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Condition: Patent Foramen Ovale

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Total 1415 results found since Jan 2013.

Cardiac and Echocardiographic Markers in Cryptogenic Stroke with Incidental Patent Foramen Ovale
Some cardiac abnormalities could be a substrate for potential embolic source in cryptogenic stroke (CS). We evaluated whether cardiac and echocardiographic markers were associated with CS in patients with incidental patent foramen ovale (PFO) as defined using the Risk of Paradoxical Embolism (RoPE) score.
Source: Journal of Stroke and Cerebrovascular Diseases - June 6, 2021 Category: Neurology Authors: Yohei Tateishi, Yuji Ueno, Akira Tsujino, Ayako Kuriki, Yuki Kamiya, Takahiro Shimizu, Ryosuke Doijiri, Eriko Yamaguchi, Muneaki Kikuno, Yoshiaki Shimada, Hidehiro Takekawa, Masatoshi Koga, Masafumi Ihara, Koichi Hirata, Yasuhiro Hasegawa, Kazunori Toyoda Source Type: research

Commentary: Physical activity after patent foramen ovale (PFO)-associated stroke: a personal narrative and call to action
Top Stroke Rehabil. 2022 Jan 20:1-5. doi: 10.1080/10749357.2021.2021729. Online ahead of print.NO ABSTRACTPMID:35045804 | DOI:10.1080/10749357.2021.2021729
Source: Topics in Stroke Rehabilitation - January 20, 2022 Category: Neurology Authors: Jeff K Vallance I Hale G Hansen Source Type: research

Simultaneously Occurring Ischemic Stroke, Leg Artery Occlusion, and Pulmonary Embolism Induced by a Uterine Myoma
Paradoxical embolism from venous thrombosis through the patent foramen ovale is a rare but well-known cause of stroke in young adults. Here, we report a case of simultaneous middle cerebral artery infarction, multiple occlusions of the leg arteries, and pulmonary thromboembolism from the venous thrombus, all due to compression of the external iliac vein by a uterine leiomyoma.
Source: Journal of Stroke and Cerebrovascular Diseases - February 3, 2022 Category: Neurology Authors: Jean Hee Kim, Jaseong Koo, Kijeong Lee Tags: Case Report Source Type: research

Ipsilateral Carotid Plaque Presence is Inversely Associated with Patent Foramen Ovale in Cryptogenic Stroke: A Multicenter CohortStudy
Embolic stroke of undetermined source (ESUS) accounts for up to  20% of all strokes. Potential contributors to ESUS include patent foramen ovale (PFO) and non-stenotic plaque (
Source: Journal of Stroke and Cerebrovascular Diseases - June 21, 2022 Category: Neurology Authors: Anvitha Sathya, Thanh N. Nguyen, Sahily Reyes-Esteves, Scott Kamen, Taryn Hester, Nicholas Vigilante, John Woo, Linda Zhang, Mohamad Abdalkader, Brett Cucchiara, James E. Siegler Tags: Short Communication Source Type: research

Diagnosis of atrial fibrillation in young patients with ischemic stroke: A systematic review and meta-analysis
The recommended cardiac rhythm evaluation to determine the etiology of ischemic stroke (IS) is similar in all patients regardless of their age and includes an electrocardiogram and at least a 24-hour heart rhythm monitoring. However, it is known that the main causes of IS vary according to patients ’ age. There is a higher preponderance of arterial dissections and patent foramen ovale in younger patients, while atrial fibrillation (AF) is more common in older patients.
Source: Journal of Stroke and Cerebrovascular Diseases - August 30, 2023 Category: Neurology Authors: Joana V ítor, Gonçalo V. Bonifácio, Ana Catarina Fonseca Source Type: research

Propensity Score-Matched Analysis of Lesion Patterns in Stroke Patients With Patent Foramen Ovale and Patients With Spontaneous Intracranial Artery Dissection
Conclusion: The present study suggests that lesion patterns observed from DWI of patients with PFO and SIAD might provide clues to the etiology of infarcts. Single lesions (cortical or subcortical) might be a typical feature of PFO associated strokes, while multiple lesions in one vascular territory might be a specific feature of SIAD associated strokes. Introduction Both patent foramen ovale (PFO) and spontaneous intracranial artery dissection (SIAD) are important stroke risk factors, especially in young and middle-aged adults (1–3). About 25% of patients with ischemic stroke are cryptogenic (4), and PFO is ...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Closure versus medical therapy for preventing recurrent stroke in patients with patent foramen ovale and a history of cryptogenic stroke or transient ischemic attack.
CONCLUSIONS: The combined data from recent RCTs have shown no statistically significant differences between TDC and medical therapy in the prevention of recurrent ischemic stroke. TDC closure was associated with an increased risk of atrial fibrillation but not with serious adverse events. PMID: 26346232 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - September 8, 2015 Category: Journals (General) Authors: Li J, Liu J, Liu M, Zhang S, Hao Z, Zhang J, Zhang C Tags: Cochrane Database Syst Rev Source Type: research

Cryptogenic Stroke: Diagnostic Workup and Management
AbstractPurpose of reviewCryptogenic stroke describes a subset of ischemic stroke for which no cause can be found despite a structured investigation. There are a number of putative mechanisms of cryptogenic ischemic stroke including a covert structural cardiac lesion, paroxysmal atrial fibrillation, hypercoagulable state or undiagnosed malignancy. Because many of these proposed mechanisms are embolic – and based on studies of thrombus history showing commonalities between thrombus composition between cardioembolic and cryptogenic strokes – the concept of embolic stroke of undetermined source (ESUS) (Hart et al. Lancet ...
Source: Current Treatment Options in Cardiovascular Medicine - December 2, 2019 Category: Cardiology Source Type: research

Body Mass Index and Stroke Subtype in a Young Adult Stroke Population (I12-5D)
CONCLUSIONS: In our group of young adult stroke patients, we found the highest BMI in the group with intracranial atherosclerosis. Although this group represented a small number of patients, this young adult population is at increased risk for future strokes. It is important to educate them on lifestyle modifications such as weight loss and exercise in addition to the treatment of hypertension, diabetes mellitus and hyperlipidemia.Disclosure: Dr. Youn has nothing to disclose. Dr. Aung has nothing to disclose. Dr. Afrasiabi has nothing to disclose. Dr. Clark has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Youn, J., Aung, T., Afrasiabi, M., Clark, J. Tags: Obesity and Neurological Disorders Poster Presentations Source Type: research

Device used to close small hole in heart may protect against recurrent stroke
A device used to close a small hole in the heart may benefit certain stroke patients by providing an extra layer of protection for those facing years of ongoing stroke risk, according to the results of a large clinical trial led by UCLA researchers.“It is a major new treatment option for some people,” said Dr. Jeffrey Saver, director of theUCLA Comprehensive Stroke Center and lead author of the study. However, he added, “Using the device is going to have to be a considered clinical decision between the doctor and the patient about who’s the right person to get it.”Thefindings appear in the Sept. 14 New England Jo...
Source: UCLA Newsroom: Health Sciences - September 14, 2017 Category: Universities & Medical Training Source Type: news

Inherited Thrombophilia and the Risk of Arterial Ischemic Stroke: A Systematic Review and Meta-Analysis
Conclusions: Our results suggest that inherited thrombophilias including FVL, PTM, PCD, and PSD are associated with an increased risk of arterial ischemic stroke, particularly in young patients. The association with FVL and PTM is stronger in the homozygous than in the heterozygous state, suggesting a potential dose-response relationship and causal role for inherited thrombophilias. The implications of these findings with respect to the evaluation and management of patients with ischemic stroke require further investigation.DisclosuresCrowther: Alnylam: Equity Ownership; Daiichi Sankyo: Membership on an entity's Board of D...
Source: Blood - November 21, 2018 Category: Hematology Authors: Chiasakul, T., De Jesus, E., Tong, J., Chen, Y., Crowther, M., Garcia, D. A., Chai-Adisaksopha, C., Messe, S. R., Cuker, A. Tags: 331. Pathophysiology of Thrombosis: Poster II Source Type: research

Imaging Characteristics of Ischemic Strokes Related to Patent Foramen Ovale Clinical Sciences
Conclusions— A PFO-stroke usually appears as a single cortical or multiple small ischemic lesions in the vertebrobasilar circulation without any visible vessel occlusion on angiography. The recanalization rate is significantly lower than in AF-stroke. These imaging characteristics of PFO-stroke may help to diagnose the mechanism and determine the treatment strategy.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Kim, B. J., Sohn, H., Sun, B. J., Song, J.-K., Kang, D.-W., Kim, J. S., Kwon, S. U. Tags: Pediatric and congenital heart disease, including cardiovascular surgery, Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

A Case of Multiple Recurrent Ischemic Stroke in a Patient with Cholangiocarcinoma and Initiation of Anticoagulation Therapy for Secondary Stroke Prevention (P4.342)
CONCLUSIONS: Initiation of anticoagulation therapy and the optimal medications for secondary stroke prevention in cancer associated stroke remain controversial. Further randomized prospective studies are needed to establish treatment guidelines.Disclosure: Dr. Cheng has nothing to disclose. Dr. Then has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Cheng, J. Z., Then, R. Tags: Cerebrovascular Case Reports Source Type: research

Stroke and migraine is there a possible comorbidity?
In conclusion the association between migraine and stroke remains an open question. Solving the above mentioned issues is fundamental to understand the epidemiologic, pathogenetic and clinical aspects of migraine-related stroke.
Source: Italian Journal of Pediatrics - April 25, 2016 Category: Pediatrics Source Type: research