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Condition: Patent Foramen Ovale

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Total 1415 results found since Jan 2013.

The coexistence of a patent foramen ovale and obstructive sleep apnea may increase the risk of wake-up stroke in young adults.
CONCLUSIONS: These suggest that coexistence of PFO and OSA may associate with a greater risk of youth stroke. Decrease risk of stroke might occur if treating with CPAP in patients with OSA. PMID: 31045524 [PubMed - as supplied by publisher]
Source: Technology and Health Care - April 23, 2019 Category: Medical Devices Authors: Man H, Xu Y, Zhao Z, Zhang S, Lv R, Chi X, Li X, Zhang Z Tags: Technol Health Care Source Type: research

Who benefits from percutaneous closure of patent foramen ovale vs medical therapy for stroke prevention? In-depth and updated meta-analysis of randomized trials.
CONCLUSION: In certain groups of patients presenting with stroke, PFOC is beneficial in preventing future stroke compared to medical therapy. PMID: 31110604 [PubMed]
Source: World Journal of Cardiology - April 25, 2019 Category: Cardiology Authors: Dahal K, Yousuf A, Watti H, Liang B, Sharma S, Rijal J, Katikaneni P, Modi K, Tandon N, Azrin M, Lee J Tags: World J Cardiol Source Type: research

Patent Foramen Ovale in Cryptogenic Ischemic Stroke: Direct Cause, Risk Factor, or Incidental Finding?
Patent foramen ovale (PFO) has been associated with cryptogenic stroke. There is conflicting data and it remains uncertain whether PFO is the direct cause, a risk factor or an incidental finding. Potential stroke mechanisms include paradoxical embolism from a venous clot which traverses the PFO, in situ clot formation within the PFO, and atrial arrhythmias due to electrical signaling disruption. Main risk factors linked with PFO-attributable strokes are young age, PFO size, right-to-left shunt degree, PFO morphology, presence of atrial septal aneurysm, intrinsic coagulation-anticoagulation systems imbalance, and co-existen...
Source: Frontiers in Neurology - June 24, 2020 Category: Neurology Source Type: research

Oral anticoagulants vs antiplatelets in cryptogenic stroke with potential cardiac emboli: Meta-analysis
CONCLUSIONS: OACs compared with antiplatelet therapies were associated with a reduced recurrent ischemic stroke risk and OACs might be a viable non-procedural alternative in patients with cryptogenic stroke and potential cardiac emboli.PMID:34419310 | DOI:10.1016/j.ejim.2021.08.002
Source: European Journal of Internal Medicine - August 22, 2021 Category: Internal Medicine Authors: Wen-Yi Huang Bruce Ovbiagele Meng Lee Source Type: research

Assessment of patients with a suspected cardioembolic ischemic stroke. A national consensus statement
Conclusions: A primary neurological and neuroradiological assessment is mandatory and neurovascular specialists should manage the initiation of secondary prophylactic treatment. If a cardioembolic stroke is suspected, a dedicated cardiologist experienced in the management of cardioembolism should provide a tailored clinical and echocardiographic assessment.PMID:34470566 | DOI:10.1080/14017431.2021.1973085
Source: Scandinavian Cardiovascular Journal - September 2, 2021 Category: Cardiology Authors: Mark Aplin Asger Andersen Axel Brandes Helena Dominguez Jordi S Dahl Dorte Damgaard Helle K Iversen Kasper K Iversen Edith Nielsen Niels Risum Michael R Schmidt Niels H Andersen Source Type: research

24-hour ambulatory blood pressure and cryptogenic ischemic stroke in young adults
CONCLUSIONS: Non-dipping patterns of BP were associated with CIS in the absence of a PFO but not in the absence of hypertension. This may reflect differing pathophysiology underlying CIS in patients with versus without a PFO. Due to limitations of the study, results regarding absolute ABP levels should be interpreted with caution.Key MessagesNocturnal non-dipping patterns of blood pressure were associated with cryptogenic ischemic stroke except in participants with a patent foramen ovale and in those without hypertension by any definition, which may indicate differing pathophysiology underlying cryptogenic ischemic stroke ...
Source: Annals of Medicine - April 23, 2023 Category: Internal Medicine Authors: Lauri Tulkki Nicolas Martinez-Majander Petri Haapalahti Heli Tolppanen Juha Sinisalo Olli Repo Tomi Sarkanen Heikki Numminen Essi Ry ödi Pauli Ylikotila Risto O Roine Riikka Lautam äki Antti Saraste Tuuli Miettinen Jaana Autere Pekka J äkälä Marja He Source Type: research

Percutaneous closure of patent foramen ovale for cryptogenic stroke: A meta-analysis of randomized controlled trials
Conclusions: Currently-available randomized data do not support the use of percutaneous PFO closure for secondary stroke prevention in patients with cryptogenic stroke and PFO. An updated meta-analysis including further data from ongoing RCTs is warranted.
Source: International Journal of Cardiology - July 26, 2013 Category: Cardiology Authors: Joey S.W. Kwong, Yat-Yin Lam, Cheuk-Man Yu Tags: Original Articles Source Type: research

Transcatheter patent foramen ovale closure versus medical therapy for cryptogenic stroke: a meta-analysis of randomized clinical trials
Conclusions: In this meta-analysis, using intention-to-treat analysis, transcatheter device closure of PFO was not superior to standard medical therapy in the secondary prevention of cryptogenic stroke. Transcatheter closure was superior using per-protocol analysis.
Source: BMC Cardiovascular Disorders - December 11, 2013 Category: Cardiology Authors: Irbaz RiazAbhijeet DhobleAhmad MizyedPaul HsuMuhammad HusnainJustin LeeKapildeo LotunKwan Lee Source Type: research

Stroke prevention by percutaneous closure of patent foramen ovale: a systematic review and meta-analysis
Conclusions Percutaneous closure of PFO in patients with cryptogenic stroke does not appear superior to medical therapy according to currently available randomised data. Furthermore, it is associated with an increased incidence of atrial fibrillation. However, there are signals pointing towards a potential benefit and more research should be strongly encouraged.
Source: Heart - February 10, 2014 Category: Cardiology Authors: Wolfrum, M., Froehlich, G. M., Knapp, G., Casaubon, L. K., DiNicolantonio, J. J., Lansky, A. J., Meier, P. Tags: Drugs: cardiovascular system, Epidemiology Aortic and vascular disease Source Type: research

A systematic review of closure versus medical therapy for preventing recurrent stroke in patients with patent foramen ovale and cryptogenic stroke or transient ischemic attack
Abstract: The optimal treatment for secondary prevention in patients who have a patent foramen ovale (PFO) and history of cryptogenic stroke is still uncertain and controversial. In view of this, we performed a systematic review of randomized controlled trials (RCTs) to investigate whether PFO closure was superior to medical therapy for prevention of recurrent stroke or transient ischemic attack (TIA) in patients with PFO after cryptogenic stroke. We searched the Cochrane Central Register of Controlled Trials, Embase, PubMed, Web of Science, and ClinicalTrials.gov. Three randomized controlled trials with a total of 2303 pa...
Source: Journal of the Neurological Sciences - December 2, 2013 Category: Neurology Authors: Linkun Chen, Shuguang Luo, Lingwan Yan, Weijia Zhao Tags: Review Source Type: research

Prevalence of migraine headache in an in‐patient stroke population
ConclusionsThe prevalence of migraine in this hospital‐based stroke cohort was comparable to the estimated prevalence of migraine usually described in population studies. In our study population, the prevalence of migraine with aura was higher than expected. The increased prevalence of PFO in patients with migraine headache corresponds well to previous population studies.
Source: Acta Neurologica Scandinavica - October 23, 2014 Category: Neurology Authors: M. Lantz, K. Kostulas, E. Waldenlind, C. Sjöstrand Tags: Original Article Source Type: research

Value of Eye Movement Exam in Aiding Precise Localization in Stroke (P1.016)
We present an unusual presentation of midbrain stroke presenting with bilateral ptosis in an African American male with vascular risk factors and concurrent use of bevacizumab. This case illustrates how detailed knowledge of anatomy and detailed neurologic exam remain valuable tools for localizing and diagnosing subtle presentations of common neurologic disease. Case description: A 69 year-old African American man with vascular risk factors including hypertension, hyperlipidemia and poorly controlled diabetes experienced sudden onset horizontal diplopia associated with fatigue. The patient presented to the Emergency Depart...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Khandker, N., Schmerler, D., Mahajan, S., Serra, A., Strbian, D. Tags: Cerebrovascular Disease and Interventional Neurology I ePosters Source Type: research