Neural substrates of subcortical aphasia in subacute stroke: Voxel-based lesion symptom mapping study

Subcortical aphasia develops as a result of damage to subcortical brain areas without loss of cortical functions. Although earlier voxel-based lesion-symptom mapping (VLSM) studies have shown possible neural correlates for aphasia, it remains to be clarified which brain regions are associated with subcortical aphasia. The aim of this study was to investigate the neural substrates associated with subcortical aphasia in patients with stroke using VLSM and atlas-based analyses to explore the involvement of white matter tracts and subcortical structures.

Source: Journal of the Neurological Sciences - December 9, 2020 Category: Neurology Authors: Gowun Kim, ByeongChang Jeong, Myungwon Choi, Won-Seok Kim, Cheol E. Han, Nam-Jong Paik Source Type: research