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Source: Journal of the Neurological Sciences
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Total 856 results found since Jan 2013.
Covert COVID-19 complications: Continuing the use of evidence-based drugs to minimize potentially lethal indirect effects of the pandemic in stroke patients
Stroke and cardiovascular diseases are the world's biggest killers, globally accounting for over 15 million deaths each year (https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death). Since the Coronavirus Disease 2019 (COVID-19) outbreak in Wuhan, China and its rapid spread to other countries, as of April 272,020, there were about 3 million cases with over 190,000 deaths worldwide. However, actual situation might be even more dire, since such statistics likely do not fully display the entire impact of COVID-19, especially with regard to its influence on patients with a history of stroke who need to tak...
Source: Journal of the Neurological Sciences - May 5, 2020 Category: Neurology Authors: Meng Lee, Chi-Hsin Sally Chen, Bruce Ovbiagele Tags: Letter to the Editor Source Type: research
Cerebral vascular reactivity and the migraine-stroke relationship: A narrative review
Migraine, and especially migraine with aura, is associated with an increased risk of stroke and vascular events; however, the reasons for this association are unclear. Several studies evaluated cerebral autoregulation and vasomotor reactivity in patients with migraine compared with non-migraineurs, with conflicting results. Our narrative review aimed at summarizing their results to find the most reliable evidence in the field. Studies which used visual stimuli to evoke vascular responses consistently showed an increased vascular reactivity in migraineurs compared with non-migraineurs, while studies which used systemic stim...
Source: Journal of the Neurological Sciences - May 4, 2020 Category: Neurology Authors: Raffaele Ornello, Ilaria Frattale, Valeria Caponnetto, Francesca Pistoia, Simona Sacco Tags: Review Article Source Type: research
Impact of complete recanalization on clinical recovery in cardioembolic stroke patients with M2 occlusion
We investigated the impact of complete recanalization beyond partial recanalization in distal (M2) middle cerebral artery (MCA) occlusion.
Source: Journal of the Neurological Sciences - May 2, 2020 Category: Neurology Authors: Junya Aoki, Kentaro Suzuki, Takuya Kanamaru, Takehiro Katano, Akihito Kutsuna, Yuki Sakamoto, Satoshi Suda, Yasuhiro Nishiyama, Naomi Morita, Masafumi Harada, Shinji Nagahiro, Kazumi Kimura Source Type: research
Elevated cardio-ankle vascular index may be related to future stroke risk in Japanese subjects
The cardio-ankle vascular index (CAVI) has been proposed as a useful parameter for arteriosclerotic diseases. However, whether it is associated with stroke risk in Japanese subjects remains unclear.
Source: Journal of the Neurological Sciences - April 27, 2020 Category: Neurology Authors: Yasuhiro Nishiyama, Toshiaki Otsuka, Kanako Muraga, Katsuhito Kato, Yoshiyuki Saiki, Hiroshi Nagayama, Kazumi Kimura Source Type: research
Evaluation of oxidative stress-related genetic variants for predicting stroke in patients with sickle cell anemia
Overt stroke in adults with sickle cell anemia (SCA) continues to be a major cause of morbidity and mortality, while no evidence-based strategy for prevention has been reached so far. Although transcranial Doppler ultrasonography represents the most important tool for identifying young patients with SCA at risk of primary stroke, strategies for stroke prediction in adulthood remain challenging. Emerging data suggest that oxidative stress may exert a pivotal role in the pathogenesis of ischemic brain injury.
Source: Journal of the Neurological Sciences - April 15, 2020 Category: Neurology Authors: Igor F. Domingos, Diego A. Pereira-Martins, Rayssa L. Borges-Medeiros, Diego A. Falcao, Betania L. Hatzlhofer, John N. Brewin, Kate Gardner, Taciana F. Mendonca, Maria S. Cavalcanti, Anderson F. Cunha, Ana C. Anjos, Evandra S. Rodrigues, Simone Kashima, P Source Type: research
Prevalence and predictors of statin utilization among patient populations at high vascular risk in Ghana
Inadequate implementation of evidence-based preventive measures for individuals at high risk of cardiovascular disease (CVD) will only worsen the current epidemic of CVDs in sub-Saharan Africa. We assessed rates and predictors of statin utilization among two high CVD risk patient populations, people with type 2 diabetes mellitus (T2DM) and those with stroke, encountered across five hospitals in Ghana.
Source: Journal of the Neurological Sciences - April 14, 2020 Category: Neurology Authors: Fred Stephen Sarfo, Bruce Ovbiagele Source Type: research
Diagnostic value of N-terminal pro B-type natriuretic peptide for nonvalvular atrial fibrillation in acute ischemic stroke patients: A retrospective multicenter case-control study
The objective of this study is to evaluate the N-terminal pro B-type natriuretic peptide (NT-proBNP) diagnostic value for NVAF and the clinical outcome of AIS patients.
Source: Journal of the Neurological Sciences - April 5, 2020 Category: Neurology Authors: Jingjing Zhao, Yi Zhang, Fang Yuan, Changgeng Song, Yongli Jiang, Qiong Gao, Xiuxiu Leng, Wen Jiang Source Type: research
Paradoxical embolism through a patent foramen ovale from central venous catheter thrombosis: A potential cause of stroke
Paradoxical embolism refers to a potential condition in which an embolus arising from a venous source crosses into the systemic circulation through a right-to-left cardiac shunt causing an arterial embolism.A 39-year-old woman carrier of a central venous catheter (CVC) without evident risk factors for stroke, developed an acute right homonymous hemianopia during hemodialysis. On neuroimaging, an infarct in the territory of the left posterior cerebral artery was demonstrated. Transesophageal echocardiography revealed a patent foramen ovale (PFO) and a large fluctuating thrombus in the right atrium on the tip of the CVC, thu...
Source: Journal of the Neurological Sciences - April 3, 2020 Category: Neurology Authors: Di Stefano Vincenzo, Di Fulvio Maria, Di Liberato Lorenzo, Onofrj Marco, De Angelis Maria Vittoria Tags: Clinical Short Communication Source Type: research
An Italian family carrying a new mutation in the COL4A1 gene
Cerebral small vessel disease (SVD) is a group of pathologies affecting small arteries, arterioles, capillaries and small veins in the brain [1]. Neurological findings include cognitive impairment, dysfunction of gait and balance, mood disorders, increased risk of stroke and dementia. Cerebral SVD is driven by a complex mix of environmental and genetic risk factors; both familial and sporadic conditions have been reported [2]. Mutations in the NOTCH3, HTRA1, COL4A1, COL4A2 and TREX1A genes are known to cause the familial forms of SVD [2].
Source: Journal of the Neurological Sciences - March 30, 2020 Category: Neurology Authors: A. Russo, A.M. Pinto, D. Lopergolo, A. Renieri, C. Battisti Tags: Letter to the Editor Source Type: research
D-dimer level and outcome of minor ischemic stroke with large vessel occlusion
To determine the predictors of unfavorable outcomes in acute minor ischemic stroke patients with large vessel occlusion.
Source: Journal of the Neurological Sciences - March 30, 2020 Category: Neurology Authors: Takeo Sato, Shoichiro Sato, Hiroshi Yamagami, Teppei Komatsu, Tadataka Mizoguchi, Takeshi Yoshimoto, Masahito Takagi, Masafumi Ihara, Masatoshi Koga, Hiroyoshi Iwata, Masato Matsushima, Kazunori Toyoda, Yasuyuki Iguchi Source Type: research
Stroke and HIV in Botswana: A prospective study of risk factors and outcomes
HIV is associated with an increased risk of stroke, but there are sparse data on risk factors for stroke in people living with HIV in Sub-Saharan African. The goal of this study was to identify HIV-specific stroke characteristics and risk factors among adults in Botswana.
Source: Journal of the Neurological Sciences - March 25, 2020 Category: Neurology Authors: David R. Bearden, Bernard Omech, Ikanyeng Rulaganyang, Sheikh O. Sesay, Dennis L. Kolson, Scott E. Kasner, Michael T. Mullen Source Type: research
Asymptomatic carotid intraplaque hemorrhage is associated with a high risk of cerebral infarction and death after cardiovascular surgery
There is a lack of information on the natural history of asymptomatic carotid artery stenosis (AsymCS) associated with cardiovascular diseases that require surgery. The aim of this study was to investigate risk factors for postoperative ipsilateral ischemic stroke and all-cause mortality after cardiovascular surgery in patients with AsymCS.
Source: Journal of the Neurological Sciences - March 25, 2020 Category: Neurology Authors: Kouichi Misaki, Takehiro Uno, Iku Nambu, Ryouken Kimura, Akifumi Yoshikawa, Tomoya Kamide, Yasuhiko Hayashi, Naoyuki Uchiyama, Kenji Iino, Hirofumi Takemura, Mitsutoshi Nakada Source Type: research
Cilostazol uncovers covert atrial fibrillation in non-cardioembolic stroke
We hypothesized that administration of cilostazol may clarify the occult atrial fibrillation (AF) during hospitalization in mild stroke patients, who has no history of AF.
Source: Journal of the Neurological Sciences - March 20, 2020 Category: Neurology Authors: Junya Aoki, Yasuyuki Iguchi, Takao Urabe, Hiroshi Yamagami, Kenichi Todo, Shigeru Fujimoto, Koji Idomari, Nobuyuki Kaneko, Takeshi Iwanaga, Tadashi Terasaki, Ryota Tanaka, Nobuaki Yamamoto, Akira Tsujino, Koichi Nomura, Koji Abe, Masaaki Uno, Yasushi Okad Source Type: research
Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes due to m.3243A > G mutation in a 76-year-old woman
Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) with m.3243A > G mutation is a common type of mitochondrial disease [1,2]. Most patients with MELAS develop stroke-like episodes before the age of 40, a criterion of MELAS [3]. However, increasing reports have demonstrated that elderly subjects (≥ 60 years old) may develop this mitochondrial encephalopathy [4 ,5]. Here, we report a 76-year-old woman who was previously healthy without any organ dysfunction related to mitochondrial abnormalities (except for a mild hearing disability) and developed encephalopathy accompanied by stro...
Source: Journal of the Neurological Sciences - March 18, 2020 Category: Neurology Authors: Kana Ueki, Yoshinobu Wakisaka, Kuniyuki Nakamura, Yuji Shono, Shinichi Wada, Yoji Yoshikawa, Yuta Matsukuma, Takeshi Uchiumi, Dongchong Kang, Takanari Kitazono, Tetsuro Ago Tags: Letter to the Editor Source Type: research
Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes due to m.3243A > G mutation in a 76-year-old woman
Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) with m.3243A > G mutation is a common type of mitochondrial disease [1,2]. Most patients with MELAS develop stroke-like episodes before the age of 40, a criterion of MELAS [3]. However, increasing reports have demonstrated that elderly subjects (≥ 60 years old) may develop this mitochondrial encephalopathy [4,5]. Here, we report a 76-year-old woman who was previously healthy without any organ dysfunction related to mitochondrial abnormalities (except for a mild hearing disability) and developed encephalopathy accompanied by st...
Source: Journal of the Neurological Sciences - March 18, 2020 Category: Neurology Authors: Kana Ueki, Yoshinobu Wakisaka, Kuniyuki Nakamura, Yuji Shono, Shinichi Wada, Yoji Yoshikawa, Yuta Matsukuma, Takeshi Uchiumi, Dongchong Kang, Takanari Kitazono, Tetsuro Ago Tags: Letter to the Editor Source Type: research
