Hospital-Acquired Blood Stream Infection in an Adult Intensive Care Unit
CONCLUSION: Critical-care patients are at risk of secondary bloodstream infection. This study highlights the importance of measures to reduce the risk of infection in the intensive-care setting, particularly in patients who have undergone invasive procedures.PMID:34285815 | PMC:PMC8275436 | DOI:10.1155/2021/3652130 (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - July 21, 2021 Category: Intensive Care Authors: Jeffrey Harte Germander Soothill John Glynn David Samuel Laurence Sharifi Mary White Source Type: research

Validation of the Acute Physiology and Chronic Health Evaluation (APACHE) II and IV Score in COVID-19 Patients
CONCLUSIONS: APACHE IV provided the best discrimination and calibration of the considered scoring systems in critically ill COVID-19 patients, both in the overall group and in the subgroup with anti-Xa adjusted LMWH doses. Only in the subgroup analysis, discriminative abilities of APACHE IV were very good. This trial is registered with NCT04713852.PMID:34258059 | PMC:PMC8225448 | DOI:10.1155/2021/5443083 (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - July 14, 2021 Category: Intensive Care Authors: Jeroen Vandenbrande Laurens Verbrugge Liesbeth Bruckers Laurien Geebelen Ester Geerts Ina Callebaut Ine Gruyters Liesbeth Heremans Jasperina Dubois Bjorn Stessel Source Type: research

Corrigendum to "Clinical Outcomes of Critically Ill Patients Using Inhaled Nitric Oxide (iNO) during Intrahospital Transport"
Crit Care Res Pract. 2021 Jun 16;2021:9794018. doi: 10.1155/2021/9794018. eCollection 2021.ABSTRACT[This corrects the article DOI: 10.1155/2021/6633210.].PMID:34249376 | PMC:PMC8238561 | DOI:10.1155/2021/9794018 (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - July 12, 2021 Category: Intensive Care Authors: Leonid Koyfman Omri Simchon Anna Koyfman Shoshana Moshinsky Benjamin Fredrick Gruenbaum Ron Gal Michael Friger Natan Arotsker Alexander Zlotnik Moti Klein Evgeni Brotfain Source Type: research

Postintubation Decline in Oxygen Saturation Index Predicts Mortality in COVID-19: A Retrospective Pilot Study
Crit Care Res Pract. 2021 May 26;2021:6682944. doi: 10.1155/2021/6682944. eCollection 2021.ABSTRACTBACKGROUND: Acute respiratory failure from COVID-19 pneumonia is a major cause of death after SARS-CoV-2 infection. We investigated whether PaO2/FiO2, oxygenation index (OI), SpO2/FiO2, and oxygen saturation index (OSI), commonly used to assess the severity of acute respiratory distress syndrome (ARDS), can predict mortality in mechanically ventilated COVID-19 patients.METHODS: In this single-centered retrospective pilot study, we enrolled 68 critically ill mechanically ventilated adult patients with confirmed COVID-19. Physi...
Source: Critical Care Research and Practice - June 17, 2021 Category: Intensive Care Authors: Ala Nozari Shivali Mukerji Molly Vora Alfonso Garcia Alyssa Park Nicholas Flores Robert Canelli Gerardo Rodriguez Riccardo Pinciroli Alexander Nagrebetsky Rafael Ortega Sadeq A Quraishi Source Type: research

Knowledge, Attitude, and Practice of Nurses Working in the Adult Intensive-Care Unit and Associated Factors towards the Use of Physical Restraint in Federally Administered Hospitals in Addis Ababa, Ethiopia: A Multicenter Cross-Sectional Study
CONCLUSION: According to the study, there was a poor level of nurses' knowledge, proper attitude, and satisfactory practice toward the use of physical restraints.PMID:34123421 | PMC:PMC8169276 | DOI:10.1155/2021/5585140 (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - June 14, 2021 Category: Intensive Care Authors: Lielt Mersha Woldekirkos Tilahun Jiru Heyria Hussien Belayneh Shetie Source Type: research

Predicting Poor Outcome of COVID-19 Patients on the Day of Admission with the COVID-19 Score
CONCLUSIONS: Our study demonstrated that poor outcome in COVID-19 patients can be predicted with good sensitivity and specificity using a few laboratory tests. This is useful for identifying patients at risk during admission.PMID:34123422 | PMC:PMC8189812 | DOI:10.1155/2021/5585291 (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - June 14, 2021 Category: Intensive Care Authors: Luke Tseng Erin Hittesdorf Mitchell F Berman Desmond A Jordan Nina Yoh Katerina Elisman Katherine A Eiseman Yuqi Miao Shuang Wang Gebhard Wagener Source Type: research

Knowledge, Attitude, and Practice of Nurses Working in the Adult Intensive-Care Unit and Associated Factors towards the Use of Physical Restraint in Federally Administered Hospitals in Addis Ababa, Ethiopia: A Multicenter Cross-Sectional Study
CONCLUSION: According to the study, there was a poor level of nurses' knowledge, proper attitude, and satisfactory practice toward the use of physical restraints.PMID:34123421 | PMC:PMC8169276 | DOI:10.1155/2021/5585140 (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - June 14, 2021 Category: Intensive Care Authors: Lielt Mersha Woldekirkos Tilahun Jiru Heyria Hussien Belayneh Shetie Source Type: research

Predicting Poor Outcome of COVID-19 Patients on the Day of Admission with the COVID-19 Score
CONCLUSIONS: Our study demonstrated that poor outcome in COVID-19 patients can be predicted with good sensitivity and specificity using a few laboratory tests. This is useful for identifying patients at risk during admission.PMID:34123422 | PMC:PMC8189812 | DOI:10.1155/2021/5585291 (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - June 14, 2021 Category: Intensive Care Authors: Luke Tseng Erin Hittesdorf Mitchell F Berman Desmond A Jordan Nina Yoh Katerina Elisman Katherine A Eiseman Yuqi Miao Shuang Wang Gebhard Wagener Source Type: research

Knowledge, Attitude, and Practice of Nurses Working in the Adult Intensive-Care Unit and Associated Factors towards the Use of Physical Restraint in Federally Administered Hospitals in Addis Ababa, Ethiopia: A Multicenter Cross-Sectional Study
CONCLUSION: According to the study, there was a poor level of nurses' knowledge, proper attitude, and satisfactory practice toward the use of physical restraints.PMID:34123421 | PMC:PMC8169276 | DOI:10.1155/2021/5585140 (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - June 14, 2021 Category: Intensive Care Authors: Lielt Mersha Woldekirkos Tilahun Jiru Heyria Hussien Belayneh Shetie Source Type: research

Predicting Poor Outcome of COVID-19 Patients on the Day of Admission with the COVID-19 Score
CONCLUSIONS: Our study demonstrated that poor outcome in COVID-19 patients can be predicted with good sensitivity and specificity using a few laboratory tests. This is useful for identifying patients at risk during admission.PMID:34123422 | PMC:PMC8189812 | DOI:10.1155/2021/5585291 (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - June 14, 2021 Category: Intensive Care Authors: Luke Tseng Erin Hittesdorf Mitchell F Berman Desmond A Jordan Nina Yoh Katerina Elisman Katherine A Eiseman Yuqi Miao Shuang Wang Gebhard Wagener Source Type: research

The Relationship between Experienced Respiratory Symptoms and Health-Related Quality of Life in the Elderly with Chronic Obstructive Pulmonary Disease
This study aimed to investigate HRQoL in elderly patients with COPD and examine the relationship between this in relation to respiratory symptoms experienced by them and their demographic characteristics.METHODS: This is a descriptive, correlational study of elderly patients with COPD who were hospitalized in five different hospitals in an urban area of Iran. A consecutive sampling method was used. Demographic data form, the respiratory symptoms component of St. George's Respiratory Questionnaire (SGRQ), and the Short Form 36 Health Survey Questionnaire (SF-36) were applied for data collection.RESULTS: The patients (n = 21...
Source: Critical Care Research and Practice - June 7, 2021 Category: Intensive Care Authors: Daryadokht Masror-Roudsary Nasrin Fadaee Aghdam Forough Rafii Robabe Baha Mahboobeh Khajeh Abbas Mardani Source Type: research

The Performance of Equations That Estimate Glomerular Filtration Rate against Measured Urinary Creatinine Clearance in Critically Ill Patients
Crit Care Res Pract. 2021 May 18;2021:5520653. doi: 10.1155/2021/5520653. eCollection 2021.ABSTRACTThe performance of glomerular filtration rate- (GFR-) estimating equations was studied against creatinine clearance measured by 24-hour urine collection (CrCl24h-urine) in critically ill patients. Methods. In this substudy of the PermiT trial (https://clinicaltrials.gov/ct2/show/ISRCTN68144998), patients from King Abdulaziz Medical City-Riyadh who had CrCl24h-urine were included. We estimated GFR using Cockroft-Gault (CG), modification of diet in renal disease study (MDRD), chronic kidney disease epidemiology collaboration (C...
Source: Critical Care Research and Practice - May 31, 2021 Category: Intensive Care Authors: Hasan M Al-Dorzi Abdulmajeed A Alsadhan Ayman S Almozaini Ali M Alamri Hani Tamim Musharraf Sadat Lolowa Al-Swaidan Elwaleed Elhassan Yaseen M Arabi Source Type: research

Monitoring Unfractionated Heparin in Adult Patients Undergoing Extracorporeal Membrane Oxygenation (ECMO): ACT, APTT, or ANTI-XA?
Crit Care Res Pract. 2021 May 3;2021:5579936. doi: 10.1155/2021/5579936. eCollection 2021.ABSTRACTBACKGROUND: During ECMO, anticoagulants, in particular, unfractionated heparin (UFH), are commonly used and monitored by laboratory tests, including ACT, APTT, and anti-Xa level.METHOD: A single-center retrospective observational study was conducted on adult patients undergoing ECMO between January 2019 and January 2020 at a tertiary hospital. The correlations between ACT, APTT, anti-Xa, antithrombin, and UFH dose were assessed.RESULTS: 129 sets of measurements from 37 patients were obtained including ACT, APTT, anti-Xa, antit...
Source: Critical Care Research and Practice - May 31, 2021 Category: Intensive Care Authors: Tung Phi Nguyen Xuan Thi Phan Dai Quang Huynh Ha Thi Viet Truong Yen Nguyen Hai Le Tuan Manh Nguyen Quan Quoc Minh Du Thao Phuong Le Hai Ngoc Truong Thi Thi Ho Thao Thi Ngoc Pham Source Type: research

Impact of Adjuvant Use of Midodrine to Intravenous Vasopressors: A Systematic Review and Meta-Analysis
CONCLUSION: This meta-analysis suggests that midodrine was not associated with a significant decrease in ICU LOS, hospital LOS, mortality, or ICU readmissions.PMID:34055408 | PMC:PMC8147551 | DOI:10.1155/2021/5588483 (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - May 31, 2021 Category: Intensive Care Authors: Ahmad Al-Abdouh Sadam Haddadin Atul Matta Ahmad Jabri Mahmoud Barbarawi Waiel Abusnina Qais Radideh Mohammed Mhanna Dante A Suffredini Erin D Michos Source Type: research

The Performance of Equations That Estimate Glomerular Filtration Rate against Measured Urinary Creatinine Clearance in Critically Ill Patients
Crit Care Res Pract. 2021 May 18;2021:5520653. doi: 10.1155/2021/5520653. eCollection 2021.ABSTRACTThe performance of glomerular filtration rate- (GFR-) estimating equations was studied against creatinine clearance measured by 24-hour urine collection (CrCl24h-urine) in critically ill patients. Methods. In this substudy of the PermiT trial (https://clinicaltrials.gov/ct2/show/ISRCTN68144998), patients from King Abdulaziz Medical City-Riyadh who had CrCl24h-urine were included. We estimated GFR using Cockroft-Gault (CG), modification of diet in renal disease study (MDRD), chronic kidney disease epidemiology collaboration (C...
Source: Critical Care Research and Practice - May 31, 2021 Category: Intensive Care Authors: Hasan M Al-Dorzi Abdulmajeed A Alsadhan Ayman S Almozaini Ali M Alamri Hani Tamim Musharraf Sadat Lolowa Al-Swaidan Elwaleed Elhassan Yaseen M Arabi Source Type: research

Monitoring Unfractionated Heparin in Adult Patients Undergoing Extracorporeal Membrane Oxygenation (ECMO): ACT, APTT, or ANTI-XA?
Crit Care Res Pract. 2021 May 3;2021:5579936. doi: 10.1155/2021/5579936. eCollection 2021.ABSTRACTBACKGROUND: During ECMO, anticoagulants, in particular, unfractionated heparin (UFH), are commonly used and monitored by laboratory tests, including ACT, APTT, and anti-Xa level.METHOD: A single-center retrospective observational study was conducted on adult patients undergoing ECMO between January 2019 and January 2020 at a tertiary hospital. The correlations between ACT, APTT, anti-Xa, antithrombin, and UFH dose were assessed.RESULTS: 129 sets of measurements from 37 patients were obtained including ACT, APTT, anti-Xa, antit...
Source: Critical Care Research and Practice - May 31, 2021 Category: Intensive Care Authors: Tung Phi Nguyen Xuan Thi Phan Dai Quang Huynh Ha Thi Viet Truong Yen Nguyen Hai Le Tuan Manh Nguyen Quan Quoc Minh Du Thao Phuong Le Hai Ngoc Truong Thi Thi Ho Thao Thi Ngoc Pham Source Type: research

Impact of Adjuvant Use of Midodrine to Intravenous Vasopressors: A Systematic Review and Meta-Analysis
CONCLUSION: This meta-analysis suggests that midodrine was not associated with a significant decrease in ICU LOS, hospital LOS, mortality, or ICU readmissions.PMID:34055408 | PMC:PMC8147551 | DOI:10.1155/2021/5588483 (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - May 31, 2021 Category: Intensive Care Authors: Ahmad Al-Abdouh Sadam Haddadin Atul Matta Ahmad Jabri Mahmoud Barbarawi Waiel Abusnina Qais Radideh Mohammed Mhanna Dante A Suffredini Erin D Michos Source Type: research

The Performance of Equations That Estimate Glomerular Filtration Rate against Measured Urinary Creatinine Clearance in Critically Ill Patients
Crit Care Res Pract. 2021 May 18;2021:5520653. doi: 10.1155/2021/5520653. eCollection 2021.ABSTRACTThe performance of glomerular filtration rate- (GFR-) estimating equations was studied against creatinine clearance measured by 24-hour urine collection (CrCl24h-urine) in critically ill patients. Methods. In this substudy of the PermiT trial (https://clinicaltrials.gov/ct2/show/ISRCTN68144998), patients from King Abdulaziz Medical City-Riyadh who had CrCl24h-urine were included. We estimated GFR using Cockroft-Gault (CG), modification of diet in renal disease study (MDRD), chronic kidney disease epidemiology collaboration (C...
Source: Critical Care Research and Practice - May 31, 2021 Category: Intensive Care Authors: Hasan M Al-Dorzi Abdulmajeed A Alsadhan Ayman S Almozaini Ali M Alamri Hani Tamim Musharraf Sadat Lolowa Al-Swaidan Elwaleed Elhassan Yaseen M Arabi Source Type: research

Monitoring Unfractionated Heparin in Adult Patients Undergoing Extracorporeal Membrane Oxygenation (ECMO): ACT, APTT, or ANTI-XA?
Crit Care Res Pract. 2021 May 3;2021:5579936. doi: 10.1155/2021/5579936. eCollection 2021.ABSTRACTBACKGROUND: During ECMO, anticoagulants, in particular, unfractionated heparin (UFH), are commonly used and monitored by laboratory tests, including ACT, APTT, and anti-Xa level.METHOD: A single-center retrospective observational study was conducted on adult patients undergoing ECMO between January 2019 and January 2020 at a tertiary hospital. The correlations between ACT, APTT, anti-Xa, antithrombin, and UFH dose were assessed.RESULTS: 129 sets of measurements from 37 patients were obtained including ACT, APTT, anti-Xa, antit...
Source: Critical Care Research and Practice - May 31, 2021 Category: Intensive Care Authors: Tung Phi Nguyen Xuan Thi Phan Dai Quang Huynh Ha Thi Viet Truong Yen Nguyen Hai Le Tuan Manh Nguyen Quan Quoc Minh Du Thao Phuong Le Hai Ngoc Truong Thi Thi Ho Thao Thi Ngoc Pham Source Type: research