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Condition: Patent Foramen Ovale

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Total 1415 results found since Jan 2013.

Percutaneous Patent Foramen Ovale Closure After Stroke
Korean Circ J. 2022 Nov;52(11):801-807. doi: 10.4070/kcj.2022.0258.ABSTRACTPercutaneous patent foramen ovale (PFO) closure in patients with a prior PFO-associated stroke showed a risk reduction of the stroke recurrence compared to the medical therapy alone in recent several studies. Nevertheless, optimal patient selection for PFO closure has not been clarified. In this paper, we discuss the characteristics of PFO-associated strokes and discuss the recently published evidence and patient selection for PFO closure in patients with ischemic stroke. The lesions characteristics of PFO-associated stroke are associated with multi...
Source: Korean Circulation Journal - November 8, 2022 Category: Cardiology Authors: Oh-Hyun Lee Jung-Sun Kim Source Type: research

Differences in clinical and biological factors between patients with PFO-related stroke and patients with PFO and no cerebral vascular events
We present a study concerning clinical, demographic, and laboratory factors associated with stroke and transient ischemic attack in patients with patent foramen ovale (PFO), as well as comparing PFO-patients with and without cerebrovascular ischemic events (CVEs).Patients and methodsConsecutive patients with PFO-associated CVEs were included in the study; control group was selected from patients with a PFO and no history of stroke. All participants underwent peripheral routine blood analyses, as well as, on treating physician's recommendations, screening for thrombophilia.ResultsNinety-five patients with CVEs and 41 contro...
Source: Frontiers in Neurology - March 14, 2023 Category: Neurology Source Type: research

PFO closure vs. medical therapy in cryptogenic stroke or transient ischemic attack: A systematic review and meta-analysis
Conclusions: This meta-analysis does not support PFO closure for secondary prevention with unselected devices in cryptogenic stroke/TIA. In subgroup analysis, selected closure devices may be superior to medical therapy without increasing the risk of new-onset AF, however. This observation should be confirmed in further trials using inclusion criteria for patients with high likelihood of PFO-related stroke recurrence.
Source: International Journal of Cardiology - September 16, 2013 Category: Cardiology Authors: G. Ntaios, V. Papavasileiou, K. Makaritsis, P. Michel Tags: Reviews Source Type: research

Amplatzer PFO Occluder Device may Prevent Recurrent Stroke in Patients with Patent Foramen Ovale and Cryptogenic Stroke: A Meta-Analysis of Randomised Trials
Conclusion: The closure of PFO with Amplatzer PFO occluder device was associated with significant reduction in recurrent strokes in patients with cryptogenic stroke and patent foramen ovale. The better outcome in prevention of secondary stroke in patients with cryptogenic stroke and PFO may be associated with type of closure device used.
Source: Heart, Lung and Circulation - February 4, 2014 Category: Cardiology Authors: Anil Pandit, Madan Raj Aryal, Aashrayata Aryal Pandit, Leena Jalota, Sudheer Kantharajpur, Fayaz A. Hakim, Howard R. Lee Tags: Reviews Source Type: research

Percutaneous Closure versus Medical Therapy Alone for Cryptogenic Stroke Patients with a Patent Foramen Ovale: Meta-Analysis of Randomized Controlled Trials.
Abstract Of cryptogenic stroke patients younger than 55 years of age, up to 61% have had a patent foramen ovale (PFO). Observational studies have revealed reductions in recurrent neurologic events through PFO closure versus medical therapy, and randomized controlled trials have shown nonsignificant trends toward benefit. We systematically searched for randomized controlled trials of percutaneous PFO closure with medical therapy versus medical therapy alone in patients with cryptogenic stroke and performed a meta-analysis of treatment outcomes. The primary endpoint was combined death, stroke, and transient ischemic...
Source: Texas Heart Institute Journal - August 1, 2014 Category: Cardiology Authors: Pickett CA, Villines TC, Ferguson MA, Hulten EA Tags: Tex Heart Inst J Source Type: research

Usefulness of transesophageal echocardiography to optimize treatment after ischemic stroke.
CONCLUSIONS: In the setting of ischemic stroke, TEE provides important additional informations, but modifies therapeutic strategy in less than 10% of cases. Multivessel territory stroke, and left atrial dilatation were predictive of DTEE. PMID: 25245599 [PubMed - as supplied by publisher]
Source: Annales de Cardiologie et d'Angeiologie - September 4, 2014 Category: Cardiology Authors: Charbonnel C, Fanon L, Georges JL, Colonna G, Stefas L, Isorni C, Convers-Domart R, Galuscan G, Baron N, Pico F, Livarek B Tags: Ann Cardiol Angeiol (Paris) Source Type: research

PFO Closure for Cryptogenic Stroke
Abstract A patent foramen ovale (PFO) is a common finding in the general population and has been theorized to be a mechanism for ischemic stroke primarily due to a deep venous thrombus embolizing through the shunt into the arterial circulation. There has been much debate regarding the association between PFO and stroke, especially in the case of a cryptogenic stroke (i.e., stroke of unknown etiology) in a younger patient without other risk factors. Traditionally, when a PFO is detected, antithrombotic therapy to mitigate risk of a future ischemic event has been the mainstay of treatment. More recently, both surgi...
Source: Current Atherosclerosis Reports - June 17, 2015 Category: Cardiology Source Type: research

E-051 acute ischemic stroke due to tumorigenic embolism treated with mechanical thrombectomy
ConclusionIn acute stroke secondary to malignant tumorigenic embolism, mechanical thrombectomy might be a safe and effective treatment option.DisclosuresB. Bell: None. A. Saad: None. K. Layton: None. S. Shamim: None. G. Snipes: None. K. Hesselrode: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Bell, B., Saad, A., Layton, K., Shamim, S., Snipes, G., Hesselrode, K. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

Anticoagulant vs. antiplatelet therapy in patients with cryptogenic stroke and patent foramen ovale: an individual participant data meta-analysis
Conclusion We did not find a statistically significant difference comparing OAC with APT; our results justify randomized trials comparing different antithrombotic approaches in these patients.
Source: European Heart Journal - September 14, 2015 Category: Cardiology Authors: Kent, D. M., Dahabreh, I. J., Ruthazer, R., Furlan, A. J., Weimar, C., Serena, J., Meier, B., Mattle, H. P., Di Angelantonio, E., Paciaroni, M., Schuchlenz, H., Homma, S., Lutz, J. S., Thaler, D. E. Tags: Thrombosis and antithrombotic therapy Source Type: research

Isolated asymptomatic pulmonary arteriovenous malformation presenting with ischaemic stroke
Publication date: Available online 17 February 2016 Source:Journal of Clinical Neuroscience Author(s): Kelly L. Bertram, Anoop Madan, Judith Frayne Young onset stroke is uncommon, and may be due to conditions other than traditional vascular risk factors. A 42-year-old woman with an ischaemic stroke was found to have left atrial bubble study positivity on transthoracic echocardiogram (TTE) suggestive of patent foramen ovale, however she also had low peripheral oxygen saturation. Investigation revealed an isolated pulmonary arteriovenous malformation (PAVM), visible on admission chest radiograph. This can cause embolic ...
Source: Journal of Clinical Neuroscience - February 18, 2016 Category: Neuroscience Source Type: research

Comparison of Outcomes after Device Closure and Medication Alone in Patients with Patent Foramen Ovale and Cryptogenic Stroke in Korean Population.
CONCLUSION: Compared to medical therapy, device closure of PFO in patients with cryptogenic stroke did not show difference in reduction of recurrent embolic events in the real world's setting. However, considering high risk of echocardiographic findings in the closure group, further investigation of the role of PFO closure in the Asian population is needed. PMID: 26996560 [PubMed - in process]
Source: Yonsei Medical Journal - March 23, 2016 Category: Universities & Medical Training Authors: Moon J, Kang WC, Kim S, Oh PC, Park YM, Chung WJ, Choi DY, Lee JY, Lee YB, Hwang HY, Ahn T Tags: Yonsei Med J Source Type: research

Endocardial Device Leads in Patients with Patent Foramen Ovale: Echocardiographic Correlates of Stroke/TIA and Mortality
ConclusionsIn patients with CIED and PFO, structural and hemodynamic echocardiographic markers did not predict future stroke/TIA. However, a significantly higher TR or RVSP was associated with higher mortality.This article is protected by copyright. All rights reserved
Source: Pacing and Clinical Electrophysiology : PACE - October 31, 2016 Category: Cardiology Authors: SHIVA P. PONAMGI, VAIBHAV R. VAIDYA, CHRISTOPHER V. DESIMONE, AMIT NOHERIA, DAVID O. HODGE, JOSHUA P. SLUSSER, NASER M. AMMASH, CHARLES J. BRUCE, ALEJANDRO A. RABINSTEIN, PAUL A. FRIEDMAN, SAMUEL J. ASIRVATHAM Tags: BASIC SCIENCE Source Type: research

Relationship between mean platelet volume and ischemic stroke in patients with patent foramen ovale.
CONCLUSION: MPV is higher in symptomatic than in asymptomatic PFO patients. This finding may be a subsidiary risk factor to identify patients with PFO and high risk of cardioembolic stroke. PMID: 28106015 [PubMed - in process]
Source: Turk Kardiyoloji Dernegi arsivi - December 31, 2016 Category: Cardiology Authors: Bayar N, Küçükseymen S, Erkal Z, Güven R, Köklü E, Üreyen ÇM, Arslan Ş Tags: Turk Kardiyol Dern Ars Source Type: research

Migraine and Stroke: What ’s the Link? What to Do?
AbstractMigraine and stroke are common, disabling neurologic disorders, with a high socioeconomic burden. A link between them has been proposed years ago, and various theories have been proposed to explain this bidirectional relation. However, the precise causes remain unclear. We briefly summarize existing hypotheses of this correlation seeking for recommendations for stroke prevention in migraineurs, if any exist. Among the strongest suggested theories of migraine –stroke association are cortical spreading depression, endovascular dysfunction, vasoconstriction, neurogenic inflammation, hypercoagulability, increased pre...
Source: Current Neurology and Neuroscience Reports - March 9, 2017 Category: Neuroscience Source Type: research

Advanced imaging in acute ischemic stroke.
Abstract The evaluation and management of acute ischemic stroke has primarily relied on the use of conventional CT and MRI techniques as well as lumen imaging sequences such as CT angiography (CTA) and MR angiography (MRA). Several newer or less-established imaging modalities, including vessel wall MRI, transcranial Doppler ultrasonography, and 4D CTA and MRA, are being developed to complement conventional CT and MRI techniques. Vessel wall MRI provides high-resolution analysis of both extracranial and intracranial vasculature to help identify previously occult lesions or characteristics of lesions that may porten...
Source: Neurosurgical Focus - April 1, 2017 Category: Neurosurgery Authors: Kilburg C, Scott McNally J, de Havenon A, Taussky P, Kalani MY, Park MS Tags: Neurosurg Focus Source Type: research