Strokes, cholesterol and statins: When mortality is an endpoint

The Yi et al. stroke mortality study, with 5.2 million person-years of observation in a representative Korean population cohort with a single baseline total cholesterol (TC) measurement, highlights several important issues [1]. First, the authors note the fact that cholesterol lowering “particularly by statins” does not lower stroke mortality in randomized trials. Second, the fact that 53% of stroke deaths were from hemorrhagic strokes, far surpassing its incidence of about 10–20% in all strokes in many countries [1], and that are mainly nonfatal ischemic strokes.

Source: Atherosclerosis - May 2, 2018 Category: Cardiology Authors: Eddie Vos, Pierre Biron Tags: Correspondence Source Type: research