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Resource utilization and outcome among patients with selective versus nonselective troponin testing
Conclusions Contemporary troponin testing is frequently nonselective. The non-ACS and ACS populations differ significantly regarding clinical characteristics, revascularization rates, and outcomes. Troponin elevation is a powerful predictor of 1-year mortality in non-ACS, this association reveals an opportunity for risk stratification and targeted therapy. Key Questions In patients with suspected acute coronary syndrome (ACS), troponin testing is effective for diagnosis and prognosis. However, troponin testing has now expanded to include patients without suspected ACS. This nonselective troponin testing has unknown consequ...
Source: American Heart Journal - February 23, 2018 Category: Cardiology Source Type: research

Is there a role for pharmacokinetic/pharmacodynamic-guided dosing for novel oral anticoagulants?
Publication date: May 2018 Source:American Heart Journal, Volume 199 Author(s): Noel Chan, Philip T. Sager, Jack Lawrence, Thomas's Ortel, Paul Reilly, Scott Berkowitz, Dagmar Kubitza, John Eikelboom, Jeffry Florian, Norman Stockbridge, Martin Rose, Robert Temple, Jonathan H. Seltzer The novel direct oral anticoagulants (NOACs) represent a major advance in oral anticoagulant therapy and are replacing vitamin K antagonists as the preferred options for many indications. Given in fixed doses without routine laboratory monitoring, they have been shown to be at least as effective in reducing thromboembolic stroke as dose-adjus...
Source: American Heart Journal - February 23, 2018 Category: Cardiology Source Type: research

Caffeine and Incidence of Dyspnea in Patients Treated with Ticagrelor
Publication date: Available online 16 February 2018 Source:American Heart Journal Author(s): Daniel Lindholm, Stefan James, Jonas Andersson, Oscar Ö. Braun, Susanne Heller, Peter Henriksson, Jörg Lauermann, Patrik Öhagen, Christoph Varenhorst (Source: American Heart Journal)
Source: American Heart Journal - February 16, 2018 Category: Cardiology Source Type: research

Angiotensin Receptor-Neprilysin Inhibitor Therapy in Heart Failure: An End that Justifies the Means
Publication date: Available online 15 February 2018 Source:American Heart Journal Author(s): Andrew P. Ambrosy, Eric J. Velazquez (Source: American Heart Journal)
Source: American Heart Journal - February 15, 2018 Category: Cardiology Source Type: research

Rationale and Methods of the Prospective Study of Biomarkers, Symptom Improvement, and Ventricular Remodeling During Sacubitril/Valsartan Therapy for Heart Failure (PROVE-HF)
Conclusions Results from the Prospective Study of Biomarkers, Symptom Improvement, and Ventricular Remodeling During Sacubitril/Valsartan Therapy for Heart Failure (PROVE-HF) will help establish a mechanistic understanding of ARNI therapeutic benefits and provide clinicians with clarity on how to interpret information on biomarkers during treatment (PROVE-HF ClinicalTrials.gov identifier: NCT02887183). Graphical abstract (Source: American Heart Journal)
Source: American Heart Journal - February 14, 2018 Category: Cardiology Source Type: research

The prognostic value of heart rate recovery in patients with coronary artery disease A systematic review and meta-analysis
Conclusion In CAD patients, delayed HRR is significantly associated with all-cause mortality. As exercise testing is performed routinely in CAD patients, HRR can be considered in monitoring exercise, still further research must investigate the addition of HRR in current risk scores. (Source: American Heart Journal)
Source: American Heart Journal - February 14, 2018 Category: Cardiology Source Type: research

Trends in the incidence and outcomes of patients with aortic stenosis hospitalization
Conclusion AS hospitalizations in the elderly increased significantly beyond that was expected from population growth. Many AS patients did not receive aortic valve intervention after hospitalization. Mortality among the treated patients improved significantly over time. (Source: American Heart Journal)
Source: American Heart Journal - February 14, 2018 Category: Cardiology Source Type: research

The relative benefits of claims and electronic health record data for predicting medication adherence trajectory
Conclusion EHR data can provide good predictions of adherence trajectory and therefore may be useful for providers seeking to deploy resource-intensive interventions. However, prior adherence information derived from claims is most predictive, and can supplement EHR data when it is available. (Source: American Heart Journal)
Source: American Heart Journal - February 13, 2018 Category: Cardiology Source Type: research

A population health perspective on a claims and electronic health record –based tool to screen for suboptimal medication adherence
Publication date: March 2018 Source:American Heart Journal, Volume 197 Author(s): Leah L. Zullig, Lesley H. Curtis (Source: American Heart Journal)
Source: American Heart Journal - February 13, 2018 Category: Cardiology Source Type: research

Prevalent Digoxin Use and Subsequent Risk of Death or Hospitalization in Ambulatory Heart Failure Patients with a Reduced Ejection Fraction – Findings from the HF-ACTION Randomized Controlled Trial
Conclusion Although digoxin use was associated with high-risk clinical features, the association between digoxin therapy and outcomes was dependent on the statistical methods used for multivariable adjustment. Clinical equipoise exists and additional prospective research is required to clarify the role of digoxin in contemporary clinical practice including its effects on functional capacity, quality of life, and long-term outcomes. (Source: American Heart Journal)
Source: American Heart Journal - February 11, 2018 Category: Cardiology Source Type: research

Dual Antiplatelet Therapy for Perioperative Myocardial Infarction Following CABG Surgery
Conclusion One-quarter of CABG patients who had perioperative MI were treated with DAPT. DAPT was not associated with a difference in MI, stroke, or mortality at 30 days, but was associated with fewer re-hospitalizations. Further studies are needed to determine the optimal antiplatelet regimen following perioperative MI. What is already known about this subject? Perioperative myocardial infarction portends poor outcome but optimal management is currently unclear. While dual antiplatelet therapy is standard of care for acute coronary syndrome, its role in perioperative myocardial infarction is unknown. What does this study ...
Source: American Heart Journal - February 11, 2018 Category: Cardiology Source Type: research

Trends and Outcomes of Cardiac Transplantation from Donors Dying of Drug Intoxication
Conclusion There has been a large increase in OHT donors who die of drug intoxication in the United States. OHT outcomes from these donors are similar to those dying from other mechanisms. These data have important implications for donor selection in context of the ongoing opioid epidemic. (Source: American Heart Journal)
Source: American Heart Journal - February 10, 2018 Category: Cardiology Source Type: research

Telemedicine Cardiovascular Risk Reduction in Veterans: The CITIES trial
Conclusion Despite increased access to pharmacist resources, we did not observe significant improvements in CVD risk for patients randomized to the intervention compared to education control over 12 months. However, the intervention may have positive impact among those who actively participate, particularly in the short-term. (Source: American Heart Journal)
Source: American Heart Journal - February 10, 2018 Category: Cardiology Source Type: research

Risk of Cardiovascular Events and Incident Atrial Fibrillation in Patients without Prior Atrial Fibrillation: Implications for Expanding the Indications for Anticoagulation
Conclusions Patients without diagnosed AF but with certain risk factors were at a particularly high cardiovascular risk and may require new prevention approaches. In addition to the ongoing trials, future trials in other high-risk populations, e.g., diabetes and chronic kidney disease may be warranted. (Source: American Heart Journal)
Source: American Heart Journal - February 10, 2018 Category: Cardiology Source Type: research

TEMPORARY REMOVAL: Early Impact of Guideline Publication on Angiotensin-Receptor Neprilysin Inhibitor Use among Patients Hospitalized for Heart Failure
Publication date: Available online 31 January 2018 Source:American Heart Journal Author(s): Nancy Luo, Nicholas G. Ballew, Emily C. O’Brien, Melissa A. Greiner, Pamela N. Peterson, Bradley G. Hammill, N. Chantelle Hardy, Warren K. Laskey, Paul A. Heidenreich, Chun-Lan Chang, Adrian F. Hernandez, Lesley H. Curtis, Robert J. Mentz, Gregg C. Fonarow (Source: American Heart Journal)
Source: American Heart Journal - February 8, 2018 Category: Cardiology Source Type: research

Left ventricular ejection fraction reassessment post –myocardial infarction: Current clinical practice and determinants of adverse remodeling
Conclusions Current practice of LVEF reassessment during the convalescent months post-MI is suboptimal despite a sizeable proportion of patients that undergo adverse LV remodeling. Targeting processes affecting low rates of LVEF reassessment may reduce missed care opportunities and ensure that patients consistently receive appropriate evidence-based and guideline-recommended care. (Source: American Heart Journal)
Source: American Heart Journal - February 6, 2018 Category: Cardiology Source Type: research

Rationale and design for the Vascular Outcomes study of ASA along with rivaroxaban in endovascular or surgical limb revascularization for peripheral artery disease (VOYAGER PAD)
Conclusions VOYAGER PAD is evaluating the efficacy of rivaroxaban added to background antiplatelet therapy to reduce major cardiovascular and limb ischemic vascular outcomes in the high-risk population of PAD patients undergoing peripheral revascularization. (Source: American Heart Journal)
Source: American Heart Journal - February 3, 2018 Category: Cardiology Source Type: research

Ultrahigh-resolution ultrasound characterization of access site trauma and intimal hyperplasia following use of a 7F sheathless guide versus 6F sheath/guide combination for transradial artery PCI: Results of the PRAGMATIC trial
Conclusions A 7F sheathless approach to TRA-PCI results in no more IMT and early or late RA trauma than a standard 6F sheath/guide combination, rendering the 7F sheathless technique an attractive option for complex TRA-PCI. (Source: American Heart Journal)
Source: American Heart Journal - February 3, 2018 Category: Cardiology Source Type: research

Comparison of adverse event and device problem rates for transcatheter aortic valve replacement and Mitraclip procedures as reported by the Transcatheter Valve Therapy Registry and the Food and Drug Administration postmarket surveillance data
Conclusions We demonstrated that natural language processing technology sorted through raw MAUDE data, allowing identification of the most common events associated with TAVR and Mitraclip procedures, and that MAUDE-derived event rates were not statistically significantly different from TVT event rates. This technology has important public health implications because it improves postmarket surveillance of implantable devices and permits rapid and early dissemination of vital information. (Source: American Heart Journal)
Source: American Heart Journal - February 3, 2018 Category: Cardiology Source Type: research

Changes in renal function in patients with atrial fibrillation: Efficacy and safety of the non –vitamin K antagonist oral anticoagulants
Publication date: Available online 4 January 2018 Source:American Heart Journal Author(s): Kazuo Miyazawa, Daniele Pastori, Gregory Y.H. Lip (Source: American Heart Journal)
Source: American Heart Journal - February 2, 2018 Category: Cardiology Source Type: research

Resource utilization and outcome among patients with selective vs. nonselective troponin testing
Conclusions Contemporary troponin testing is frequently nonselective. The non-ACS and ACS populations differ significantly regarding clinical characteristics, revascularization rates, and outcomes. Troponin elevation is a powerful predictor of 1-year mortality in non-ACS, this association reveals an opportunity for risk stratification and targeted therapy. Key questions In patients with suspected acute coronary syndrome (ACS), troponin testing is effective for diagnosis and prognosis. However, troponin testing has now expanded to include patients without suspected ACS. This nonselective troponin testing has unknown consequ...
Source: American Heart Journal - February 1, 2018 Category: Cardiology Source Type: research

Early impact of guideline publication on angiotensin-receptor Neprilysin inhibitor use among patients hospitalized for heart failure
Conclusions and relevance The model suggested a small increase in ARNI use in heart failure patients being discharged from the hospital immediately after guideline release. However, the publication of national guidelines recommending ARNI use seemed to have little influence on the adoption of this evidence-based medication in the first 3 to 6months. (Source: American Heart Journal)
Source: American Heart Journal - February 1, 2018 Category: Cardiology Source Type: research

Transcatheter closure of patent foramen ovale following cryptogenic stroke: An updated meta-analysis of randomized controlled trials
Conclusions Transcatheter closure is associated with a significant reduction in the risk of stroke compared to medical management at the expense of an increased risk of atrial arrhythmias. (Source: American Heart Journal)
Source: American Heart Journal - February 1, 2018 Category: Cardiology Source Type: research

Effect of Carvedilol vs Metoprolol Succinate on Mortality in Heart Failure with Reduced Ejection Fraction
Conclusion Patients with HFrEF taking carvedilol had improved survival as compared to metoprolol succinate. The data supports the need for furthering testing to determine optimal choice of beta blockers in patients with heart failure with reduced ejection fraction. (Source: American Heart Journal)
Source: American Heart Journal - January 31, 2018 Category: Cardiology Source Type: research

The prognostic value of the relationship between right atrial and pulmonary capillary wedge pressure in diverse cardiovascular conditions
Conclusion In patients undergoing right catheterization for diverse indications, the mean RA and PCW pressures correlated moderately well, but there was discordance in a sizable minority, in whom assessment of left-sided filling pressures using estimated jugular venous pressure may be misleading. Elevated right atrial pressure is a marker for in-hospital mortality. (Source: American Heart Journal)
Source: American Heart Journal - January 31, 2018 Category: Cardiology Source Type: research

Utility of an additive frailty tests index score for mortality risk assessment following Transcatheter aortic valve replacement
Conclusions Frailty status and a higher frailty index score were associated with increased 1-year mortality risk following TAVR. (Source: American Heart Journal)
Source: American Heart Journal - January 31, 2018 Category: Cardiology Source Type: research

Rationale and design of the comParIson Of sacubitril/valsartaN versus Enalapril on Effect on nt-pRo-bnp in patients stabilized from an acute Heart Failure episode (PIONEER-HF) trial
Conclusion The PIONEER-HF trial will inform clinical practice by providing evidence on the safety, tolerability and efficacy of in-hospital initiation of sacubitril/valsartan among patients who have been stabilized following an admission for acute decompensated HF with a reduced EF. (Source: American Heart Journal)
Source: American Heart Journal - January 17, 2018 Category: Cardiology Source Type: research

Shared Decision-Making Tool for Thromboprophylaxis in Atrial Fibrillation – A Feasibility Study
Conclusions A shared decision-making interaction, facilitated by an AFSDM can significantly improve multiple measures of decision-making quality, leading to improved medication adherence and patient satisfaction. (Source: American Heart Journal)
Source: American Heart Journal - January 17, 2018 Category: Cardiology Source Type: research

The Optimal Anti-Coagulation for Enhanced-Risk Patients Post –Catheter Ablation for Atrial Fibrillation (OCEAN) trial
The objective was to assess whether rivaroxaban is superior to acetylsalicylic acid (ASA) in reducing the risk of clinically overt stroke, systemic embolism, or covert stroke among patients without apparent recurrent atrial arrhythmias for at least 1 year after their most recent AF ablation procedure. Methods/design A prospective, multicenter, open-label, randomized trial with blinded assessment of outcomes is under way (NCT02168829). Atrial fibrillation patients with at least 1 stroke risk factor (as defined by the CHA2DS2-VASc score) and without known atrial arrhythmia recurrences for at least 12 months after ablation ar...
Source: American Heart Journal - January 17, 2018 Category: Cardiology Source Type: research

Permanent Pacemaker Use Among Patients With Heart Failure and Preserved Ejection Fraction: Findings From the ADHERE National Registry
Conclusions Use of permanent pacemakers is relatively common among patients with heart failure with preserved ejection fraction. (Source: American Heart Journal)
Source: American Heart Journal - January 10, 2018 Category: Cardiology Source Type: research

Investigation of Motivational Interviewing and Prevention Consults to Achieve Cardiovascular Targets (IMPACT) trial
Conclusions Although non-HDL-C reduction at six months following a non-urgent CV procedure was not significant in the overall cohort, an increased uptake in high potency statins may translate into improved long-term health outcomes and cost reductions. (Source: American Heart Journal)
Source: American Heart Journal - January 10, 2018 Category: Cardiology Source Type: research

Thirty-Day Readmissions: Notes from the Primordial Era of Health Care Metrics
Publication date: Available online 8 January 2018 Source:American Heart Journal Author(s): Marvin A. Konstam (Source: American Heart Journal)
Source: American Heart Journal - January 9, 2018 Category: Cardiology Source Type: research

Rationale and Design of the Statins Evaluation in Coronary procedUres and REvascularization: The SECURE-PCI Trial
Publication date: Available online 8 January 2018 Source:American Heart Journal Author(s): Otavio Berwanger, Pedro G.M. de Barros e Silva, Frederico Toledo Campo Dall Orto, Pedro Beraldo de Andrade, Igor Ribeiro de Castro Bienert, Carlos Eduardo Bosso, José Mangione, Carisi Anne Polanczyk, Amanda Sousa, Renato Kalil, Luciano de Moura Santos, Andrei C. Sposito, Rafael L. Rech, Antonio Carlos Sobral Sousa, Felipe Baldissera, Bruno Ramos Nascimento, Isabella de Andrade Jesuíno, Eliana Vieira Santucci, Lucas Petri Daminani, Ligia N Laranjeira, Juliana A Borges de Oliveira, Roberto R Giraldez, Alexandre Biasi Cav...
Source: American Heart Journal - January 9, 2018 Category: Cardiology Source Type: research

A Hospital Level Analysis of 30-Day Readmission Performance for Heart Failure Patients and Long-Term Survival: Findings from Get With The Guidelines-Heart Failure
Conclusion Hospital performance on 30-day readmissions in HF has no or little association with risk adjusted 3-year mortality or median survival. There is a compelling need to utilize more meaningful and patient-centered outcome measures for reporting and incentivizing quality care for HF. (Source: American Heart Journal)
Source: American Heart Journal - January 9, 2018 Category: Cardiology Source Type: research

Temporal changes in radial access use, associates and outcomes in patients undergoing PCI using rotational atherectomy between 2007 and 2014: results from the British Cardiovascular Intervention Society national database
Conclusions In contemporary practice, radial access for PCI-ROTA results in similar procedural success when compared to femoral access but is associated with shorter length of stay, and lower rates of vascular complication, major bleeding and transfusion. (Source: American Heart Journal)
Source: American Heart Journal - January 8, 2018 Category: Cardiology Source Type: research

Efficacy and Safety of Dabigatran Compared with Warfarin in Patients with Atrial Fibrillation in Relation to Renal Function Over Time – A RE-LY trial analysis
Conclusions In AF, WRF was associated with a higher risk of death and major bleeding. The efficacy and safety profile of dabigatran compared to warfarin was similar irrespective of renal function changes over time. Dabigatran 110 mg showed a greater relative risk reduction of major bleeding in patients with normal renal function during follow-up. (Source: American Heart Journal)
Source: American Heart Journal - January 6, 2018 Category: Cardiology Source Type: research

High-sensitivity cardiac troponin T, left ventricular function, and outcome in non –ST elevation acute coronary syndrome
Conclusions Hs-cTnT levels provide incremental prognostic value independent of the LVEF in patients with NSTE-ACS. Hs-cTnT is particularly predictive for MACE in patients with severely depressed LVEF but also in those with a normal LVEF. Accordingly, a normal LVEF should not be used as an argument not to target patients to thorough workup. (Source: American Heart Journal)
Source: American Heart Journal - January 6, 2018 Category: Cardiology Source Type: research

Nonprimary PCI at hospitals without cardiac surgery on-site: Consistent outcomes for all?
Conclusions The noninferiority of nonprimary PCI at non-SoS hospitals was consistent across clinically relevant subgroups. Elective PCI at an SoS hospital conferred a TVR benefit which may be related to a lower rate of referral for diagnostic catheterization for reasons other than myocardial infarction. (Source: American Heart Journal)
Source: American Heart Journal - January 6, 2018 Category: Cardiology Source Type: research

Design of DISCO —Direct or Subacute Coronary Angiography in Out-of-Hospital Cardiac Arrest study
Conclusion This randomized clinical study will evaluate the effect of immediate coronary angiography after OHCA on 30-day survival in patients without ST elevation on their first recorded ECG. (Source: American Heart Journal)
Source: American Heart Journal - January 6, 2018 Category: Cardiology Source Type: research

Government Continues to Have an Important Role in Promoting Cardiovascular Health
Publication date: Available online 3 January 2018 Source:American Heart Journal Author(s): Gordon Tomaselli, William H. Roach, Ileana L. Piña, Matthew E. Oster, William H. Dietz, Katie Horton, William B. Borden, Kelly Brownell, Raymond J. Gibbons, Jennifer J. Otten, Christopher S. Lee, Charles Hill, Paul A. Heidenreich, David S. Siscovick, Laurie P. Whitsel Government investment has facilitated remarkable advances in cardiovascular science and medicine. It is vitally important that government engagement and investment continue as the US population faces unprecedented rates of obesity, diabetes, hypertension, sedent...
Source: American Heart Journal - January 4, 2018 Category: Cardiology Source Type: research

Changes in renal function in patients with atrial fibrillation: efficacy and safety of the non-vitamin K antagonist oral anticoagulants
Publication date: Available online 4 January 2018 Source:American Heart Journal Author(s): Kazuo Miyazawa, Daniele Pastori, Gregory Y.H. Lip (Source: American Heart Journal)
Source: American Heart Journal - January 4, 2018 Category: Cardiology Source Type: research

Changes in glomerular filtration rate and outcomes in patients with atrial fibrillation
Conclusions Rates of IS/TE, mortality and bleeding increased with worsening eGFR >4.81 ml/min/1.73 m2. Worsening eGFR was an independent predictor of IS/TE and of bleeding, and a better predictor of IS/TE than renal impairment in AF. (Source: American Heart Journal)
Source: American Heart Journal - December 31, 2017 Category: Cardiology Source Type: research

Effects of hyperoxia on myocardial injury following cardioversion —A randomized clinical trial
Conclusion Direct current cardioversion of atrial fibrillation/flutter with and without high-flow oxygen supplement was not associated with myocardial injury evaluated by high sensitive myocardial biomarkers. (Source: American Heart Journal)
Source: American Heart Journal - December 29, 2017 Category: Cardiology Source Type: research

Temporal trends in patient referral for Transcatheter aortic valve replacement and reasons for exclusion at a high-volume Center in the United States
Conclusions Referral numbers have been robust since TAVR became available. The percentage of patients excluded from TAVR has decreased over time. Patients are most commonly excluded from TAVR for concomitant coronary artery disease (CAD), asymptomatic severe AS, moderate AS, or non-cardiac critical illness. Patients with CAD and those with asymptomatic severe AS or moderate AS should be a focus for continued research in TAVR. (Source: American Heart Journal)
Source: American Heart Journal - December 29, 2017 Category: Cardiology Source Type: research

Impact of Hormone Therapy on Medicare Spending in the Women ’s Health Initiative Randomized Clinical Trials
Conclusions Menopausal hormone therapy increased spending for some diseases, but decreased spending for others. These offsetting effects led to modest (3% to 4%), non-significant increases in overall spending among women aged 65 years and older. (Source: American Heart Journal)
Source: American Heart Journal - December 27, 2017 Category: Cardiology Source Type: research

Knowledge to action: Rationale and design of the patient-centered care transitions in heart failure (PACT-HF) stepped wedge cluster randomized trial
Conclusions This protocol describes the implementation and testing of a transitional care model comprising health care services informed by high-level evidence. The study adopts an iKT and pragmatic approach, uses a robust study design, links clinical trial data with outcomes held in administrative databases, and includes patient-reported outcomes. Findings will have implications on clinical practice, health care policy, and Knowledge Translation (KT) research methodology. (Source: American Heart Journal)
Source: American Heart Journal - December 27, 2017 Category: Cardiology Source Type: research

Symptomatic Event Reduction with Extended-Duration Betrixaban in Acute Medically Ill Hospitalized Patients
Conclusion In an mITT analysis of all patients administered study drug, extended duration betrixaban reduced the primary endpoint as well as symptomatic events. In an as treated analysis, 80 mg of betrixaban reduced VTE related death. (Source: American Heart Journal)
Source: American Heart Journal - December 27, 2017 Category: Cardiology Source Type: research

Preoperative factors associated with worsening in health-related quality of life following coronary artery bypass grafting in the ROOBY trial
Conclusions Among VA patients, less than 20% experienced worse HRQL 1year after CABG. For patients with low symptom burden at baseline, diabetes, smoking, depression, PVD, COPD, and a prior stroke, clinicians should be more cautious in pre-CABG counseling as to their anticipated HRQL improvements. (Source: American Heart Journal)
Source: American Heart Journal - December 25, 2017 Category: Cardiology Source Type: research

ASCEND: A Study of Cardiovascular Events iN Diabetes: Characteristics of a randomized trial of aspirin and of omega-3 fatty acid supplementation in 15,480 people with diabetes
Conclusions Demonstrating that prophylactic aspirin safely reduces the risk of CVD or cancer in the primary prevention setting, or that omega-3 FA supplementation prevents CVD, would be relevant to hundreds of millions of people worldwide who are currently not receiving such therapies. The results of ASCEND will be reported in 2018. (Source: American Heart Journal)
Source: American Heart Journal - December 25, 2017 Category: Cardiology Source Type: research

Outcomes of Hospitalization in Adults with Fontan Palliation: The Mayo Clinic Experience
Conclusions Adults with Fontan palliation had more frequent hospitalization and in-hospital mortality compared to the rest of the CHD population. Arrhythmia and heart failure were the most common indications for hospitalization. Perhaps optimal management of heart failure and arrhythmia may improve outcomes in this population. (Source: American Heart Journal)
Source: American Heart Journal - December 25, 2017 Category: Cardiology Source Type: research