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Source: Atherosclerosis
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Total 436 results found since Jan 2013.
Correlation of computed tomography with carotid plaque transcriptomes associates calcification with lesion-stabilization
Unstable carotid atherosclerosis causes stroke, but methods to identify patients and lesions at risk are lacking. We recently found enrichment of genes associated with calcification in carotid plaques from asymptomatic patients. Here, we hypothesized that calcification represents a stabilising feature of plaques and investigated how macro-calcification, as estimated by computed tomography (CT), correlates with gene expression profiles in lesions.
Source: Atherosclerosis - May 9, 2019 Category: Cardiology Authors: Eva Karl öf, Till Seime, Nuno Dias, Mariette Lengquist, Anna Witasp, Håkan Almqvist, Malin Kronqvist, Jesper R. Gådin, Jacob Odeberg, Lars Maegdefessel, Peter Stenvinkel, Ljubica Perisic Matic, Ulf Hedin Source Type: research
Correlation of computed tomography with carotid plaque transcriptomes associates calcification to lesion-stabilization
Unstable carotid atherosclerosis causes stroke, but methods to identify patients and lesions at risk are lacking. We recently found enrichment of genes associated with calcification in carotid plaques from asymptomatic patients. Here, we hypothesized that calcification represents a stabilising feature of plaques and investigated how macro-calcification, as estimated by computed tomography (CT), correlates with gene expression profiles in lesions.
Source: Atherosclerosis - May 9, 2019 Category: Cardiology Authors: Eva Karl öf, Till Seime, Nuno Dias, Mariette Lengquist, Anna Witasp, Håkan Almqvist, Malin Kronqvist, Jesper R. Gådin, Jacob Odeberg, Lars Maegdefessel, Peter Stenvinkel, Ljubica Perisic Matic, Ulf Hedin Source Type: research
Progression of brain white matter hyperintensities in asymptomatic patients with carotid atherosclerotic plaques and no indication for revascularization
Brain white matter hyperintensities (WMHs) have been associated with an increased risk of ischemic stroke and considered as markers of brain ischemia. Progression of WMHs in asymptomatic patients with non-hemodynamically significant carotid plaque could represent a putative marker of plaque vulnerability. We prospectively evaluate progression and determinants of WMHs in this population.
Source: Atherosclerosis - May 5, 2019 Category: Cardiology Authors: Enrico Ammirati, Francesco Moroni, Marco Magnoni, Maria A. Rocca, Nicoletta Anzalone, Laura Cacciaguerra, Simona Di Terlizzi, Chiara Villa, Federico Sizzano, Alessio Palini, Isabella Scotti, Francesca Besana, Pietro Spagnolo, Ornella E. Rimoldi, Roberto C Source Type: research
Platelet counts affect the prognostic value of homocysteine in acute ischemic stroke patients
The association between homocysteine and prognosis of ischemic stroke remains controversial, and the role of platelet count on the effects of homocysteine in the prognosis of ischemic stroke is still not elucidated.
Source: Atherosclerosis - April 12, 2019 Category: Cardiology Authors: Xiaowei Zheng, Daoxia Guo, Hao Peng, Chongke Zhong, Xiaoqing Bu, Tan Xu, Zhengbao Zhu, Aili Wang, Jing Chen, Tian Xu, Yanbo Peng, Qunwei Li, Zhong Ju, Deqin Geng, Jiang He, Yonghong Zhang Source Type: research
Large aortic arch plaques correlate with CHADS2 and CHA2DS2-VASc scores in cryptogenic stroke
Current trends have suggested covert atrial fibrillation as a mechanism of cryptogenic stroke. However, etiological heterogeneity regarding the underlying embolic sources remains a critical issue in cryptogenic stroke.
Source: Atherosclerosis - March 18, 2019 Category: Cardiology Authors: Yuji Ueno, Yohei Tateishi, Ryosuke Doijiri, Ayako Kuriki, Takahiro Shimizu, Muneaki Kikuno, Yoshiaki Shimada, Hidehiro Takekawa, Eriko Yamaguchi, Masatoshi Koga, Yuki Kamiya, Masafumi Ihara, Akira Tsujino, Koichi Hirata, Kazunori Toyoda, Yasuhiro Hasegawa Source Type: research
Hearing loss is associated with increased stroke risk in the Dongfeng-Tongji Cohort
The evidence concerning the association between hearing loss and stroke is limited. We aimed to investigate the association of hearing loss with risk of stroke and its subtypes among the middle-aged and older Chinese population.
Source: Atherosclerosis - March 17, 2019 Category: Cardiology Authors: Qin Fang, Xuefeng Lai, Liangle Yang, Zhichao Wang, Yue Zhan, Lue Zhou, Yang Xiao, Hao Wang, Dan Li, Kun Zhang, Tao Zhou, Handong Yang, Huan Guo, Mei-an He, Weijia Kong, Tangchun Wu, Xiaomin Zhang Source Type: research
Post-stroke dementia is associated with increased subsequent all-cause mortality: A population-based cohort study
We aimed to determine whether patients with post-stroke dementia (PSD) have increased mortality risk in Taiwan.
Source: Atherosclerosis - March 12, 2019 Category: Cardiology Authors: Tomor Harnod, Cheng-Li Lin, Chung Y. Hsu, Chia-Hung Kao Source Type: research
Vulnerable plaque and vulnerable blood: Two critical factors for spontaneous atherothrombosis in mouse models
Atherothrombotic events such as myocardial infarction and ischemic stroke are a major cause of morbidity and mortality worldwide. Understanding the molecular and cellular mechanisms of atherosclerotic plaque destabilization or erosion, and developing new therapeutics to prevent acute cardiovascular events are important points for vascular biology research and clinical cardiovascular medicine. However, basic research on plaque destabilization, rupture and erosion is hampered by the lack of appropriate animal models of atherothrombosis.
Source: Atherosclerosis - March 10, 2019 Category: Cardiology Authors: Amber B. Ouweneel, Robin A.F. Verwilligen, Miranda Van Eck Tags: Review article Source Type: research
Associations between statins and coronary artery disease and stroke risks in patients with asthma –chronic obstructive pulmonary disease overlap syndrome: A time-dependent regression study
To determine the effects of statin use on coronary artery disease (CAD) and stroke risks in patients with asthma –chronic obstructive pulmonary disease overlap syndrome (ACOS).
Source: Atherosclerosis - February 11, 2019 Category: Cardiology Authors: Jun-Jun Yeh, Cheng-Li Lin, Chung Y. Hsu, Zonyin Shae, Chia-Hung Kao Source Type: research
The Barcelona-Asymptomatic Intracranial Atherosclerosis study: Subclinical intracranial atherosclerosis as predictor of long-term vascular events
The objective of our study was to determine if subclinical intracranial atherosclerosis is associated with long-term incident vascular events in Caucasians.
Source: Atherosclerosis - January 29, 2019 Category: Cardiology Authors: Anna Planas-Ballv é, Ane Miren Crespo, Lorena MartÃn Aguilar, MarÃa Hernández-Pérez, Tamara Canento, Laura Dorado, MarÃa T. Alzamora, Pere Torán, Guillem Pera, Laura Muñoz-Ortiz, Juan F. Arenillas, MarÃa Castañón, Antoni Dávalos, Mónica Millà Source Type: research
Protective effect of influenza vaccination on outcomes in geriatric stroke patients: A nationwide matched cohort study
The effects of influenza vaccination (IV) on stroke outcomes are unclear. The purpose of this study is to evaluate the outcomes after stroke in elderly individuals who have received an IV.
Source: Atherosclerosis - January 26, 2019 Category: Cardiology Authors: Fai Lam, Ta-Liang Chen, Chun-Chuan Shih, Chao-Shun Lin, Chun-Chieh Yeh, Yuarn-Jang Lee, Chaur-Jong Hu, Hung-Yi Chiou, Chien-Chang Liao Source Type: research
Coronary artery calcium score to guide hypertension therapy!
Hypertension is the most prevalent non-communicable disease, estimated to affect 1.13 billion individuals nowadays. It is the leading preventable cause of mortality worldwide and a major risk factor for coronary artery disease, heart failure, stroke and chronic renal diseases in developed and developing countries.1,2. Worldwide, the aging population, decreased fitness and obesity epidemic have contributed to the increased prevalence of hypertension3. Given that, it poses a significant health and economic challenge to both developed and developing countries.
Source: Atherosclerosis - January 25, 2019 Category: Cardiology Authors: Ahmed Aljizeeri, Ahmed Alsaileek, Mouaz H. Al-Mallah Tags: Editorial Source Type: research
Stroke occurrence while on antiplatelet therapy may predict atrial fibrillation detected after stroke
Stroke occurrence while on antiplatelet therapy, i.e., a breakthrough stroke, is often conveniently attributed to antiplatelet resistance. However, undetected paroxysmal atrial fibrillation (AF) may underlie breakthrough strokes. We hypothesized that a breakthrough stroke may be a clinical marker for patients at risk of having AF detected after stroke (AFDAS).
Source: Atherosclerosis - January 24, 2019 Category: Cardiology Authors: Cheng-Yang Hsieh, Cheng-Han Lee, Sheng-Feng Sung Source Type: research
Association of statin pretreatment with collateral circulation and final infarct volume in acute ischemic stroke patients: A meta-analysis
Statin pretreatment (SP) is associated with improved outcomes in acute ischemic stroke (AIS) patients. Collateral circulation status and final infarct volume (FIV) are independent predictors of functional outcome in AIS.
Source: Atherosclerosis - January 22, 2019 Category: Cardiology Authors: Konark Malhotra, Apostolos Safouris, Nitin Goyal, Adam Arthur, David S. Liebeskind, Aristeidis H. Katsanos, Jo ão Sargento-Freitas, Marc Ribo, Carlos Molina, Jong-Won Chung, Oh Young Bang, Georgios Magoufis, Ahmad Cheema, Steven J. Shook, Ken Uchino, And Source Type: research
TPO-Ab plays a role in arterial remodeling in patients with intracranial stenosis
Intracranial stenosis (ICS), the common cause of ischemic stroke worldwide, is associated with a high risk of recurrent stroke. We aimed to investigate the relationship between arterial remodeling and antithyroid peroxidase-antibody (TPO-Ab) level in ICS and the effect of TPO-Ab level on the migration of vascular smooth muscle cells (VSMCs).
Source: Atherosclerosis - November 27, 2018 Category: Cardiology Authors: Xuting Zhang, Ying Zhou, Wenhong Ding, Ruiting Zhang, Shenqiang Yan, Yujie Deng, Feng Gao, Min Lou Source Type: research
