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Chocolate intake in pre-menopausal women
We thank Dr. Mattioli and Dr. Farinetti for their letter regarding our article “Chocolate consumption and risk of stroke among men and women: A large population-based, prospective cohort study” [1]. We are delighted that they are interested in the paper and think our finding is of importance with a view on stroke prevention.
Source: Atherosclerosis - December 19, 2017 Category: Cardiology Authors: Jia-Yi Dong, Hiroyasu Iso Tags: Correspondence Source Type: research

Reply to: “Chocolate intake in pre-menopausal women”
We thank Dr. Mattioli and Dr. Farinetti for their letter regarding our article “Chocolate consumption and risk of stroke among men and women: A large population-based, prospective cohort study” [1]. We are delighted that they are interested in the paper and think our finding is of importance, with a view on stroke prevention.
Source: Atherosclerosis - December 19, 2017 Category: Cardiology Authors: Jia-Yi Dong, Hiroyasu Iso Tags: Correspondence Source Type: research

Renal function is associated with 1-month and 1-year mortality in patients with ischemic stroke
This study aimed to evaluate the impact of admission estimated glomerular filtration rate (eGFR) levels on short-term (1-month) and long-term (1-year) mortality in patients with acute ischemic stroke.
Source: Atherosclerosis - December 11, 2017 Category: Cardiology Authors: I-Kuan Wang, Chung-Hsiang Liu, Tzung-Hai Yen, Jiann-Shing Jeng, Sheng-Feng Sung, Pai-Hao Huang, Jie-Yuan Li, Yu Sun, Cheng-Yu Wei, Li-Ming Lien, I-Ju Tsai, Fung-Chang Sung, Chung Y. Hsu, Taiwan Stroke Registry Investigators Source Type: research

Total cholesterol and stroke mortality in middle-aged and elderly adults: A prospective cohort study
This study aimed to examine the association between total cholesterol (TC) and mortality from total stroke and stroke subtypes.
Source: Atherosclerosis - December 6, 2017 Category: Cardiology Authors: Sang-Wook Yi, Dae-Hee Shin, Hyeyun Kim, Jee-Jeon Yi, Heechol Ohrr Source Type: research

Relationship between thrombus age in aspirated coronary material and mid-term major adverse cardiac and cerebrovascular events in patients with acute myocardial infarction
Recent studies have shown that coronary thrombus histopathology is associated with impaired myocardial reperfusion and poor clinical outcome in patients with acute myocardial infarction (AMI). We sought to investigate the age of thrombi aspirated during percutaneous coronary intervention (PCI) in patients with AMI and evaluate the relationship between histopathologic findings and major adverse cardiac and cerebrovascular events (MACCEs) defined as all-cause death, stroke, or myocardial infarction within 6 months of PCI.
Source: Atherosclerosis - December 2, 2017 Category: Cardiology Authors: Kensaku Nishihira, Yoshisato Shibata, Atsushi Yamashita, Nehiro Kuriyama, Yujiro Asada Source Type: research

Chocolate intake in pre-menopausal women
We have read with great interest the paper “Chocolate consumption and risk of stroke among men and women: A large population-based, prospective cohort study” by Dong and coworkers, published in Atherosclerosis [1], and we have found their conclusion of importance, with a view on clinical prevention.
Source: Atherosclerosis - November 20, 2017 Category: Cardiology Authors: Anna Vittoria Mattioli, Alberto Farinetti Tags: Correspondence Source Type: research

Reply to: “Prognostic value of lipoprotein-associated phospholipase A2 mass for all-cause mortality and vascular events within one year after acute ischemic stroke: Methodological issues”
We are grateful to Ashrafi-Asgarabad et al. for their interest in our article [1]. As we all know, stroke is characterized by high mortality and high recurrence rate, and death is one of the most important outcomes of stroke patients [2]. The aim of our study was to investigate the relationship between Lp-PLA2 mass and poor outcomes, including death and vascular events, after acute ischemic stroke. Using death as our primary outcome was in line with the objective requirements of stroke prognosis studies and consistent with the epidemiological literature [3,4], not just aimed to improve the statistical power.
Source: Atherosclerosis - November 20, 2017 Category: Cardiology Authors: Chongke Zhong, Liyuan Han, Yonghong Zhang Tags: Correspondence Source Type: research

Prognostic value of lipoprotein-associated phospholipase A2 mass for all-cause mortality and vascular events within one year after acute ischemic stroke: Methodological issues
We read with interest the article by Han and colleagues published in Atherosclerosis [1]. The authors purposed to examine the longer-term prognostic value of lipoprotein-associated phospholipase A2 (Lp-PLA2) mass for all-cause mortality and vascular events within one year after acute ischemic stroke. They concluded that elevated Lp-PLA2 mass was independently associated with all cause-death. Certainly, Han et al. have conducted a useful study, but some methodological issues need to be considered.
Source: Atherosclerosis - October 25, 2017 Category: Cardiology Authors: Ahad Ashrafi-Asgarabad, Saeid Safiri Tags: Correspondence Source Type: research

Community-based statins and advanced carotid plaque: Role of CD163 positive macrophages in lipoprotein-associated phospholipase A2 activity in atherosclerotic plaque
Lipoprotein-associated phospholipase A2 (Lp-PLA2), an enzymatic inflammatory biomarker primarily bound to low-density lipoprotein cholesterol, is associated with an approximate twofold increased risk of cardiovascular disease and stroke. Despite indications that circulating Lp-PLA2 is sensitive to statins, it remains largely unknown whether statin usage exerts local effects on Lp-PLA2 expression at the site of atheromatous plaque.
Source: Atherosclerosis - October 13, 2017 Category: Cardiology Authors: Fumiyuki Otsuka, XiaoQing Zhao, Hugh H. Trout, Ye Qiao, Bruce A. Wasserman, Masataka Nakano, Colin H. Macphee, Martin Brandt, Sue Krug-Gourley, Liang Guo, Elena R. Ladich, Qi Cheng, Harry R. Davis, Aloke V. Finn, Renu Virmani, Frank D. Kolodgie Source Type: research

Thoracic extra-coronary calcification for the prediction of stroke: The Multi-Ethnic Study of Atherosclerosis
We examined whether the cumulative burden of thoracic extra-coronary calcification (ECC) improves prediction of stroke, transient ischemic attack (TIA), and stroke mortality beyond traditional risk factors and coronary artery calcium (CAC).
Source: Atherosclerosis - October 7, 2017 Category: Cardiology Authors: Sina Kianoush, Mahmoud Al Rifai, Miguel Cainzos-Achirica, Mouaz H. Al-Mallah, Geoffrey H. Tison, Joseph Yeboah, Michael D. Miedema, Matthew A. Allison, Nathan D. Wong, Andrew P. DeFilippis, William Longstreth, Khurram Nasir, Matthew J. Budoff, Kunihiro Ma Source Type: research

Thoracic extra-coronary calcification for the prediction of stroke: The  Multi-Ethnic Study of Atherosclerosis
We examined whether the cumulative burden of thoracic extra-coronary calcification (ECC) improves prediction of stroke, transient ischemic attack (TIA), and stroke mortality beyond traditional risk factors and coronary artery calcium (CAC).
Source: Atherosclerosis - October 7, 2017 Category: Cardiology Authors: Sina Kianoush, Mahmoud Al Rifai, Miguel Cainzos-Achirica, Mouaz H. Al-Mallah, Geoffrey H. Tison, Joseph Yeboah, Michael D. Miedema, Matthew A. Allison, Nathan D. Wong, Andrew P. DeFilippis, William Longstreth, Khurram Nasir, Matthew J. Budoff, Kunihiro Ma Source Type: research

Dronedarone exerts anticoagulant and antiplatelet effects independently of its antiarrhythmic actions
This study aimed to investigate any direct effect of dronedarone on blood thrombogenicity, independent of its antiarrhythmic effects.
Source: Atherosclerosis - September 28, 2017 Category: Cardiology Authors: M. Urooj Zafar, Carlos G. Santos-Gallego, Donald A. Smith, Jonathan L. Halperin, Juan J. Badimon Source Type: research

Prognostic value of lipoprotein-associated phospholipase A2 mass for all-cause mortality and vascular events within one year after acute ischemic stroke
We performed a prospective investigation of the longer-term prognostic value of lipoprotein-associated phospholipase A2 (Lp-PLA2) mass for all-cause mortality and vascular events within one year after acute ischemic stroke.
Source: Atherosclerosis - September 13, 2017 Category: Cardiology Authors: Liyuan Han, Chongke Zhong, Xiaoqing Bu, Tan Xu, Aili Wang, Yanbo Peng, Tian Xu, Jinchao Wang, Hao Peng, Qunwei Li, Zhong Ju, Deqing Geng, Yonghong Zhang, Jiang He, for the CATIS investigation groups Source Type: research

Cerebral white matter hyperintensity is associated with intracranial atherosclerosis in a healthy population
Cerebral white matter hyperintensity (WMH) is commonly found in ischemic stroke patients, especially when accompanied by intracranial atherosclerosis (ICAS). However, the relationship between WMH and ICAS in a healthy population has not been evaluated.
Source: Atherosclerosis - September 7, 2017 Category: Cardiology Authors: Ki-Woong Nam, Hyung-Min Kwon, Han-Yeong Jeong, Jin-Ho Park, Sang Hyuck Kim, Su-Min Jeong, Tae Gon Yoo, Shinhye Kim Source Type: research

Association of high-density lipoprotein cholesterol concentration with different types of stroke and coronary heart disease: The Japan Public Health Center-based prospective (JPHC) study
Although low high-density lipoprotein (HDL) cholesterol concentration is an established risk factor for coronary heart disease (CHD), information regarding subtypes of stroke is very limited, especially in Asian populations.
Source: Atherosclerosis - September 1, 2017 Category: Cardiology Authors: Isao Saito, Kazumasa Yamagishi, Yoshihiro Kokubo, Hiroshi Yatsuya, Hiroyasu Iso, Norie Sawada, Manami Inoue, Shoichiro Tsugane Source Type: research

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