Impact of a 2-Day Critical Care Ultrasound Course during Fellowship Training: A Pilot Study.
Conclusions. Implementation of a 2-day critical care ultrasound course covering general CCUS and basic critical care echocardiography using a combination of didactics, live models, and ultrasound simulators is effective in improving critical care fellows' proficiency and confidence with ultrasound use in both the short- and long-term settings. PMID: 26346694 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - September 10, 2015 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Lung Injury Prediction Score Is Useful in Predicting Acute Respiratory Distress Syndrome and Mortality in Surgical Critical Care Patients.
This study analyzes the value of LIPS in predicting ARDS and mortality among ventilated surgical patients. Methods. IRB approved, prospective observational study including all ventilated patients admitted to the surgical intensive care unit at a single tertiary center over 6 months. ARDS was defined using the Berlin criteria. LIPS were calculated for all patients and analyzed. Logistic regression models evaluated the ability of LIPS to predict development of ARDS and mortality. A receiver operator characteristic (ROC) curve demonstrated the optimal LIPS value to statistically predict development of ARDS. Results. 268 venti...
Source: Critical Care Research and Practice - August 25, 2015 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

The Use of Sodium Bicarbonate in the Treatment of Acidosis in Sepsis: A Literature Update on a Long Term Debate.
Conclusions. Routine use of bicarbonate for treatment of severe acidemia and lactic acidosis due to sepsis is subject of controversy, and current opinion does not favor routine use of bicarbonates. However, available evidence is inconclusive, and more studies are required to determine the potential benefit, if any, of bicarbonate therapy in the sepsis patient with acidosis. PMID: 26294968 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - August 22, 2015 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Impact of a Simulation-Based Communication Workshop on Resident Preparedness for End-of-Life Communication in the Intensive Care Unit.
This study evaluated a simulation-based intervention designed to improve resident EOL communication skills with families in the ICU. Methods. Thirty-four second-year internal medicine residents at a large urban teaching hospital participated in small group sessions with faculty trained in the "VitalTalk" method. A Likert-type scale questionnaire measured self-assessed preparedness before, immediately following, and approximately 9 months after intervention. Data were analyzed using Wilcoxon rank-sum analysis. Results. Self-assessed preparedness significantly improved for all categories surveyed (preintervention m...
Source: Critical Care Research and Practice - July 24, 2015 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Pressure Measurement Techniques for Abdominal Hypertension: Conclusions from an Experimental Model.
Conclusions from an Experimental Model. Crit Care Res Pract. 2015;2015:278139 Authors: Chopra SS, Wolf S, Rohde V, Freimann FB Abstract Introduction. Intra-abdominal pressure (IAP) measurement is an indispensable tool for the diagnosis of abdominal hypertension. Different techniques have been described in the literature and applied in the clinical setting. Methods. A porcine model was created to simulate an abdominal compartment syndrome ranging from baseline IAP to 30 mmHg. Three different measurement techniques were applied, comprising telemetric piezoresistive probes at two different sites (e...
Source: Critical Care Research and Practice - June 27, 2015 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Propofol infusion syndrome in adults: a clinical update.
Authors: Mirrakhimov AE, Voore P, Halytskyy O, Khan M, Ali AM Abstract Propofol infusion syndrome is a rare but extremely dangerous complication of propofol administration. Certain risk factors for the development of propofol infusion syndrome are described, such as appropriate propofol doses and durations of administration, carbohydrate depletion, severe illness, and concomitant administration of catecholamines and glucocorticosteroids. The pathophysiology of this condition includes impairment of mitochondrial beta-oxidation of fatty acids, disruption of the electron transport chain, and blockage of beta-adrenorec...
Source: Critical Care Research and Practice - May 9, 2015 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Comment on "management of atrial fibrillation in critically ill patients".
Comment on "management of atrial fibrillation in critically ill patients". Crit Care Res Pract. 2015;2015:732598 Authors: Champion S PMID: 25954514 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - May 9, 2015 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Incidence and Risk Factors for Delirium among Mechanically Ventilated Patients in an African Intensive Care Setting: An Observational Multicenter Study.
Authors: Kwizera A, Nakibuuka J, Ssemogerere L, Sendikadiwa C, Obua D, Kizito S, Tumukunde J, Wabule A, Nakasujja N Abstract Aim. Delirium is common among mechanically ventilated patients in the intensive care unit (ICU). There are little data regarding delirium among mechanically ventilated patients in Africa. We sought to determine the burden of delirium and associated factors in Uganda. Methods. We conducted a multicenter prospective study among mechanically ventilated patients in Uganda. Eligible patients were screened daily for delirium using the confusional assessment method (CAM-ICU). Comparisons were made u...
Source: Critical Care Research and Practice - May 7, 2015 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Is There Any Association between PEEP and Upper Extremity DVT?
Authors: Al-Saffar F, Gupta E, Siddiqi F, Faisal M, Jones LM, Seeram V, Louis M, Cury JD, Bajwa AA, Shujaat A Abstract Background. We hypothesized that positive end-exploratory pressure (PEEP) may promote venous stasis in the upper extremities and predispose to upper extremity deep vein thrombosis (UEDVT). Methods. We performed a retrospective case control study of medical intensive care unit patients who required mechanical ventilation (MV) for>72 hours and underwent duplex ultrasound of their upper veins for suspected DVT between January 2011 and December 2013. Results. UEDVT was found in 32 (28.5%) of 112 pat...
Source: Critical Care Research and Practice - May 1, 2015 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Contemporary trends of the epidemiology, clinical characteristics, and resource utilization of necrotizing fasciitis in Texas: a population-based cohort study.
Authors: Oud L, Watkins P Abstract Introduction. There are limited population-level reports on the contemporary trends of the epidemiology, clinical features, resource utilization, and outcomes of necrotizing fasciitis (NF). Methods. We conducted a cohort study of Texas inpatient population, identifying hospitalizations with a diagnosis of NF during the years 2001-2010. The incidence, clinical features, resource utilization, and outcomes of NF hospitalizations were examined. Results. There were 12,172 NF hospitalizations during study period, with ICU admission in 50.3%. The incidence of NF rose 2.7%/year (P = 0.000...
Source: Critical Care Research and Practice - April 23, 2015 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Mucolytics for intubated asthmatic children: a national survey of United kingdom paediatric intensive care consultants.
Conclusion. Significant variation exists regarding the necessity for mucolytics, choice of agent, optimal route, and dose in intubated asthmatic children. PMID: 25722885 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - February 28, 2015 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Postoperative pulmonary dysfunction and mechanical ventilation in cardiac surgery.
Authors: Badenes R, Lozano A, Belda FJ Abstract Postoperative pulmonary dysfunction (PPD) is a frequent and significant complication after cardiac surgery. It contributes to morbidity and mortality and increases hospitalization stay and its associated costs. Its pathogenesis is not clear but it seems to be related to the development of a systemic inflammatory response with a subsequent pulmonary inflammation. Many factors have been described to contribute to this inflammatory response, including surgical procedure with sternotomy incision, effects of general anesthesia, topical cooling, and extracorporeal circulati...
Source: Critical Care Research and Practice - February 25, 2015 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Early Use of the NMDA Receptor Antagonist Ketamine in Refractory and Superrefractory Status Epilepticus.
Authors: Zeiler FA Abstract Refractory status epilepticus (RSE) and superrefractory status epilepticus (SRSE) pose a difficult clinical challenge. Multiple cerebral receptor and transporter changes occur with prolonged status epilepticus leading to pharmacoresistance patterns unfavorable for conventional antiepileptics. In particular, n-methyl-d-aspartate (NMDA) receptor upregulation leads to glutamate mediated excitotoxicity. Targeting these NMDA receptors may provide a novel approach to otherwise refractory seizures. Ketamine has been utilized in RSE. Recent systematic review indicates 56.5% and 63.5% cessation i...
Source: Critical Care Research and Practice - February 6, 2015 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Standardized application of laxatives and physical measures in neurosurgical intensive care patients improves defecation pattern but is not associated with lower intracranial pressure.
Conclusions. The implementation of a SOP for bowel movement increases the frequency of adequate bowel movements in neurosurgical critical care patients. However, this seems not to be associated with reduced ICP values. PMID: 25628896 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - January 30, 2015 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Propofol infusion syndrome: a retrospective analysis at a level 1 trauma center.
Conclusions. Risk factors for PRIS were confirmed as high dose infusions over prolonged periods. Increasing triglyceride levels may serve as reliable biomarkers of impending PRIS, if confirmed in future investigations with larger sample sizes. PMID: 25580289 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - January 14, 2015 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

A Newly Developed Sublingual Tonometric Method for the Evaluation of Tissue Perfusion and Its Validation In Vitro and in Healthy Persons In Vivo and the Results of the Measurements in COPD Patients.
Conclusion. The results of the performed examinations showed that the method is suitable for monitoring the actual condition of the patients by mucosal perfusion tonometry in the sublingual region. PMID: 25580290 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - January 14, 2015 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Heliox Improves Carbon Dioxide Removal during Lung Protective Mechanical Ventilation.
Authors: Beurskens CJ, Brevoord D, Lagrand WK, van den Bergh WM, Vroom MB, Preckel B, Horn J, Juffermans NP Abstract Introduction. Helium is a noble gas with low density and increased carbon dioxide (CO2) diffusion capacity. This allows lower driving pressures in mechanical ventilation and increased CO2 diffusion. We hypothesized that heliox facilitates ventilation in patients during lung-protective mechanical ventilation using low tidal volumes. Methods. This is an observational cohort substudy of a single arm intervention study. Twenty-four ICU patients were included, who were admitted after a cardiac arrest and ...
Source: Critical Care Research and Practice - December 31, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

An in vitro analysis of the effects of intravenous lipid emulsion on free and total local anaesthetic concentrations in human blood and plasma.
Conclusion. In this first in vitro model assessing both free- and total-LA concentrations exposed to ILE in human blood/plasma, ILE effect was linearly correlated with increasing lipophilicity for all but ropivacaine. PMID: 25538850 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 30, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Gram-negative infections in adult intensive care units of latin america and the Caribbean.
Authors: Luna CM, Rodriguez-Noriega E, Bavestrello L, Guzmán-Blanco M Abstract This review summarizes recent epidemiology of Gram-negative infections in selected countries from Latin American and Caribbean adult intensive care units (ICUs). A systematic search of the biomedical literature (PubMed) was performed to identify articles published over the last decade. Where appropriate, data also were collected from the reference list of published articles, health departments of specific countries, and registries. Independent cohort data from all countries (Argentina, Brazil, Chile, Colombia, Cuba, Mexico, Trinid...
Source: Critical Care Research and Practice - December 20, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

A Multidisciplinary Approach to Unplanned Conversion from Off-Pump to On-Pump Beating Heart Coronary Artery Revascularization in Patients with Compromised Left Ventricular Function.
Authors: Tsaousi G, Pitsis AA, Ioannidis GD, Vasilakos DG Abstract Aim. To comparably assess the perioperative risk factors that differentiate off-pump coronary artery bypass (OPCAB) grafting cases from those sustaining unplanned conversion to on-pump beating heart (ONCAB/BH) approach, in patients with left ventricular ejection fraction (LVEF)
Source: Critical Care Research and Practice - December 7, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Model Point-of-Care Ultrasound Curriculum in an Intensive Care Unit Fellowship Program and Its Impact on Patient Management.
Conclusions. Implementation of POC ultrasound in the ICU with a structured fellowship curriculum was associated with an increase in new diagnosis in about 2/3 and change in management in over 1/3 of ICU patients studied. PMID: 25478217 [PubMed - as supplied by publisher] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 7, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Pulmonary Artery Catheter (PAC) Accuracy and Efficacy Compared with Flow Probe and Transcutaneous Doppler (USCOM): An Ovine Cardiac Output Validation.
Conclusions. PAC demonstrated poor accuracy and sensitivity as a measure of CO. USCOM provided equivalent measurements to FP across a sixfold range of outputs, reliably detecting ±5% changes. PMID: 22649718 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Sonographic and clinical features of upper extremity deep venous thrombosis in critical care patients.
Conclusion. Presence of CVC was a strong predictor for the development of UEDVT in a cohort of critical care patients; however, the rate of subsequent PE and related mortality was low. PMID: 22655181 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Study Design of the Microcirculatory Shock Occurrence in Acutely Ill Patients (microSOAP): an International Multicenter Observational Study of Sublingual Microcirculatory Alterations in Intensive Care Patients.
Conclusion. This study will be the largest microcirculation study ever performed. It is expected that this study will also establish a basis for future studies related to the microcirculation in critically ill. PMID: 22666566 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

High-flow nasal interface improves oxygenation in patients undergoing bronchoscopy.
Authors: Lucangelo U, Vassallo FG, Marras E, Ferluga M, Beziza E, Comuzzi L, Berlot G, Zin WA Abstract During bronchoscopy hypoxemia is commonly found and oxygen supply can be delivered by interfaces fed with high gas flows. Recently, the high-flow nasal cannula (HFNC) has been introduced for oxygen therapy in adults, but they have not been used so far during bronchoscopy in adults. Forty-five patients were randomly assigned to 3 groups receiving oxygen: 40 L/min through a Venturi mask (V40, N = 15), nasal cannula (N40, N = 15), and 60 L/min through a nasal cannula (N60, N = 15) during bronchoscopy. G...
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

The end-organ impairment in liver cirrhosis: appointments for critical care.
Authors: Figueiredo A, Romero-Bermejo F, Perdigoto R, Marcelino P Abstract Liver cirrhosis (LC) can lead to a clinical state of liver failure, which can exacerbate through the course of the disease. New therapies aimed to control the diverse etiologies are now more effective, although the disease may result in advanced stages of liver failure, where liver transplantation (LT) remains the most effective treatment. The extended lifespan of these patients and the extended possibilities of liver support devices make their admission to an intensive care unit (ICU) more probable. In this paper the LC is approached from t...
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Variability in Uremic Control during Continuous Venovenous Hemodiafiltration in Trauma Patients.
Conclusions. TP undergoing CRRT had short daily CRRT duration causing reduced uremic control. Clinicians should modify their daily clinical practice to improve technical skills and achieve sufficient dialysis dose. PMID: 22666569 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Left ventricular diastolic dysfunction in the intensive care unit: trends and perspectives.
Authors: Eisen LA, Davlouros P, Karakitsos D Abstract Heart failure with a normal or nearly normal left ventricular (LV) ejection fraction (HFNEF) may represent more than 50% of heart failure cases. Although HFNEF is being increasingly recognized, there is a relative lack of information regarding its incidence and prognostic implications in intensive care unit (ICU) patients. In the ICU, many factors related to patient's history, or applied therapies, may induce or aggravate LV diastolic dysfunction. This may impact on patients' morbidity and mortality. This paper discusses methods for assessing LV diastolic functi...
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Advanced neuromonitoring and imaging in pediatric traumatic brain injury.
Authors: Friess SH, Kilbaugh TJ, Huh JW Abstract While the cornerstone of monitoring following severe pediatric traumatic brain injury is serial neurologic examinations, vital signs, and intracranial pressure monitoring, additional techniques may provide useful insight into early detection of evolving brain injury. This paper provides an overview of recent advances in neuromonitoring, neuroimaging, and biomarker analysis of pediatric patients following traumatic brain injury. PMID: 22675618 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

The Microcirculation Is Unchanged in Neonates with Severe Respiratory Failure after the Initiation of ECMO Treatment.
Authors: Top AP, Buijs EA, Schouwenberg PH, van Dijk M, Tibboel D, Ince C Abstract Purpose. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is known to improve cardiorespiratory function and outcome in neonates with severe respiratory failure. We tested the hypothesis that VA-ECMO therapy improves the microcirculation in neonates with severe respiratory failure. Methods. This single-center prospective observational pilot study took place in an intensive care unit of a level III university children's hospital. Twenty-one-term neonates, who received VA-ECMO treatment, were included. The microcirculation wa...
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Commonly used severity scores are not good predictors of mortality in sepsis from severe leptospirosis: a series of ten patients.
Conclusion. Commonly used severity scores do not seem to be useful in predicting mortality in severe leptospirosis. Early ICU admission and resuscitation based on a goal-directed therapy protocol are recommended and may reduce mortality. However, this study is limited by retrospective data collection and small sample size. Data from large prospective studies are needed to validate our findings. PMID: 22675620 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

An ultrasound study of cerebral venous drainage after internal jugular vein catheterization.
Conclusions. Ultrasound-guided IJV cannulation in neurosurgical patients at risk for intracranial hypertension does not impair significantly jugular venous flow and indirectly cerebral venous return. PMID: 22675621 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Alterations of the Erythrocyte Membrane during Sepsis.
Authors: Serroukh Y, Djebara S, Lelubre C, Zouaoui Boudjeltia K, Biston P, Piagnerelli M Abstract Erythrocytes have been long considered as "dead" cells with transport of oxygen (O(2)) as their only function. However, the ability of red blood cells (RBCs) to modulate the microcirculation is now recognized as an important additional function. This capacity is regulated by a key element in the rheologic process: the RBC membrane. This membrane is a complex unit with multiple interactions between the extracellular and intracellular compartments: blood stream, endothelium, and other blood cells on the one han...
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Mechanical ventilation and the titer of antibodies as risk factors for the development of transfusion-related lung injury.
Conclusions. In the presence of injurious MV, onset of TRALI depends on the titer of antibodies infused. PMID: 22701787 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Microcirculation and macrocirculation in cardiac surgical patients.
Authors: Tripodaki ES, Tasoulis A, Koliopoulou A, Vasileiadis I, Vastardis L, Giannis G, Argiriou M, Charitos C, Nanas S Abstract Background. The aim of our study was to investigate the relationship between microcirculatory alterations after open cardiac surgery, macrohemodynamics, and global indices of organ perfusion. Methods. Patients' microcirculation was assessed with near-infrared spectroscopy (NIRS) and the vascular occlusion technique (VOT). Results. 23 patients undergoing open cardiac surgery (11 male/12 female, median age 68 (range 28-82) years, EuroSCORE 6 (1-12)) were enrolled in the study. For pooled d...
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Abdominal compartment syndrome: risk factors, diagnosis, and current therapy.
Authors: Luckianow GM, Ellis M, Governale D, Kaplan LJ Abstract Abdominal compartment syndrome's manifestations are difficult to definitively detect on physical examination alone. Therefore, objective criteria have been articulated that aid the bedside clinician in detecting intra-abdominal hypertension as well as the abdominal compartment syndrome to initiate prompt and potentially life-saving intervention. At-risk patient populations should be routinely monitored and tiered interventions should be undertaken as a team approach to management. PMID: 22720147 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Intracranial Pressure Monitoring: Invasive versus Non-Invasive Methods-A Review.
Authors: Raboel PH, Bartek J, Andresen M, Bellander BM, Romner B Abstract Monitoring of intracranial pressure (ICP) has been used for decades in the fields of neurosurgery and neurology. There are multiple techniques: invasive as well as noninvasive. This paper aims to provide an overview of the advantages and disadvantages of the most common and well-known methods as well as assess whether noninvasive techniques (transcranial Doppler, tympanic membrane displacement, optic nerve sheath diameter, CT scan/MRI and fundoscopy) can be used as reliable alternatives to the invasive techniques (ventriculostomy and microtra...
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Goal-directed fluid therapy using stroke volume variation does not result in pulmonary fluid overload in thoracic surgery requiring one-lung ventilation.
Conclusions. SVV-guided fluid management in thoracic surgery requiring lateral thoracotomy and one-lung ventilation does not result in pulmonary fluid overload. Although oxygenation was reduced, pulmonary function remained within a clinically acceptable range. PMID: 22778929 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Impact of enzymatic degradation of the endothelial glycocalyx on vascular permeability in an awake hamster model.
Conclusion. Vascular leakage was not confirmed in an in vivo, whole body model after degradation of the endothelial glycocalyx. The microcirculation was affected, but no relationship between plasma levels of HA and FCD was seen. PMID: 22792450 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Comment on "effectiveness of physiotherapy for ventilator-associated pneumonia".
Comment on "effectiveness of physiotherapy for ventilator-associated pneumonia". Crit Care Res Pract. 2012;2012:329843 Authors: Ntoumenopoulos G PMID: 22811896 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Ultrasound applications in critical care medicine.
Authors: Hoppmann R, Karakitsos D PMID: 22844586 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Heat and Moisture Exchangers and Humidification Efficacy in Pediatrics: Effects of Ventilator Settings and ETT Leakage.
Authors: de Klerk A, Esquinas AM PMID: 22900156 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Optimization of preload in severe sepsis and septic shock.
Authors: Shujaat A, Bajwa AA Abstract In sepsis both under- and overresuscitation are associated with increased morbidity and mortality. Moreover, sepsis can be complicated by myocardial dysfunction, and only half of the critically ill patients exhibit preload responsiveness. It is of paramount importance to accurately, safely, and rapidly determine and optimize preload during resuscitation. Traditional methods of determining preload based on measurement of pressure in a heart chamber or volume of a heart chamber ("static" parameters) are inaccurate and should be abandoned in favor of determining preload ...
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Lung Function before and Two Days after Open-Heart Surgery.
Authors: Urell C, Westerdahl E, Hedenström H, Janson C, Emtner M Abstract Reduced lung volumes and atelectasis are common after open-heart surgery, and pronounced restrictive lung volume impairment has been found. The aim of this study was to investigate factors influencing lung volumes on the second postoperative day. Open-heart surgery patients (n = 107, 68 yrs, 80% male) performed spirometry both before surgery and on the second postoperative day. The factors influencing postoperative lung volumes and decrease in lung volumes were investigated with univariate and multivariate analyses. Associations between ...
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Derecruitment test and surfactant therapy in patients with acute lung injury.
Conclusions. Our study demonstrated no predictive value of the derecruitment test regarding the effects of RM. Surfactant instillation was not superior to conventional therapy and might even promote pulmonary edema in ALI. PMID: 22928094 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Respiratory Impairment after Early Red Cell Transfusion in Pediatric Patients with ALI/ARDS.
Authors: Rajasekaran S, Sanfilippo D, Shoemaker A, Curtis S, Zuiderveen S, Ndika A, Stoiko M, Hassan N Abstract Introduction. In the first 48 hours of ventilating patients with acute lung injury (ALI)/acute respiratory distress syndrome (ARDS), a multipronged approach including packed red blood cell (PRBC) transfusion is undertaken to maintain oxygen delivery. Hypothesis. We hypothesized children with ALI/ARDS transfused within 48 hours of initiating mechanical ventilation would have worse outcome. The course of 34 transfused patients was retrospectively compared to 45 nontransfused control patients admitted to the...
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Goal-oriented respiratory management for critically ill patients with acute respiratory distress syndrome.
Authors: Barbas CS, Matos GF, Amato MB, Carvalho CR Abstract This paper, based on relevant literature articles and the authors' clinical experience, presents a goal-oriented respiratory management for critically ill patients with acute respiratory distress syndrome (ARDS) that can help improve clinicians' ability to care for these patients. Early recognition of ARDS modified risk factors and avoidance of aggravating factors during hospital stay such as nonprotective mechanical ventilation, multiple blood products transfusions, positive fluid balance, ventilator-associated pneumonia, and gastric aspiration can help ...
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Monitoring in the intensive care.
Authors: Kipnis E, Ramsingh D, Bhargava M, Dincer E, Cannesson M, Broccard A, Vallet B, Bendjelid K, Thibault R Abstract In critical care, the monitoring is essential to the daily care of ICU patients, as the optimization of patient's hemodynamic, ventilation, temperature, nutrition, and metabolism is the key to improve patients' survival. Indeed, the decisive endpoint is the supply of oxygen to tissues according to their metabolic needs in order to fuel mitochondrial respiration and, therefore, life. In this sense, both oxygenation and perfusion must be monitored in the implementation of any resuscitation strategy...
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Failed weaning from mechanical ventilation and cardiac dysfunction.
Authors: Porhomayon J, Papadakos P, Nader ND Abstract Failure to transition patient from controlled mechanical ventilation to spontaneous breathing trials (SBTs) in a timely fashion is associated with significant morbidity and mortality in the intensive care unit. In addition, weaning failures are common in patients with limited cardiac reserves. Recent advances in cardiac echocardiography and laboratory measurement of serum biomarkers to assess hemodynamic response to SBT may provide additional information to guide clinicians to predict weaning outcome. PMID: 22991658 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Monitoring in the intensive care unit: its past, present, and future.
Authors: Cannesson M, Broccard A, Vallet B, Bendjelid K PMID: 23019523 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 1, 2014 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research