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Source: Journal of the Neurological Sciences

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Total 856 results found since Jan 2013.

Delayed-onset motor aphasia succeeds Holmes' tremor and neuropathic pain after left thalamic hemorrhage
Although most neurological symptoms related to cerebrovascular diseases appear immediately after the events, some delayed-onset neurological symptoms, such as Holmes' tremor or central post-stroke pain (CPSP), can occur after a certain period of time [1]. The alterations in the neural networks caused by maladaptative neuroplasticity have been hypothesized to underlie this pathophysiology [2]. Here we report on a 53-year-old male patient who presented with a rare, delayed-onset motor aphasia caused by a left thalamic hemorrhage.
Source: Journal of the Neurological Sciences - February 23, 2021 Category: Neurology Authors: Tomoyo Shimada, Wataru Uchida, Atsuhiko Shindo, Koji Kamagata, Nobutaka Hattori, Taiji Tsunemi Tags: Letter to the Editor Source Type: research

Cerebral thrombi of cardioembolic etiology have an increased content of neutrophil extracellular traps
Inflammation is emerging as an essential trigger for thrombosis. In the interplay between innate immunity and coagulation cascade, neutrophils and neutrophil extracellular traps (NETs) can promote thrombus formation and stabilization. In ischemic stroke, it is uncertain whether the involvement of the inflammatory component may differ in thrombi of diverse etiology. We here aimed to evaluate the presence of neutrophils and NETs in thrombi of diverse etiology retrieved by endovascular thrombectomy (EVT).
Source: Journal of the Neurological Sciences - February 21, 2021 Category: Neurology Authors: Angela Genchi, Aurora Semerano, Giorgia Serena Gullotta, Davide Strambo, Ghil Schwarz, Andrea Bergamaschi, Pietro Panni, Franco Simionato, Francesco Scomazzoni, Caterina Michelozzi, Mattia Pozzato, Norma Maugeri, Giancarlo Comi, Andrea Falini, Luisa Rover Source Type: research

Are there disparities in acute stroke treatment between the Jewish and Arab populations in Israel? Results from the National Acute Stroke Israeli registry
According to the latest reported data from the National Acute Stroke Israeli Survey (NASIS), around 18,000 strokes occur annually in Israel. Data regarding disparities in stroke care between the Jewish and the Arab populations in Israel are lacking.
Source: Journal of the Neurological Sciences - February 19, 2021 Category: Neurology Authors: Naaem Simaan, Andrei Filioglo, Asaf Honig, Anat Horev, David Orion, Natan M. Bornstein, Gregory Telman, David Tanne, Guy Raphaeli, Jacob Amsalem, Jose E. Cohen, Neuman Hadar, Reem Habib-Simaan, Ronen R. Leker Source Type: research

Significance of concurrent ipsilateral intracranial carotid artery stenosis in carotid revascularization
A 71-year-old male presenting with a transient ischemic attack was found to have an ipsilateral severe proximal right internal carotid artery (ICA) stenosis as graded per the North American Symptomatic Carotid Endarterectomy Trial (NASCET) criteria. He was subsequently treated with right internal carotid endarterectomy (CEA). The surgery was complicated by a right sided watershed infarction determined by magnetic resonance imaging (MRI) of the head. His post-surgery National Institutes of Health Stroke Scale score was 6 and the 90  days modified Rankin Scale score was 3.
Source: Journal of the Neurological Sciences - February 19, 2021 Category: Neurology Authors: Riwaj Bhagat, Allison Muha Tags: Letter to the Editor Source Type: research

Characteristics and outcomes of 100 consecutive patients with acute stroke and COVID-19
The coronavirus disease 2019 (COVID-19) pandemic started as a respiratory illness. Now, there are increasing reports of its hypercoagulable and thrombotic complications [1] leading to stroke [2,3]. Initial studies suggested strokes to be a feature of severe and late COVID-19 [2,4]; usually occurring in the second week of illness after the onset of typical respiratory symptoms [4]. Recent studies identified these even in mild to moderate infection [5,6]. A recent meta-analysis also noted that 24.5% of patients with stroke symptoms did not experience any of the other typical COVID- 19 symptoms [6].
Source: Journal of the Neurological Sciences - February 16, 2021 Category: Neurology Authors: Rajesh Benny, Rakeshsingh K. Singh, Anil Venkitachalam, Rakesh Shyam Lalla, Rahul A. Pandit, Keyur C. Panchal, Vibhor Pardasani, Gunjan Chanchalani, Mheboob Basle, Vyankatesh Bolegave, Hunnur Manoj, Ashutosh N. Shetty, Amit M. Shah, Pawan Pai, Nilesh M. B Source Type: research

Trends in ischemic stroke outcomes in a rural population in the United States
The stroke mortality rate has gradually declined due to improved interventions and controlled risk factors. We investigated the trends in stroke recurrence and all-cause mortality in stroke patients from a rural population in the United States between 2004 and 2018.
Source: Journal of the Neurological Sciences - February 8, 2021 Category: Neurology Authors: Durgesh Chaudhary, Ayesha Khan, Shima Shahjouei, Mudit Gupta, Clare Lambert, Venkatesh Avula, Clemens M. Schirmer, Neil Holland, Christoph J. Griessenauer, M. Reza Azarpazhooh, Jiang Li, Vida Abedi, Ramin Zand Source Type: research

Predictors and outcomes of hemorrhagic stroke in reversible cerebral vasoconstriction syndrome
In this study, we compared hemorrhagic and non-hemorrhagic RCVS with an aim to evaluate the risk factors and short-term clinical outcomes of hemorrhagic lesions.
Source: Journal of the Neurological Sciences - January 7, 2021 Category: Neurology Authors: Aayushi Garg, Marcelo Rocha, Matthew Starr, Santiago Ortega-Gutierrez Source Type: research

Post-stroke dementia and permanent institutionalization
Dementia is among the most frequent causes of institutionalization. To serve the purpose of preventive strategies, there are no follow-up studies that have evaluated the actual impact of post-stroke dementia on institutionalization. We therefore compared the institutionalization rate and length of stay in an institutional care facility of patients with post-stroke dementia with stroke patients without dementia.
Source: Journal of the Neurological Sciences - January 2, 2021 Category: Neurology Authors: Gerli Sibolt, Sami Curtze, Hanna Jokinen, Tarja Pohjasvaara, Markku Kaste, Pekka J. Karhunen, Timo Erkinjuntti, Susanna Melkas, Niku K.J. Oksala Source Type: research

Physical restraint precipitates delirium in stroke patients
In this issue of Journal of the Neurological Sciences, an interesting paper by Nakamizo and colleagues analyses causative effect of uncomfortable care on delirium onset in stroke patients [1].
Source: Journal of the Neurological Sciences - December 20, 2020 Category: Neurology Authors: Eleonora Rollo, Antonio Callea, Valerio Brunetti, Catello Vollono, Jessica Marotta, Giacomo Della Marca Tags: Editorial Source Type: research

Risk profile of decompressive hemicraniectomy for malignant stroke after revascularization treatment
Revascularization by pharmacological and/or endovascular treatment is an effective therapy for acute ischemic stroke caused by artery occlusion. In the context of malignant middle cerebral artery infarction (MMI), decompressive hemicraniectomy (DHC) can be life-saving. However, its effectiveness and safety after revascularization have not been thoroughly assessed. This retrospective study aimed to determine the risk profile of pre-surgical revascularization treatment (RT) for subsequent DHC.
Source: Journal of the Neurological Sciences - December 16, 2020 Category: Neurology Authors: Mohamed Alzayiani, Tobias Schmidt, Michael Veldeman, Alexander Riabikin, Marc A. Brockmann, Johannes Schiefer, Hans Clusmann, Gerrit A. Schubert, Walid Albanna Source Type: research

Neural substrates of subcortical aphasia in subacute stroke: Voxel-based lesion symptom mapping study
Subcortical aphasia develops as a result of damage to subcortical brain areas without loss of cortical functions. Although earlier voxel-based lesion-symptom mapping (VLSM) studies have shown possible neural correlates for aphasia, it remains to be clarified which brain regions are associated with subcortical aphasia. The aim of this study was to investigate the neural substrates associated with subcortical aphasia in patients with stroke using VLSM and atlas-based analyses to explore the involvement of white matter tracts and subcortical structures.
Source: Journal of the Neurological Sciences - December 9, 2020 Category: Neurology Authors: Gowun Kim, ByeongChang Jeong, Myungwon Choi, Won-Seok Kim, Cheol E. Han, Nam-Jong Paik Source Type: research

Laboratory factors associated with symptomatic hemorrhagic conversion of acute stroke after systemic thrombolysis
This study aimed to investigate the laboratory factors predisposing to HC in AIS patients receiving IVT.
Source: Journal of the Neurological Sciences - December 9, 2020 Category: Neurology Authors: Haris Kamal, Bijal K. Mehta, M. Khaleeq Ahmed, Katelyn S. Kavak, Alicia Zha, Navdeep S. Lail, Peyman Shirani, Fawaz Al-Mufti, Robert N. Sawyer, Ashkan Mowla Source Type: research

Age differences in utilization and outcomes of tissue-plasminogen activator and mechanical thrombectomy in acute ischemic stroke
The objective of this study is to evaluate extent of difference in utilization of t-PA and MT and outcomes of stroke between three age groups −18–45 (young adults), 46–80 (middle/old), and > 80 (oldest old) years.
Source: Journal of the Neurological Sciences - December 7, 2020 Category: Neurology Authors: Nandakumar Nagaraja, Urvish K. Patel, Seemant Chaturvedi Source Type: research

Early-hospital readmission after generalized status epilepticus during stroke hospitalization
To assess the relationship between generalized convulsive status epilepticus (GCSE) during an index stroke hospitalization and occurrence of 30-day hospital readmission.
Source: Journal of the Neurological Sciences - November 30, 2020 Category: Neurology Authors: Alain Lekoubou, Kinfe G. Bishu, Bruce Ovbiagele Source Type: research

Psychostimulant use disorder emphasizing methamphetamine and the opioid -dopamine connection: Digging out of a hypodopaminergic ditch
Approved food and drug administration (FDA) medications to treat Psychostimulant Use Disorder (PUD) are needed. Both acute and chronic neurological deficits related to the neurophysiological effects of these powerfully addictive drugs can cause stroke and alterations in mood and cognition.
Source: Journal of the Neurological Sciences - November 27, 2020 Category: Neurology Authors: Kenneth Blum, Jean Lud Cadet, Mark S. Gold Tags: Review Article Source Type: research