Comparative efficacy and safety of tenecteplase and alteplase in acute ischemic stroke: A pairwise and network meta-analysis of randomized controlled trials

Studies on tenecteplase have been yielding mixed results on several important variables at different doses, thus hampering objective guideline recommendations in acute ischemic stroke management. This meta-analysis stratifies doses in order to refine our interpretation of outcomes and quantify the benefits and harms of tenecteplase at different doses.

Source: Journal of the Neurological Sciences - December 28, 2022 Category: Neurology Authors: Aqeeb Ur Rehman, Aleenah Mohsin, Huzaifa Ahmad Cheema, Afra Zahid, Muhammad Ebaad Ur Rehman, Muhammad Zain Ameer, Muhammad Ayyan, Muhammad Ehsan, Abia Shahid, Muhammad Aemaz Ur Rehman, Jaffer Shah, Ayaz Khawaja Tags: Review Article Source Type: research