Management of essential tremor deep brain stimulation-induced side effects
Deep brain stimulation (DBS) is an effective surgical therapy for carefully selected patients with medication refractory essential tremor (ET). The most popular anatomical targets for ET DBS are the ventral intermedius nucleus (VIM) of the thalamus, the caudal zona incerta (cZI) and the posterior subthalamic area (PSA). Despite extensive knowledge in DBS programming for tremor suppression, it is not uncommon to experience stimulation induced side effects related to DBS therapy. Dysarthria, dysphagia, ataxia, and gait impairment are common stimulation induced side effects from modulation of brain tissue that surround the ta...
Source: Frontiers in Human Neuroscience - February 22, 2024 Category: Neuroscience Source Type: research

Neuroimaging and neuromodulation of invisible symptoms in multiple sclerosis
(Source: Frontiers in Human Neuroscience)
Source: Frontiers in Human Neuroscience - February 22, 2024 Category: Neuroscience Source Type: research

Editorial: Advances in neuroimaging and its applications on biomedical devices
(Source: Frontiers in Human Neuroscience)
Source: Frontiers in Human Neuroscience - February 22, 2024 Category: Neuroscience Source Type: research

Case report: An N-of-1 study using amplitude modulated transcranial alternating current stimulation between Broca's area and the right homotopic area to improve post-stroke aphasia with increased inter-regional synchrony
Over one-third of stroke survivors develop aphasia, and language dysfunction persists for the remainder of their lives. Brain language network changes in patients with aphasia. Recently, it has been reported that phase synchrony within a low beta-band (14–19 Hz) frequency between Broca's area and the homotopic region of the right hemisphere is positively correlated with language function in patients with subacute post-stroke aphasia, suggesting that synchrony is important for language recovery. Here, we employed amplitude-modulated transcranial alternating current stimulation (AM-tACS) to enhance synchrony within the low...
Source: Frontiers in Human Neuroscience - February 22, 2024 Category: Neuroscience Source Type: research

Editorial: Immersive technology and ambient intelligence for assistive living, medical, and healthcare solutions
(Source: Frontiers in Human Neuroscience)
Source: Frontiers in Human Neuroscience - February 21, 2024 Category: Neuroscience Source Type: research

Proceedings of the 11th Annual Deep Brain Stimulation Think Tank: pushing the forefront of neuromodulation with functional network mapping, biomarkers for adaptive DBS, bioethical dilemmas, AI-guided neuromodulation, and translational advancements
The Deep Brain Stimulation (DBS) Think Tank XI was held on August 9–11, 2023 in Gainesville, Florida with the theme of “Pushing the Forefront of Neuromodulation”. The keynote speaker was Dr. Nico Dosenbach from Washington University in St. Louis, Missouri. He presented his research recently published in Nature inn a collaboration with Dr. Evan Gordon to identify and characterize the somato-cognitive action network (SCAN), which has redefined the motor homunculus and has led to new hypotheses about the integrative networks underpinning therapeutic DBS. The DBS Think Tank was founded in 2012 and provides an open platfo...
Source: Frontiers in Human Neuroscience - February 21, 2024 Category: Neuroscience Source Type: research

Human brain activity and functional connectivity associated with verbal long-term memory consolidation across 1 month
We examined whole-brain changes in retrieval-related brain activity, as well as functional connectivity of the hippocampus and ventromedial prefrontal cortex (vmPFC), as memories aged from 1 hour to 1 month. Secondary analyses minimized the effect of confounding factors affected by memory age (i.e., changes in confidence and response time or re-encoding of targets).ResultsMemory accuracy, confidence ratings, and response times changed with memory age. A memory age network was identified where retrieval-related brain activity in cortical regions increased or decreased as a function of memory age. Hippocampal brain activity ...
Source: Frontiers in Human Neuroscience - February 21, 2024 Category: Neuroscience Source Type: research

Effects of acute and long-term mindfulness on neural activity and the conflict resolution component of attention
This study recruited 20 experienced meditators and 20 novices and assigned them to a mindfulness or a control condition. They completed a Stroop Task to measure cognitive conflict resolution before and after the intervention, with brain activity monitored via functional near-infrared spectroscopy (fNIRS). Novices showed an age-related decline in conflict resolution ability, while experienced meditators didn’t. Initially, both groups showed similar Stroop performance, but experienced meditators had greater brain activation in the left dorsolateral prefrontal cortex (DLPFC). Post-intervention, novices in the breath count t...
Source: Frontiers in Human Neuroscience - February 21, 2024 Category: Neuroscience Source Type: research

Effects of speech rate modifications on phonatory acoustic outcomes in Parkinson ’s disease
Speech rate reduction is a global speech therapy approach for speech deficits in Parkinson’s disease (PD) that has the potential to result in changes across multiple speech subsystems. While the overall goal of rate reduction is usually improvements in speech intelligibility, not all people with PD benefit from this approach. Speech rate is often targeted as a means of improving articulatory precision, though less is known about rate-induced changes in other speech subsystems that could help or hinder communication. The purpose of this study was to quantify phonatory changes associated with speech rate modification acros...
Source: Frontiers in Human Neuroscience - February 21, 2024 Category: Neuroscience Source Type: research

Editorial: Coma and disorders of consciousness: an overview
(Source: Frontiers in Human Neuroscience)
Source: Frontiers in Human Neuroscience - February 20, 2024 Category: Neuroscience Source Type: research

AFM signal model for dysarthric speech classification using speech biomarkers
Neurological disorders include various conditions affecting the brain, spinal cord, and nervous system which results in reduced performance in different organs and muscles throughout the human body. Dysarthia is a neurological disorder that significantly impairs an individual's ability to effectively communicate through speech. Individuals with dysarthria are characterized by muscle weakness that results in slow, slurred, and less intelligible speech production. An efficient identification of speech disorders at the beginning stages helps doctors suggest proper medications. The classification of dysarthric speech assumes a...
Source: Frontiers in Human Neuroscience - February 20, 2024 Category: Neuroscience Source Type: research

Potentially modifiable risk and protective factors affecting mental and emotional wellness in pregnancy
ConclusionThese findings highlight the importance of assessing substance use, including periconceptional alcohol exposure, and mental health in pregnant persons as closely related risk factors which cannot be addressed in isolation. Our findings also emphasize a strong protective effect of socio-cultural factors on maternal mental and emotional wellbeing—a strong precursor to maternal-infant bonding and infant neurodevelopment. (Source: Frontiers in Human Neuroscience)
Source: Frontiers in Human Neuroscience - February 20, 2024 Category: Neuroscience Source Type: research

Children with bilateral cerebral palsy use their hip joint to complete a step-up task
Performance in stair-climbing is largely associated with disruptions to mobility and community participation in children with cerebral palsy (CP). It is important to understand the nature of motor impairments responsible for making stairs a challenge in children with bilateral CP to clarify underlying causes of impaired mobility. In pediatric clinical populations, sensitive measurements of movement quality can be captured during the initial step of stair ascent. Thus, the purpose of this study was to quantify the lower limb joint moments of children with bilateral CP during the stance phases of a step-up task. Participants...
Source: Frontiers in Human Neuroscience - February 20, 2024 Category: Neuroscience Source Type: research

Spatial tactile localization depends on sensorimotor binding: preliminary evidence from virtual reality
This study demonstrated the possibility of inducing spatial biases in the processing of bodily information by modulating the sensory-motor interaction between stimuli in virtual environments (while keeping constant the actual position of the body in space). (Source: Frontiers in Human Neuroscience)
Source: Frontiers in Human Neuroscience - February 20, 2024 Category: Neuroscience Source Type: research

Editorial: Multisensory speech in perception and production
(Source: Frontiers in Human Neuroscience)
Source: Frontiers in Human Neuroscience - February 19, 2024 Category: Neuroscience Source Type: research