Propensity Score-Matched Analysis of Lesion Patterns in Stroke Patients With Patent Foramen Ovale and Patients With Spontaneous Intracranial Artery Dissection

Conclusion: The present study suggests that lesion patterns observed from DWI of patients with PFO and SIAD might provide clues to the etiology of infarcts. Single lesions (cortical or subcortical) might be a typical feature of PFO associated strokes, while multiple lesions in one vascular territory might be a specific feature of SIAD associated strokes. Introduction Both patent foramen ovale (PFO) and spontaneous intracranial artery dissection (SIAD) are important stroke risk factors, especially in young and middle-aged adults (1–3). About 25% of patients with ischemic stroke are cryptogenic (4), and PFO is present in ~54% of patients with cryptogenic stroke under 54 yeas (5). PFO and SIAD might result in strokes through different mechanisms. Promptly identifying the difference in the underlying mechanisms among young and middle-aged stroke patients will facilitate selection of the best therapy for the primary disease and prevention of recurrent strokes. A prior study has assessed brain Magnetic resonance imaging (MRI) features of stroke patients due to PFO and SIAD and found that, a single non-territorial infarct seemed to favor strokes due to PFO, whereas territorial infarcts (with or without additional smaller lesions in the same territory) were more likely to occur in patients with arterial dissection (6). However, this study did not individually compare between patients with carotid dissection, vertebral dissection, and those with PFO, respectively, though ...
Source: Frontiers in Neurology - Category: Neurology Source Type: research

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Source: St. Michael's Hospital News and Media - Category: Hospital Management Tags: Hospital News Source Type: news
Publication date: Available online 26 January 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Melissa H. Siard-Altman, Patricia A. Harris, Amber D. Moffett-Krotky, Joanne L. Ireland, Alejandra Betancourt, Virginia D. Barker, Kellie E. McMurry, Stephanie E. Reedy, Amanda A. AdamsAbstractSimilarly to aged humans, senior horses (≥20 years) exhibit chronic low-grade inflammation systemically, known as inflamm-aging. Inflamm-aging in the senior horse has been characterized by increased circulating inflammatory cytokines as well as increased inflammatory cytokine production by lymphocytes and monocytes in resp...
Source: Veterinary Immunology and Immunopathology - Category: Veterinary Research Source Type: research
Publication date: Available online 26 January 2020Source: Radiation Physics and ChemistryAuthor(s): A. Bianchi, A. Selva, P. Colautti, D. Bortot, D. Mazzucconi, A. Pola, S. Agosteo, G. Petringa, G.A.P. Cirrone, B. Reniers, A. Parisi, L. Struelens, F. Vanhavere, V. ConteAbstractA sealed miniaturized Tissue Equivalent Proportional Counter (mini-TEPC) able to work in gas-steady modality was developed at the Legnaro National Laboratories of the Italian National Institute of Nuclear Physics (LNL – INFN, Legnaro, Italy).The aim of the present work is to compare the response of this mini-TEPC with that of a silicon microdos...
Source: Radiation Physics and Chemistry - Category: Physics Source Type: research
Alignment of a crystal with the coordinate system of a scanning electron microscope (SEM) is essential for obtaining controlled diffraction conditions or investigating anisotropic material properties. The computer program crystalAligner was developed to enable the weighted constrained alignment of one or two crystal directions in crystals of arbitrary orientation and structure with the coordinate system of a SEM. For a given set of crystal directions, alignment objectives and rotational constraints, the algorithm simulates the rotation of the crystal on any constrained SEM stage and minimizes the misalignment of the crysta...
Source: Journal of Applied Crystallography - Category: Physics Authors: Tags: scanning electron microscopy electron backscatter diffraction optimization computer programs Source Type: research
Multi-wavelength (mw) Bragg coherent X-ray diffraction imaging (BCDI) is demonstrated on a single Au particle. The multi-wavelength Bragg diffraction patterns are inverted using conventional phase-retrieval algorithms where the dilation of the effective pixel size of a pixelated 2D detector caused by the variation of the X-ray beam energy is mitigated by interpolating the raw data. The reconstructed Bragg electron density and phase field are in excellent agreement with the results obtained from conventional rocking scans of the same particle. Voxel sizes of about 63   nm3 are obtained for reconstructions from both approa...
Source: Journal of Applied Crystallography - Category: Physics Authors: Tags: Bragg coherent X-ray diffraction imaging Au nanoparticles energy scanning research papers Source Type: research
Analytical expressions for Gaussian-beam Z-scan and eclipsing Z-scan signals are obtained in a unified format in the case of third-order ...
Source: Journal of the Optical Society of America B - Category: Physics Authors: Source Type: research
ConclusionExndin-4 can alleviate diabetes-caused damage to mice, moreover, it reduced endoplasmic reticulum stress and ROS through inhibiting p38 MAPK pathway in MPCs cells under high-glucose condition, thus increasing cell viability and reducing cell apoptosis.
Source: Molecular and Cellular Probes - Category: Molecular Biology Source Type: research
Publication date: 15 April 2020Source: Journal of Molecular Structure, Volume 1206Author(s): Seyit Ali Güngör, Mehmet Tümer, Muhammet Köse, Sultan ErkanAbstractThe benzaldehyde derivatives (1–6) containing one and/or two propargyl arm(s) attached to the phenolic hydroxyl oxygen atom on the ortho-, meta- or para-positions of the aromatic ring were synthesized and characterized by spectral and microanalytical methods. The molecular structures were of 1, 4–6 determined by the single crystal X-ray crystallography. The benzaldehyde derivatives containing free phenolic groups involved intra- and i...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
CONCLUSION: UGH syndrome can be caused by any type of pseudophakic lens. An intraocular lens in the bag should not rule out the diagnosis. Despite the decreasing popularity of anterior chamber intraocular lens implantation, UGH syndrome remains a current condition and must be recognised in order to adapt therapeutic management. PMID: 31982180 [PubMed - as supplied by publisher]
Source: Journal Francais d Ophtalmologie - Category: Opthalmology Tags: J Fr Ophtalmol Source Type: research
Publication date: Available online 26 January 2020Source: Carbohydrate PolymersAuthor(s): Resmi Rajalekshmi, Parvathy Jayasree, John Annie, Joseph RoyAbstractInjectable in situ gelling hydrogels are viable treatment options for meniscal injuries occurring in athletes. The present study aims to develop an injectable hydrogel via borax complexation of oxidized alginate, followed by a self-crosslinking reaction with gelatin through a Schiff’s base reaction. Gelation kinetics and degree of crosslinking could be controlled by changing the concentration of components and the formation of Schiff's base formation was confir...
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
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