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Condition: Epilepsy
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Total 2623 results found since Jan 2013.
Association of Mortality and Risk of Epilepsy With Type of Acute Symptomatic Seizure After Ischemic Stroke
This cohort study examines data for patients with acute ischemic stroke to compare the risk of poststroke mortality and epilepsy between different types of acute symptomatic seizures.
Source: JAMA Neurology - April 10, 2023 Category: Neurology Source Type: research
ERLEADA ® (apalutamide), First-and-Only Next-Generation Androgen Receptor Inhibitor with Once-Daily, Single-Tablet Option, Now Available in the U.S.
HORSHAM, Pa., April 3, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced the availability of an additional tablet strength of ERLEADA® (apalutamide) in the United States. The introduction of the 240mg tablet provides the first-and-only option for a once-daily, single-tablet Androgen Receptor Inhibitor (ARI) approved for the treatment of patients with non-metastatic castration-resistant prostate cancer (nmCRPC) and for the treatment of patients with metastatic castration-sensitive prostate cancer (mCSPC).With two strengths available, healthcare professionals will have the flexibility to...
Source: Johnson and Johnson - April 3, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news
An update on the role of Hippo signaling pathway in ischemia-associated central nervous system diseases
Biomed Pharmacother. 2023 Mar 31;162:114619. doi: 10.1016/j.biopha.2023.114619. Online ahead of print.ABSTRACTThe most frequent reason of morbidity and mortality in the world, cerebral ischemia sets off a chain of molecular and cellular pathologies that associated with some central nervous system (CNS) disorders mainly including ischemic stroke, Alzheimer's disease (AD), Parkinson's disease (PD), epilepsy and other CNS diseases. In recent times, despite significant advancements in the treatment of the pathological processes underlying various neurological illnesses, effective therapeutic approaches that are specifically ta...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 2, 2023 Category: Drugs & Pharmacology Authors: Xuan Wei Guangshan Huang Jiyong Liu Jinwen Ge Wenli Zhang Zhigang Mei Source Type: research
Association of Dementia Risk With Focal Epilepsy and Modifiable Cardiovascular Risk Factors
This cross-sectional study examines data from the UK Biobank to explore the association between focal epilepsy compared with stroke or migraine and the risk of developing dementia and how that risk is affected by modifiable cardiovascular risk factors.
Source: JAMA Neurology - March 27, 2023 Category: Neurology Source Type: research
Neutrophil to lymphocyte ratio is associated with the epilepsy after primary intracerebral hemorrhage
CONCLUSION: High NLR at admission is associated with an increased risk of PSE, which suggests that NLR may play a role in risk stratification in patients with ICH.PMID:36963316 | DOI:10.1016/j.yebeh.2023.109177
Source: Epilepsy and Behaviour - March 24, 2023 Category: Neurology Authors: Mengqi Lin Ru Lin Dongqin Zhu Yuhuan Wu Lufei Feng Weizeng Su Weilei He Source Type: research
A response to the letter about the article ‘Clinical features of epileptic seizures in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes’
Dear Editor
Source: Seizure: European Journal of Epilepsy - March 23, 2023 Category: Neurology Authors: Xiaxin Yang, Xiuhe Zhao Source Type: research
Contribution of nuclear medicine to the diagnosis and management of primary brain tumours
Rev Neurol (Paris). 2023 Mar 16:S0035-3787(23)00874-3. doi: 10.1016/j.neurol.2023.03.002. Online ahead of print.ABSTRACTPositron emission tomography (PET) is a powerful tool that can help physicians manage primary brain tumours at diagnosis and follow-up. In this context, PET imaging is used with three main types of radiotracers: 18F-FDG, amino acid radiotracers, and 68Ga conjugated to somatostatin receptor ligands (SSTRs). At initial diagnosis, 18F-FDG helps to characterize primary central nervous system (PCNS) lymphomas and high-grade gliomas, amino acid radiotracers are indicated for gliomas, and SSTR PET ligands are in...
Source: Revue Neurologique - March 18, 2023 Category: Neurology Authors: T Horowitz E Tabouret T Graillon B Salgues O Chinot A Verger E Guedj Source Type: research
BCI-activated electrical stimulation in children with perinatal stroke and hemiparesis: A pilot study
ConclusionBrain computer interface-FES was well -tolerated and feasible in children with hemiparesis. This paves the way for clinical trials to optimize approaches and test efficacy.
Source: Frontiers in Human Neuroscience - March 17, 2023 Category: Neuroscience Source Type: research
Acori Tatarinowii Rhizoma: A comprehensive review of its chemical composition, pharmacology, pharmacokinetics and toxicity
Acori Tatarinowii Rhizoma (ATR, Shi Chang Pu in Chinese), a natural product with multiple targets in various diseases. This review provides the comprehensive summary of the chemical composition, pharmacological effects, pharmacokinetics parameters and toxicity of ATR. The results indicated that ATR possesses a wide spectrum of chemical composition, including volatile oil, terpenoids, organic acids, flavonoids, amino acids, lignin, carbohydrates and so on. Accumulating evidence from various studies has shown that ATR exerts a wide range of pharmacological properties, including protecting nerve cells, alleviating learning an...
Source: Frontiers in Pharmacology - March 16, 2023 Category: Drugs & Pharmacology Source Type: research
Clinical Biomarkers and Prediction Models for Poststroke Epilepsy: Have We Settled the Scores Yet?
In an era of time-dependent reperfusion and recanalization therapy for stroke leading to improved survival, there is a growing population at risk of poststroke epilepsy (PSE). Accumulating evidence suggests a multidirectional interaction among stroke, PSE, and dementia in stroke survivors. There is no evidence to justify prophylactic antiseizure medication (ASM) to reduce these morbidities. Although several predictive molecular biomarkers and scoring models have been proposed, they remain inadequately validated for stratifying risk and indicating who will benefit from prophylactic ASM. Studies leveraging advances in geneti...
Source: Neurology Clinical Practice - March 14, 2023 Category: Neurology Authors: Yonas, A. S., Meschia, J. F., Feyissa, A. M. Tags: Stroke in young adults, All Cerebrovascular disease/Stroke, EEG; see Epilepsy/Seizures, Screening in epidemiology, All Epilepsy/Seizures Commentary Source Type: research
