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Condition: Patent Foramen Ovale

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Total 1415 results found since Jan 2013.

Impact of transesophageal echocardiography on clinical management of patients over age 50 with cryptogenic stroke and normal transthoracic echocardiogram
CONCLUSIONIn our study population, when performed subsequent to a normal TTE in patients aged >50 years with cryptogenic stroke, TEE demonstrated a high diagnostic value, but had minimal incremental effect on patient management. Journal of Hospital Medicine 2015. © 2015 Society of Hospital Medicine
Source: Journal of Hospital Medicine - September 21, 2015 Category: Hospital Management Authors: Brian Marino, Abhishek Jaiswal, Seth Goldbarg, Gary L. Bernardini, Todd Kerwin Tags: Original Research Source Type: research

Analysis of Inpatient Thrombophilia Testing for Adults with an Ischemic Stroke or Transient Ischemic Attack and its Impact on Clinical Management (P1.123)
Conclusions: Inpatient thrombophilia testing did not affect management in the vast majority of patients with an ischemic stroke or TIA despite a positive test result. Therefore, by avoiding inpatient testing, healthcare costs may be reduced without affecting patient care.Disclosure: Dr. Gavva has nothing to disclose. Dr. Alberts has received personal compensation for activities with AGA medical, AstraZeneca, Bayer, Pfizer, Bistol-Myers-Squibb, Boehringer Ingelheim, diaDexus, Genentech, KOS, Medicine Company, PDL biopharma, Pfizer, Photothera, Sanofi. Dr. Johnson has nothing to disclose. Dr. Sarode has received personal com...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Gavva, C., Alberts, M., Johnson, M., Sarode, R. Tags: Cerebrovascular Disease: Epidemiology Source Type: research

Unresolved or Contradictory Issues About Management of Patients With Patent Foramen Ovale and Previous Cryptogenic Stroke: Additional Randomized Controlled Trials Are Eagerly Awaited.
Abstract Stating a well-codified and widely accepted therapeutic conduct for patients with patent foramen ovale (PFO) and previous cryptogenic stroke is made difficult and somewhat controversial by several issues remained unresolved so far. In this short review, some aspects of the possible role played by the PFO in the pathogenesis of cryptogenic stroke are succinctly analyzed. First, some aspects of cardiovascular anatomy of the human fetus and the adult are outlined. Subsequently, the three randomized controlled trials (RCTs) that have been accomplished so far to compare the implant of a transeptal occluding de...
Source: Clin Med Res - April 19, 2016 Category: Research Authors: De Vecchis R, Baldi C Tags: J Clin Med Res Source Type: research

Cryptogenic Stroke: Making the Management Less Cryptic
Cryptogenic stroke (CS) accounts for 20% to 40% of ischemic strokes. CS is defined as a cortical infarct suggestive of an embolic stroke with no identifiable cardiac etiology, large vessel occlusive disease, or small vessel lacunar stroke. The likely etiologies for CS are patent foramen ovale (PFO) and paroxysmal atrial fibrillation, which can be detected by transesophageal echocardiography and long-term cardiac rhythm monitoring. In a busy academic hospital, the stroke service is frequently asked to provide a rational approach to patients with such a presentation. The 2011 American Heart Association/American Stroke Associ...
Source: Cardiology in Review - June 4, 2016 Category: Cardiology Tags: Review Articles Source Type: research

Patent Foramen Ovale and Stroke.
Abstract A patent foramen ovale (PFO) is common and found in nearly 25% of healthy individuals. The majority of patients with PFO remain asymptomatic and they are not at increased risk for developing a stroke. The presence of PFO, however, has been found to be higher in patients with cryptogenic stroke, suggesting there may be a subset of patients with PFO who are indeed at risk for stroke. Paradoxical embolization of venous thrombi through the PFO, which then enter the arterial circulation, is hypothesized to account for this relationship. Although aerated-saline transesophageal echocardiography is the gold stand...
Source: Circulation Journal - June 21, 2016 Category: Cardiology Authors: Sun YP, Homma S Tags: Circ J Source Type: research

Patent foramen ovale and cryptogenic stroke: from studies to clinical practice
ConclusionAfter many years of interest on PFO and many concluded studies, there are still no definitive data. However, we are on good track for an appropriate management of PFO patients and cryptogenic stroke.
Source: International Journal of Clinical Practice - July 6, 2016 Category: Internal Medicine Authors: K. Savino, M. Maiello, F. Pelliccia, G. Ambrosio, P. Palmiero Tags: Systematic Review Source Type: research

Cryptogenic stroke and patent foramen ovale: The role of Valsalva maneuver and prolonged immobility (P3.079)
Conclusions:Our study provides an estimated prevalence of Valsalva maneuver and prolonged immobility in patients with CS and PFO. The analysis suggests a possible association between high RoPE score and prolonged immobility, in patients with Valsalva at the time of symptom onset. Further investigations with larger sample sizes are required to reach more precise estimates for the associations examined.Disclosure: Dr. Daneshmand has nothing to disclose. Dr. Koulouridis has nothing to disclose. Dr. Thaler has received personal compensation for activities with St. Jude Medical WL and Gore Associates as a consultant.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Daneshmand, A., Koulouridis, I., Thaler, D. Tags: Cerebrovascular Disease and Interventional Neurology ePoster Session Source Type: research

Long-term Risk of Complications after Percutaneous Transcatheter Closure of Patent Foramen Ovale (S51.003)
Conclusions:Approximately 1 in 6 patients who undergo percutaneous transcatheter closure of PFO after stroke or transient ischemic attack experience a serious complication or death within 5 years.Study Supported by:Dr. Gialdini is supported by the Feil Family Foundation.Dr. Navi is supported by NIH grant K23NS091395 and the Florence Gould Endowment for Discovery in Stroke.Dr. Iadecola is supported by NIH grants R37NS089323-02, R01NS034179-21, R01NS037853-19, and R01 NS073666-04.Dr. Kamel is supported by NIH grants K23NS082367 and R01NS097443 as well as the Michael Goldberg Research Fund.Disclosure: Dr. Merkler has nothing ...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Merkler, A., Gialdini, G., Yaghi, S., Okin, P., Iadecola, C., Navi, B., Kamel, H. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke Prevention and Translation Source Type: research

Patent foramen ovale and cryptogenic stroke: contemporary evidence and treatment.
Authors: Coughlan JJ, Daly A, Arnous S, Kiernan TJ Abstract INTRODUCTION: Patent foramen ovale (PFO) is a common anatomical variant in the adult circulation. It is a channel allowing communication between the left and right atria and is a remnant of the foetal circulation. In approximately 25% of the population, this channel persists into adulthood. PFO has been proposed as a potential pathophysiological mechanism for cryptogenic stroke. Areas covered: This review will examine the contemporary evidence for both the association between cryptogenic stroke and PFO and the management of this condition. The authors hope...
Source: Expert Review of Cardiovascular Therapy - December 20, 2017 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Transcatheter closure of patent foramen ovale following cryptogenic stroke: An updated meta-analysis of randomized controlled trials
Conclusions Transcatheter closure is associated with a significant reduction in the risk of stroke compared to medical management at the expense of an increased risk of atrial arrhythmias.
Source: American Heart Journal - February 1, 2018 Category: Cardiology Source Type: research

Patent foramen ovale closure versus medical therapy after cryptogenic stroke: An updated meta-analysis of all randomized clinical trials.
CONCLUSION: Patent foramen ovale closure in adults with recent cryptogenic stroke was associated with a lower rate of recurrent strokes in comparison with medical therapy alone. PMID: 29512097 [PubMed - as supplied by publisher]
Source: Cardiology Journal - March 7, 2018 Category: Cardiology Authors: Kheiri B, Abdalla A, Osman M, Ahmed S, Hassan M, Bachuwa G Tags: Cardiol J Source Type: research

Transcatheter Closure of Patent Foramen Ovale versus Medical Therapy after Cryptogenic Stroke: A Meta-Analysis of Randomized Controlled Trials
Conclusion: Pooled data from 5 large RCTs showed that PFO closure in patients with cryptogenic stroke is safe and effective intervention for prevention of stroke recurrence compared with medical therapy.Cerebrovasc Dis 2018;45:162 –169
Source: Cerebrovascular Diseases - March 29, 2018 Category: Neurology Source Type: research

Closure of Patent Foramen Ovale versus Medical Therapy after Cryptogenic Stroke: Meta-Analysis of Five Randomized Controlled Trials with 3440 Patients
Conclusion: This meta-analysis found that stroke rates are lower with percutaneously implanted device closure than with medical therapy alone, being these rates modulated by the rates of effective closure.
Source: Revista Brasileira de Cirurgia Cardiovascular - March 29, 2018 Category: Cardiovascular & Thoracic Surgery Source Type: research

Patent foramen ovale closure or medical therapy for secondary prevention of cryptogenic stroke: An update meta-analysis of randomized controlled trials
Conclusion: PFO closure, as compared with medical therapy, was associated with decreased risk of recurrent stroke and increased risk of atrial fibrillation in cryptogenic stroke patients with PFO.
Source: Medicine - August 1, 2018 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Study of transesophageal echocardiography in young patients (<40 years) with acute arterial ischemic stroke: A pilot study
ConclusionCardiac abnormalities on TEE and holter were detected in 42.5% of the young patients with idiopathic arterial stroke. TEE abnormality was noted in 33% (13/40), whereas AF on holter was seen in 14.8% (4/27) with normal TEE. Thus, probable cardioembolic stroke was responsible for acute ischemic stroke in 42.5% (17/40) of young patients in the absence of valvular heart disease, prosthetic valves, and persistent/permanent AF.
Source: Medical Journal Armed Forces India - October 16, 2018 Category: General Medicine Source Type: research