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Source: Atherosclerosis
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Total 436 results found since Jan 2013.
Serum content of saturated fatty acids and the prevalence of atrial fibrillation - A norwegian cross-sectional study
Aim: Atrial fibrillation [AF] is a common cardiac arrhythmia with serious clinical consequences including a 5-fold higher risk of ischemic stroke. Serum content of saturated fatty acids (SFA) consisting of palmitic (C16:0) and stearic (C18:0) acid may be associated with the prevalence of AF.
Source: Atherosclerosis - August 1, 2018 Category: Cardiology Authors: P. Dinesen, S. Tveit, A. Kalstad, P. Myhre, K. Laake, S. Solheim, H. Arnesen, E.B. Schmidt, S. Lundbye-Christensen, I. Seljeflot Source Type: research
Photomechanical effect of Q-switched ND:YAG laser enhance thrombolysis using of PLGA- based encapsulated tissue plasminogen activator (TPA) nanoparticles
Aim: Thrombus formation on a disrupted atherosclerotic plaque is a key event that leads to atherothrombosis. Atherothrombosis mediated acute clinical events such as myocardial infarction and stroke. The purpose of this study is to prepare encapsulated tissue plasminogen activator (tPA) and evaluate its effectiveness on thrombolysis using laser therapy in the rabbit model of atherothrombotic.
Source: Atherosclerosis - August 1, 2018 Category: Cardiology Authors: H. Mehrad, J. Mahmoudi, A. Keshavarz, A. Rahimkhani Source Type: research
Glucagon-like peptide 1 receptor agonists and protection against stroke: a systematic review and meta-analysis
Aim: Glucagon-like peptide 1 receptor (GLP-1R) agonists, a novel class of antidiabetic agents, have been reported to exert neuroprotective effects in experimental stroke models, especially if treatment starts before stroke. We aimed to assess available data regarding the risk of stroke in diabetic individuals treated with GLP-1R agonists.
Source: Atherosclerosis - August 1, 2018 Category: Cardiology Authors: H. Milionis, F. Barkas, M. Elisaf Tags: Diabetes and Vascular Risk Source Type: research
Gut microbiota-dependent TMAO, aortic atherosclerosis and risk of cardiovascular events in patients with stroke
Aim: In experimental studies gut microbiota-dependent metabolites, in particular trimethylamine N-oxide (TMAO), have recently been reported to promote atherosclerosis. Here, we examined for the first time the relation of TMAO with the severity of aortic atherosclerosis and the risk of incident cardiovascular events (CVE) in patients with recent first-ever ischemic stroke.
Source: Atherosclerosis - August 1, 2018 Category: Cardiology Authors: A. Haghikia, X.S. Li, T. Liman, C. Widera, K. Sonnenschein, A. Haghikia, K. Weissenborn, J. Bauersachs, U. Bavendiek, S.L. Hazen, M. Endres, U. Landmesser Source Type: research
Gene polymorphisms of MMPS-7, -9, -13 and -14 are predictors of aggravation in coronary artery disease?
Aim: Atherosclerotic plaque rupture is the primary cause for myocardial infarction and stroke. Matrix metalloproteinases (MMPs) play an important role in inflammation and extracellular matrix degradation leading to plaque rupture.
Source: Atherosclerosis - August 1, 2018 Category: Cardiology Authors: A. Ben Braiek, B. Baudin, C. Delomenie, F. Dumont, H. Chahed, H. Gamra, F. Maatouk Source Type: research
The role of HbA1c on mortality in patients with medical history of ischemic stroke and paroxysmal atrial fibrillation (pAfib)
Aim: The correlation of HbA1c level with mortality in patients with ischemic stroke and pAfib.
Source: Atherosclerosis - August 1, 2018 Category: Cardiology Authors: K. Kanellopoulou, I.L. Matsoukis, T. Athanasopoulou, A. Ganotopoulou, N. Zimpounoumi, C. Triantafillopoulou, D. Klonos, L. Skorda, A. Sianni Source Type: research
Macrophage-based models for diagnostics and therapy development
Aim: Immunopathology plays important roles in the development of different life-threatening diseases, such as atherosclerosis and its consequences (acute myocardial infarction and stroke), cancer, chronic inflammatory diseases. Effective modulation of the immune system may significantly increase the efficacy of prevention and therapy efforts. We have developed a test system designed for complex analysis of human monocyte-derived macrophage activity in individuals to diagnose immunopathology and monitor treatment efficacy.
Source: Atherosclerosis - August 1, 2018 Category: Cardiology Authors: A. Melnichenko, T. Kirichenko, M. Stepanova, A. Orekhov Source Type: research
Study of associations of polymorphic variants of lipid and carbohydrate metabolism genes, vascular inflammation and neurotransmitter systems with the development of the first ischemic stroke
Aim: Goal. To study the relationship between polymorphic variants of the following genes: APOE, MTHFR, IL8, IL6, TNF-a, VEGFA, ADIPOQ, ADIROR, APOB, APOA-V, APOC-IV, LPL, LP (a), BDNF, GRM1, GRM3 and development the first ischemic stroke .
Source: Atherosclerosis - August 1, 2018 Category: Cardiology Authors: V. Shishkova, A. Remennik, V. Valyaeva, T. Adasheva Source Type: research
Association between serum uric acid and atherosclerotic carotid disease in patients with acute ischemic stroke
Aim: The role of serum uric acid (SUA )in ischemic stroke is controversial. We aim to investigate the association of SUA levels with carotid disease in patients with atherosclerotic ischemic stroke.
Source: Atherosclerosis - August 1, 2018 Category: Cardiology Authors: J.C. Ar évalo-Lorido, J. Carretero-Gómez, N.R. Robles Source Type: research
Characteristics and ten-year prognosis of patients treated with aspirin prior to a first-ever acute ischemic stroke. Data from the ‘Athens stroke outcome project’
Aim: To assess the clinical characteristics and the ten-year prognosis of patients treated with aspirin prior to a first-ever acute ischemic non-cardioembolic stroke (AINCS).
Source: Atherosclerosis - August 1, 2018 Category: Cardiology Authors: H. Milionis, F. Barkas, G. Ntaios, E. Koromboki, V. Papavasileiou, K. Vemmos Source Type: research
Antibodies against HDL components improve the diagnostic accuracy between ischemic stroke or coronary artery disease and healthy controls when added to traditional cardiovascular risk factors
This study aims to investigate whether these antibodies had additional value to traditional CV risk factors for the diagnosis of IS and CAD.
Source: Atherosclerosis - August 1, 2018 Category: Cardiology Authors: J. Batuca, M. Amaral, C. Favas, G. Justino, A. Papoila, P. Ames, J. Delgado Alves Source Type: research
Distribution of lipoprotein (a) in a population with cardiovascular events or dyslipidaemia
Aim: High level of lipoprotein(a) has been demonstrated to be an independent cardiovascular risk factor. However epidemiological data about Lp(a) levels in different patient cohorts are scarce. We aim to describe values of Lp(a) in a population of northern Spain with high cardiovascular risk (stroke or acute myocardial infarction) or dyslipidaemia.
Source: Atherosclerosis - August 1, 2018 Category: Cardiology Authors: A.R. Guerra Ruiz, B.A. Lavin Gomez, E.J. Palacio Portilla, Y. Jimenez Lopez, J.L. Hernandez Hernandez, C. Garc ía Ibarbia, N. Royuela Martinez, M.T. Garcia Unzueta, J.A. Vazquez de Prada Source Type: research
High lipoprotein(A) level is a predictor of severe carotid atherosclerosis and ischemic stroke
The objective of the study was to evaluate an association of Lp(a) level with severe carotid atherosclerosis and non-fatal ischemic stroke.
Source: Atherosclerosis - August 1, 2018 Category: Cardiology Authors: N. Tmoyan, M. Ezhov, O. Afanasieva, M. Afanasieva, T. Balakhonova, S. Pokrovsky Tags: 2.3 Lipoproteins: Lp (a) Source Type: research
Obesity is an independent risk factor for pneumonia in patients admitted with acute ischemic stroke
Aim: Patients admitted with acute ischemic stroke have increased risk for pneumonia. However, apart from the association between stroke severity and the incidence of pneumonia, there are limited data regarding the risk factors for developing pneumonia in this population. We aimed to identify these risk factors.
Source: Atherosclerosis - August 1, 2018 Category: Cardiology Authors: M. Papagianni, K. Tziomalos, S. Kostaki, S. Angelopoulou, K. Christou, A. Sofogianni, S. Alkagiet, G. Chatzopoulos, C. Savopoulos, A. Hatzitolios Tags: Obesity Source Type: research
TREM2 deficiency increases plasma cholesterol and triglyceride levels without influencing lesion formation in LDLR-deficient mice
Aim: Triggering receptor expressed on myeloid cells 2 (Trem2) is a modulatory receptor on the surface of macrophages and immature dendritic cells with yet unknown ligands. Functionally, Trem2 has been suggested to both promote phagocytosis and suppress the secretion of TLR-induced inflammatory cytokines. However, recent studies demonstrated an attenuated inflammatory reaction following stroke in Trem2-deficient mice. Here, we sought to evaluate the effect of Trem2 deficiency on atherosclerotic lesion formation.
Source: Atherosclerosis - August 1, 2018 Category: Cardiology Authors: M. Kiss, F.S. Porsch, A. Hladik, L. G öderle, O. Sharif, S. Knapp, C.J. Binder Source Type: research
