Log in to search using one of your social media accounts:

 

Outcomes of cervical laminoplasty —Population-level analysis of a national longitudinal database
Conclusions Our national analysis of cervical laminoplasty found the procedure to be clinically effective with low complication rates and postoperative symptomatic improvement. (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - November 16, 2017 Category: Neuroscience Source Type: research

Haemorrhagic intramedullary spinal cord lesion
Publication date: Available online 15 November 2017 Source:Journal of Clinical Neuroscience Author(s): Andrew J. Catran, Muhammad Fahmi Abdul Jalil (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - November 16, 2017 Category: Neuroscience Source Type: research

Outcomes of thoracic discectomy: A single center retrospective series
Publication date: Available online 15 November 2017 Source:Journal of Clinical Neuroscience Author(s): Michael Cloney, Benjamin Hopkins, Ekamjeet Dhillon, Nader S Dahdaleh (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - November 16, 2017 Category: Neuroscience Source Type: research

Mechanism hypotheses for the electrophysiological manifestations of two cases of endplate acetylcholinesterase deficiency related congenital myasthenic syndrome
Conclusions The change patterns of CMAP and R-CMAP, in combination with other electrophysiological features are very useful for the diagnosis of EAD related CMS, especially in predicting the presence of correct gene mutations. (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - November 15, 2017 Category: Neuroscience Source Type: research

Radiation exposure with hybrid image-guidance-based minimally invasive transforaminal lumbar interbody fusion
Publication date: Available online 11 November 2017 Source:Journal of Clinical Neuroscience Author(s): Michael M. Safaee, Taemin Oh, Murat Pekmezci, Aaron J. Clark The transforaminal lumbar interbody fusion (TLIF) is used for the treatment of back and leg pain secondary to spinal stenosis, degenerative disc disease, and spondylolisthesis. Minimally invasive surgery (MIS) is associated with less estimated blood loss (EBL), decreased length of stay, lower infection rates, and similar outcomes compared to the traditional TLIF. Fluoroscopy time has been reported with MIS-TLIF, but there are limited data on specific radiation ...
Source: Journal of Clinical Neuroscience - November 11, 2017 Category: Neuroscience Source Type: research

Neurenteric cyst at the dorsal craniocervical junction in a child: Case report
Publication date: Available online 11 November 2017 Source:Journal of Clinical Neuroscience Author(s): Pui Man Rosalind Lai, Mohamed A. Zaazoue, Roosevelt Francois, Daniel G. Dupervil, Aaron L. Berkowitz, Sanda Alexandrescu, Mark R. Proctor Neurenteric cysts, also known as enterogenous cysts, are uncommon, benign, congenital lesions that usually occur in the posterior mediastinum but can be seen at any level of the neuraxis. Here, we report a pediatric patient with a neurenteric cyst in the dorsal craniocervical junction as the only third reported pediatric case in the literature in this rare location, and describe the cl...
Source: Journal of Clinical Neuroscience - November 11, 2017 Category: Neuroscience Source Type: research

Spinobulbar muscular atrophy combined with atypical hereditary neuropathy with liability to pressure palsy
We report a case of co-existence of SBMA and atypical HNPP with genetic confirmation of CAG expansion in the androgen receptor (AR) gene and deletion of the peripheral myelin protein 22 (PMP22) gene. A 62-year-old man presented with progressive muscle weakness, fasciculations in upper and lower limbs and dysesthesia predominantly in the distal regions. No family members, including his children, experienced similar symptoms. The electrodiagnostic examination was compatible with demyelinating sensorimotor polyneuropathy. Simultaneous hereditary polyneuropathy and motor neuron disease were suspected and relevant genetic testi...
Source: Journal of Clinical Neuroscience - November 11, 2017 Category: Neuroscience Source Type: research

Serum anti-aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder presenting as acute eosinophilic encephalomyelitis
We report the case of a 57-year-old man with neuromyelitis optica spectrum disorder (NMOSD) presenting as acute eosinophilic encephalomyelitis. Magnetic resonance imaging revealed central nervous system lesions typical of NMOSD and anti-aquaporin-4 antibodies in the serum were identified; however, eosinophilia was evident in the cerebrospinal fluid (CSF) at the early stage of the disease. The number of eosinophils in the CSF decreased subsequently. Although activation of eosinophils is known to be an important factor in the development of NMOSD lesions, prominent eosinophilia in the CSF at the early stage of the disease ha...
Source: Journal of Clinical Neuroscience - November 11, 2017 Category: Neuroscience Source Type: research

Intraoperative definition of bottom-of-sulcus dysplasia using intraoperative ultrasound and single depth electrode recording – A technical note
We report on a patient with refractory epilepsy due to a BOSD, successfully resected with the aid of a multimodal surgical approach using neuronavigation based on MRI and PET, intraoperative ultrasound (iUS) and electrocorticography (ECoG) using depth electrodes. The lesion could be visualized on iUS showing an increase in echogenicity at the grey-white matter junction. IUS demonstrated the position of the depth electrode in relation to the lesion. Depth electrode recording showed almost continuous spiking. Thus, intraoperative imaging and electrophysiology helped confirm the exact location of the lesion. Post-resection ul...
Source: Journal of Clinical Neuroscience - November 11, 2017 Category: Neuroscience Source Type: research

Analysis on the risk factors of medication-overuse headache in Chinese patients
Conclusions The frequency of medicine overuse, Allodynia Symptom Checklist scores, anxiety disorder and lack or non-standardized preventive therapy were the independent risk factors for medication-overuse headache in patients with chronic migraine. (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - November 11, 2017 Category: Neuroscience Source Type: research

First line direct access for transarterial embolization of a dural arteriovenous fistula: Case report and literature review
We report an unusual anatomical variation, resulting in a DAVF forming between the superior sagittal sinus and an anomalous origin of the middle meningeal artery (MMA) arising from the left ophthalmic artery. We present an atypical case requiring mini-craniotomy for catheter access, as well as cannulation of extracranial arterial supply prior to embolization of a Cognard type IIa+b fistula. Due to structural variation, transarterial endovascular embolization was deemed too high risk owing to risk of permanent blindness. We present a technical note and literature review on the first documented case of combined endovascular ...
Source: Journal of Clinical Neuroscience - November 11, 2017 Category: Neuroscience Source Type: research

Increasing the safety of surgical treatment for complex Cranio-vertebral anomalies using customized 3D printed models
Publication date: Available online 9 November 2017 Source:Journal of Clinical Neuroscience Author(s): Kataria Rashim, K. Verma Pawan, V.D. Sinha Surgery for the Cranio-vertebral (CV) junction anomalies using top loading subocciput (C0)/C1-C2 screws is difficult and requires high level of skill and expertise. This is because of complex abnormal anatomy in that region and other issues including the instrumentation. Thorough knowledge of the 3D anatomy of the Craniovertebral junction of the patient is essential for favourable outcome. The customised 3D printed model of CV junction region of the patient can be used for studyi...
Source: Journal of Clinical Neuroscience - November 10, 2017 Category: Neuroscience Source Type: research

Considerations for general anaesthesia in Parkinson ’s disease
Publication date: Available online 10 November 2017 Source:Journal of Clinical Neuroscience Author(s): Daniel P. Roberts, Simon J.G. Lewis Parkinson’s disease is a common neurodegenerative disorder in the elderly which when present has a significant influence on surgical management. These patients necessitate additional perioperative and anaesthetic considerations across disease specific domains as well as in relation to the respiratory and cardiovascular systems. This brief review focuses on the factors which contribute to perioperative morbidity, including the use of medications that may exacerbate symptoms or adv...
Source: Journal of Clinical Neuroscience - November 10, 2017 Category: Neuroscience Source Type: research

Paraneoplastic neuromyelitis optica spectrum disorder: A case report and review of the literature
Publication date: Available online 10 November 2017 Source:Journal of Clinical Neuroscience Author(s): Ádám Annus, Krisztina Bencsik, Izabella Obál, Zsigmond Tamás Kincses, László Tiszlavicz, Romana Höftberger, László Vécsei Neuromyelitis optica spectrum disorders (NMOSD) are demyelinating, autoimmune diseases affecting the central nervous system. Typically, recurrent optic neuritis and longitudinal extensive transverse myelitis dominates the clinical picture. In most cases NMOSD are associated with autoantibodies targeting the water channel aquaporin-4 (...
Source: Journal of Clinical Neuroscience - November 10, 2017 Category: Neuroscience Source Type: research

Unusual case of progressive myelopathy
Publication date: Available online 10 November 2017 Source:Journal of Clinical Neuroscience Author(s): Enis D. Kocak, Jordan J. Jones, Nicholas F. Maartens (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - November 10, 2017 Category: Neuroscience Source Type: research

Diffusion tensor imaging and magnetic resonance spectroscopy in a patient with adult onset tuberous sclerosis complex
We presented a 43-year-old patient with TSC2 mutation, whose symptom was only incomplete quadrantic visual field deficit in spite of multiple brain tubers. The visual field deficit was thought to be due to a small lesion in the upper medial part of the optic radiation revealed by diffusion tensor imaging. Her brain tubers showed normal findings in magnetic resonance spectroscopy. Our case suggested that neurological and neuropsychiatric manifestations of TSC are affected by the quality rather than number of the lesions. In addition, MRS may be useful to identify the correlation between brain tubers and neurological disabil...
Source: Journal of Clinical Neuroscience - November 10, 2017 Category: Neuroscience Source Type: research

Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP): Integrating the literature on hereditary diffuse leukoencephalopathy with spheroids (HDLS) and pigmentary orthochromatic leukodystrophy (POLD)
This article presents a systematic review of ALSP in the context of two illustrative cases to help integrate the literature on HDLS and POLD. Consistent use of the term ALSP is suggested for clarity in the literature going forward. (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - November 7, 2017 Category: Neuroscience Source Type: research

Resolution of Anton –Babinski syndrome after systemic thrombolysis and mechanical thrombectomy with a stentriever
We present the case of a patient presenting with occlusion of both posterior cerebral arteries (PCA), with Anton–Babinski syndrome, completely solved after combined systemic thrombolysis and mechanical thrombectomy with a stent-retriever. (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - November 7, 2017 Category: Neuroscience Source Type: research

Acute treatment of stroke due to spontaneous calcified cerebral emboli causing large vessel occlusion
Conclusions Given the small sample reported in literature and no reported randomised studies, definitive recommendations could not be reached. However, considering thrombus composition, thrombolysis is most probably not sufficient and priority should be given to EVT. (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - November 6, 2017 Category: Neuroscience Source Type: research

Contralateral trigeminal neuralgia in a rapidly growing vestibular schwannoma: A case report
We present a rare case of vestibular schwannoma (VS) with contralateral trigeminal neuralgia. A 59 year-old woman presented with right-sided trigeminal neuralgia and a small VS in the left cerebellopontine angle (CPA) that was found via magnetic resonance imaging. The patient was administered medication; however, her symptoms gradually aggravated, and the size of the tumor increased. Two years after the initial diagnosis, the patient underwent surgical resection. After surgical resection, the patient’s facial pain was improved. The trigeminal neuralgia appeared to be related to brainstem displacement caused by the ...
Source: Journal of Clinical Neuroscience - November 6, 2017 Category: Neuroscience Source Type: research

REM sleep behavior disorder portends poor prognosis in Parkinson ’s disease: A systematic review
Publication date: Available online 6 November 2017 Source:Journal of Clinical Neuroscience Author(s): Yoon Kim, Young Eun Kim, Eun Ok Park, Chae Won Shin, Han-Joon Kim, Beomseok Jeon REM sleep behavior disorder (RBD) is a parasomnia wherein a loss of REM sleep atonia manifests as dream-enactment, often violent. Aside from its significance as a predictor of PD, RBD in PD may imply more than merely screaming at night and experiencing sleep fragmentation. To probe its significance as a prognostic factor in PD, we performed a systematic literature review. Analysis of prospective studies reveals baseline RBD confers a higher r...
Source: Journal of Clinical Neuroscience - November 6, 2017 Category: Neuroscience Source Type: research

Patient and treatment factors associated with survival among pediatric glioblastoma patients: A Surveillance, Epidemiology, and End Results study
Publication date: Available online 6 November 2017 Source:Journal of Clinical Neuroscience Author(s): Sandi Lam, Yimo Lin, Pascal Zinn, Jack Su, I-Wen Pan Glioblastoma (GBM) is a rare malignancy in children. The United States Surveillance, Epidemiology, and End Results (SEER) database allows large-scale analyses of clinical characteristics and prognostic features. We used it to study patients aged <20 years with histologically confirmed GBM (2000–2010) and examined the relationship between patient demographics, tumor characteristics, patterns of treatment, and outcomes. The primary outcome was disease-speci...
Source: Journal of Clinical Neuroscience - November 6, 2017 Category: Neuroscience Source Type: research

Endocrinal description of two Chinese Kennedy ’s disease pedigrees
Publication date: Available online 6 November 2017 Source:Journal of Clinical Neuroscience Author(s): Fang Li, Gulibositan Aji, Fei Leng, Jia-Chao Chen, Yu Luo, Jing Zhang, Ke Hu, Zi-Yun Cheng, Xi Xu, Zhi-Qiang Lu Kennedy’s disease (KD), also known as X-linked spinal and bulbar muscular atrophy (SBMA), is caused by the expansion of cytosine-adenine-guanine (CAG) repeats in the first exon of the androgen receptor (AR) gene. KD is a late-onset neural-endocrinal disease that is characterized by the degeneration of motor neurons in the brainstem and spinal cord. In addition, partial androgen insensitivity is an importan...
Source: Journal of Clinical Neuroscience - November 6, 2017 Category: Neuroscience Source Type: research

Comparison of the video head impulse test with the caloric test in patients with sub-acute and chronic vestibular disorders
In conclusion these results support the continued use of both vHIT and caloric tests in patients with sub-acute and chronic vestibular symptoms, especially if the vHIT is normal. (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - November 6, 2017 Category: Neuroscience Source Type: research

Fracture of fusion mass following anterior cervical plate removal: Case report
We describe the clinical presentation and operative management in the case of this rare and unexpected complication. (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - November 6, 2017 Category: Neuroscience Source Type: research

The view through the ventricle catheter – The new ShuntScope for the therapy of pediatric hydrocephalus
Conclusions Misplacements of shunt catheters are completely avoidable with the presented intra-catheter technique including slit ventricles or even aqueductal stenting. Potential complications can be avoided during revision surgery. The implementation of the ShuntScope is recommended in pediatric neurosurgery. (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - November 6, 2017 Category: Neuroscience Source Type: research

Colloid cyst and multiple meningiomata in Gorlin syndrome
Publication date: Available online 4 November 2017 Source:Journal of Clinical Neuroscience Author(s): Yan-Lin Li, Stephen Kai-Yan Kwok, Kenneth Chun-Kit Shiu A middle-aged man presented with syncope and confusion. Neuroimaging revealed a third ventricular mass with obstructive hydrocephalus and bilateral convexity meningiomata. The masses were excised and pathology showed a colloid cyst and WHO grade 1 meningiomata respectively. Multisystem workup confirmed Gorlin syndrome. To our knowledge, this is the fourth reported case of Gorlin syndrome associated with colloid cyst, and the first case where multiple meningiomata are...
Source: Journal of Clinical Neuroscience - November 5, 2017 Category: Neuroscience Source Type: research

Mycosis fungoides – A cutaneous lymphoproliferative disorder in a patient treated with fingolimod for multiple sclerosis
This report points to a possible association between fingolimod and skin lymphoproliferative disorder and emphasizes the need for periodic skin examination. (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - November 4, 2017 Category: Neuroscience Source Type: research

Clinical, electrophysiological, genetic, and imaging features of six Chinese Han patients with hereditary neuropathy with liability to pressure palsies (HNPP)
This study summarizes the clinical, electrophysiological, genetic, and imaging features of six unrelated Chinese Han patients with HNPP. Age of onset was within the second decade in five patients, and 46 years of age in one patient. Weakness or numbness in a unilateral lower extremity was the most common symptom in 5 patients, and bilateral sensorineural hearing loss was also detected in one patient. Electrophysiological presentations suggested demyelinating sensory-motor polyneuropathy in the group. Magnetic resonance imaging (MRI) of the cervical and lumbar spine revealed varying degrees of degeneration in five patient...
Source: Journal of Clinical Neuroscience - November 4, 2017 Category: Neuroscience Source Type: research

Three-dimensional gait analysis reveals dynamic alignment change in a patient with dropped head syndrome: A case report
Publication date: Available online 3 November 2017 Source:Journal of Clinical Neuroscience Author(s): Kousei Miura, Hideki Kadone, Masao Koda, Hiroshi Kumagai, Katsuya Nagashima, Kengo Fujii, Hiroshi Noguchi, Toru Funayama, Tetsuya Abe, Takeo Furuya, Masashi Yamazaki Dropped head syndrome (DHS) is a cervical kyphotic deformity caused by apparent weakness of the neck extensor muscles. We often encounter patients whose symptoms, including impaired forward vision and neck pain, deteriorate while walking. This is the first report of a case of dynamic spinal alignment change in a patient with DHS during walking using three-dim...
Source: Journal of Clinical Neuroscience - November 4, 2017 Category: Neuroscience Source Type: research

Dramatic psychiatric and behavioral symptoms following a subthalamic lesion
Publication date: Available online 4 November 2017 Source:Journal of Clinical Neuroscience Author(s): Byung Sun Choi, Guangxun Shen, Guangxian Nan, Jong-Min Kim, Ki-Young Jung, Beomseok Jeon Neuropsychiatric symptoms have been well documented after subthalamic nucleus deep brain stimulation (STN-DBS), but those following a subthalamic lesion have been rarely reported. Herein, we present a 43-year-old woman with sudden-onset dramatic psychiatric and behavioral symptoms with hemiballism. Brain magnetic resonance imaging (MRI) with fluid attenuated inversion recovery (FLAIR) sequence during the acute phase demonstrated exten...
Source: Journal of Clinical Neuroscience - November 4, 2017 Category: Neuroscience Source Type: research

Incidence of poststroke seizures: A meta-analysis
Conclusion Our results are relevant to the epidemiology of late-onset poststroke seizure, with 14 days being the ideal cutoff time point. The pooled incidence density of late-onset poststroke seizure was 1.12 per 100 person-years in 4 cohort studies. (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - November 4, 2017 Category: Neuroscience Source Type: research

Tumour stem cells in meningioma: A review
Publication date: Available online 4 November 2017 Source:Journal of Clinical Neuroscience Author(s): Ganeshwaran Shivapathasundram, Agadha C. Wickremesekera, Swee T. Tan, Tinte Itinteang Meningioma is a common intracranial and intraspinal neoplasm accounting for 25–30% of all primary neurological tumours. It is associated with high rates of recurrence especially in higher-grade tumours and lesions located at the skull base. Cancer stem cells are increasingly recognised as the origin of cancer and are attributed to loco-regional recurrence, metastasis and treatment resistance. This review presents the accumulating e...
Source: Journal of Clinical Neuroscience - November 4, 2017 Category: Neuroscience Source Type: research

Differences in blood pressure by measurement technique in neurocritically ill patients: A technological assessment
Publication date: Available online 4 November 2017 Source:Journal of Clinical Neuroscience Author(s): Abhijit V. Lele, Daren Wilson, Prabhakar Chalise, Jules Nazzaro, Vijay Krishnamoorthy, Monica S. Vavilala Blood pressure data may vary by measurement technique. We performed a technological assessment of differences in blood pressure measurement between non-invasive blood pressure (NIBP) and invasive arterial blood pressure (ABP) in neurocritically ill patients. After IRB approval, a prospective observational study was performed to study differences in systolic blood pressure (SBP), mean arterial pressure (MAP), and cereb...
Source: Journal of Clinical Neuroscience - November 4, 2017 Category: Neuroscience Source Type: research

A rare neurological complication of Waldenstrom ’s Macroglobulinemia
This report highlights a rare condition (WM) with a rare complication (bilateral facial nerve palsy) and illustrates the broad differential comprised by this presenting complaint. (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - November 4, 2017 Category: Neuroscience Source Type: research

Treatment decision for occipital arteriovenous malformations (AVMs) to achieve hemorrhagic control while maximizing visual preservation: Our experience and review of literature
Publication date: Available online 4 November 2017 Source:Journal of Clinical Neuroscience Author(s): Wuyang Yang, Jose L. Porras, Eunice Philadelphia, Jody Law, Tomas Garzon-Muvdi, Justin M. Caplan, Geoffrey P. Colby, Alexander L. Coon, Rafael J. Tamargo, Judy Huang Despite concern of hemorrhagic risk, patients with occipital AVMs are at significant risk for visual disturbances after treatment. We aim to characterize the hemorrhage risk and visual disturbance in occipital AVMs patients from our experience and literature review. We performed retrospective review of occipital AVM patients seen at our institution from 1990 ...
Source: Journal of Clinical Neuroscience - November 4, 2017 Category: Neuroscience Source Type: research

Hyperkinetic transient ischemic attacks preceding deep ganglionic infarction in a patient with a treated parasellar chondrosarcoma
Publication date: Available online 4 November 2017 Source:Journal of Clinical Neuroscience Author(s): Michael W. Ruff, Adip G. Bhargav, Stephen W. English, James P. Klaas A 44-year-old right-handed female with a past medical history of parasellar chondrosarcoma status post-surgical debulking and proton beam therapy (70 Gy) three years prior to presentation experienced several hours of brief, repetitive episodes of transient hemiballism and dystonia; this was followed by abrupt onset of fixed hemiparesis and dysarthria weeks later, ipsilateral to her prior hyperkinetic movements. She was found to have total occlusion of ...
Source: Journal of Clinical Neuroscience - November 4, 2017 Category: Neuroscience Source Type: research

Impact of academic facility type and volume on post-surgical outcomes following diagnosis of glioblastoma
Conclusions This study suggests that patients treated in Academic/Research programs and high patient-volume centers have increased survival and more favorable early-postsurgical outcomes. The extent to which differences in patient populations, socioeconomic factors, and/or provider expertise play into this cause will be areas of future research. (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - November 4, 2017 Category: Neuroscience Source Type: research

Holospinal epidural abscesses – Institutional experience
Conclusion Cervical instability occurred in half the patients who underwent cervical laminectomies without fusion, and there were no adverse outcomes in the patients who were fused in the setting of infection. For lower cervical abscess, upper thoracic laminectomy with catheter irrigation may be sufficient for decompression, minimizing risk of future instability. (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - November 4, 2017 Category: Neuroscience Source Type: research

Has acromegaly been diagnosed earlier?
Conclusion Regarding operated cases of GH-producing pituitary adenoma, acromegaly clinical manifestations tended to be milder at diagnosis in later years of the decade, and acromegaly was diagnosed at lower IGF-1 levels and in smaller lesions. Further study is mandatory for the generalization of this trend. (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - November 4, 2017 Category: Neuroscience Source Type: research

Improving the quality of the evidence – The necessity to lead by example
Publication date: December 2017 Source:Journal of Clinical Neuroscience, Volume 46 Author(s): Mary Simons, Kathryn Busch, Alberto Avolio, Hosen Kiat, Andrew Davidson Published systematic reviews and meta-analyses should comply with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses, or PRISMA checklist. Variable reporting of systematic reviews has recently led to a number of publications demonstrating a lack of compliance with PRISMA. Poor reporting compliance can lower researchers’ and clinicians’ ability to detect bias in published research and can also lead to impaired clinical decision-...
Source: Journal of Clinical Neuroscience - October 27, 2017 Category: Neuroscience Source Type: research

The effects of Christchurch earthquakes on anxiety and depression in Parkinson ’s disease patients
Publication date: December 2017 Source:Journal of Clinical Neuroscience, Volume 46 Author(s): Yassar Alamri (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - October 27, 2017 Category: Neuroscience Source Type: research

MicroRNA-21 promotes bone mesenchymal stem cells migration in vitro by activating PI3K/Akt/MMPs pathway
Publication date: December 2017 Source:Journal of Clinical Neuroscience, Volume 46 Author(s): Chen Lv, Shengwu Yang, Xin Chen, Xiongbai Zhu, Wenjun Lin, Lu Wang, Zhengxiang Huang, Mingyue Wang, Guanjun Tu MicroRNA-21 (miR-21) contributes to anti-apoptosis in bone marrow mesenchymal stem cells (BMSC), but its role in the migration of BMSCs remains vague. The aim of this study was to determine the possible effect of miR-21 on regulating BMSCs directional migration and the expression of MMP-2/MMP-9 in BMSCs in vitro. BMSCs were successfully infected with miR-21-up lentivirus. Cell migration using Transwell assay indicated th...
Source: Journal of Clinical Neuroscience - October 27, 2017 Category: Neuroscience Source Type: research

Oligomeric Proantho Cyanidins provides neuroprotection against early brain injury following subarachnoid hemorrhage possibly via anti-oxidative, anti-inflammatory and anti-apoptotic effects
Publication date: December 2017 Source:Journal of Clinical Neuroscience, Volume 46 Author(s): Guang-Xu Zhang, Jun Ma, Hu-Chen Lu, Zhen-Nan Ye, Jing Liu, Cheng-Bin Wang (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - October 27, 2017 Category: Neuroscience Source Type: research

Risk factors for neurological complications after operative treatment for schwannomas
Publication date: December 2017 Source:Journal of Clinical Neuroscience, Volume 46 Author(s): Taketsugu Fujibuchi, Joji Miyawaki, Teruki Kidani, Hiromasa Miura Schwannoma is a common benign soft tissue tumor. Although schwannomas can be theoretically enucleated without nerve damage, neurological complications occasionally develop following enucleation. The aim of this study was to elucidate the incidence of and risk factors for postoperative neurological complications following schwannoma enucleation. Ninety-eight schwannomas from 95 patients that were treated by surgical excision between January 2003 and December 2014 we...
Source: Journal of Clinical Neuroscience - October 27, 2017 Category: Neuroscience Source Type: research

High prevalence of small vessel disease long after cranial irradiation
In conclusion, small vessel disease is not a rare complication after cranial irradiation, even in young patients. Patients after cranial irradiation should be followed up with MR imaging including a hemosiderin-sensitive sequence. (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - October 27, 2017 Category: Neuroscience Source Type: research

Tumoral and stromal expression of Slug, ZEB1, and ZEB2 in brain metastasis
Publication date: December 2017 Source:Journal of Clinical Neuroscience, Volume 46 Author(s): Masaya Nagaishi, Satoshi Nakata, Yuko Ono, Koji Hirata, Yoshihiro Tanaka, Kensuke Suzuki, Hideaki Yokoo, Akio Hyodo Epithelial-to-mesenchymal transition (EMT) has an active role in the malignant progression of epithelial tumor cells. The aim of the study was to identify the existence of the EMT mechanism in brain metastasis. Tumors from 29 patients with brain metastases were assessed in terms of the immunoexpression of EMT-related factors including Slug, ZEB1, ZEB2, and E-cadherin in tumor cells and the surrounding mesenchymal st...
Source: Journal of Clinical Neuroscience - October 27, 2017 Category: Neuroscience Source Type: research

Decreased serum sodium levels predict symptomatic vasospasm in patients with subarachnoid hemorrhage
Conclusions: Symptomatic vasospasm occurs more often in older patients and affects outcomes. A decrease in serum sodium levels occurs a day before symptomatic vasospasm. This observation may help predict symptomatic vasospasm. (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - October 27, 2017 Category: Neuroscience Source Type: research

Clinical outcomes after craniotomy for unruptured intracranial aneurysm in patients with coronary artery disease
Conclusions Our results suggest that surgical complications and clinical outcomes after craniotomy may depend on the underlying reason for antiplatelet treatment. Moreover, a preoperative platelet count can be useful in predicting the occurrence of intracranial hemorrhage and severe morbidity after craniotomy in patients receiving antiplatelet agents. (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - October 27, 2017 Category: Neuroscience Source Type: research

Spinal stereotactic body radiotherapy in the United States: A decade-long nationwide analysis of patient demographics, practice patterns, and trends over time
In conclusion, SBRT for spine metastases in the United States has more than quadrupled in utilization over a recent ten-year span. Although the majority of spinal SBRT is multi-fraction, the most popular fractionation scheme was single-fraction. It has been most commonly used for Caucasian men under age 65 with private/Medicare insurance and no comorbidities. By far the most common origin of spinal metastases treated by SBRT was the lung, followed by renal cancer. These results provide a baseline for further prospective investigation. (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - October 27, 2017 Category: Neuroscience Source Type: research