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Source: Journal of the Neurological Sciences

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Total 856 results found since Jan 2013.

Quantitative CTA vascular calcification, atherosclerosis burden, and stroke mechanism in patients with ischemic stroke
Vascular calcification is recognized as the advanced stage of atherosclerosis burden. We hypothesized that vascular calcium quantification in CT angiography (CTA) would be helpful to differentiate large artery atherosclerosis (LAA) from other stroke etiology in patients with ischemic stroke.
Source: Journal of the Neurological Sciences - April 28, 2023 Category: Neurology Authors: Takashi Shimoyama, Sibaji Gaj, Kunio Nakamura, Shivakrishna Kovi, Shumei Man, Ken Uchino Source Type: research

The REMIT scale: A novel prediction scale for embolism in hyperacute stroke with large vessel occlusion
Large vessel occlusion (LVO) in hyperacute ischemic stroke occurs mainly by one of two mechanisms, embolism or atherosclerosis. However, the mechanism is difficult to identify prior to treatment. We aimed to investigate the factors associated with embolic LVO in hyperacute ischemic stroke, and to develop a preoperative predictive scale for the event.
Source: Journal of the Neurological Sciences - April 28, 2023 Category: Neurology Authors: Kenichi Sakuta, Takeo Sato, Ryoji Nakada, Tomomichi Kitagawa, Hiroki Takatsu, Michiyasu Fuga, Shinji Miyagawa, Teppei Komatsu, Kenichiro Sakai, Hidetaka Mitsumura, Hiroshi Yaguchi, Kenji Okuno, Toshihiro Ishibashi, Yuichi Murayama, Yasuyuki Iguchi Source Type: research

Pleocytosis in cerebrospinal fluid attributed to ischemic stroke: A review of the literature
Lumbar puncture is generally performed in stroke settings when infectious or inflammatory diseases are suspected to be the etiology. This review aimed to assess the prevalence of pleocytosis in the cerebrospinal fluid following ischemic stroke without inflammatory or infectious etiology.
Source: Journal of the Neurological Sciences - April 24, 2023 Category: Neurology Authors: Lucas Ivan Sebastian Rundblad, Helle K. Iversen, Anders S. West Tags: Review Article Source Type: research

Development of a stroke risk score with MRI asymptomatic brain lesions attributes to evaluate prognostic vascular events
The use of a combination of stroke predictors, such as clinical factors and asymptomatic lesions on brain magnetic resonance imaging (MRI), may improve the accuracy of stroke risk prediction. Therefore, we attempted to develop a stroke risk score for healthy individuals.
Source: Journal of the Neurological Sciences - April 2, 2023 Category: Neurology Authors: Kenichi Iwasa, Keiichi Onoda, Masahiro Takamura, Hiroyuki Takayoshi, Shingo Mitaki, Shuhei Yamaguchi, Atsushi Nagai Source Type: research

Mission thrombectomy 2020 (MT2020+) surveys of Caribbean stroke services: A call for action in our region
Stroke is the leading cause of death and adult-onset disability in the Caribbean region. Despite the tremendous advances in acute stroke care in the past 25  years, treatment in the Caribbean lags stroke standards of care. Mission Thrombectomy 2020+ (MT2020+) is a metrics based global campaign focused on increasing access to organized stroke care and mechanical thrombectomy.We conducted two consecutive online surveys across the MT2020+ Caribbean Regio n assessing access to thrombolytics, mechanical thrombectomy and stroke centers.
Source: Journal of the Neurological Sciences - March 31, 2023 Category: Neurology Authors: Gillian Gordon Perue, Ryna Then, Francene Gayle, Siddharth Galav, Yuvateja Thotamalla, Madihah Hepburn, Daidre Rowe, Luis Suazo, Cosme Villam án, Herbert Manosalva, Santiago Ortega-Gutierrez, Dileep Yavagal, Violiza Inoa, On behalf of MT2020+ Caribbean I Source Type: research

Participation by patients from low- and middle-income countries (LMICs) in trial evidence supporting secondary stroke prevention guideline recommendations
One out of every four strokes is a highly preventable recurrent stroke. However, while low-and-middle-income countries (LMICs) experience a disproportionate global burden of stroke, individuals in these regions seldomly participate in pivotal clinical trials, which form the basis for international expert consensus guideline recommendations.
Source: Journal of the Neurological Sciences - March 31, 2023 Category: Neurology Authors: Priscilla Abrafi Opare-Addo, Fred Stephen Sarfo, Patrick Opoku Berchie, Minas Aikins, Bruce Ovbiagele Tags: Review Article Source Type: research

Letter to editor: Is improved access to magnetic resonance imaging imperative for optimal ischemic stroke care?
We read the article “Is improved access to magnetic resonance imaging imperative for optimal ischemic stroke care?” [1] with great interest. The authors have presented a concise and informative summary of the use of MRI in ischemic stroke care, emphasizing its significance in diagnosis, management, and secondary pr evention. We appreciate the authors for presenting a comprehensive summary of the use of MRI in ischemic stroke care. However, we have certain points to make about the comparison of the MR scanners provided in this article.
Source: Journal of the Neurological Sciences - March 31, 2023 Category: Neurology Authors: Alex Panther Source Type: research

Computed tomography versus short sequence magnetic resonance imaging in acute ischaemic stroke
It is undisputable that the acute management of stroke requires a fast and accurate diagnostic imaging modality. We read with interest and congratulate Kumar et al. on their article discussing the superiority and benefits of the use of magnetic resonance imaging (MRI) in acute ischaemic stroke (AIS) [1]. The authors suggest that MRI can improve the diagnostic accuracy of computed tomography (CT) negative AIS and allow better selection of patients for reperfusion therapies. Moreover, MRI may help avoid hospital admissions for patients with stroke mimics, facilitate earlier discharge, reduce overall hospital costs and play a...
Source: Journal of the Neurological Sciences - March 30, 2023 Category: Neurology Authors: Ho Lun Wong, Ashraf Nasim, Amit K.J. Mandal, Robert Davies, Constantinos G. Missouris Source Type: research

Safety of recanalization therapy in patients with acute ischemic stroke on direct oral anticoagulants: A sub-analysis of PASTA registry study
The safety of intravenous recombinant tissue plasminogen activator (rtPA) and mechanical thrombectomy (MT) in patients treated with direct oral anticoagulants (DOACs) before stroke has not been fully investigated. Therefore, we aimed to investigate the safety of recanalization therapy in patients receiving DOACs.
Source: Journal of the Neurological Sciences - March 27, 2023 Category: Neurology Authors: Satoshi Suda, Arata Abe, Yasuyuki Iguchi, Yoshiki Yagita, Takao Kanzawa, Seiji Okubo, Shigeru Fujimoto, Yu Kono, Kazumi Kimura, on behalf of PASTA Investigators Source Type: research

Restricted access in the emergency department prevents MRI from being the workhorse for ischemic stroke care
We express our sincere gratitude to Wong et al. for their interest in our recent publication, “Is improved access to magnetic resonance imaging imperative for optimal ischemic stroke care?” [1]. We value the insights provided by the authors regarding the potential of magnetic resonance imaging (MRI) as the preferred imaging modality for acute ischemic stroke (AIS). Additionally, we appre ciate their valuable contribution on the utilization of short-sequence head MRI in addition to computed tomography (CT) for AIS evaluation at their center, which provides further evidence for the use of MRI in this context.
Source: Journal of the Neurological Sciences - March 26, 2023 Category: Neurology Authors: Mukesh Kumar, Sherry Hu, Steven Beyea, Noreen Kamal Source Type: research

Plasma growth differentiation factor  − 8 / Myostatin level as prognostic biomarker of patients with ischemic stroke and acute revascularization therapy. PARADISE study
This study aimed to assess the association between plasma Growth Differentiation Factor-8 (GDF-8)/Myostatin levels and outcome of IS patients.
Source: Journal of the Neurological Sciences - March 16, 2023 Category: Neurology Authors: Pauline Jakubina, Alexandre Meloux, Gauthier Duloquin, Serge Aho, Catherine Vergely, Yannick B éjot Source Type: research

Plasma growth differentiation factor  − 8 / Myostatin level as prognostic biomarker of patients with ischemic stroke and acute revascularization therapy. PARADISE study
This study aimed to assess the association between plasma Growth Differentiation Factor-8 (GDF-8)/Myostatin levels and outcome of IS patients.
Source: Journal of the Neurological Sciences - March 16, 2023 Category: Neurology Authors: Pauline Jakubina, Alexandre Meloux, Gauthier Duloquin, Serge Aho, Catherine Vergely, Yannick B éjot Source Type: research

Nonlinear relationship between pulse pressure and risk of cognitive impairment: A 4-year community-based cohort study in Xi'an, China
It has been known that pulse pressure (PP) is a risk factor for cardiovascular disease and stroke, however, the relationship between PP and cognitive impairment is unclear.
Source: Journal of the Neurological Sciences - March 10, 2023 Category: Neurology Authors: Rong Zhou, Yanyu Wang, Ling Gao, Liangjun Dang, Suhang Shang, Ningwei Hu, Wei Peng, Yi Zhao, Shan Wei, Ye Yuan, Fan Gao, Jin Wang, Qiumin Qu Source Type: research

Association of non-sustained atrial tachycardia and its duration in 24-h Holter monitoring with embolic stroke of unknown source
Although supraventricular ectopic beats (SVE), including premature atrial contractions (PACs) and non-sustained atrial tachycardia (NSAT), are frequent in the general population, some study results indicate that they are pathologic. SVE may predict undiagnosed atrial fibrillation or be associated with the embolic pattern of ischemic stroke. The aim of this study was to identify the indicators most associated with embolic stroke among the parameters that suggest the burden of SVE.
Source: Journal of the Neurological Sciences - March 4, 2023 Category: Neurology Authors: Yeonggeun Choi, Yerim Kim, Sung Eun Kim, Ju-Hun Lee Source Type: research

Neuroprotective effects of carnosine in a mice stroke model concerning oxidative stress and inflammatory response
In this study, we aimed to investigate the anti-oxidative, anti-inflammative, and anti-pyroptotic effects of carnosine in the transient middle cerebral artery occlusion (tMCAO) mouse model.
Source: Journal of the Neurological Sciences - March 3, 2023 Category: Neurology Authors: Xinran Hu, Yusuke Fukui, Tian Feng, Zhihong Bian, Haibo Yu, Ryuta Morihara, Xiao Hu, Yuting Bian, Hongming Sun, Mami Takemoto, Yumiko Nakano, Taijun Yunoki, Koji Abe, Toru Yamashita Source Type: research