Chronology of Justo Gonzalo's research on brain dynamics
CONCLUSIONS: The theory of brain dynamics was established in two stages. The first (between 1938 and 1950) had an important clinical foundation, involving the observation of new phenomena and the formulation of new concepts. The second (between 1950 and 1960) included the introduction of more far-reaching concepts, such as the functional cortical gradient, and allometry laws based on a change of scale. Today, various authors believe that the concept of the gradient is crucial for understanding how the brain is organised.PMID:38502168 | DOI:10.33588/rn.7807.2024050 (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: A Garc ía-Molina I Gonzalo-Fonrodona Source Type: research

The p-value of the test is not a 'mathematical index', it is simply a relative frequency
Rev Neurol. 2024 Apr 1;78(7):209-211. doi: 10.33588/rn.7807.2023164.ABSTRACTLeading scientific journals in fields such as medicine, biology and sociology repeatedly publish articles and editorials claiming that a large percentage of doctors do not understand the basics of statistical analysis, which increases the risk of errors in interpreting data, makes them more vulnerable to misinformation and reduces the effectiveness of research. This problem extends throughout their careers and is largely due to the poor training they receive in statistics - a problem that is common in developed countries. As stated by H. Halle and ...
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: C Carazo-D íaz L Prieto-Valiente Source Type: research

RYR1 myopathies in childhood: phenotype-genotype correlation and incidence
CONCLUSIONS: RYR1-RM in our series exhibited phenotypic and involvement variability, with an incidence in our area of around 1 in 10,000 live births. Most cases were male, with dominant missense variants. We contribute five previously undescribed genetic variants.PMID:38502166 | DOI:10.33588/rn.7807.2023348 (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: N Del Arco-Guzm án S Lobato-L ópez R Calvo-Medina R Vera-Medialdea C Ruiz-P érez J M Ramos-Fern ández Source Type: research

Core data set for real world data in multiple sclerosis: customization for latin america from a global task force recommendation
CONCLUSION: The core data set seeks to harmonize the variables collected by registries and cohorts in MS in Latin America in order to facilitate said collection and allow collaboration between sources. Its implementation will facilitate real life data collection and collaboration in the region.PMID:38502167 | DOI:10.33588/rn.7807.2023326 (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: J I Rojas F Gracia T Parciak R Alonso J Becker I Trevi ño-Frenk M Alonso-Serena D Giunta P Abad E Carnero-Contentti A Carr á E P Correa-D íaz J Correale E Cristiano J Flores M Fruns L Galleguillos O Garcea F Hamuy M Lana-Peixoto C Navas R Pappais-Alvar Source Type: research

Chronology of Justo Gonzalo's research on brain dynamics
CONCLUSIONS: The theory of brain dynamics was established in two stages. The first (between 1938 and 1950) had an important clinical foundation, involving the observation of new phenomena and the formulation of new concepts. The second (between 1950 and 1960) included the introduction of more far-reaching concepts, such as the functional cortical gradient, and allometry laws based on a change of scale. Today, various authors believe that the concept of the gradient is crucial for understanding how the brain is organised.PMID:38502168 | DOI:10.33588/rn.7807.2024050 (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: A Garc ía-Molina I Gonzalo-Fonrodona Source Type: research

The p-value of the test is not a 'mathematical index', it is simply a relative frequency
Rev Neurol. 2024 Apr 1;78(7):209-211. doi: 10.33588/rn.7807.2023164.ABSTRACTLeading scientific journals in fields such as medicine, biology and sociology repeatedly publish articles and editorials claiming that a large percentage of doctors do not understand the basics of statistical analysis, which increases the risk of errors in interpreting data, makes them more vulnerable to misinformation and reduces the effectiveness of research. This problem extends throughout their careers and is largely due to the poor training they receive in statistics - a problem that is common in developed countries. As stated by H. Halle and ...
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: C Carazo-D íaz L Prieto-Valiente Source Type: research

RYR1 myopathies in childhood: phenotype-genotype correlation and incidence
CONCLUSIONS: RYR1-RM in our series exhibited phenotypic and involvement variability, with an incidence in our area of around 1 in 10,000 live births. Most cases were male, with dominant missense variants. We contribute five previously undescribed genetic variants.PMID:38502166 | DOI:10.33588/rn.7807.2023348 (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: N Del Arco-Guzm án S Lobato-L ópez R Calvo-Medina R Vera-Medialdea C Ruiz-P érez J M Ramos-Fern ández Source Type: research

Core data set for real world data in multiple sclerosis: customization for latin america from a global task force recommendation
CONCLUSION: The core data set seeks to harmonize the variables collected by registries and cohorts in MS in Latin America in order to facilitate said collection and allow collaboration between sources. Its implementation will facilitate real life data collection and collaboration in the region.PMID:38502167 | DOI:10.33588/rn.7807.2023326 (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: J I Rojas F Gracia T Parciak R Alonso J Becker I Trevi ño-Frenk M Alonso-Serena D Giunta P Abad E Carnero-Contentti A Carr á E P Correa-D íaz J Correale E Cristiano J Flores M Fruns L Galleguillos O Garcea F Hamuy M Lana-Peixoto C Navas R Pappais-Alvar Source Type: research

Chronology of Justo Gonzalo's research on brain dynamics
CONCLUSIONS: The theory of brain dynamics was established in two stages. The first (between 1938 and 1950) had an important clinical foundation, involving the observation of new phenomena and the formulation of new concepts. The second (between 1950 and 1960) included the introduction of more far-reaching concepts, such as the functional cortical gradient, and allometry laws based on a change of scale. Today, various authors believe that the concept of the gradient is crucial for understanding how the brain is organised.PMID:38502168 | DOI:10.33588/rn.7807.2024050 (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: A Garc ía-Molina I Gonzalo-Fonrodona Source Type: research

The p-value of the test is not a 'mathematical index', it is simply a relative frequency
Rev Neurol. 2024 Apr 1;78(7):209-211. doi: 10.33588/rn.7807.2023164.ABSTRACTLeading scientific journals in fields such as medicine, biology and sociology repeatedly publish articles and editorials claiming that a large percentage of doctors do not understand the basics of statistical analysis, which increases the risk of errors in interpreting data, makes them more vulnerable to misinformation and reduces the effectiveness of research. This problem extends throughout their careers and is largely due to the poor training they receive in statistics - a problem that is common in developed countries. As stated by H. Halle and ...
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: C Carazo-D íaz L Prieto-Valiente Source Type: research

RYR1 myopathies in childhood: phenotype-genotype correlation and incidence
CONCLUSIONS: RYR1-RM in our series exhibited phenotypic and involvement variability, with an incidence in our area of around 1 in 10,000 live births. Most cases were male, with dominant missense variants. We contribute five previously undescribed genetic variants.PMID:38502166 | DOI:10.33588/rn.7807.2023348 (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: N Del Arco-Guzm án S Lobato-L ópez R Calvo-Medina R Vera-Medialdea C Ruiz-P érez J M Ramos-Fern ández Source Type: research

Core data set for real world data in multiple sclerosis: customization for latin america from a global task force recommendation
CONCLUSION: The core data set seeks to harmonize the variables collected by registries and cohorts in MS in Latin America in order to facilitate said collection and allow collaboration between sources. Its implementation will facilitate real life data collection and collaboration in the region.PMID:38502167 | DOI:10.33588/rn.7807.2023326 (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: J I Rojas F Gracia T Parciak R Alonso J Becker I Trevi ño-Frenk M Alonso-Serena D Giunta P Abad E Carnero-Contentti A Carr á E P Correa-D íaz J Correale E Cristiano J Flores M Fruns L Galleguillos O Garcea F Hamuy M Lana-Peixoto C Navas R Pappais-Alvar Source Type: research

Chronology of Justo Gonzalo's research on brain dynamics
CONCLUSIONS: The theory of brain dynamics was established in two stages. The first (between 1938 and 1950) had an important clinical foundation, involving the observation of new phenomena and the formulation of new concepts. The second (between 1950 and 1960) included the introduction of more far-reaching concepts, such as the functional cortical gradient, and allometry laws based on a change of scale. Today, various authors believe that the concept of the gradient is crucial for understanding how the brain is organised.PMID:38502168 | DOI:10.33588/rn.7807.2024050 (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: A Garc ía-Molina I Gonzalo-Fonrodona Source Type: research

The p-value of the test is not a 'mathematical index', it is simply a relative frequency
Rev Neurol. 2024 Apr 1;78(7):209-211. doi: 10.33588/rn.7807.2023164.ABSTRACTLeading scientific journals in fields such as medicine, biology and sociology repeatedly publish articles and editorials claiming that a large percentage of doctors do not understand the basics of statistical analysis, which increases the risk of errors in interpreting data, makes them more vulnerable to misinformation and reduces the effectiveness of research. This problem extends throughout their careers and is largely due to the poor training they receive in statistics - a problem that is common in developed countries. As stated by H. Halle and ...
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: C Carazo-D íaz L Prieto-Valiente Source Type: research

RYR1 myopathies in childhood: phenotype-genotype correlation and incidence
CONCLUSIONS: RYR1-RM in our series exhibited phenotypic and involvement variability, with an incidence in our area of around 1 in 10,000 live births. Most cases were male, with dominant missense variants. We contribute five previously undescribed genetic variants.PMID:38502166 | DOI:10.33588/rn.7807.2023348 (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 19, 2024 Category: Neurology Authors: N Del Arco-Guzm án S Lobato-L ópez R Calvo-Medina R Vera-Medialdea C Ruiz-P érez J M Ramos-Fern ández Source Type: research