Log in to search using one of your social media accounts:

 

Topographical Distribution of Perioperative Cerebral Infarction Associated with Transcatheter Aortic Valve Implantation
Conclusions The distribution of lesions that we detected suggests that cortical grey matter, the posterior circulation, and the right hemisphere are all particularly vulnerable to perioperative cerebrovascular injury. This finding has implications for the use of intraoperative cerebral embolic protection devices, particularly those that leave the left subclavian and, therefore, left vertebral artery unprotected. Graphical abstract (Source: American Heart Journal)
Source: American Heart Journal - December 9, 2017 Category: Cardiology Source Type: research

The Optimal Anti-Coagulation for Enhanced Risk Patients Post-Catheter Ablation for Atrial Fibrillation (OCEAN) trial
Discussion The OCEAN trial is a multicenter randomized controlled trial evaluating two antithrombotic treatment strategies for patients with risk factors for stroke after apparently successful AF ablation. We hypothesize that rivaroxaban will reduce the occurrence of clinically overt stroke, systemic embolism, and covert stroke when compared to ASA alone. (Source: American Heart Journal)
Source: American Heart Journal - December 9, 2017 Category: Cardiology Source Type: research

Improving Patient Risk Communication: Translating Cardiovascular Risk into Standardized Risk Percentiles
Conclusion Cardiovascular risk varies substantially by age, sex, and race. These data allow for 10-year absolute risks of ASCVD to be translated into a standardized cardiovascular risk percentile, providing patients with information that is easy to understanding regarding how their personal risk of cardiovascular disease compares with their age-, sex-, and race-matched peers. (Source: American Heart Journal)
Source: American Heart Journal - December 8, 2017 Category: Cardiology Source Type: research

A “Shocking” New Code Status
Publication date: Available online 7 December 2017 Source:American Heart Journal Author(s): Anant Mandawat, Aditya Mandawat, Gregory Curfman, L. Kristin Newby (Source: American Heart Journal)
Source: American Heart Journal - December 8, 2017 Category: Cardiology Source Type: research

A Genotype-Directed Comparative Effectiveness Trial of Bucindolol and Metoprolol Succinate for Prevention of Symptomatic Atrial Fibrillation/Atrial Flutter in Patients with Heart Failure: Rationale and Design of the GENETIC-AF Trial
Conclusions GENETIC-AF is the first randomized trial of pharmacogenetic guided rhythm control, and will test the safety and efficacy of bucindolol compared with metoprolol succinate for the prevention of recurrent symptomatic AF/AFL in patients with HFrEF and an ADRB1 Arg389Arg genotype. (ClinicalTrials.gov NCT01970501). (Source: American Heart Journal)
Source: American Heart Journal - December 7, 2017 Category: Cardiology Source Type: research

Rationale and design of the comparison between a P2Y12 inhibitor monotherapy versus dual antiplatelet therapy in patients undergoing implantation of coronary drug-eluting stents (SMART-CHOICE): A prospective multicenter randomized trial
Conclusions The SMART-CHOICE trial aims to examine the non-inferiority of monotherapy with one of any available oral P2Y12 inhibitors versus conventional DAPT of an identical P2Y12 inhibitor plus aspirin in a broad spectrum of patients receiving representative current-generation DES. (Source: American Heart Journal)
Source: American Heart Journal - December 7, 2017 Category: Cardiology Source Type: research

Efficacy and Safety of Dual Antiplatelet Therapy after Coronary Stenting in Patients with Chronic Kidney Disease
Conclusions The rates of POCO and coronary thrombotic events were significantly higher in patients with CKD compared with those without CKD, which was not affected by short- or long-term DAPT. Higher bleeding incidence by long-term DAPT was only observed in non-CKD patients but not in CKD patients. Further large scales studies are warranted to confirm our findings. (Source: American Heart Journal)
Source: American Heart Journal - December 7, 2017 Category: Cardiology Source Type: research

The Effect of High-Dose Atorvastatin on Neural Activity and Cognitive Function
Conclusion Six months of high dose atorvastatin therapy is not associated with measurable changes in neuropsychological test scores, but did evoke transient differences in brain activation patterns. Larger, longer-term clinical trials are necessary to confirm these findings and evaluate their clinical implications. (Source: American Heart Journal)
Source: American Heart Journal - December 7, 2017 Category: Cardiology Source Type: research

Cognition and brain changes associated with high-dose atorvastatin: A BOLD proposition?
Publication date: Available online 6 December 2017 Source:American Heart Journal Author(s): Jeffrey N. Browndyke, Mitchell T. Heflin (Source: American Heart Journal)
Source: American Heart Journal - December 7, 2017 Category: Cardiology Source Type: research

Association of Lipoprotein-associated Phospholipase A2 and risk of incident atrial fibrillation: Findings from three cohorts
Conclusions While higher Lp-PLA2 mass and activity were associated with development of AF in ARIC and MESA, this relationship was not observed in CHS, a cohort of older individuals. (Source: American Heart Journal)
Source: American Heart Journal - December 6, 2017 Category: Cardiology Source Type: research

Percutaneous Coronary Intervention of Lesions With In-Stent Restenosis: A Report From the ADAPT-DES Study
Conclusions ISR PCI is associated with a considerably higher risk of 2-year adverse ischemic events, with HPR conferring similar risk in ISR and non-ISR PCI. More effective therapeutic strategies for managing ISR lesions are necessary. (Source: American Heart Journal)
Source: American Heart Journal - December 6, 2017 Category: Cardiology Source Type: research

Design of DISCO - Direct or Subacute Coronary Angiography in Out-of-Hospital Cardiac Arrest Study
Conclusion This randomized clinical study will evaluate the effect of immediate coronary angiography after OHCA on 30-day survival in patients without ST elevation on their first recorded ECG. (Source: American Heart Journal)
Source: American Heart Journal - December 6, 2017 Category: Cardiology Source Type: research

Left Ventricular Ejection Fraction Reassessment Post-Myocardial Infarction: Current Clinical Practice and Determinants of Adverse Remodeling
Conclusions Current practice of LVEF reassessment during the convalescent months post-MI is suboptimal, despite a sizeable proportion of patients that undergo adverse LV remodeling. Targeting processes affecting low rates of LVEF reassessment may reduce missed care opportunities and ensure that patients consistently receive appropriate evidence-based and guideline-recommended care. (Source: American Heart Journal)
Source: American Heart Journal - December 6, 2017 Category: Cardiology Source Type: research

High-sensitivity cardiac troponin T, left-ventricular function and outcome in non-ST elevation acute coronary syndrome
Conclusions Hs-cTnT levels provide incremental prognostic value independent of the LVEF in patients with NSTE-ACS. Hs-cTnT is particularly predictive for MACE in patients with severely depressed LVEF but also in those with a normal LVEF. Accordingly, a normal LVEF should not be used as an argument not to target patients to thorough work-up. (Source: American Heart Journal)
Source: American Heart Journal - December 6, 2017 Category: Cardiology Source Type: research

Health promotion: A step beyond prevention in cardiology
Publication date: Available online 2 December 2017 Source:American Heart Journal Author(s): Marcio Sommer Bittencourt (Source: American Heart Journal)
Source: American Heart Journal - December 3, 2017 Category: Cardiology Source Type: research

Comparison of Drug-Eluting Stents and Drug-Coated Balloon for The Treatment of Drug-Eluting Coronary Stent Restenosis: A Randomized RESTORE trial
Conclusions Treatment of DES ISR using DEB or second-generation DES did not differ in terms of late loss at 9-month angiographic follow-up, while DES showed better angiographic results regarding minimal MLD and percent diameter stenosis. Both treatment strategies were safe and effective up to 1year after the procedure. (Source: American Heart Journal)
Source: American Heart Journal - December 1, 2017 Category: Cardiology Source Type: research

Fine particulate matter and incident coronary heart disease in the REGARDS cohort
Publication date: Available online 22 November 2017 Source:American Heart Journal Author(s): Matthew Shane Loop, Leslie A. McClure, Emily B. Levitan, Mohammad Z. Al-Hamdan, William L. Crosson, Monika M. Safford Chronic exposure to fine particulate matter (PM2.5) is accepted as a causal risk factor for coronary heart disease (CHD). However, most of the evidence for this hypothesis is based upon cohort studies in whites, comprised of either only males or females who live in urban areas. It is possible that many estimates of the effect of chronic exposure to PM2.5 on risk for CHD do not generalize to more diverse samples. Th...
Source: American Heart Journal - December 1, 2017 Category: Cardiology Source Type: research

The influence of febuxostat on coronary artery endothelial dysfunction in patients with coronary artery disease: A phase 4 randomized, placebo-controlled, double-blind, crossover trial
Conclusion In summary, although XO inhibition with febuxostat was well tolerated and lowered serum urate, it did not improve the primary endpoint of the study, CEF measured using MRI after six weeks of treatment. In conclusion, these findings suggest that short-term inhibition of XO does not significantly improve impaired CEF in patients with stable CAD. (Source: American Heart Journal)
Source: American Heart Journal - December 1, 2017 Category: Cardiology Source Type: research

Design of a bilevel clinical trial targeting adherence in heart failure patients and their providers: The Congestive Heart Failure Adherence Redesign Trial (CHART)
Conclusion CHART will determine the value of intervening on low adherence simultaneously in physicians and their socioeconomically disadvantaged patients in reducing all-cause hospitalization days. (Source: American Heart Journal)
Source: American Heart Journal - December 1, 2017 Category: Cardiology Source Type: research

Toward personalized risk assessment in patients with chronic heart failure: Detailed temporal patterns of NT-proBNP, troponin T, and CRP in the Bio-SHiFT study
Publication date: February 2018 Source:American Heart Journal, Volume 196 Author(s): Nick van Boven, Linda C. Battes, K. Martijn Akkerhuis, Dimitris Rizopoulos, Kadir Caliskan, Sharda S. Anroedh, Wisam Yassi, Olivier C. Manintveld, Jan-Hein Cornel, Alina A. Constantinescu, Eric Boersma, Victor A. Umans, Isabella Kardys (Source: American Heart Journal)
Source: American Heart Journal - December 1, 2017 Category: Cardiology Source Type: research

Effect of adding GLP-1RA on mortality, cardiovascular events, and metabolic outcomes among insulin-treated patients with type 2 diabetes: A large retrospective UK cohort study
Conclusion Based on a large UK cohort in routine clinical practice, adding a GLP-1RA to insulin therapy is associated with a reduction in risk of composite CV events and all-cause mortality but a nonsignificant higher risk of hospitalization for heart failure in overweight patients with T2D. (Source: American Heart Journal)
Source: American Heart Journal - December 1, 2017 Category: Cardiology Source Type: research

Access to routine care and risks for 30-day readmission in patients with cardiovascular disease
Conclusions Cardiovascular patients who reported difficulty in accessing routine care had substantial risks of readmission within 30 days after discharge. These findings have important implications for identifying high-risk patients and developing interventions to improve access to routine medical care. (Source: American Heart Journal)
Source: American Heart Journal - December 1, 2017 Category: Cardiology Source Type: research

Thrombus aspiration and prehospital ticagrelor administration in ST-elevation myocardial infarction: Findings from the ATLANTIC trial
Conclusions TA when left to physicians’ discretion was used in high-risk patients, was associated with bailout use of glycoprotein IIb/IIIa inhibitors and TIMI major bleeding, and had no impact on 30-day clinical outcomes. Conversely, pre-H ticagrelor treatment predicted lower 30-day rates of ST or new MI without interaction with TA. (Source: American Heart Journal)
Source: American Heart Journal - December 1, 2017 Category: Cardiology Source Type: research

Return to the workforce following infective endocarditis —A nationwide cohort study
Conclusions Seven of 10 patients who were part of the workforce prior to IE and alive at discharge were part of the workforce 1 year later. Younger age, higher socioeconomic status, and absence of major comorbidities were associated with return to the workforce. (Source: American Heart Journal)
Source: American Heart Journal - November 16, 2017 Category: Cardiology Source Type: research

Factors of health in the protection against death and cardiovascular disease among adults with subclinical atherosclerosis
Conclusions Adults with elevated CAC appear to have healthy lifestyle options to lower risk and delay onset of CVD, over and above standard preventive therapies. (Source: American Heart Journal)
Source: American Heart Journal - November 12, 2017 Category: Cardiology Source Type: research

Percutaneous Coronary Intervention and Antiplatelet Therapy in Patients with Atrial Fibrillation Receiving Apixaban or Warfarin: Insights from the ARISTOTLE Trial
Conclusions PCI occurred infrequently during follow-up. The majority of patients on study drug at the time of PCI remained on study drug in the peri-PCI period; 19% continued the study drug without interruption. Antiplatelet therapy use post-PCI was variable, though the majority of patients received DAPT. Additional data are needed to guide the use of antithrombotics in patients undergoing PCI. (Source: American Heart Journal)
Source: American Heart Journal - November 10, 2017 Category: Cardiology Source Type: research

Prediction of long-term net clinical outcomes using the TIMI-AF score: Comparison with CHA2DS2-VASc and HAS-BLED
Conclusions In VKA-experienced AF patients, the TIMI-AF score has limited usefulness predicting NCOs over a long-term period of follow-up. This novel score was not superior to CHA2DS2-VASc and HAS-BLED identifying ‘low risk’ AF patients. (Source: American Heart Journal)
Source: American Heart Journal - November 10, 2017 Category: Cardiology Source Type: research

Duration of Ischemia and Treatment Effects of Pre- Versus In-Hospital Ticagrelor in Patients with ST-Segment Elevation Myocardial Infarction: Insights from the ATLANTIC study
Conclusions The effect of pre-hospital ticagrelor to reduce stent thrombosis was most evident when given early within 3hours after symptom onset, with delay in ticagrelor administration after symptom onset associated with higher rate of stent thrombosis. These findings re-emphasize the need for early ticagrelor administration in primary PCI treated STEMI patients. (Source: American Heart Journal)
Source: American Heart Journal - November 9, 2017 Category: Cardiology Source Type: research

Changes in Lipoprotein(a) following Bariatric Surgery
Publication date: Available online 4 November 2017 Source:American Heart Journal Author(s): Bing-Xue Lin, Matthew C. Weiss, Manish Parikh, Jeffrey S. Berger, Edward A. Fisher, Sean P. Heffron (Source: American Heart Journal)
Source: American Heart Journal - November 9, 2017 Category: Cardiology Source Type: research

Rationale and design of the DEAR-OLD trial: randomized evaluation of routinely Deferred versus EARly invasive strategy in elderly patients of 75years or OLDer with non-ST-elevation myocardial infarction
Conclusions the DEAR-OLD trial is a prospective, nationwide, multi-center, non-inferiority designed, open-label randomized clinical trial evaluating efficacy and safety of routinely deferred invasive strategy compared with early invasive strategy in Chinese elderly patients with NSTEMI. (Source: American Heart Journal)
Source: American Heart Journal - November 9, 2017 Category: Cardiology Source Type: research

Representation of Black Patients in Randomized Clinical Trials of Heart Failure with Reduced Ejection Fraction
Conclusions Black patients are modestly represented among pivotal RCTs of individuals with HFrEF for both pharmacotherapies and ICDs. The current trend for decreasing black representation in trials of HF therapeutics is concerning and must improve to ensure the generalizability for this vulnerable population. (Source: American Heart Journal)
Source: American Heart Journal - November 9, 2017 Category: Cardiology Source Type: research

Non-Primary PCI at Hospitals without Cardiac Surgery On-Site: Consistent Outcomes for All?
Conclusions The non-inferiority of non-primary PCI at non-SoS hospitals was consistent across clinically relevant subgroups. Elective PCI at an SoS hospital conferred a TVR benefit which may be related to a lower rate of referral for diagnostic catheterization for reasons other than myocardial infarction. (Source: American Heart Journal)
Source: American Heart Journal - November 9, 2017 Category: Cardiology Source Type: research

Comparison of Fractional FLow Reserve And Intravascular ultrasound-guided Intervention Strategy for Clinical OUtcomes in Patients with InteRmediate Stenosis (FLAVOUR): Rationale and design of a randomized clinical trial
Conclusion The FLAVOUR trial will compare the safety and efficacy of FFR- and IVUS-guided PCI strategies in patients with intermediate coronary stenosis. This study will provide an insight on optimal evaluation and treatment strategy for patients with intermediate coronary stenosis. (Source: American Heart Journal)
Source: American Heart Journal - November 9, 2017 Category: Cardiology Source Type: research

Prognostic value of viral eradication for major adverse cardiovascular events in hepatitis C cirrhotic patients
Conclusion In patients with compensated HCV-related cirrhosis, Asian ethnic origin, arterial hypertension, smoking and low serum albumin are independent predictive factors of cardiovascular events, while a sustained virological response is associated with a decreased rate of cardiovascular events. (Source: American Heart Journal)
Source: American Heart Journal - November 9, 2017 Category: Cardiology Source Type: research

Efficacy and safety of potent platelet P2Y12 receptor inhibitors in elderly versus nonelderly patients with acute coronary syndrome: A systematic review and meta-analysis
Conclusions The effect of more potent P2Y12 inhibitors compared with clopidogrel on efficacy and safety end points is consistent in elderly and younger patients. These data imply that potent P2Y12 inhibitors should not be withheld from eligible patients solely because of advanced age. (Source: American Heart Journal)
Source: American Heart Journal - November 9, 2017 Category: Cardiology Source Type: research

Effect of high-dose oral multivitamins and minerals in participants not treated with statins in the randomized Trial to Assess Chelation Therapy (TACT)
Conclusion and relevance High-dose oral multivitamin and multimineral supplementation seem to decrease combined cardiac events in a stable, post-MI population not taking statin therapy at baseline. These unexpected findings are being retested in the ongoing TACT2. (Source: American Heart Journal)
Source: American Heart Journal - November 9, 2017 Category: Cardiology Source Type: research

Mineralocorticoid receptor antagonists in patients with acute myocardial infarction — A systematic review and meta-analysis of randomized trials
Conclusions Administration of MRA may reduce mortality after acute MI. However, this is largely based on post-MI patients with heart failure. Further data are needed in MI patients without heart failure. (Source: American Heart Journal)
Source: American Heart Journal - November 9, 2017 Category: Cardiology Source Type: research

Variation in practice patterns in device closure of atrial septal defects and patent ductus arteriosus: An analysis of data from the IMPACT ® Registry
Conclusion There is measurable variation in transcatheter closure of PDA and ASD. Further research is necessary to study whether this affects outcomes or resource utilization. (Source: American Heart Journal)
Source: American Heart Journal - November 3, 2017 Category: Cardiology Source Type: research

Comprehensive Electrocardiogram-to-Device Time for Primary Percutaneous Coronary Intervention in ST-segment Elevation Myocardial Infarction: A Report from the American Heart Association Mission: Lifeline ® Program
Conclusions Comprehensive ECG-to-device time provides an integrated hospital-related network-level assessment of reperfusion timing metrics for primary PCI, regardless of the location for STEMI identification; further validation will delineate how this metric can be used to facilitate STEMI care improvements. (Source: American Heart Journal)
Source: American Heart Journal - November 3, 2017 Category: Cardiology Source Type: research

Biomarkers in Stable Coronary Artery Disease
Publication date: Available online 28 October 2017 Source:American Heart Journal Author(s): Cian P. McCarthy, John W. McEvoy, James L. Januzzi Coronary artery disease (CAD) remains a significant cause of morbidity and mortality around the world. Patients with stable CAD can have an unpredictable clinical trajectory, thus, additional tools to prognosticate risk in this cohort are warranted. In recent years, a wide range of biomarkers have been recognized for their diagnostic capabilities in patients with stable CAD, identifying those with obstructive disease who may require more intensive preventive therapies or even consi...
Source: American Heart Journal - October 29, 2017 Category: Cardiology Source Type: research

Determinants of radiation dose during right transradial access: Insights from the RAD-Matrix study
Conclusions In thecontext of the biggest radiation study conducted in patients undergoing trans-radial catheterization, the instrumented right arm arrangement close to the leg and greater upper leaded shield dimensions were associated with a lower operator radiation exposure. Our findings emphasize the importance of implementing simple preventive measures to mitigate the extra risks of radiation exposure with right radial as compared with femoral access. Graphical abstract (Source: American Heart Journal)
Source: American Heart Journal - October 29, 2017 Category: Cardiology Source Type: research

TEMPORARY REMOVAL: Systematic Review and Meta-Analysis of Endovascular and Surgical Revascularization for Patients with Chronic Lower Extremity Venous Insufficiency and Varicose Veins
Publication date: Available online 29 September 2017 Source:American Heart Journal Author(s): Sreekanth Vemulapalli, Kishan Parikh, Remy Coeytaux, Victor Hasselblad, Amanda McBroom, Abigail Johnston, Giselle Raitz, Matthew J. Crowley, Kathryn R Lallinger, W. Schuyler Jones, Gillian D. Sanders The publisher regrets that this article has been temporarily removed. A replacement will appear as soon as possible in which the reason for the removal of the article will be specified, or the article will be reinstated. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policie...
Source: American Heart Journal - October 27, 2017 Category: Cardiology Source Type: research

A Population Health Perspective on a Claims and Electronic Health Record-Based Tool to Screen for Suboptimal Medication Adherence
Publication date: Available online 24 October 2017 Source:American Heart Journal Author(s): Leah L. Zullig, Lesley H. Curtis (Source: American Heart Journal)
Source: American Heart Journal - October 25, 2017 Category: Cardiology Source Type: research

Use of Echocardiography in Outpatients with Chest Pain and Normal Resting Electrocardiograms Referred to Mayo Clinic Rochester
Conclusion Echocardiograms were performed in 1 in 4 referral outpatients with chest pain seen at Mayo Clinic Rochester. However, only 1 in 16 of these echocardiograms was performed in violation of the class III recommendation in the American College of Cardiology Foundation/American Heart Association guidelines for the management of stable angina. These unnecessary echocardiograms were almost always normal, and had little impact on clinical management. The rate of unnecessary echocardiograms could be decreased by eliminating preordering. Condensed Abstract This study examined the rate of echocardiography in patients referr...
Source: American Heart Journal - October 25, 2017 Category: Cardiology Source Type: research

Apixaban following acute coronary syndromes in patients with prior stroke: Insights from the APPRAISE-2 trial
Conclusions Patients with prior stroke are at higher risk for recurrent cardiovascular events post-ACS and had a differential risk/benefit profile with oral anticoagulation. (Source: American Heart Journal)
Source: American Heart Journal - October 25, 2017 Category: Cardiology Source Type: research

Towards personalized risk assessment in patients with chronic heart failure: Detailed temporal patterns of NT-proBNP, troponin T and CRP in the Bio-SHiFT study
Conclusions Temporal patterns representing evolution of level and rate of change in level of NT-proBNP and CRP, and long-term elevation of NT-proBNP were independently associated with adverse prognosis in CHF patients. Individual patterns of change and combining multiple biomarkers could carry value for prognostication and for therapy guidance. (Source: American Heart Journal)
Source: American Heart Journal - October 23, 2017 Category: Cardiology Source Type: research

Evaluation of the Safety and Efficacy of an Edoxaban-based Antithrombotic Regimen in Patients with Atrial Fibrillation Following Successful Percutaneous Coronary Intervention (PCI) with Stent Placement: Rationale and Design of the ENTRUST-AF PCI Trial
Publication date: Available online 23 October 2017 Source:American Heart Journal Author(s): Pascal Vranckx, Thorsten Lewalter, Marco Valgimigli, Jan G. Tijssen, Paul-Egbert Reimitz, Lars Eckardt, Hans-Joachim Lanz, Wolfgang Zierhut, Rüdiger Smolnik, Andreas Goette Background The optimal antithrombotic treatment after percutaneous coronary intervention (PCI) with stenting in patients with atrial fibrillation (AF) is unknown. In the ENGAGE AF-TIMI 48 trial, edoxaban was non-inferior to a vitamin-K antagonist (VKA) with respect to the prevention of stroke or systemic embolism and was associated with significantly lower ...
Source: American Heart Journal - October 23, 2017 Category: Cardiology Source Type: research

Mechanism for Temporal Changes in Exercise Capacity After Fontan Palliation: Role of Doppler Echocardiography
Conclusions Overall there was a temporal decline in peak V̇O2 that correlated with decline in Doppler SVI. In the patients who had Fontan conversion operation, there was a temporal improvement in peak V̇O2 that correlated with improvement in chronotropic index. (Source: American Heart Journal)
Source: American Heart Journal - October 22, 2017 Category: Cardiology Source Type: research

Association of insurance type with receipt of oral anticoagulation in insured patients with atrial fibrillation: A report from the American College of Cardiology NCDR PINNACLE registry
Conclusions In a contemporary US AF population, there was significant variation of OAC prescription across insurance plans, with the highest among private and Medicare insured patients. These differences may indicate that insurance plan, and its associated pharmacy benefits, affect the pace of diffusion of new therapies. (Source: American Heart Journal)
Source: American Heart Journal - October 22, 2017 Category: Cardiology Source Type: research

The Aortic Valve replAcemenT versus conservative treatment in Asymptomatic seveRe aortic stenosis (AVATAR trial): a protocol update
Publication date: Available online 14 October 2017 Source:American Heart Journal Author(s): Marko Banovic, Bernard Iung, Jozef Bartunek, Martin Penicka, Marc Vanderheyden, Filip Casselman, Guy van Camp, Serge Nikolic, Svetozar Putnik (Source: American Heart Journal)
Source: American Heart Journal - October 17, 2017 Category: Cardiology Source Type: research