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Condition: Septic Shock
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Total 242 results found since Jan 2013.
Electroconvulsive Therapy in a Patient With Moyamoya Syndrome
We report on a 30-year-old woman diagnosed with moyamoya syndrome resulting from sickle cell disease who developed catatonia and was successfully treated with electroconvulsive therapy (ECT). Neuroimaging revealed severe tandem narrowing of the left internal carotid artery with diminished cerebral blood flow, moderate narrowing of the right supraclinoid aspect of the right internal carotid artery, and associated numerous lenticulostriate collaterals bilaterally, consistent with moyamoya. The patient presented with mutism; posturing; immobility; stupor; withdrawal; refusal to eat, drink, or speak; and staring, supporting a ...
Source: The Journal of ECT - February 21, 2015 Category: Psychiatry Tags: Case Reports Source Type: research
Sepsis, septic shock, and fatal exertional heat stroke - Epstein Y, Roberts WO, Golan R, Heled Y, Sorkine P, Halpern P.
Exertional heat stroke (EHS) is a clinical syndrome of hyperthermia, encephalopathy, and multiorgan dysfunction that can be irreversible and fatal. While prompt recognition and immediate, aggressive total body cooling can prevent progression of the clinica...
Source: SafetyLit: All (Unduplicated) - January 23, 2015 Category: Global & Universal Tags: Environmental Issues, Climate, Geophysics Source Type: news
Dynamic arterial elastance predicts mean arterial pressure decrease associated with decreasing norepinephrine dosage in septic shock
IntroductionGradual reduction of the dosage of norepinephrine (NE) in patients with septic shock is usually left to the physician?s discretion. No haemodynamic indicator predictive of the possibility of decreasing the NE dosage is currently available at the bedside. The respiratory pulse pressure variation / respiratory stroke volume variation (dynamic arterial elastance (Eadyn)) ratio has been proposed as an indicator of vascular tone. The purpose of this study was to determine whether Eadyn can be used to predict the decrease in arterial pressure when decreasing the NE dosage in resuscitated septic patients.
Methods:
A p...
Source: Critical Care - January 19, 2015 Category: Intensive Care Authors: Pierre-Grégoire GuinotEugénie BernardMélanie LevrardHervé DupontEmmanuel Lorne Source Type: research
Myocardial dysfunction in severe sepsis and septic shock - no correlation with inflammatory cytokines in real-life clinical setting.
Conclusions: Unlike cardiac biomarkers, none of the measured inflammatory cytokines correlates with systolic or diastolic myocardial dysfunction in severe sepsis or septic shock.
PMID: 25591166 [PubMed - as supplied by publisher]
Source: Chest - January 15, 2015 Category: Respiratory Medicine Authors: Landesberg G, Levin PD, Gilon D, Goodman S, Georgieva M, Weissman C, Jaffe AS, Sprung CL, Barak V Tags: Chest Source Type: research
FloTrac® Monitoring System: What Are Its Uses in Critically Ill Medical Patients?
Abstract
: The FloTrac®/Vigileo device uses arterial pressure waveform analysis to calculate stroke volume and cardiac output; it does not require calibration against an independent measurement of cardiac output. Consequently, it provides a method to determine hemodynamic status, changes in the clinical course and responses to therapeutic interventions in patients who have arterial catheters in place. These devices perform relatively well in stable patients undergoing surgery and having an acceptable percentage error in differences between the FloTrac® device and invasive monitoring using pulmonary catheters. Ho...
Source: The American Journal of the Medical Sciences - January 12, 2015 Category: Journals (General) Authors: Argueta E, Berdine G, Pena C, Nugent KM Tags: Am J Med Sci Source Type: research
Single induction dose of etomidate versus other induction agents for endotracheal intubation in critically ill patients.
CONCLUSIONS: Although we have not found conclusive evidence that etomidate increases mortality or healthcare resource utilization in critically ill patients, it does seem to increase the risk of adrenal gland dysfunction and multi-organ system dysfunction by a small amount. The clinical significance of this finding is unknown. This evidence is judged to be of moderate quality, owing mainly to significant attrition bias in some of the smaller studies, and new research may influence the outcomes of our review. The applicability of these data may be limited by the fact that 42% of the patients in our review were intubated for...
Source: Cochrane Database of Systematic Reviews - January 8, 2015 Category: Journals (General) Authors: Bruder EA, Ball IM, Ridi S, Pickett W, Hohl C Tags: Cochrane Database Syst Rev Source Type: research
Sepsis, Septic Shock, and Fatal Exertional Heat Stroke
Exertional heat stroke (EHS) is a clinical syndrome of hyperthermia, encephalopathy, and multiorgan dysfunction that can be irreversible and fatal. While prompt recognition and immediate, aggressive total body cooling can prevent progression of the clinical syndrome, even a short delay can exacerbate the effects of hyperthermia-induced changes. EHS is linked to an inflammatory response that is akin to the systemic inflammatory response syndrome (SIRS). However because EHS is not a common problem in most hospital intensive care units and is not in the usual list of SIRS causes, it may be overlooked easily. Furthermore norma...
Source: Current Sports Medicine Reports - January 1, 2015 Category: Sports Medicine Tags: General Medical Conditions: Section Articles Source Type: research
Sepsis, septic shock, and fatal exertional heat stroke.
Abstract
Exertional heat stroke (EHS) is a clinical syndrome of hyperthermia, encephalopathy, and multiorgan dysfunction that can be irreversible and fatal. While prompt recognition and immediate, aggressive total body cooling can prevent progression of the clinical syndrome, even a short delay can exacerbate the effects of hyperthermia-induced changes. EHS is linked to an inflammatory response that is akin to the systemic inflammatory response syndrome (SIRS). However because EHS is not a common problem in most hospital intensive care units and is not in the usual list of SIRS causes, it may be overlooked easily....
Source: Current Sports Medicine Reports - January 1, 2015 Category: Sports Medicine Authors: Epstein Y, Roberts WO, Golan R, Heled Y, Sorkine P, Halpern P Tags: Curr Sports Med Rep Source Type: research
Optimization of preload in severe sepsis and septic shock.
Authors: Shujaat A, Bajwa AA
Abstract
In sepsis both under- and overresuscitation are associated with increased morbidity and mortality. Moreover, sepsis can be complicated by myocardial dysfunction, and only half of the critically ill patients exhibit preload responsiveness. It is of paramount importance to accurately, safely, and rapidly determine and optimize preload during resuscitation. Traditional methods of determining preload based on measurement of pressure in a heart chamber or volume of a heart chamber ("static" parameters) are inaccurate and should be abandoned in favor of determining preload responsive...
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research
Risk factors for venous thromboembolism in patients undergoing craniotomy for neoplastic disease
Abstract
Patients undergoing neurosurgical procedures for neoplasia have historically been considered at higher risk for developing venous thromboembolism (VTE). We sought to identify risk factors associated with VTE in patients undergoing craniotomy for tumor resection. We reviewed a national surgical quality database (American College of Surgeons National Surgical Quality Improvement Project, ACS-NSQIP, http://site.acsnsqip.org/). Patients undergoing non-emergent craniotomy for neoplastic indications were identified based on current procedural terminology codes. Clinical factors were identified that were associ...
Source: Journal of Neuro-Oncology - November 19, 2014 Category: Cancer & Oncology Source Type: research
Optimizing Oxygen Delivery in the Critically Ill: Assessment of Volume Responsiveness in the Septic Patient
Assessing volume responsiveness, defined as an increase in cardiac index after infusion of fluids, is important when caring for critically ill patients in septic shock, as both under- and over-resuscitation can worsen outcomes. This review article describes the currently available methods of assessing volume responsiveness for critically ill patients in the emergency department, with a focus on patients in septic shock.The single-pump model of the circulation utilizing cardiac-filling pressures is reviewed in detail. Additionally, the dual-pump model evaluating cardiopulmonary interactions both invasively and noninvasively...
Source: The Journal of Emergency Medicine - July 31, 2014 Category: Emergency Medicine Authors: Benjamin de Witt, Raj Joshi, Harvey Meislin, Jarrod M. Mosier Source Type: research
Arginine infusion in septic shock patients increases nitric oxide production without hemodynamic instability
In conclusion, a4-fold increase of plasma arginine with intravenous arginine infusion in sepsis stimulates de novo arginine and NO production and reduces whole body protein breakdown. These potential beneficial metabolic effects occurred without negative alterations in hemodynamic parameters, although improvement of regional perfusion could not be demonstrated in the eight patients with septic shock that were studied.
Source: Clinical Science - July 18, 2014 Category: Biomedical Science Authors: Y C Luiking, M Poeze, N EP Deutz Source Type: research
CardioPulse Articles * Warfarin increases stroke risk in atrial fibrillation * Aspirin still overprescribed for stroke prevention in atrial fibrillation * Clinical Research in Cardiology: the official journal of the German Cardiac Society (Deutsche Gesellschaft fur Herz-/Kreislaufforschung) * Septic shock in infective endocarditis * Innovation in atrial fibrillation therapy
Source: European Heart Journal - June 7, 2014 Category: Cardiology Tags: CardioPulse Source Type: research
Ventriculo-arterial decoupling in human septic shock
Conclusions:
On admission to ICU patients in septic shock often display significant ventriculo-arterial decoupling that is associated with impaired left ventricular performance. Since Ea/Ees decoupling alters cardiovascular efficiency and cardiac energetic requirements independent of Ea or Ees, we speculate that uncoupled septic patients may benefit from therapy aimed at normalizing Ea/Ees.
Source: Critical Care - April 24, 2014 Category: Intensive Care Authors: Fabio GuarracinoBaldassarre FerroAndrea MorelliPietro BertiniRubia BaldassarriMichael Pinsky Source Type: research
