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Source: Atherosclerosis
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Total 436 results found since Jan 2013.
Imaging the aortic arch to improve diagnostic and prognostic accuracy in transient ischemic attack patients
This study raises a final relevant question: since the prognosis of TIA patients worsens in proportion to the severity of AAA, what therapeutic options are available for these patients? The clinical guidelines recommend risk factor modification and therapy with statins (Class IIa, level of evidence C), an approach consistent with treatment of any patient affected by atherosclerosis. Treatment with coumadin or anti-platelet agents can be considered in patients with AAA >4 mm, i.e. severe AAA, but it remains very controversial because of a potential risk of thrombo-embolism (Class IIb, level of evidence C) . Finally, surgi...
Source: Atherosclerosis - November 25, 2013 Category: Cardiology Authors: Paolo Raggi Tags: Invited Commentaries Source Type: research
Serum calcium and phosphate concentrations and intracranial atherosclerosis
Conclusion: Corrected serum calcium concentrations are positively associated with the presence of intracranial atherosclerosis.Highlights:
Source: Atherosclerosis - January 1, 2014 Category: Cardiology Authors: K. Kang Tags: Clinical & Population Research - Epidemiology, Biomarkers, Nutrition Source Type: research
Rosuvastatin may stabilize atherosclerotic aortic plaque: Transesophageal echocardiographic study in the EPISTEME trial
This study sought to analyze the temporal profile of AAPs after rosuvastatin therapy in Japanese patients with acute ischemic stroke.
Source: Atherosclerosis - February 16, 2015 Category: Cardiology Authors: Yuji Ueno, Kazuo Yamashiro, Yasutaka Tanaka, Masao Watanabe, Nobukazu Miyamoto, Yoshiaki Shimada, Takuma Kuroki, Ryota Tanaka, Katsumi Miyauchi, Hiroyuki Daida, Nobutaka Hattori, Takao Urabe Source Type: research
Strokes, cholesterol and statins: When mortality is an endpoint
The Yi et al. stroke mortality study, with 5.2 million person-years of observation in a representative Korean population cohort with a single baseline total cholesterol (TC) measurement, highlights several important issues [1]. First, the authors note the fact that cholesterol lowering “particularly by statins” does not lower stroke mortality in randomized trials. Second, the fact that 53% of stroke deaths were from hemorrhagic strokes, far surpassing its incidence of about 10–20% in all strokes in many countries [1], and that are mainly nonfatal ischemic strokes.
Source: Atherosclerosis - May 2, 2018 Category: Cardiology Authors: Eddie Vos, Pierre Biron Tags: Correspondence Source Type: research
Effect of initiating statin therapy on long-term outcomes of patients with dyslipidemia after intracerebral hemorrhage
Intracerebral hemorrhage (ICH) has a higher mortality than ischemic stroke. Statin is beneficial for stroke, but high potency statin treatment has been associated with the risk of hemorrhagic stroke. The aim of this study was to assess the impact of initiating statin therapy after ICH on cardiovascular outcomes.
Source: Atherosclerosis - July 10, 2019 Category: Cardiology Authors: Ming-Shyan Lin, Yu-Sheng Lin, Shih-Tai Chang, Po-Chang Wang, Victor Chien-Chia Wu, Wey-Yil Lin, Chang-Min Chung Source Type: research
Leukocytes, platelets and cardiovascular diseases
We read with great interest the recent article in Atherosclerosis by Xu et al. [1]. In a large prospective study comprising 13,929 middle age and elderly individuals of Chinese descent, they showed that the systemic immune-inflammation index (SII), the product of the neutrophil count x platelet count x lymphocyte count, predicted total stroke, ischemic stroke and hemorrhagic stroke over a median follow-up of 8.3 years using multivariate Cox regression analyses [1]. Although there was a threefold increase in coronary heart disease (CAD), SII did not predict CAD or acute coronary syndromes (ACS).
Source: Atherosclerosis - May 7, 2021 Category: Cardiology Authors: Ishwarlal Jialal, Beverley Adams-Huet Tags: Correspondence Source Type: research
Carotid intima-media thickness for cardiovascular risk assessment: Systematic review and meta-analysis
Conclusions: CIMT as measured by B-mode ultrasound is associated with future cardiovascular events. However, the addition of CIMT to traditional cardiovascular risk prediction models does not lead to a statistical significantly increase in performance of those models.
Source: Atherosclerosis - February 11, 2013 Category: Cardiology Authors: Stijn C.H. van den Oord, Eric J.G. Sijbrands, Gerrit L. ten Kate, David van Klaveren, Ron T. van Domburg, Antonius F.W. van der Steen, Arend F.L. Schinkel Tags: Reviews Source Type: research
Serum total adiponectin level and the risk of cardiovascular disease in general population: A meta-analysis of 17 prospective studies
Conclusions: Increased serum adiponectin was related to an elevated risk of ischemic stroke, but there was no clear evidence indicating a positive relationship between adiponectin and the risk of CHD or CVD.
Source: Atherosclerosis - March 14, 2013 Category: Cardiology Authors: Guang Hao, Wei Li, Rui Guo, Jin-Gang Yang, Yang Wang, Yu Tian, Man-Yun Liu, Ya-Guang Peng, Zeng-Wu Wang Tags: Reviews Source Type: research
Renal function and short-term outcome in stable outpatients with coronary, cerebrovascular or peripheral artery disease
Abstract: Background: The influence of renal function on outcome in stable outpatients with atherosclerotic disease has not been thoroughly studied.Methods: We used the FRENA Registry data to compare the incidence of subsequent ischemic events (myocardial infarction [MI], ischemic stroke or limb amputation) in patients with coronary (CAD), cerebrovascular (CVD) or peripheral artery disease (PAD), according to their estimated glomerular filtration rate (eGFR) at baseline.Results: As of April 2012, 3860 patients were recruited in FRENA: 1439 with CAD, 1118 with CVD and 1303 with PAD. Over a mean follow-up of 14±12 months, 9...
Source: Atherosclerosis - May 28, 2013 Category: Cardiology Authors: Davide Bernaudo, Ramón Coll, Juan F. Sánchez Muñoz-Torrero, María Teresa Pascual, Ana María García-Díaz, Lorenzo Ramón Álvarez, Manuel Monreal, the FRENA Investigators Tags: Epidemiology, Biomarkers, Nutrition Source Type: research
Haptoglobin 2 allele associates with unstable carotid plaque and major cardiovascular events
Conclusion: Common haptoglobin variants modulate the inflammatory response to IPH and associate with the risk of unstable carotid stenosis and major ischemic cardiovascular events.Highlights:
Source: Atherosclerosis - September 26, 2013 Category: Cardiology Authors: Petra Ijäs, Jani Saksi, Lauri Soinne, Jarno Tuimala, Matti Jauhiainen, Antti Jula, Mika Kähönen, Y. Antero Kesäniemi, Petri T. Kovanen, Markku Kaste, Perttu J. Lindsberg Tags: Clinical & Population Research - Genetics Source Type: research
Long-chain n-3 polyunsaturated fatty acids intake and cardiovascular disease mortality risk in Japanese: A 24-year follow-up of NIPPON DATA80
Conclusion: LCn3FA intake was inversely and independently associated the long-term risk of total CVD mortality in a representative sample of Japanese with high LCn3FA intake.Highlights:
Source: Atherosclerosis - January 27, 2014 Category: Cardiology Authors: Naoko Miyagawa, Katsuyuki Miura, Nagako Okuda, Takashi Kadowaki, Naoyuki Takashima, Shin-ya Nagasawa, Yasuyuki Nakamura, Yasuhiro Matsumura, Atsushi Hozawa, Akira Fujiyoshi, Takashi Hisamatsu, Katsushi Yoshita, Akira Sekikawa, Takayoshi Ohkubo, Robert D. Tags: Clinical & Population Research - Epidemiology, Biomarkers, Nutrition Source Type: research
Association of the novel single-nucleotide polymorphism which increases oxidized low-density lipoprotein levels with cerebrovascular disease events
Conclusions: The oxLDL levels increasing variant rs676210 associates with CVD events in patients undergoing coronary angiography.
Source: Atherosclerosis - April 10, 2014 Category: Cardiology Authors: Kari-Matti Mäkelä, Matthew Traylor, Niku Oksala, Marcus E. Kleber, Ilkka Seppälä, Leo-Pekka Lyytikäinen, Jussi A. Hernesniemi, Mika Kähönen, Steve Bevan, Peter M. Rothwell, Cathie Sudlow, Martin Dichgans, Graciela Delgado, Tanja B. Grammer, Hubert Tags: Clinical & Population Research - Genetics Source Type: research
Parental history and the risk of subsequent vascular events in patients with clinically manifest vascular disease: The effects of sex of the parent and vascular disease location
Conclusions: A positive parental history of cardiovascular disease without information about vascular disease location and sex does not increase the risk of recurrent vascular events in patients with symptomatic vascular disease. Vascular patients with a father with PAD have an increased risk of subsequent peripheral artery disease compared with vascular patients without such a family history.Highlights:
Source: Atherosclerosis - April 10, 2014 Category: Cardiology Authors: Maaike Weijmans, Yolanda van der Graaf, Gert Jan de Borst, Hendrik M. Nathoe, Ale Algra, Frank L.J. Visseren, the SMART study group Tags: Clinical & Population Research - Epidemiology, Biomarkers, Nutrition Source Type: research
The association Baseline NIH Stroke Scale Score with ABO blood-Subtypes in young patients With Acute Ischemic Stroke
Source: Atherosclerosis - July 10, 2014 Category: Cardiology Authors: Ning Yang, Bin Zhang, Longchang Xie, Jianrui Yin, Yihua He, Xinguang Yang, Cong Gao Source Type: research
Elevated fasting glucose as a potential predictor for asymptomatic cerebral artery stenosis: A cross-sectional study in Chinese adults
Cerebral artery stenosis is known as an important cause of stroke, and elevated fasting glucose level is also considered as a risk factor for stroke. Our aim was to exam whether elevated fasting glucose is associated with cerebral artery stenosis, especially asymptomatic cerebral artery stenosis.
Source: Atherosclerosis - October 23, 2014 Category: Cardiology Authors: Jing Wang, Jianwei Wu, Shufeng Zhang, Liqun Zhang, Chunxue Wang, Xiang Gao, Yong Zhou, Anxin Wang, Shouling Wu, Xingquan Zhao Source Type: research
