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Condition: Patent Foramen Ovale

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Total 1415 results found since Jan 2013.

Frequency of Patent Foramen Ovale and Migraine in Patients With Cryptogenic Stroke Clinical Sciences
Conclusions—In patients with cryptogenic stroke who have migraine, there is a high prevalence (79%) of PFO with right-to-left shunt. The timing of the stroke in migraineurs is usually not related to a migraine attack. These observations are consistent with the hypothesis that the mechanism of stroke in migraineurs is most likely because of a paradoxical embolus. Future cryptogenic stroke classification schemes should consider including PFO as a separate etiologic category.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Brian H. West, Nabil Noureddin, Yakov Mamzhi, Christopher G. Low, Alexandra C. Coluzzi, Evan J. Shih, Rubine Gevorgyan Fleming, Jeffrey L. Saver, David S. Liebeskind, Andrew Charles, Jonathan M. Tobis Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke, Embolism Original Contributions Source Type: research

Neuroimaging Findings in Cryptogenic Stroke Patients With and Without Patent Foramen Ovale Clinical Sciences
Conclusions— This is the largest study to report the radiological characteristics of patients with cryptogenic stroke and known PFO status. Strokes that were large, radiologically apparent, superficially located, or unassociated with prior radiological infarcts were more likely to be PFO-associated than were unapparent, smaller, or deep strokes, and those accompanied by chronic infarcts. There was no association between PFO and multiple acute strokes nor between specific echocardiographic PFO features with neuroimaging findings.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Thaler, D. E., Ruthazer, R., Di Angelantonio, E., Di Tullio, M. R., Donovan, J. S., Elkind, M. S. V., Griffith, J., Homma, S., Jaigobin, C., Mas, J.-L., Mattle, H. P., Michel, P., Mono, M.-L., Nedeltchev, K., Papetti, F., Serena, J., Weimar, C., Kent, D. Tags: Cerebrovascular disease/stroke, Pediatric and congenital heart disease, including cardiovascular surgery, Computerized tomography and Magnetic Resonance Imaging, Risk Factors for Stroke Clinical Sciences Source Type: research

Endocarditis Is a Common Stroke Mechanism in Hemodialysis Patients Brief Reports
Conclusions— Cardioembolism and cryptogenic stroke are the predominant stroke mechanisms among hemodialysis patients. Infective endocarditis was identified frequently relative to other stroke cohorts, and a raised index of suspicion is warranted in the hemodialysis population.
Source: Stroke - March 24, 2014 Category: Neurology Authors: Ishida, K., Brown, M. G., Weiner, M., Kobrin, S., Kasner, S. E., Messe, S. R. Tags: Echocardiography, Embolic stroke Brief Reports Source Type: research

Patent Foramen Ovale and Cryptogenic Stroke: The Hole Story Emerging Therapy Critiques
Despite 3 recent randomized clinical trials, the management of patients with cryptogenic stroke and patent foramen ovale remains unsettled. The primary results of Evaluation of the STARFlex Septal Closure System in Patients with a Stroke and/or Transient Ischemic Attack due to Presumed Paradoxical Embolism Through a Patent Foramen Ovale (CLOSURE), Percutaneous Closure of Patent Foramen Ovale in Cryptogenic Stroke (PC), and Randomized Evaluation of Recurrent Stroke Comparing PFO Closure to Established Current Standard of Care Treatment (RESPECT) were the same; the intent to treat analysis for the primary end point in all 3 ...
Source: Stroke - August 26, 2013 Category: Neurology Authors: Furlan, A. J., Jauss, M. Tags: Other Stroke Treatment - Medical, Other Stroke Emerging Therapy Critiques Source Type: research

Diagnostic Yield of Pelvic Magnetic Resonance Venography in Patients With Cryptogenic Stroke and Patent Foramen Ovale Clinical Sciences
Conclusions— Among patients with ischemic stroke/transient ischemic attack and patent foramen ovale, the majority of detected DVTs were in LE veins rather than the pelvic veins and did not differ by stroke subtype. The routine inclusion of pelvic magnetic resonance venography in the diagnostic evaluation of CS warrants further prospective investigation.
Source: Stroke - July 28, 2014 Category: Neurology Authors: Liberman, A. L., Daruwalla, V. J., Collins, J. D., Maas, M. B., Botelho, M. P. F., Ayache, J. B., Carr, J., Ruff, I., Bernstein, R. A., Alberts, M. J., Prabhakaran, S. Tags: Deep vein thrombosis, Other diagnostic testing, Acute Cerebral Infarction, Embolic stroke Clinical Sciences Source Type: research

Closure of Patent Foramen Ovale Versus Medical Therapy in Patients With Cryptogenic Stroke or Transient Ischemic Attack Clinical Sciences
Conclusions—In patients with cryptogenic stroke/TIA and PFO who have their PFO closed, ischemic stroke recurrence is less frequent compared with patients receiving medical treatment. Atrial fibrillation is more frequent but mostly transient. There is no difference in TIA, all-cause mortality, or myocardial infarction.
Source: Stroke - January 22, 2018 Category: Neurology Authors: George Ntaios, Vasileios Papavasileiou, Dimitrios Sagris, Konstantinos Makaritsis, Konstantinos Vemmos, Thorsten Steiner, Patrik Michel Tags: Ischemic Stroke Original Contributions Source Type: research

Cost-Effectiveness of Patent Foramen Ovale Closure Versus Medical Therapy for Secondary Stroke Prevention Clinical Sciences
Conclusions—PFO closure for cryptogenic strokes in the right setting is cost-effective, producing benefit in QALYs gained and potential cost savings. However, patient selection remains vitally important as marginal declines in treatment effectiveness can dramatically affect cost-effectiveness.
Source: Stroke - May 25, 2018 Category: Neurology Authors: Michelle H. Leppert, Sharon N. Poisson, John D. Carroll, David E. Thaler, Chong H. Kim, Karen D. Orjuela, P. Michael Ho, James F. Burke, Jonathan D. Campbell Tags: Treatment, Cost-Effectiveness, Ischemic Stroke, Embolism Original Contributions Source Type: research

Fibrinolytic activity and platelet function in subjects with obstructive sleep apnoea and a patent foramen ovale: is there an option for prevention of ischaemic stroke?
Authors: Reggiani M, Karttunen V, Wartiovaara-Kautto U, Riutta A, Uchiyama S, Hillbom M Abstract Obstructive sleep apnoea (OSA) carries an increased risk of ischaemic stroke, but the underlying mechanism is not clear. As right-to-left shunting can occur through a patent foramen ovale (PFO) during periods of apnoea, we investigated nocturnal changes in fibrinolytic activity and platelet function in subjects who had OSA with or without PFO and in controls. We determined plasminogen activator inhibitor 1 (PAI-1) activity and antigen and platelet activation parameters. The severity of OSA was verified by polygraphy and...
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research

Stroke in the Young: Etiologies and Risk Factors (P7.124)
CONCLUSIONS: Stroke in the young shares many of the same common modifiable risk factors as stroke in the elderly including hypertension, hyperlipidemia, diabetes, and tobacco abuse. Other unique disease processes also contribute to stroke in this age group, often less modifiable. Given the devastating morbidity and mortality of stroke in this age group, a larger public health effort for primary and secondary prevention of stroke in the young should be aggressively pursued.Disclosure: Dr. Govind has nothing to disclose. Dr. Ahad has nothing to disclose. Dr. Iftekhar has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Govind, P., Ahad, R., Iftekhar, A. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke in Young Source Type: research

Body Mass Index and Stroke Subtype in a Young Adult Stroke Population (P7.126)
CONCLUSIONS: In our group of young adult stroke patients, we found the highest BMI in the group with intracranial atherosclerosis. Although this group represented a small number of patients, this young adult population is at increased risk for future strokes. It is important to educate them on lifestyle modifications such as weight loss and exercise in addition to the treatment of hypertension, diabetes mellitus and hyperlipidemia.Disclosure: Dr. Youn has nothing to disclose. Dr. Aung has nothing to disclose. Dr. Afrasiabi has nothing to disclose. Dr. Clark has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Youn, J., Aung, T., Afrasiabi, M., Clark, J. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke in Young Source Type: research

Patent Foramen Ovale, Subclinical Cerebrovascular Disease, and Ischemic Stroke in a Population-Based Cohort
Conclusions: In this community-based cohort, PFO was not associated with an increased risk of clinical stroke or subclinical cerebrovascular disease.
Source: Journal of the American College of Cardiology - May 3, 2013 Category: Cardiology Authors: Marco R. Di Tullio, Zhezhen Jin, Cesare Russo, Mitchell S.V. Elkind, Tatjana Rundek, Mitsuhiro Yoshita, Charles DeCarli, Clinton B. Wright, Shunichi Homma, Ralph L. Sacco Tags: Patent Foramen Ovale and Stroke Source Type: research

An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke
Conclusion: Clinical characteristics identify CS patients who vary markedly in PFO prevalence, reflecting clinically important variation in the probability that a discovered PFO is likely to be stroke-related vs incidental. Patients in strata more likely to have stroke-related PFOs have lower recurrence risk.
Source: Neurology - August 12, 2013 Category: Neurology Authors: Kent, D. M., Ruthazer, R., Weimar, C., Mas, J.-L., Serena, J., Homma, S., Di Angelantonio, E., Di Tullio, M. R., Lutz, J. S., Elkind, M. S. V., Griffith, J., Jaigobin, C., Mattle, H. P., Michel, P., Mono, M.-L., Nedeltchev, K., Papetti, F., Thaler, D. E. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Risk factors in epidemiology ARTICLE Source Type: research

Risk Factor and Etiology Analysis of Ischemic Stroke in Young Adult Patients
Conclusions: Traditional vascular risk factors are also very common in young adults with ischemic stroke, but such factors increase the susceptibility to stroke dependent to other causes as atherosclerosis and small-artery occlusion represent less than 20% of cases. Prognosis quoadvitam is good, being characterized by low mortality and recurrence rate.
Source: Journal of Stroke and Cerebrovascular Diseases - January 13, 2014 Category: Neurology Authors: Rosaria Renna, Fabio Pilato, Paolo Profice, Giacomo Della Marca, Aldobrando Broccolini, Roberta Morosetti, Giovanni Frisullo, Elena Rossi, Valerio De Stefano, Vincenzo Di Lazzaro Tags: Original Articles Source Type: research

Paroxysmal Atrial Fibrillation Detection Rates In Cryptogenic Stroke Patients Selected By Stroke Specialists For Prolonged Cardiac Monitoring (P1.053)
CONCLUSION: Long term cardiac monitoring with ICM has a very high yield of detecting PAF in cryptogenic stroke patients when selected by a stroke expert.Disclosure: Dr. Salahuddin has nothing to disclose. Dr. Zaidi has nothing to disclose. Dr. Tietjen holds stock and/or stock options in Johnson & Johnson and Stryker. Dr. Cummings has nothing to disclose. Dr. Jumaa has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Salahuddin, H., Zaidi, S., Tietjen, G., Cummings, J., Jumaa, M. Tags: Cerebrovascular Disease and Interventional Neurology: Atrial Fibrillation and Cardio-embolic Stroke Source Type: research

Migraine Improves after Ischemic Stroke
Objective: To assess if migraine frequency spontaneously changes after stroke.Background: Patent foramen ovale (PFO) closure has been reported to decrease migraine attacks. Because many closures are carried out after an ischemic stroke, it is possible that migraine spontaneously improves after stroke.Methods: We have prospectively collected all patients with ischemic stroke and active migraine admitted to our stroke unit and have compared their migraine frequency before and 6, 12, and 24 months after stroke.Results: We studied 43 patients. Mean follow-up was 1.3 ± .5 years. The mean number of migraine attacks per month de...
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2013 Category: Neurology Authors: Bruno Censori, Tania Partziguian, Marco Poloni Tags: Original Articles Source Type: research