[Use of the Montreal Cognitive Assessment (MoCA) in Latin America: a systematic review].
CONCLUSIONS: The small number of articles identified may reflect a late start of the use of MoCA in Latin America. A tendency towards the use of this test without making a cross-cultural adaptation and the use of international norms was observed in this region. The present systematic review demonstrates the need for future research tackling the development of a linguistically adapted version of the MoCA to Latin America and the study of its psychometric properties, with the aim of improving cognitive assessment. PMID: 29897607 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - June 14, 2018 Category: Neurology Authors: Loureiro C, Garcia C, Adana L, Yacelga T, Rodriguez-Lorenzana A, Maruta C Tags: Rev Neurol Source Type: research

[Psychomotor development in patients with severe congenital heart disease].
CONCLUSIONS: Psychomotor development delay, especially in the area of language, is more frequent in patients with severe congenital heart disease. The presence of cyanosis and the need for extracorporeal membrane oxygenation were the variables that are most associated with this type of pathology. PMID: 29897608 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - June 14, 2018 Category: Neurology Authors: Salamanca-Zarzuela B, Morales-Luego F, Alcalde-Martin C, Centeno-Malfaz F Tags: Rev Neurol Source Type: research

[Caloric restriction and memory during aging].
CONCLUSIONS: Caloric restriction attenuates the normal or pathological aging of the brain and reduces age-related memory problems. Dietary intervention could become a very effective method to promote a better quality of life and prevent the age-related cognitive deficits. PMID: 29897609 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - June 14, 2018 Category: Neurology Authors: Marti-Nicolovius M, Arevalo-Garcia R Tags: Rev Neurol Source Type: research

Ocrelizumab: its efficacy and safety in multiple sclerosis.
CONCLUSIONS: Ocrelizumab is the first drug that has been shown to be able to significantly slow disability progression at 12 and 24 weeks in patients with PPMS. It is also effective in controlling clinical and radiological activity in patients with RRMS forms, and it is approved and indicated for both phenotypes of the disease. To date, the safety profile of ocrelizumab matches that observed in clinical trials, without any unexpected alerts. PMID: 29897610 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - June 14, 2018 Category: Neurology Authors: Juanatey A, Blanco-Garcia L, Tellez N Tags: Rev Neurol Source Type: research

[A rare early-onset dystonia (DYT16) in a Portuguese girl].
PMID: 29897611 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - June 14, 2018 Category: Neurology Authors: Almeida S, Rangel MA, Neiva C, Carrilho I, Leao M, Santos F, Vila Real M Tags: Rev Neurol Source Type: research

[Autoimmune encephalitis].
Abstract Autoimmune encephalitis are a new category of inflammatory diseases of the central nervous system mediated by antibodies that attack neurotransmitter or protein receptors on the surface of neurons. The clinical syndromes are complex and are associated with manifestations that vary according to the type of antibody that is associated. The autoimmune response can start due to the presence of a tumour or viral infection, but in many case the cause remains unknown. In paediatrics, the most frequent autoimmune encephalitis is that associated with NMDA glutamate receptor antibodies (or anti-NMDA encephalitis). ...
Source: Revista de Neurologia - June 5, 2018 Category: Neurology Authors: Guasp M, Arino H, Dalmau J Tags: Rev Neurol Source Type: research

[Transition from child to adult epilepsy. Difficulties with an objective that cannot be delayed].
Abstract Paediatric care of a chronic process is limited by the moment when the clinical and therapeutic follow-up must be continued by a specialist from the area for adults. The delay in the transition from paediatrics to adult medicine can be due to causes attributable to the patient or his/her relatives, or the professional who diagnosed the disease. The former arises from the uncertainty of facing the unknown, which becomes more intense when the diagnosis and treatment have been difficult, as there is a fear of upsetting the stability of the patient. The latter concerns the paediatric specialist, who created t...
Source: Revista de Neurologia - June 5, 2018 Category: Neurology Authors: Casas-Fernandez C, Alarcon-Martinez H, Martinez-Salcedo E, Ibanez-Mico S Tags: Rev Neurol Source Type: research

[Movement disorders].
This article offers a brief summary of these disorders and also includes a simple note, in honour of Dr Natalio Fejerman (1934-2018), on the so-called «benign polymorphic disorder of infancy». PMID: 29876907 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - June 5, 2018 Category: Neurology Authors: Fernandez-Alvarez E Tags: Rev Neurol Source Type: research

[Antiepileptic drugs].
We report the most notable pharmacokinetic and pharmacodynamic characteristics of the antiepileptic drugs commercialised in the last four years (eslicarbazepine acetate, brivaracetam and perampanel). Their efficacy and safety are analysed in open-label clinical trials, which are the ones that reproduce their use in everyday life, without the rigid protocols used in clinical trials. PMID: 29876908 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - June 5, 2018 Category: Neurology Authors: Herranz JL Tags: Rev Neurol Source Type: research

[Latest developments in ataxias].
This article reviews the advances made in the field of ataxias over the past four years. It concludes that there is no single spectacular finding like those that have taken place in the last 25 years and they can all be attributed to the remarkable evolution of genetics and neuroimaging. Nevertheless, algorithms have been perfected that allow a more rational use of the previous techniques to reach a correct diagnosis and possible treatment. With regard to the treatments proposed to alleviate the symptoms of ataxias, there is no unquestionable evidence leading us to think that the symptoms can be reverted with the means cur...
Source: Revista de Neurologia - June 5, 2018 Category: Neurology Authors: Prats-Vinas JM Tags: Rev Neurol Source Type: research

[Childhood headaches: new concepts and recent advances].
This study reports on the latest advances in childhood headaches that have been made in the last few years, with special emphasis on the important new modifications that have been produced with respect to the previous ones, published in the beta version of the third edition of the International Classification of Headache Disorders. These include headaches that have undergone important qualifications, the appearance of new entities and a section which reports the existence of new headaches, but which have still not been considered as new entities. Additionally, other points that are highlighted include the strong relation b...
Source: Revista de Neurologia - June 5, 2018 Category: Neurology Authors: Rufo-Campos M, Rufo-Munoz M Tags: Rev Neurol Source Type: research

[New insights in inborn errors of metabolism are leading to new paradigms in child neurology].
This article is a brief summary of the updated IEM classification combined with major neurological presentations in a tentative towards a pathophysiology based clinical practice in child neurology. In particular we emphasize a clinical approach focused in a continuum/spectrum of symptoms. PMID: 29876911 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - June 5, 2018 Category: Neurology Authors: Garcia-Cazorla A, Saudubray JM Tags: Rev Neurol Source Type: research

[Novel treatments in neurometabolic diseases: the importance of chaperones].
Abstract Incorrect protein folding has been related to a number of genetic diseases. In these pathologies, loss and gain of function mutations can cause protein instability, giving rise to alterations in their catalytic properties or in their subcellular location. The literature includes reports of a number of diseases, called conformational diseases, which are produced by mutations that affect folding. Therefore, many pathologies could benefit from treatment with certain drugs such as proteostasis regulators or pharmacologic chaperones. This work describes the potential use of pharmacologic chaperones in several ...
Source: Revista de Neurologia - June 5, 2018 Category: Neurology Authors: Perez B Tags: Rev Neurol Source Type: research

[Accompaniment and follow-up of children with severe neurological diseases. Care by a specialised paediatric palliative care team].
Abstract Paediatric palliative care is that given to children suffering from a disease that limits or threatens their life. It therefore covers a wide range of pathologies and clinical situations, among which neurological pathology occupies an especially prevalent and complex position that requires suitably coordinated, structured and multidisciplinary care. The aim of this article is to describe the specificities presented by patients with neurological diseases out of all the children who could benefit from palliative care, as well as the characteristics of the Paediatric Palliative Care Unit of the Sant Joan de ...
Source: Revista de Neurologia - June 5, 2018 Category: Neurology Authors: Porras-Cantarero JA, Gutierrez-Rada C, Palomares-Delgado M, Navarro-Marchena L, Navarro-Villarrubi S Tags: Rev Neurol Source Type: research

[Social and familial difficulties as a consequence of the neurological illness of a child: the perspective of health and social work].
Abstract When we speak of children with special needs, who require the aid of a number of professionals and who have a severe disability, it is necessary to have available a comprehensive group of different professionals (paediatrician, nurse, social worker, psychologist, etc.) who work together as a team. The specialist physician or doctor responsible for the sick child alone cannot take responsibility for all the psychosocial consequences that result from the neurological disease, which is a chronic illness that, generally speaking, means the families arrange their lives to revolve around the sick child. The set...
Source: Revista de Neurologia - June 5, 2018 Category: Neurology Authors: Gonzalez-Pena A Tags: Rev Neurol Source Type: research

[Psychological and spiritual needs of children with severe encephalopathy and their families].
This article reports on the psychological and spiritual needs of the family of a child suffering from a severe disease and receiving palliative care, as well as addressing aspects related to the way they cope with such circumstances. PMID: 29876915 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - June 5, 2018 Category: Neurology Authors: Del Rincon-Fernandez C Tags: Rev Neurol Source Type: research

[Neonatal onset of epileptic syndromes. Causations and diagnostic process].
Abstract Neonatal convulsions are the most frequent form of expression of neurological pathology in the neonatal period. They represent a neurological emergency and thus require urgent diagnosis and treatment, as they are associated with a high risk of neonatal mortality or adverse neurological prognosis. Most neonatal convulsions are symptomatic and secondary to an identifiable causation. The causes vary widely. In this review we describe the electroclinical and aetiological aspects, and we also analyse the process of diagnosing the main epileptic syndromes in newborn infants. The importance of their diagnosis is...
Source: Revista de Neurologia - June 5, 2018 Category: Neurology Authors: Fons-Estupina MC Tags: Rev Neurol Source Type: research

[XLI Reunion Anual de la Sociedad Espa ñola de Neurologia Pediatrica (SENEP). Communications].
[XLI Reunion Anual de la Sociedad Española de Neurologia Pediatrica (SENEP). Communications]. Rev Neurol. 2018 Jun 05;66(s02):S71-S331 Authors: PMID: 29876917 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - June 5, 2018 Category: Neurology Tags: Rev Neurol Source Type: research

[Social cognition and cognitive functions in patients with epilepsy treated with eslicarbazepine acetate].
CONCLUSION: Treatment with ESL could improve some aspects of theory of mind in patients with epilepsy, especially in men and independently of the control of seizures, with no changes in quality of life, anxiety or depression. PMID: 29790568 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - May 24, 2018 Category: Neurology Authors: Abraira L, Sanabria A, Ortega G, Quintana M, Santamarina E, Salas-Puig J, Toledo M Tags: Rev Neurol Source Type: research

[Laryngeal dystonia: novel forms of therapeutic administration of botulinum toxin by direct routes].
CONCLUSION: In our experience, transoral administration of botulinum toxin type A to treat laryngeal dystonia has proved to be a simple, quick, effective and safe technique. PMID: 29790569 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - May 24, 2018 Category: Neurology Authors: Lopez Del Val LJ, Sebastian-Cortes JM, Bellosta-Diago E, Santos-Lasaosa S, Vinueza-Buitron PR, Lois-Ortega Y, Valles-Varea H, Lopez-Garcia E Tags: Rev Neurol Source Type: research

[ «Man-in-the-barrel» syndrome: atypical manifestation of giant cell arteritis].
CONCLUSIONS: Although the typical clinical manifestations of giant cell arteritis are headache, jaw claudication, loss of sight, constitutional symptoms and polymyalgia rheumatica, its presence must be suspected in patients over the age of 50 who manifest alterations affecting the peripheral nerve, including brachial diplegia with no other demonstrable cause. PMID: 29790570 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - May 24, 2018 Category: Neurology Authors: Calle-Lopez Y, Fernandez-Ramirez AF, Franco-Dager E, Gomez-Lopera JG, Vanegas-Garcia AL Tags: Rev Neurol Source Type: research

[Epidemiology of Alzheimer's disease and other dementias].
CONCLUSIONS: The prevalence and incidence of dementia increase exponentially from the age of 65 onwards. As a consequence of the progressive ageing of the population and the increase in life expectancy, the number of cases of dementia will rise in the coming decades. Recent studies point to a slight drop in the accumulated risk of dementia adjusted by age groups and sex over the last few decades in some countries. It is possible that by means of primary prevention strategies implemented upon the known risk factors for dementia the burden of dementia on public health will diminish in the future. PMID: 29790571 [PubMed ...
Source: Revista de Neurologia - May 24, 2018 Category: Neurology Authors: Garre-Olmo J Tags: Rev Neurol Source Type: research

[Selective dorsal rhizotomy: a review of the literature on this technique for the treatment of spasticity in infantile cerebral palsy].
CONCLUSIONS: Following the literature review, we believe there is enough experience to state that selective dorsal rhizotomy is a safe and simple technique from which many patients with spasticity of the lower limbs secondary to infantile cerebral palsy can benefit in both the short and the long term. PMID: 29790572 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - May 24, 2018 Category: Neurology Authors: Garriz-Luis M, Sanchez-Carpintero R, Alegre M, Tejada S Tags: Rev Neurol Source Type: research

[Vitiligo with Koebner phenomenon in a patient with multiple sclerosis treated with alemtuzumab].
PMID: 29790573 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - May 24, 2018 Category: Neurology Authors: Eichau S, Lopez-Ruiz R, Ruiz-Pena JL, Paramo MD, Navarro-Mascarell G, Izquierdo G Tags: Rev Neurol Source Type: research

[A systematic review of the characteristics and prognosis of subjects who suffer an embolic stroke of undetermined source].
CONCLUSION: The application of the new ESUS criteria provides a better definition of patients with cryptogenic stroke. Applying the concept of ESUS requires not only adequate electrocardiogram monitoring, but also routine complementary examinations to rule out the presence of minor sources of cardioembolism and other sources of embolism other than atrial fibrillation. PMID: 29749592 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - May 13, 2018 Category: Neurology Authors: Molina-Seguin J, Vena AB, Colas-Campas L, Benalbdelhak I, Purroy F Tags: Rev Neurol Source Type: research

A cortical study of the attention in military simulation tests.
CONCLUSIONS: The results obtained show that the two groups studied do not behave homogeneously in the same attention task that involves a video game. PMID: 29749593 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - May 13, 2018 Category: Neurology Authors: Idiazabal-Alecha MA, Sebastian-Guerrero MV, Navascues-Sanagustin MA, Arcos-Sanchez C, Arana-Aritmendiz MV, Ruiz-Lopez C, Iso-Perez JM Tags: Rev Neurol Source Type: research

[Non-aneurysmal subarachnoid haemorrhage secondary to panarteritis nodosa at paediatric age: a case report].
CONCLUSIONS: The clinical features of polyarteritis nodosa together with continued anti-platelet therapy to prevent thromboembolic disease in this patient could have predisposed to the haemorrhagic event in the process of cerebral vasculitis. Standard subarachnoid haemorrhage management is initially required in such cases as cerebral aneurysms are the most common cause of haemorrhage in the context of polyarteritis nodosa disease. PMID: 29749594 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - May 13, 2018 Category: Neurology Authors: Salgado-Lopez L, de Quintana-Schmidt C, Catala-Antunez I, Aibar-Duran J, San Roman-Manzanera L, Molet-Teixido J Tags: Rev Neurol Source Type: research

[Virtual reality and dementia].
CONCLUSIONS: Virtual reality is a growing and very promising area for psychological intervention in general, and more particularly for the treatment of dementia. It seems to enjoy a very favourable acceptance among persons suffering from dementia. Nevertheless, it is important to understand the new technologies as a tool rather than as a substitute for the therapist. Likewise, there is a need for more rigorous and systematic research that determines the efficacy of this kind of intervention. PMID: 29749595 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - May 13, 2018 Category: Neurology Authors: Diaz-Perez E, Florez-Lozano JA Tags: Rev Neurol Source Type: research

[Jose Ingenieros and the amusias: the beginning of the neuropsychology in Argentina].
This article gave rise to this book in French on the musical language and its hysterical alterations awarded by the Academy of Medicine of Paris. PMID: 29749596 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - May 13, 2018 Category: Neurology Authors: Allegri RF, Roman FN Tags: Rev Neurol Source Type: research

[Nuclear paralysis of the oculomotor nerve within the context of traumatic brain injury].
PMID: 29749597 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - May 13, 2018 Category: Neurology Authors: Roman-Pena P, Aran-Echabe E, Raposo-Furelos M, Gelabert-Gonzalez M Tags: Rev Neurol Source Type: research

[Minor stroke in a patient with thrombocytopenia].
PMID: 29749598 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - May 13, 2018 Category: Neurology Authors: Gomez A, Garcia-Torres A, Rosas E, Llaguno M, Querejeta A, Navas-Vinagre I, Zamarbide-Capdepon I, Saez R, Arquero T, Villaescusa T, Vega G Tags: Rev Neurol Source Type: research

Influence of cognitive impairment on the freezing of gait in non demented people with Parkinson's disease.
CONCLUSION: Cognitive parameters may have an important contribution to the manifestation of freezing of gait in PD. These results may have important clinical implications for developing future non-pharmacological and cognitive interventions strategies targeted to PD patients with FOG. PMID: 29696615 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - April 28, 2018 Category: Neurology Authors: Cancela JM, Nascimento CM, Varela S, Seijo-Martinez M, Lorenzo-Lopez L, Millan-Calenti JC, Dominguez-Vivero C, Ayan C Tags: Rev Neurol Source Type: research

[Analysis of the quantitative differences in the thickness of the retinal nerve fibre layer between time-domain and spectral-domain optical coherence tomography in patients with relapsing-remitting multiple sclerosis].
CONCLUSIONS: There is a strong correlation between the two tomography scans in the measurement of the thickness of the RNFL in patients with MS, with and without a history of ON. Time-domain OCT quantifies greater thicknesses, and therefore both types of tomography have proven to be effective in the study of MS, although the results cannot be interchanged or extrapolated. PMID: 29696616 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - April 28, 2018 Category: Neurology Authors: Gonzalez-Gomez A, Garcia-Ben A, Soler-Garcia A, Garcia-Basterra I, Padilla-Parrado F, Garcia-Campos JM Tags: Rev Neurol Source Type: research

[Clinical and neuropsychological characteristics in congenital central hypoventilation syndrome].
CONCLUSIONS: The profile of functional impairment in the CCHS is variable: in case 1, a severe global developmental delay with autistic features and marked functional involvement is described. In case 2, bilateral atrophy of the hippocampus is associated with involvement in social cognition and in executive functions with moderate functional repercussion. Case 3 shows difficulties in some cognitive executive functions (planning and non-verbal fluency), but without functional repercussion. Neuropsychological assessment can help in the clinical management of these patients by determining and guiding the need for rehabilitati...
Source: Revista de Neurologia - April 28, 2018 Category: Neurology Authors: Seijas-Gomez R, Esteso-Orduna B, Melero-Llorente J, Fournier-Del Castillo MC Tags: Rev Neurol Source Type: research

[Epilepsy, Mozart and his sonata K.448: is the «Mozart effect» therapeutic?]
CONCLUSIONS: The «Mozart effect» has a scientific basis but its nature limits the methodological quality of the research. The music of Mozart, chosen for its exquisite structure, has been able to increase even more the controversy because also it is of the taste of a great majority. It is still far from being consolidated as a non-pharmacological antiepileptic treatment, but it could increase the scientific evidence with studies whose design minimizes the cited confounding factors. PMID: 29696618 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - April 28, 2018 Category: Neurology Authors: Hernando-Requejo V Tags: Rev Neurol Source Type: research

[Intraoperative neurophysiological monitoring in Spain: its beginnings, current situation and future prospects].
ratoria de la Senfc GTMNIS Abstract Intraoperative neurophysiological monitoring (IONM) is nowadays another tool within the operating room that seeks to avoid neurological sequels derived from the surgical act. The Spanish Neurophysiological Intra-Surgical Monitoring Association (AMINE) in collaboration with the Spanish Society of Clinical Neurophysiology (SENFC), and the IONM Working Group of the SENFC has been collecting data in order to know the current situation of the IONM in Spain by hospitals, autonomous communities including the autonomous cities of Ceuta and Melilla, the opinions of the specialists in cli...
Source: Revista de Neurologia - April 28, 2018 Category: Neurology Authors: Cortes-Donate VE, Perez-Lorensu PJ, Garcia-Garcia A, Asociacion de Monitorizacion Intraquirurgica Neurofisiologica Espanola Amine AMINEA, Sociedad Espanola de Neurofisiologia Clinica Senfc SENCS, Grupo de Trabajo de Monitorizacion Neurofisiologica Intraop Tags: Rev Neurol Source Type: research

[GNAO1: a new gene to consider on early-onset childhood dystonia].
PMID: 29696620 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - April 28, 2018 Category: Neurology Authors: Marecos C, Duarte S, Alonso I, Calado E, Moreira A Tags: Rev Neurol Source Type: research

[Reversible cerebral vasoconstriction syndrome following smoking cessation and treatment with bupropion].
PMID: 29696621 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - April 28, 2018 Category: Neurology Authors: De la Torre-Colmenero JD, Arjona-Padillo A, Fernandez-Perez J Tags: Rev Neurol Source Type: research

[Infantile epileptic encephalopathy: a good genetic study should be a priority].
PMID: 29696622 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - April 28, 2018 Category: Neurology Authors: Mayo S, Gomez-Manjon I, Moreno-Izquierdo A, Moreno-Garcia M, Fernandez-Martinez FJ Tags: Rev Neurol Source Type: research

[New drugs for the treatment of multiple sclerosis].
PMID: 29645067 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - April 14, 2018 Category: Neurology Authors: Rio J Tags: Rev Neurol Source Type: research

[Frequency, semiology and prognosis of benign infantile epilepsy].
CONCLUSIONS: Benign infantile epilepsy is a frequent epileptic syndrome. Semiology of seizures is not useful to characterize the syndrome. A diagnosis of benign infantile epilepsy at six month of evolution implies a reasonably good prognosis, but possibly not as good as for other self-limited epilepsies of infancy. PMID: 29645068 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - April 14, 2018 Category: Neurology Authors: Ramos-Lizana J, Martinez-Espinosa G, Rodriguez-Lucenilla MI, Aguirre-Rodriguez J, Aguilera-Lopez P Tags: Rev Neurol Source Type: research

[Childhood ischemic cerebrovascular disease in a paediatric emergency service: a descriptive study].
CONCLUSIONS: CVD is uncommon in pediatrics, but with a high morbimortality, so it is important to make an early diagnosis. Clinical and personal history are fundamental, nevertheless, we mainly deal with a previously healthy child without known risk factors at the time of the first evaluation. In case of clinical suspicion of stroke, a normal initial CT does not rule out a CVD, so other additional tests, such as MRI, are necessary. PMID: 29645069 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - April 14, 2018 Category: Neurology Authors: Garcia-Sanchez P, Lopez-Lopez R, Rubio-Gordon L, Rosich-Del Cacho B, Tesouro-Rodriguez L, Rivas-Paterna MA, Perez-Moneo Agapito MA, Garcia-Garcia S Tags: Rev Neurol Source Type: research

[Isolated girdle weakness: expansion of the phenotypic spectrum of the MERRF 8344A > G mutation of mitochondrial DNA].
CONCLUSIONS: The 8344A>G mutation of mitochondrial DNA can be associated with clinical signs and symptoms of adult-onset girdle weakness, and must therefore be included as part of its differential diagnosis. PMID: 29645070 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - April 14, 2018 Category: Neurology Authors: Erdocia-Goni A, Alonso-Jimenez A, Ramon-Carbajo C, Garcia-Arumi E, Casquero P, Gallardo E, Diaz-Manera J Tags: Rev Neurol Source Type: research

Daclizumab in multiple sclerosis.
CONCLUSIONS: Daclizumab has shown efficacy in slowing the inflammatory process of multiple sclerosis, although the appearance of potentially serious side effects has not allowed its use to significantly impact current clinical practice. The development of new drugs in multiple sclerosis must be contingent on maintaining or improving the risk-benefit profile with respect to those already in use. PMID: 29645071 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - April 14, 2018 Category: Neurology Authors: Perez-Miralles FC Tags: Rev Neurol Source Type: research

[XIX Reunion Anual de la Sociedad Extreme ña de Neurologia. Communications].
[XIX Reunion Anual de la Sociedad Extremeña de Neurologia. Communications]. Rev Neurol. 2018 Apr 16;66(8):283-285 Authors: PMID: 29645072 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - April 14, 2018 Category: Neurology Tags: Rev Neurol Source Type: research

[Optochiasmatic tuberculomas as a paradoxical reaction to treatment for meningeal tuberculosis].
PMID: 29645073 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - April 14, 2018 Category: Neurology Authors: Soto-Cabrera E, Villamil-Osorio LV, Garcia-Luna RC, Carrera-Pineda R Tags: Rev Neurol Source Type: research

[Microcephalies and Zika virus].
PMID: 29645074 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - April 14, 2018 Category: Neurology Authors: Meijides-Mejias C, Dorta-Contreras AJ Tags: Rev Neurol Source Type: research

[Mobile applications related to stroke: a systematic review].
CONCLUSIONS: Evidences with low methodological quality were identified in relation to different areas of care of the patient with stroke, as well as a wide range of applications in the different application markets, which advocated the creation of mechanisms of regulation regarding the validity of content. PMID: 29557547 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 24, 2018 Category: Neurology Authors: Rodriguez-Prunotto L, Cano-de-la-Cuerda R Tags: Rev Neurol Source Type: research

[The effects of moderate physical exercise on cognition in adults over 60 years of age].
CONCLUSIONS: The geriatric revitalisation programme can be a valuable tool for improving cognition in adults over 60 years of age, resulting in enhanced well-being in their quality of life. PMID: 29557548 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 24, 2018 Category: Neurology Authors: Sanchez-Gonzalez JL, Calvo-Arenillas JI, Sanchez-Rodriguez JL Tags: Rev Neurol Source Type: research

[X-linked adrenoleukodystrophy with an atypical radiological pattern].
CONCLUSIONS: Symmetrical demyelination with calcifications has rarely been reported in X-ALD, and these findings could delay diagnosis. This exceptional presentation should always be taken into consideration in children with subacute onset of motor symptoms and cognitive or behavioural regression. PMID: 29557549 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 24, 2018 Category: Neurology Authors: Ulate-Campos A, Petanas-Argemi J, Rebollo-Polo M, Jou C, Sierra C, Armstrong J, Fons-Estupina MC Tags: Rev Neurol Source Type: research