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Condition: Epilepsy

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Total 2623 results found since Jan 2013.

Bone Marrow-Derived Mononuclear Cells in the Treatment of Neurological Diseases: Knowns and Unknowns
Cell Mol Neurobiol. 2023 Jun 25. doi: 10.1007/s10571-023-01377-x. Online ahead of print.ABSTRACTBone marrow-derived mononuclear cells (BMMNCs) have been used for decades in preclinical and clinical studies to treat various neurological diseases. However, there is still a knowledge gap in the understanding of the underlying mechanisms of BMMNCs in the treatment of neurological diseases. In addition, prerequisite factors for the efficacy of BMMNC administration, such as the optimal route, dose, and number of administrations, remain unclear. In this review, we discuss known and unknown aspects of BMMNCs, including the cell ha...
Source: Cellular and Molecular Neurobiology - June 25, 2023 Category: Cytology Authors: Quyen Thi Nguyen Liem Nguyen Thanh Van T Hoang Trang T K Phan Michael Heke Duc M Hoang Source Type: research

Editorial comment on “Development and validation of a novel radiomics-clinical model for predicting post-stroke epilepsy after first-ever intracerebral haemorrhage”
Source: European Radiology - June 24, 2023 Category: Radiology Source Type: research

The natural history of epilepsy and nonepileptic seizures in Sturge-Weber syndrome: A retrospective case-note review
This study explored the natural history of epileptic and nonepileptic seizures into adulthood in patients with SWS, and their treatment, and investigated whether any clinical factors predict which symptoms a patient will experience during adulthood.METHODS: A retrospective case-note review of a cohort of 26 adults with SWS at the National Hospital for Neurology and Neurosurgery (NHNN). Childhood data were also recorded, where available, to enable review of change/development of symptoms over time.RESULTS: The course of epilepsy showed some improvement in adulthood - seventeen adults continued to have seizures, while six pa...
Source: Epilepsy and Behaviour - June 22, 2023 Category: Neurology Authors: Rhian Male Sofia H Eriksson Source Type: research

Effectiveness and Safety of Lacosamide, A Third-generation Anti-seizure Medication, for Poststroke Seizure and Epilepsy: A Literature Review
Curr Neuropharmacol. 2023 Jun 20. doi: 10.2174/1570159X21666230616114255. Online ahead of print.ABSTRACTAdvances in stroke treatment have resulted in a dramatic reduction in stroke mortality. Nevertheless, poststroke seizures and epilepsy are issues of clinical importance affecting survivors. Additionally, stroke is the most common cause of epilepsy in older adults. Although numerous antiseizure medications exist, studies are needed to provide robust evidence of the efficacy and tolerability of these medicines for treating poststroke seizures and epilepsy. Crucially, the newer generations of antiseizure medications require...
Source: Epilepsy Curr - June 21, 2023 Category: Neurology Authors: Yu-Shiue Chen Ming-Chi Lai Tsang-Shan Chen Yung-Hsin Tseng Ya Jhen Li Chin-Wei Huang Source Type: research

Todd's paralysis due to hyperperfusion syndrome after carotid endarterectomy mimicking postoperative stroke
J Cardiovasc Surg (Torino). 2023 Jun 19. doi: 10.23736/S0021-9509.23.12720-0. Online ahead of print.ABSTRACTTodd's paralysis is a neurological deficit that is observed in <10% of patients following epileptic seizures. Cerebral hyperperfusion syndrome (CHS) is a rare complication following carotid endarterectomy (CEA), seen in 0-3% of the patients, characterized by focal neurological deficit, headache, disorientation, and sometimes seizures. In this case report, we present a case of CHS after CEA followed by seizures and Todd's paralysis that mimicked postoperative stroke. A 75-year-old female patient was admitted for CE...
Source: The Journal of Cardiovascular Surgery - June 19, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Slobodan Tanaskovic Nikola Cimbaljevic Jovan Petrovic Enes Ljatifi Mirjana Antonijevic Maja Neskovic Aleksandra Ostojic Nenad Ilijevski Source Type: research