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Source: Atherosclerosis
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Total 436 results found since Jan 2013.
Statins and the risks of stroke recurrence and death after ischemic stroke: The Fukuoka Stroke Registry
This study aimed to elucidate whether prescribed doses of statins reduce the risks of cerebrovascular events (CVEs: stroke recurrence or transient ischemic attack) and all-cause mortality in a cohort of Japanese patients with first-ever ischemic stroke.Methods: The 2822 eligible patients registered in the Fukuoka Stroke Registry with first-ever acute ischemic stroke from June 2007 to February 2011 were classified into statin users (n = 993) and non-users (n = 1829) at discharge, and followed up until March 2012. We assessed the cumulative risks of CVE and all-cause mortality by the Kaplan–Meier method, and calculated...
Source: Atherosclerosis - November 25, 2013 Category: Cardiology Authors: Noriko Makihara, Masahiro Kamouchi, Jun Hata, Ryu Matsuo, Tetsuro Ago, Junya Kuroda, Takahiro Kuwashiro, Hiroshi Sugimori, Takanari Kitazono, Fukuoka Stroke Registry Investigators Tags: Clinical & Population Research – Intervention Source Type: research
Renal dysfunction increases the risk of recurrent stroke in patients with acute ischemic stroke
This study investigated risks of short-term (1 and 3 months) and long-term (1-year) recurrent stroke associated with glomerular filtration rate (eGFR) in patients with acute ischemic stroke.
Source: Atherosclerosis - July 27, 2018 Category: Cardiology Authors: I-Kuan Wang, Li-Ming Lien, Jiunn-Tay Lee, Chung-Hsiang Liu, Chih-Hung Chen, Ching-Huang Lin, Jiann-Shing Jeng, Chaur-Jong Hu, Tzung-Hai Yen, Sien-Tsong Chen, Hou-Chang Chiu, I-Ju Tsai, Fung-Chang Sung, Chung Y. Hsu, Taiwan Stroke Registry Investigators Source Type: research
Renal function is associated with 1-month and 1-year mortality in patients with ischemic stroke
This study aimed to evaluate the impact of admission estimated glomerular filtration rate (eGFR) levels on short-term (1-month) and long-term (1-year) mortality in patients with acute ischemic stroke.
Source: Atherosclerosis - December 11, 2017 Category: Cardiology Authors: I-Kuan Wang, Chung-Hsiang Liu, Tzung-Hai Yen, Jiann-Shing Jeng, Sheng-Feng Sung, Pai-Hao Huang, Jie-Yuan Li, Yu Sun, Cheng-Yu Wei, Li-Ming Lien, I-Ju Tsai, Fung-Chang Sung, Chung Y. Hsu, Taiwan Stroke Registry Investigators Source Type: research
Effect of intravenous thrombolysis in stroke depends on pattern of intracranial internal carotid artery calcification
The pattern of intracranial internal carotid artery calcification (ICAC) has been identified as an effect modifier of endovascular treatment in patients with acute ischemic stroke, but it is unclear whether it modifies the effect of intravenous thrombolysis. The purpose of this study was to evaluate the association between intravenous thrombolysis and 90-day clinical outcome, follow-up infarct volume, intracranial hemorrhage and recanalization across different patterns of ICAC.
Source: Atherosclerosis - November 22, 2020 Category: Cardiology Authors: Frans Kauw, Pim A. de Jong, Richard A.P. Takx, Hugo W.A.M. de Jong, L. Jaap Kappelle, Birgitta K. Velthuis, Jan W. Dankbaar, Dutch acute stroke study (DUST) investigators Source Type: research
Total and specific fruit and vegetable consumption and risk of stroke: A prospective study
Conclusion: This study shows an inverse association of fruit and vegetable consumption with stroke risk. Particularly consumption of apples and pears and green leafy vegetables was inversely associated with stroke.Highlights: ► Fruit and vegetables is a heterogeneous food group with different content of nutrients. ► It remains unclear which fruit and vegetable subgroups that are most protective against stroke. ► We examined the relation between fruit and vegetable consumption and stroke risk. ► Particularly consumption of apples/pears and green leafy vegetables was inversely associated with stroke.
Source: Atherosclerosis - January 7, 2013 Category: Cardiology Authors: Susanna C. Larsson, Jarmo Virtamo, Alicja Wolk Tags: Epidemiology, Biomarkers, Nutrition Source Type: research
Liver enzymes and stroke risk in middle-aged German adults
Conclusions: Our data provide further evidence for a link between GGT, but not ALT and overall stroke suggesting that these biomarkers are involved in different pathways of disease development. Further studies are needed to clarify the putative relationships between ALT and subtypes of stroke.Highlights:
Source: Atherosclerosis - April 22, 2013 Category: Cardiology Authors: Cornelia Weikert, Dagmar Drogan, Romina di Giuseppe, Andreas Fritsche, Brian Buijsse, Ute Nöthlings, Stefan N. Willich, Klaus Berger, Heiner Boeing Tags: Epidemiology, Biomarkers, Nutrition Source Type: research
Chronic HCV infection is a risk factor of ischemic stroke
Conclusions: HCV infected patients are at higher and earlier risk of stroke. Inflammation is a key mediator. Clinicians in clinical practice and researchers in future trials should take into account these new findings.Highlights:
Source: Atherosclerosis - October 14, 2013 Category: Cardiology Authors: Luigi E. Adinolfi, Luciano Restivo, Barbara Guerrera, Ausilio Sellitto, Antonella Ciervo, Natalina Iuliano, Luca Rinaldi, Aldo Santoro, Giovanni Li Vigni, Aldo Marrone Tags: Clinical & Population Research - Epidemiology, Biomarkers, Nutrition Source Type: research
A functional polymorphism of PON1 interferes with microRNA binding to increase the risk of ischemic stroke and carotid atherosclerosis
Conclusion: Our study is the first to show that the miR-SNP at PON1 could affect genetic expression and is associated with an elevated risk for ischemic stroke and subclinical atherosclerosis.Highlights: ► T allele carriers of PON1 rs3735590 had lower risk of ischemic stroke. ► T allele carriers had thinner intima-media thickness of internal carotid arteries. ► PON1 is a novel direct target gene of miR-616 by 3′UTR reporter assays. ► The binding ability of miR-616 and PON1 gene expression is regulated by SNP rs3735590.
Source: Atherosclerosis - March 15, 2013 Category: Cardiology Authors: Mu-En Liu, Yi-Chu Liao, Ruey-Tay Lin, Yung-Song Wang, Edward Hsi, Hsiu-Fen Lin, Ku-Chung Chen, Suh-Hang H. Juo Tags: Genetics Source Type: research
The relationship between job type and development of cerebral stroke in a large, longitudinal cohort study of workers in a railway company in Japan
Conclusions: Since the present results were adjusted for various behavioral and biological factors, they suggest that train crew work itself is associated with a decreased risk of cerebral stroke. These results suggest that further studies on the effect of driving on health may provide information useful for the future prevention of cerebral stroke.Highlights:
Source: Atherosclerosis - May 3, 2013 Category: Cardiology Authors: Katsuhiro Murata, Kazuhiro Nogawa, Yasushi Suwazono Tags: Epidemiology, Biomarkers, Nutrition Source Type: research
Hyperuricemia and risk of stroke: A systematic review and meta-analysis of prospective studies
Conclusions: Results from this meta-analysis indicate that hyperuricemia may modestly increase the risks of both stroke incidence and mortality. Future studies should explore whether hyperuricemia is a modifiable risk factor for stroke.
Source: Atherosclerosis - January 27, 2014 Category: Cardiology Authors: Min Li, Wenshang Hou, Xiaowei Zhang, Liqin Hu, Zhenyu Tang Tags: Reviews Source Type: research
Dose–response relationship of serum uric acid levels with risk of stroke mortality
Conclusions: Different dose–response relationships of SUA levels with risk of stroke mortality might exist for men and for women. Dose–response relationship of SUA levels with risk of stroke incidence needs to be explored.
Source: Atherosclerosis - April 10, 2014 Category: Cardiology Authors: Junqian Huang, Dan Hu, Yuchun Wang, Dongfeng Zhang, Yan Qu Tags: Letters to the Editor Source Type: research
Stroke in sickle cell anemia patients: A need for multidisciplinary approaches
Abstract: Sickle cell anemia (SCA) is an autosomal recessive disorder, with Mendelian inheritance pattern, caused by a missense mutation in the β-polypeptide chain of the hemoglobin B. SCA preferentially affects populations in countries where malaria was/is present (e.g. Africa, USA, Brazil). Thereby, in USA, the incidence of SCA is relatively high, around 1/500, and the prevalence is about 1/1000. In Brazil, SCA represents a major public health problem with an incidence ranging from 1/2000 to 1/600 depending on the regions. Homozygotic patients present more severe medical conditions and reduced life expectancy than heter...
Source: Atherosclerosis - June 10, 2013 Category: Cardiology Authors: Farid Menaa Tags: Reviews Source Type: research
Ankle–brachial index predicts stroke in the general population in addition to classical risk factors
Abstract: Background: Predictors of future stroke events gain importance in vascular medicine. Herein, we investigated the value of the ankle-brachial index (ABI), a simple non-invasive marker of atherosclerosis, as stroke predictor in addition to established risk factors that are part of the Framingham risk score (FRS).Methods: 4299 subjects from the population-based Heinz Nixdorf Recall study (45–75 years; 47.3% men) without previous stroke, coronary heart disease or myocardial infarcts were followed up for ischemic and hemorrhagic stroke events over 109.0 ± 23.3 months. Cox proportional hazard regressions were used...
Source: Atherosclerosis - March 20, 2014 Category: Cardiology Authors: Janine Gronewold, Dirk M. Hermann, Nils Lehmann, Knut Kröger, Karl Lauterbach, Klaus Berger, Christian Weimar, Hagen I.M. Kälsch, Susanne Moebus, Karl-Heinz Jöckel, Marcus Bauer, Raimund Erbel, Heinz Nixdorf Recall Study Investigative Group Tags: Clinical & Population Research - Epidemiology, Biomarkers, Nutrition Source Type: research
Low levels of high-density lipoprotein cholesterol in patients with atherosclerotic stroke: A prospective cohort study
Abstract: Objective: The purpose of this study was to evaluate the influence of baseline high-density lipoprotein cholesterol (HDL-C) on initial stroke severity and clinical outcomes in acute ischemic stroke.Methods: From August 2006 through December 2011, patients with acute atherosclerotic ischemic stroke were included. Total cholesterol, triglycerides, low-density lipoprotein cholesterol (LDL-C) and HDL-C were checked and National Institutes of Health Stroke Scale (NIHSS) scores were obtained at admission. The primary outcomes were a composite end point of all-cause mortality, recurrent stroke, or occurrence of ischemic...
Source: Atherosclerosis - April 25, 2013 Category: Cardiology Authors: Poh-Shiow Yeh, Chun-Ming Yang, Sheng-Hsiang Lin, Wei-Ming Wang, Po-Sheng Chen, Ting-Hsing Chao, Huey-Juan Lin, Kao-Chang Lin, Chia-Yu Chang, Tain-Junn Cheng, Yi-Heng Li Tags: Epidemiology, Biomarkers, Nutrition Source Type: research
Overall diet quality and risk of stroke: A prospective cohort study in women
In conclusion, these findings suggest that a diet including a variety of healthy foods and few less healthy foods may reduce stroke risk.Highlights:
Source: Atherosclerosis - February 18, 2014 Category: Cardiology Authors: Susanna C. Larsson, Agneta Åkesson, Alicja Wolk Tags: Clinical & Population Research - Epidemiology, Biomarkers, Nutrition Source Type: research
