Filtered By:
Source: Atherosclerosis
This page shows you your search results in order of date. This is page number 14.
Order by Relevance | Date
Total 436 results found since Jan 2013.
Macrophage expression of interleukin-37 attenuates atherosclerosis
This study was undertaken to elucidate the role of macrophage-expressed IL-37 in reducing the production and effects of pro-inflammatory cytokines, preventing foam cell formation, and reducing the development of atherosclerosis.
Source: Atherosclerosis - August 1, 2018 Category: Cardiology Authors: W. Boisvert, S. McCurdy, Y. Baumer Tags: Immune Regulation in Atherosclerosis Source Type: research
Elevated LDL cholesterol from birth is associated with different risk of various types of atherosclerotic disease
Aim: Objective It is generally accepted that LDL cholesterol play a more important role for the development of coronary heart disease than for ischemic stroke. The aim of this study was to explore the role of LDL cholesterol in different types of atherosclerotic disease. We used subjects with a pathogenic familial hypercholesterolemia (FH) mutation as a model to explore the isolated role of elevated LDL cholesterol.
Source: Atherosclerosis - August 1, 2018 Category: Cardiology Authors: L.J. Mundal, J. Igland, K.B. Holven, M.P. Bogsrud, T.P. Leren, K. Retterstol Tags: Clinical Aspects of Lipids, Genetics, and Interventions II Source Type: research
Renal dysfunction increases the risk of recurrent stroke in patients with acute ischemic stroke
This study investigated risks of short-term (1 and 3 months) and long-term (1-year) recurrent stroke associated with glomerular filtration rate (eGFR) in patients with acute ischemic stroke.
Source: Atherosclerosis - July 27, 2018 Category: Cardiology Authors: I-Kuan Wang, Li-Ming Lien, Jiunn-Tay Lee, Chung-Hsiang Liu, Chih-Hung Chen, Ching-Huang Lin, Jiann-Shing Jeng, Chaur-Jong Hu, Tzung-Hai Yen, Sien-Tsong Chen, Hou-Chang Chiu, I-Ju Tsai, Fung-Chang Sung, Chung Y. Hsu, Taiwan Stroke Registry Investigators Source Type: research
Prognostic value of pulse pressure after an acute coronary syndrome
Pulse pressure (PP) is a surrogate of aortic stiffness (AS) easily obtainable. The link between AS and cardio-vascular disease is documented, however, data regarding acute coronary syndrome (ACS) patients are scarce and contradictory. We aimed to assess the prognostic value of PP measured at admission, with regard to major adverse outcomes (all-cause mortality, recurrence of MI, and stroke), during the first year following an acute coronary syndrome (ACS).
Source: Atherosclerosis - July 15, 2018 Category: Cardiology Authors: Brahim Harbaoui, David Nanchen, Pierre Lantelme, Baris Gencer, Dick Heg, Roland Klingenberg, Lorenz R äber, David Carballo, Christian M. Matter, Stephan Windecker, François Mach, Nicolas Rodondi, Eric Eeckhout, Pierre Monney, Panagiotis Antiochos, Juerg Source Type: research
Risk factors for atherosclerotic and medial arterial calcification of the intracranial internal carotid artery
Calcifications of the intracranial internal carotid artery (iICA) are an important risk factor for stroke. The calcifications can occur both in the intimal and medial layer of the vascular wall. The aim of this study is to assess whether medial calcification in the iICA is differently related to risk factors for cardiovascular disease, compared to intimal calcification.
Source: Atherosclerosis - July 7, 2018 Category: Cardiology Authors: Annelotte Vos, Remko Kockelkoren, Jill B. de Vis, Yvonne T. van der Schouw, Irene C. van der Schaaf, Birgitta K. Velthuis, Willem P.T.M. Mali, Pim A. de Jong, the DUST study group Source Type: research
Cirrhosis and risk of stroke: A systematic review and meta-analysis
Several studies have reported that cirrhosis may increase the risk of stroke. However, its association is controversial. We conducted a systematic review and meta-analysis to investigate the relationship between cirrhosis and the risk of stroke.
Source: Atherosclerosis - June 21, 2018 Category: Cardiology Authors: Jianping Xiong, Weiyu Xu, Hanchun Huang, Jin Bian, Anqiang Wang, Yi Bai, Jianzhen Lin, Yiyao Xu, Xin Lu, Haitao Zhao Source Type: research
Risk factors of pure leukoaraiosis and the association with preclinical carotid atherosclerosis
In this study, we investigated the risk factors of pure leukoaraiosis (without stroke), and the association with preclinical carotid atherosclerosis.
Source: Atherosclerosis - June 20, 2018 Category: Cardiology Authors: Xueying Yu, Guihong Wang, Jiong Zhan, Zaiqiang Zhang, Tao Feng, Jun Xu Source Type: research
Loss of CLOCK under high glucose upregulates ROCK1-mediated endothelial to mesenchymal transition and aggravates plaque vulnerability
Carotid atherosclerotic plaque is one of the main sources of ischemic stroke, and endothelial-to-mesenchymal transition (EndMT) is a major feature of atherosclerosis. Rho-associated coiled-coil-containing protein kinase 1 (ROCK1) activation, stimulated by high glucose, plays an important role in EndMT, and circadian locomotor output cycles protein kaput (Clock) deficiency leads to hyperglycemia and enhanced atherosclerosis in Clock Δ19/Δ19 apolipoprotein E (ApoE)−/− mice. These findings point to a mechanism whereby CLOCK exerts a protective effect against EndMT and atherosclerotic plaque accumulation.
Source: Atherosclerosis - May 24, 2018 Category: Cardiology Authors: Hanfei Tang, Mengjiao Zhu, Gefei Zhao, Weiguo Fu, Zhenyu Shi, Yong Ding, Xiao Tang, Daqiao Guo Source Type: research
Escaping the atherogenic trap: Preventing LDL fusion and binding in the intima
Low-density lipoprotein (LDL) cholesterol plasma concentrations have served as the target of clinical treatment of atherosclerosis-related diseases since the development of simvastatin three decades ago. Targeting endogenous cholesterol synthesis by the inhibition of β-hydroxy-β-methylglutaryl co-enzyme A (HMG-CoA) reductase, statins have since become a mainstay in the lowering of plasma cholesterol and LDL levels and the improvement of cardiovascular outcomes such as myocardial infarction and stroke.
Source: Atherosclerosis - May 18, 2018 Category: Cardiology Authors: Martin Houde, Miranda Van Eck Tags: Editorial Source Type: research
Left ventricular hypertrophy assessed by electrocardiogram is associated with more severe stroke and with higher in-hospital mortality in patients with acute ischemic stroke
Left ventricular hypertrophy (LVH), assessed by electrocardiogram (ECG), is associated with increased risk for stroke. However, few studies that evaluated whether ECG-detected LVH predicts ischemic stroke severity and outcome. We aimed to evaluate these associations.
Source: Atherosclerosis - May 17, 2018 Category: Cardiology Authors: Konstantinos Tziomalos, Areti Sofogianni, Stella-Maria Angelopoulou, Konstantinos Christou, Stavroula Kostaki, Marianthi Papagianni, Sarantis Satsoglou, Marianna Spanou, Christos Savopoulos, Apostolos I. Hatzitolios Source Type: research
Ischemic stroke/transient ischemic attack events and carotid artery disease in the absence of or with minimal coronary artery calcification: Results from the Multi-Ethnic Study of Atherosclerosis
The association between minimally elevated coronary artery calcification (CAC) and cerebrovascular disease is not well known. We assessed whether individuals with minimal CAC (Agatston scores of 1 –10) have higher ischemic stroke or transient ischemic attack (TIA) frequencies compared with those with no CAC. We also investigated the relative prevalence of carotid atherosclerosis in these two groups.
Source: Atherosclerosis - May 17, 2018 Category: Cardiology Authors: Kazuhiro Osawa, Rine Nakanishi, Robyn L. McClelland, Joseph F. Polak, Warrick Bishop, Ralph L. Sacco, Indre Ceponiene, Negin Nezarat, Sina Rahmani, Hong Qi, Mitsuru Kanisawa, Matthew J. Budoff Source Type: research
Prognostic significance of serum cystatin C in acute ischemic stroke patients according to lipid component levels
Serum cystatin C (CysC) is associated with the risk of ischemic stroke and may predict cardiovascular events and death after ischemic stroke onset. However, the association between serum CysC and functional outcome in ischemic stroke patients remains unclear, and whether lipid component level influences the relationship between them has not been studied.
Source: Atherosclerosis - May 11, 2018 Category: Cardiology Authors: Zhengbao Zhu, Chongke Zhong, Tian Xu, Aili Wang, Yanbo Peng, Tan Xu, Hao Peng, Chung-Shiuan Chen, Jinchao Wang, Qunwei Li, Deqin Geng, Yingxian Sun, Yongqiu Li, Yonghong Zhang, Jiang He Source Type: research
Strokes, cholesterol and statins: When mortality is an endpoint
The Yi et al. stroke mortality study, with 5.2 million person-years of observation in a representative Korean population cohort with a single baseline total cholesterol (TC) measurement, highlights several important issues [1]. First, the authors note the fact that cholesterol lowering “particularly by statins” does not lower stroke mortality in randomized trials. Second, the fact that 53% of stroke deaths were from hemorrhagic strokes, far surpassing its incidence of about 10–20% in all strokes in many countries [1], and that are mainly nonfatal ischemic strokes.
Source: Atherosclerosis - May 2, 2018 Category: Cardiology Authors: Eddie Vos, Pierre Biron Tags: Correspondence Source Type: research
Hepatocyte growth factor is associated with progression of atherosclerosis: The Multi-Ethnic Study of Atherosclerosis (MESA)
Hepatocyte growth factor (HGF) has previously been associated with risk of stroke, coronary heart disease, and atherosclerosis. We hypothesized that higher circulating HGF is associated with greater progression of measures of atherosclerosis: coronary artery calcium (CAC) and carotid plaque.
Source: Atherosclerosis - March 26, 2018 Category: Cardiology Authors: Elizabeth J. Bell, Paul A. Decke, Michael Y. Tsa, James S. Panko, Naomi Q. Hanso, Christina L. Wasse, Nicholas B. Larso, Kevin P. Cohoo, Matthew J. Budof, Joseph F. Pola, James H. Stei, Suzette J. Bielinsk Source Type: research
