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Source: Journal of the Neurological Sciences
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Total 856 results found since Jan 2013.
Novel quantitative approach for crossed cerebellar diaschisis detection in acute ischemic stroke using CT perfusion
Crossed cerebellar diaschisis (CCD) is a common finding in hyper-acute ischemic stroke, related to supratentorial dysfunction of the contralateral hemisphere. Several studies investigated a possible relationship between CCD and clinical outcomes but still no evidence emerged. We used a novel quantitative whole cerebellum analysis using CT perfusion (CTP) imaging to investigate the relationship between CCD and stroke severity, hypoperfused volume and outcome measures.
Source: Journal of the Neurological Sciences - June 28, 2020 Category: Neurology Authors: Marcello Naccarato, Milo š Ajčević, Giovanni Furlanis, Carlo Lugnan, Alex Buoite Stella, Ilario Scali, Paola Caruso, Lara Stragapede, Maja Ukmar, Paolo Manganotti Source Type: research
Efficacy and safety of sonothrombolysis in patients with acute ischemic stroke: A systematic review and meta-analysis
Accumulating clinical evidence has indicated that sonothrombolysis can aid in the treatment of ischemic stroke; however, these findings remain controversial. The purpose of the present meta-analysis was to assess randomized clinical studies concerning the effects of sonothrombolysis on ischemic stroke to evaluate its safety and efficacy.
Source: Journal of the Neurological Sciences - June 24, 2020 Category: Neurology Authors: Xiaoqiang Li, Hui Du, Zhibin Song, Hui Wang, Zhijian Tan, Mufang Xiao, Fu Zhang Tags: Review Article Source Type: research
Clinical characteristics and brain MRI findings in myeloproliferative neoplasms
Myeloproliferative neoplasms (MPNs) including polycythemia vera (PV) and essential thrombocythemia (ET) have an increased risk of ischemic stroke. However, little is known about brain morphological changes and the cerebral vasculature in MPNs. The aim of the present study is to clarify the prevalence rates of brain infarcts (BIs) on magnetic resonance imaging (MRI) and to assess the detailed clinical and MRI characteristics in those patients.
Source: Journal of the Neurological Sciences - June 17, 2020 Category: Neurology Authors: Koichiro Nagai, Takashi Shimoyama, Hiroki Yamaguchi, Yuki Sakamoto, Satoshi Suda, Satoshi Wakita, Yasuhiro Nishiyama, Koiti Inokuchi, Kazumi Kimura Source Type: research
Risk of recurrent ischemic stroke in young cryptogenic patients with embolic stroke of undetermined source
Elderly cryptogenic ischemic stroke (IS) patients with embolic stroke of undetermined source (ESUS) have a high risk of recurrent IS (RIS) compared to other stroke subtypes. In young ESUS patients, different sources of embolism may be a cause and the risk of RIS remains not enough established. The aim was to assess and compare risk of RIS between ESUS and non ESUS patients
Source: Journal of the Neurological Sciences - June 11, 2020 Category: Neurology Authors: Daniel Šaňák, Petra Divišová, Martin Hutyra, Michal Král, Andrea Bártková, Jana Zapletalová, Jan Látal, Tomáš Dorňák, Štěpán Hudec, David Franc, Petr Polidar, Tomáš Veverka, Petr Kaňovský Source Type: research
Prognostic role of the controlling nutritional status score in acute ischemic stroke among stroke subtypes
The association of malnutrition on stroke subtypes has not been well established. We investigated the relationship between malnutrition and functional outcome according to stroke subtypes.
Source: Journal of the Neurological Sciences - June 10, 2020 Category: Neurology Authors: Hiroyuki Naito, Naohisa Hosomi, Tomohisa Nezu, Daisuke Kuzume, Shiro Aoki, Yuko Morimoto, Takeshi Yoshida, Yuji Shiga, Naoto Kinoshita, Hiroki Ueno, Hirofumi Maruyama Source Type: research
Frequency and factors linked to refractory hypertension among stroke survivors in Ghana
Refractory hypertension (RfH) is a rare, severe phenotype of resistant hypertension, linked to higher risk of adverse cardiovascular outcomes. Little is known about the association of RfH with stroke type and subtype.
Source: Journal of the Neurological Sciences - June 3, 2020 Category: Neurology Authors: Fred Stephen Sarfo, John Akassi, Sheila Adamu, Vida Obese, Manolo Agbenorku, Bruce Ovbiagele Source Type: research
Development of a clinical score, PANDA, to predict delirium in stroke care unit
Delirium frequently complicates acute stroke and worsens outcomes. Because delirium is potentially preventable, predicting its occurrence is essential. Although several prediction scores have been proposed, nurses need to quickly predict delirium in stroke care units (SCUs). We aimed to develop a simple tool for this purpose by examining a comprehensive set of potential predictors.
Source: Journal of the Neurological Sciences - May 29, 2020 Category: Neurology Authors: Tomoki Nakamizo, Toshie Kanda, Yosuke Kudo, Eriko Sugawara, Erina Hashimoto, Ayana Okazaki, Makoto Usuda, Toru Nagai, Hiroshi Hara, Ken Johkura Source Type: research
Sex influence in ischemic stroke severity and outcome among metabolically unhealthy overweight patients
The role of metabolically unhealthy (MU) overweight in influencing stroke prognosis has not been fully assessed and conclusive data about the impact of sex are lacking. Aim of this study was to evaluate the possible correlations among MU overweight, sex and ischemic stroke severity and outcome.
Source: Journal of the Neurological Sciences - May 29, 2020 Category: Neurology Authors: Giovanna Viticchi, Lorenzo Falsetti, Andrea Plutino, Marco Bartolini, Laura Buratti, Mauro Silvestrini Source Type: research
Assessment of the reporting quality of double-blind RCTs for ischemic stroke based on the CONSORT statement
It is critical that Randomized Controlled Trials(RCTs) present complete and transparent reporting. The present study aims to determine the reporting quality of double-blind RCTs for medicinal interventions in patients with ischemic stroke, based on the 2010 CONSORT-statement.
Source: Journal of the Neurological Sciences - May 26, 2020 Category: Neurology Authors: Michalis Kodounis, Ioannis N. Liampas, Theodoros S. Constantinidis, Vasileios Siokas, Alexios-Fotios A. Mentis, Athina-Maria Aloizou, Georgia Xiromerisiou, Elias Zintzaras, Georgios M. Hadjigeorgiou, Efthimios Dardiotis Source Type: research
Microstructural white matter changes following gait training with Hybrid Assistive Limb initiated within 1 week of stroke onset
The early initiation of robot-assisted gait training in patients with acute stroke could promote neuroplasticity. The aim of this study was to clarify the microstructural changes of white matter associated with gait training using Hybrid Assistive Limb (HAL) by diffusion tensor imaging (DTI). Patients with first-ever stroke and requiring a walking aid started gait training within 1 week of stroke onset. The patients were quasi-randomly assigned either to the conventional physical therapy (CPT) group or gait training using HAL (HAL) group.
Source: Journal of the Neurological Sciences - May 21, 2020 Category: Neurology Authors: Daisuke Ando, Chiaki Yokota, Kazuhiro Koshino, Fumihiko Yasuno, Takeo Sato, Akihide Yamamoto, Hirotaka Odani, Takashi Nakajima, Takahiro Higuchi, Eisuke Tatsumi Source Type: research
Teleneurology during the COVID-19 pandemic: A step forward in modernizing medical care
The COVID-19 pandemic mandated rapid transition from face-to-face encounters to teleneurology visits. While teleneurology is regularly used in acute stroke care, its application in other branches of neurology was limited. Here we review how the recent pandemic has created a paradigm shift in caring for patients with chronic neurological disorders and how academic institutions have responded to the present need.
Source: Journal of the Neurological Sciences - May 20, 2020 Category: Neurology Authors: Bhaskar Roy, Richard J. Nowak, Ricardo Roda, Babar Khokhar, Huned S. Patwa, Thomas Lloyd, Seward B. Rutkove Tags: Clinical short communication Source Type: research
Response to Letter regarding case report, “Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes due to m.3243A > G mutation in a 76-year-old woman ”
We appreciate Dr. Finsterer's comments [1] regarding our case report in which we described a previously healthy 76-year-old woman who developed non-convulsive status epilepticus (NCSE) as a stroke-like episode [2]. Her son, who had developed mitochondrial encephalopathy due to m.3243A > G at the age of 40 before her, presented with similar neurological symptoms and MRI findings. Using a quantitative digital PCR method, we detected 1.3% of the m.3243A > G mutation in mitochondrial DNA prepared from peripheral leukocytes in our case.
Source: Journal of the Neurological Sciences - May 18, 2020 Category: Neurology Authors: Tetsuro Ago, Kana Ueki, Yoshinobu Wakisaka, Kuniyuki Nakamura, Takanari Kitazono Tags: Response to letter to the Editor Source Type: research
Beyond the brain: Extra-axial pathology on diffusion weighted imaging in neuroimaging
Diffusion-weighted imaging (DWI) has a central role in the assessment of the brain parenchyma, particularly in the context of acute stroke. However, the applications of DWI extend far beyond the brain parenchyma and include the assessment of the extra-axial structures of the head and neck that are included in routine brain imaging.In this pictorial review, the added-value of DWI over other conventional sequences is illustrated through discussion of a broad range of disorders affecting the vasculature, skull, orbits, nasal cavity and salivary glands.
Source: Journal of the Neurological Sciences - May 18, 2020 Category: Neurology Authors: Dermot Mallon, Luke Dixon, Tom Campion, Gemma Dawe, Kunwar Bhatia, Carolina Kachramanaglou, Olga Kirmi Tags: Review Article Source Type: research
Expanding the cerebrovascular phenotype of the p.R258H variant in ACTA2 related hereditary thoracic aortic disease (HTAD)
Heterozygous variants in smooth muscle alpha-actin gene (ACTA2) are the most frequent cause of autosomal dominant hereditary thoracic aortic disease (HTAD). Several genotype-phenotype associations have been described, including a severe multisystemic smooth muscle disorder associated with de novo ACTA2 p.R179 variants, characterized by highly penetrant and early onset vascular disease, involvement of smooth muscle cell (SMC)-dependent organs and a distinct cerebrovascular phenotype. Missense variants at position 258 (p.R258C and p.R258H) have also been reported to have a more severe presentation including an increased risk...
Source: Journal of the Neurological Sciences - May 11, 2020 Category: Neurology Authors: Birgitte Rode Diness, Rachel Nina Palmquist, Rikke Norling, Hanne Hove, Henning Bundgaard, Jens Michael Hertz, Daniel Kondziella, Derk Krieger, Morten Dun ø, Sabine Grønborg Tags: Clinical Short Communication Source Type: research
Has COVID-19 played an unexpected “stroke” on the chain of survival?
The COVID-19 pandemics required several changes in stroke management and it may have influenced some clinical or functional characteristics. We aimed to evaluate the effects of the COVID-19 pandemics on stroke management during the first month of Italy lockdown. In addition, we described the emergency structured pathway adopted by an Italian University Hub Stroke Unit in the cross-border Italy-Slovenia area.
Source: Journal of the Neurological Sciences - May 5, 2020 Category: Neurology Authors: Marcello Naccarato, Ilario Scali, Sasha Olivo, Milos Aj čević, Alex Buoite Stella, Giovanni Furlanis, Carlo Lugnan, Paola Caruso, Alberto Peratoner, Franco Cominotto, Paolo Manganotti Tags: Clinical short communication Source Type: research
