Photomechanical effect of Q-switched ND:YAG laser enhance thrombolysis using of PLGA- based encapsulated tissue plasminogen activator (TPA) nanoparticles

Aim: Thrombus formation on a disrupted atherosclerotic plaque is a key event that leads to atherothrombosis. Atherothrombosis mediated acute clinical events such as myocardial infarction and stroke. The purpose of this study is to prepare encapsulated tissue plasminogen activator (tPA) and evaluate its effectiveness on thrombolysis using laser therapy in the rabbit model of atherothrombotic.
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research