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Condition: Patent Foramen Ovale
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Total 1415 results found since Jan 2013.
Prior Stroke in PFO Patients Is Associated With Both PFO-Related and -Unrelated Factors
Conclusion: In patients with CS and PFO, the likelihood of prior stroke is associated with both, PFO-related and PFO-unrelated factors.
Source: Frontiers in Neurology - June 3, 2020 Category: Neurology Source Type: research
Routine surveillance of pelvic and lower extremity deep vein thrombosis in stroke patients with patent foramen ovale
AbstractPatent foramen ovale (PFO) is a potential conduit for paradoxical embolization to the systemic atrial circulation of a thrombus originating in the venous system. In a selected group of subjects, the prevalence of deep vein thrombosis (DVT) was assessed. Subjects were identified if they underwent magnetic resonance venography (MRV) pelvis and lower extremity doppler (LE-VDU) for assessment of DVT with PFO. The primary outcome measure was to report the number of patients with paradoxical embolization as their suspected etiology of stroke due to the presence of DVT, which then will be considered as determined stroke. ...
Source: Journal of Thrombosis and Thrombolysis - September 3, 2020 Category: Hematology Source Type: research
Advances in the Diagnosis and Treatment of Pediatric Arterial Ischemic Stroke
AbstractThough rare, stroke in infants and children is an important cause of mortality and chronic morbidity in the pediatric population. Neuroimaging advances and implementation of pediatric stroke care protocols have led to the ability to rapidly diagnose stroke and in many cases determine the stroke etiology. Though data on efficacy of hyperacute therapies, such as intravenous thrombolysis and mechanical thrombectomy, in pediatric stroke are limited, feasibility and safety data are mounting and support careful consideration of these treatments for childhood stroke. Recent therapeutic advances allow for targeted stroke p...
Source: Neurotherapeutics - April 18, 2023 Category: Neurology Source Type: research
Synthetic Cannabis and Acute Ischemic Stroke (P6.259)
CONCLUSIONS:These cases introduce a previously unreported association between synthetic cannabis use and ischemic stroke in young adults. Our two cases had risk factors for ischemic stroke but were otherwise young and healthy and the onset of their deficits occurred within hours after first-time exposure to synthetic cannabis. Synthetic cannabis use is an important consideration in the investigation of stroke in young adults.Disclosure: Dr. Bernson-Leung has nothing to disclose. Dr. Leung has nothing to disclose. Dr. Kumar has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Bernson-Leung, M., Leung, L., Kumar, S. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research
Spreading Depolarization May Link Migraine and Stroke
Migraine increases the risk of stroke, particularly in young and otherwise healthy adults. Being the most frequent neurological condition, migraine prevalence is on a par with that of other common stroke risk factors, such as diabetes or hypertension. Several patterns of association have emerged: (1) migraine and stroke share a common association (eg, vasculopathies, patent foramen ovale, or pulmonary A‐V malformations); (2) injury to the arterial wall such as acute arterial dissections can present as migraine aura attacks or stroke; (3) strokes rarely develop during a migraine attack, as described for “migrainous stro...
Source: Headache: The Journal of Head and Face Pain - May 1, 2014 Category: Neurology Authors: Katharina Eikermann‐Haerter Tags: Review Article Source Type: research
Role of Occlusive Devices to Prevent Thromboembolism Among Persons With a Patent Foramen Ovale and Prior Stroke
Opinion statement
Patent foramen ovale (PFO) has been linked to stroke, presumably through the mechanism of paradoxical embolism; however, data is confusing regarding the causal relationship between PFO and embolic stroke. What has come to light in the past decade of research is that PFO closure with devices that achieve a high rate of closure may reduce the risk of recurrent stroke compared with medical therapy, but this benefit has not been shown in the general population with a PFO and cryptogenic stroke. The important question now is which patient will benefit from PFO closure for stroke risk reduction. A val...
Source: Current Treatment Options in Neurology - March 7, 2015 Category: Neurology Source Type: research
Diagnostic Yield of Venous Thrombosis and Pulmonary Embolism by Combined CT Venography and Pulmonary Angiography in Patients with Cryptogenic Stroke and Patent Foramen Ovale
Background: Paradoxical embolism via a patent foramen ovale (PFO) has been suggested as a potential stroke mechanism. Combined CT venography and pulmonary angiography (CVPA) is a simple, validated and accurate technique to diagnose deep venous thrombosis (DVT) or pulmonary embolism (PE). We sought to assess the prevalence of DVT or PE among patients with PFO and cryptogenic stroke (CS) by CVPA. Methods: Patients were identified retrospectively from a clinical registry of consecutive patients with stroke admitted to our Stroke Unit. The following criteria were required for inclusion in this study: CS, PFO identified by tran...
Source: European Neurology - July 25, 2015 Category: Neurology Source Type: research
Cardioembolic Stroke
This article summarizes the different causes of cardioembolism and outlines current management guidelines.
Recent Findings: Since cardioembolic stroke is not a single disease entity, its diagnosis requires initial clinical suspicion and a comprehensive evaluation, including ECG, echocardiography, brain imaging, and cardiac monitoring. Atrial fibrillation is the most common cause of cardioembolic stroke, and anticoagulation is usually recommended. This article reviews risk stratification models to assist in the decision-making process and highlights the increased use of novel oral anticoagulants for stroke prevention in at...
Source: CONTINUUM: Lifelong Learning in Neurology - February 1, 2017 Category: Neurology Tags: Review Articles Source Type: research
Ischemic Stroke in Young Adults: Profile of SARAH Hospital Brasília From 2008 to 2012
Conclusions: Etiological diagnosis of stroke in the young is challenging for clinicians. Hence, a more effective classification scheme, better investigative mechanisms, and correct determination of causal associations in ischemic stroke are needed. Thrombophilia screening should be performed in the presence of relevant clinical signs and/or family history.
Source: The Neurologist - March 1, 2017 Category: Neurology Tags: Original Article Source Type: research
Clinical Relevance of Patent Foramen Ovale and Atrial Septum Aneurysm in Stroke: Findings of a Single-Center Cross-Sectional Study
Conclusions: Our study indicates that a detected PFO +/ –ASA could exhibit a stroke-relevant finding, if classical risk factors for the stroke were lacking.Eur Neurol 2017;78:264 –269
Source: European Neurology - October 2, 2017 Category: Neurology Source Type: research
Percutaneous Closure Versus Medical Treatment in Stroke Patients With Patent Foramen Ovale: A Systematic Review and Meta-analysis.
Conclusion: Compared with medical treatment, PFO closure prevents recurrent stroke and TIA but increases the incidence of AF or AFL in PFO carriers with cryptogenic stroke.
Primary Funding Source: Italian Ministry of Education, University and Research (MIUR). (PROSPERO: CRD42017074686).
PMID: 29310133 [PubMed - as supplied by publisher]
Source: Annals of Internal Medicine - January 9, 2018 Category: Internal Medicine Authors: De Rosa S, Sievert H, Sabatino J, Polimeni A, Sorrentino S, Indolfi C Tags: Ann Intern Med Source Type: research
Cost-effectiveness of percutaneous patent foramen ovale closure as secondary stroke prevention.
CONCLUSIONS: Considering the UK healthcare system perspective, percutaneous PFO closure in cryptogenic ischemic stroke patients is a cost-effective stroke prevention strategy compared to medical therapy alone. Its cost-effectiveness was driven by substantial reduction in recurrent strokes and patients' improved health-related quality-of-life.
PMID: 29564942 [PubMed - as supplied by publisher]
Source: Journal of Medical Economics - March 23, 2018 Category: Health Management Tags: J Med Econ Source Type: research
A systematic review of the characteristics and prognosis of subjects who suffer an embolic stroke of undetermined source.
CONCLUSION: The application of the new ESUS criteria provides a better definition of patients with cryptogenic stroke. Applying the concept of ESUS requires not only adequate electrocardiogram monitoring, but also routine complementary examinations to rule out the presence of minor sources of cardioembolism and other sources of embolism other than atrial fibrillation.
PMID: 29749592 [PubMed - in process]
Source: Revista de Neurologia - May 13, 2018 Category: Neurology Authors: Molina-Seguin J, Vena AB, Colas-Campas L, Benalbdelhak I, Purroy F Tags: Rev Neurol Source Type: research
