, Juliana Zhang, Bonny Wong, Argyrios Stampas, Gerard E. Francisco, Sheng Li Source Type: research
Stroke risk associated with carotid and aortic atherosclerosis in patients with atrial fibrillation: A systematic review
This review aimed to summarize the evidence on the risk of thromboembolism associated with carotid and aortic atherosclerosis in patients with AF, and the potential impact of their inclusion in current stroke risk stratification scores.
Source: Journal of the Neurological Sciences - April 10, 2021 Category: Neurology Authors: Jean Jacques Noubiap, Joseph Kamtchum-Tatuene, John L. Fitzgerald, Prashanthan Sanders Tags: Review Article Source Type: research
Bedside video-oculographic evaluation of eye movements in acute supratentorial stroke patients: A potential biomarker for hemispatial neglect
In this study, we aimed to detect hemispatial neglect at the bedside in acute stroke patients by measuring eye movements using video-oculography (VOG).
Source: Journal of the Neurological Sciences - April 8, 2021 Category: Neurology Authors: Yosuke Kudo, Koji Takahashi, Eriko Sugawara, Tomoki Nakamizo, Miho Kuroki, Yuichi Higashiyama, Fumiaki Tanaka, Ken Johkura Source Type: research
Diffusion weighted imaging in acute ischemic stroke: A review of its interpretation pitfalls and advanced diffusion imaging application
Diffusion weighted imaging (DWI) is a widely used imaging technique to evaluate patients with stroke. It can detect brain ischemia within minutes of stroke onset. However, DWI has few potential pitfalls that should be recognized during interpretation. DWI lesion could be reversible in the early hours of stroke and the entire lesion may not represent ischemic core. False negative DWI could lead to diagnosis of DWI negative stroke or to a missed stroke diagnosis. Ischemic stroke mimics can occur on DWI with non-cerebrovascular neurological conditions.
Source: Journal of the Neurological Sciences - April 3, 2021 Category: Neurology Authors: Nandakumar Nagaraja Tags: Review Article Source Type: research
Reply to the letter to the editor regarding “predictors and outcomes of hemorrhagic stroke in reversible cerebral vasoconstriction syndrome”
First, we thank the author of the letter for their interest and comments regarding our article [1]. Our study was focused on delineating the differential risk factors and clinical outcomes of hemorrhagic reversible cerebral vasoconstriction syndrome (RCVS). We found that intracranial hemorrhage was common among patients hospitalized due to RCVS and its occurrence was clearly associated with worse clinical outcomes.
Source: Journal of the Neurological Sciences - March 27, 2021 Category: Neurology Authors: Aayushi Garg, Santiago Ortega-Gutierrez Tags: Response to letter to the Editor Source Type: research
Re: Predictors and outcomes of hemorrhagic stroke in reversible cerebral vasoconstriction syndrome (Garg et al., Volume 421, 117312, February 15, 2021)
Dear Editor,
Source: Journal of the Neurological Sciences - March 27, 2021 Category: Neurology Authors: Aneesh B. Singhal Tags: Letter to the Editor Source Type: research
Assessment of vertical component of gaze deviation in acute PICA occlusion on Computed Tomography
In our recent article “Radiological Horizontal Gaze Deviation in the Setting of Acute PICA Territory Ischemia: A Potential Mimic of Large Vessel Occlusion”, we raised the possibility that the horizontal gaze deviation (HGD) seen in PICA stroke patients may be one component of rotational nystagmus [1]. PICA occlusion could result in vermis ischemia and thus, lead to disruption of pathway involving the deep cerebellar nuclei and stimulate fastigial neurons that is responsible saccade generation may fire result in oblique vertical saccades [2–4].
Source: Journal of the Neurological Sciences - March 24, 2021 Category: Neurology Authors: Nan N. Jiang, Wei Wu Source Type: research
Letter to the editor or commentary: Assessment of vertical component of gaze deviation in acute PICA occlusion on Computed Tomography
In our recent article “Radiological Horizontal Gaze Deviation in the Setting of Acute PICA Territory Ischemia: A Potential Mimic of Large Vessel Occlusion”, we raised the possibility that the horizontal gaze deviation (HGD) seen in PICA stroke patients may be one component of rotational nystagmus [1]. PICA occlusion could result in vermis ischemia and thus, lead to disruption of pathway involving the deep cerebellar nuclei and stimulate fastigial neurons that is responsible saccade generation may fire result in oblique vertical saccades [2–4].
Source: Journal of the Neurological Sciences - March 24, 2021 Category: Neurology Authors: Nan N. Jiang, Wei Wu Source Type: research
Adherence to anticoagulant guideline for atrial fibrillation: A large care gap among stroke patients in a rural population
This study aimed to investigate the prevalence and factors associated with oral anticoagulant undertreatment of atrial fibrillation (AF) among a cohort of rural patients with stroke outcomes and examine how undertreatment may influence a patient's one-year survival after stroke.
Source: Journal of the Neurological Sciences - March 20, 2021 Category: Neurology Authors: Johan Diaz, Eric Koza, Durgesh Chaudhary, Shima Shahjouei, Md Mobasshir Arshed Naved, Muhammad Taimur Malik, Jiang Li, Mohammad Adibuzzaman, Paul Griffin, Vida Abedi, Ramin Zand Source Type: research
Risk factors and outcomes of hospitalized stroke patients in Lusaka, Zambia
Limited data exists about stroke risk factors and outcomes in sub-Saharan African countries, including Zambia. We aim to fill this gap by describing features of hospitalized stroke patients at University Teaching Hospital (UTH), the national referral hospital in Lusaka, Zambia.
Source: Journal of the Neurological Sciences - March 18, 2021 Category: Neurology Authors: Aparna Nutakki, Mashina Chomba, Lorraine Chishimba, Stanley Zimba, Rebecca F. Gottesman, Mona N. Bahouth, Deanna Saylor Source Type: research
Atherosclerotic event risk and risk reduction therapies among Ghanaian hemorrhagic stroke survivors
Intracerebral hemorrhage (ICH) stroke constitute up to 40% of incident strokes in Africa. While ICH patients are at high risk for atherosclerotic events, the risk-benefit of anti-atherosclerotic therapies in this patient population is uncertain.
Source: Journal of the Neurological Sciences - March 9, 2021 Category: Neurology Authors: Fred Stephen Sarfo, Sheila Adamu, Vida Obese, Manolo Agbenorku, Priscilla Abrafi Opare-Addo, Bruce Ovbiagele Source Type: research
The neuropsychology needs of a hyper-acute stroke unit
Guidelines recommend routine assessment and management of mood and cognition after stroke, but little is known about the value or feasibility of providing neuropsychology input during the hyper-acute period. We aimed to identify and describe the extent and nature of neuropsychological needs and to investigate the feasibility of providing direct neuropsychology input within a hyper-acute setting.
Source: Journal of the Neurological Sciences - March 1, 2021 Category: Neurology Authors: Naomi H. Martin, Bronwyn Cornish, Simone Browning, Robert Simister, David J. Werring, Lisa Cipolotti, Edgar Chan Tags: Clinical short communication Source Type: research
