Identification of the Range of Nursing Skills Used to Provide Social Support for Mothers of Preterm Infants in Neonatal Intensive Care.
Conclusion: There were positive associations between social support from nurses and mothers' satisfaction with the care of their infants. Therefore, planning to promote and create opportunities for neonatal nurses to support mothers in NICU is important to promote increased maternal satisfaction in infant care. PMID: 33505719 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - January 30, 2021 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Critical Incident Disclosing Behaviors and Associated Factors among Nurses Working in Amhara Region Referral Hospitals, Northwest Ethiopia: A Cross-Sectional Study.
Authors: Eshete Y, Tesfaye B, Dagnew Z, Kefale D, Mesfin Belay D, Minuye B Abstract Background: Though the goal of healthcare institutions is patient safety, errors have been committed by healthcare providers. Incident reporting behavior enhances patient safety by reducing the repeated occurrence of errors in the health facility. Therefore, this study aims to identify incident disclosing behaviors and associated factors among nurses working in referral hospitals, Northwest Ethiopia. Methods: Institution-based cross-sectional study design was conducted among randomly selected 319 nurses working in referral hospi...
Source: Critical Care Research and Practice - January 30, 2021 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

The Effect of Fluid Overload on Attributable Morbidity after Cardiac Surgery: A Retrospective Study.
Authors: Koc V, Delmas Benito L, de With E, Boerma EC Abstract Introduction: Although the detrimental effects of excessive perioperative fluid administration are generally well established, data in the setting of cardiac surgery remain less robust. Methods: In this retrospective single-center observational study, the total fluid balance in the first 12 hours during and after surgery was evaluated. Primary endpoint was the relationship between total fluid balance and the incidence of prolonged mechanical ventilation. For this purpose, data were divided into quartiles (Q); prolonged mechanical ventilation and pro...
Source: Critical Care Research and Practice - January 27, 2021 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Current Physical Therapy Practice in the Intensive Care Unit in Saudi Arabia: A Multicentre Cross-Sectional Survey.
Conclusion: PTs reported significant variation in the choice of treatment for different clinical cases inside ICU. The main barriers in the ICU setting were low confidence and inadequate training. PMID: 33457013 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - January 20, 2021 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Area under the Curve-Based Dosing of Vancomycin in Critically Ill Patients Using 6-Hour Urine Creatinine Clearance Measurement.
Authors: Shahrami B, Najmeddin F, Ghaffari S, Najafi A, Rouini MR, Mojtahedzadeh M Abstract Background: The area under the curve- (AUC-) guided vancomycin dosing is the best strategy for individualized therapy in critical illnesses. Since AUC can be calculated directly using drug clearance (CLvan), any parameter estimating CLvan will be able to achieve the goal of 24-hour AUC (AUC24 h). The present study was aimed to determine CLvan based on 6-hour urine creatinine clearance measurement in critically ill patients with normal renal function. Method: 23 adult critically ill patients with an estimated glome...
Source: Critical Care Research and Practice - January 13, 2021 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Sleep Promotion among Critically Ill Patients: Earplugs/Eye Mask versus Ocean Sound-A Randomized Controlled Trial Study.
Conclusion: Earplugs and eye mask were better than ocean sound in improving sleep quality. Earplugs, eye mask, and ocean sound are safe and cost effective, which could be used as an adjuvant to pharmacological interventions to improve sleep quality among ICU patients. However, further research in this area needs to be conducted. This trial is registered with NCT03215212. PMID: 33425385 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - January 13, 2021 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Lung Ultrasound and Sonographic Subpleural Consolidation in COVID-19 Pneumonia Correlate with Disease Severity.
Authors: Bitar ZI, Shamsah M, Maadarani O, Bamasood OM, Bitar AZ, Alfoudri H Abstract Introduction: One of the ultrasonic features of COVID-19 pneumonia is the presence of subpleural consolidation (SPC), and the number of SPCs varies among patients with COVID-19 pneumonia. Aim: To examine the relationship between disease severity and the number of SPCs on admission. Methodology. This observational, prospective, single-center study included patients with suspected COVID-19 infection who had been transferred to the ICU. A specialized intensivist in critical care ultrasound performed lung ultrasound (LUS) and echo...
Source: Critical Care Research and Practice - January 13, 2021 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Hemodynamic Characteristics of Mechanically Ventilated COVID-19 Patients: A Cohort Analysis.
Authors: Boerma EC, Bethlehem C, Stellingwerf F, de Lange F, Streng KW, Koetsier PM, Bootsma IT Abstract Background: Solid data on cardiovascular derangements in critically ill COVID-19 patients remain scarce. The aim of this study is to describe hemodynamic characteristics in a cohort of COVID-19-related critically ill patients. Methods: A retrospective observational cohort study in twenty-eight consecutive mechanically ventilated COVID-19 patients. Pulse contour analysis-derived data were obtained from all patients, using the PiCCO® system. Results: The mean arterial pressure increased from 77 ...
Source: Critical Care Research and Practice - January 13, 2021 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Simulation-Based Rapid Development and Implementation of a Novel Barrier Enclosure for Use in COVID-19 Patients: The SplashGuard CG.
Conclusion: The rapid design, development, and clinical implementation of a new barrier enclosure, the "SplashGuard CG," was feasible in this time of crisis thanks to close collaboration between medical and engineering teams and the use of recurring simulation sessions to test and improve the initial prototypes. Following this accelerated process, it is necessary to maintain team skills, monitor any undesirable effects, and evaluate and continuously improve this new device. PMID: 33381311 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - January 1, 2021 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Prone Position after Liberation from Prolonged Mechanical Ventilation in COVID-19 Respiratory Failure.
Conclusions: The novel practice of PEPP after liberation from prolonged mechanical ventilation in patients with COVID-19 respiratory failure is feasible and well tolerated, and may be associated with favourable clinical outcomes including improvement in oxygenation and respiratory rate and a low rate of reintubation. Larger prospective studies of PEPP are warranted. PMID: 33299605 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 12, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Effectiveness, Safety, and Barriers to Early Mobilization in the Intensive Care Unit.
Conclusion: Early mobilization is found to have positive effects on various outcomes in patients with or without mechanical ventilation. The newer techniques can be used to facilitate early mobilization. Scoring systems-specific to the ICU-are available and should be used to quantify patients' status at different intervals of time. Early mobilization is not commonly practiced in many countries. Various barriers to early mobilization have been identified, and different strategies can be used to overcome them. PMID: 33294221 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 11, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Central Venous Catheter Insertion: A Scoring System for Evaluation of Both the Procedure and the Operator (CVCI Score/Gaber Score).
Conclusion: We suggest a new scoring system for CVC insertion that can be used for evaluation of both the technique and the operator. It can evaluate the performance of junior staff and follow their progress. It can be applied in the medical and critical care practice as well as the quality management privileges and protocols. PMID: 33204529 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - November 21, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

The Attitudes of Relatives of ICU Patients toward Informed Consent for Clinical Research.
Conclusion: Relatives with a critically ill next of kin in the ICU had positive attitudes toward providing informed consent on behalf of their patients. This was motivated by the direct benefit from the research to their patient. PMID: 33133692 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - November 4, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Knowledge, Attitude, and Performance of ICU, CCU, and Emergency Wards Nurses in Kermanshah, Iran, regarding Organ Donation.
This study is aimed at investigating the knowledge, attitude, and performance of nurses working in the ICU, CCU, and emergency wards regarding organ donation. Methods: In this descriptive-analytical study, 185 nurses working in ICU, CCU, and emergency wards were studied through systematic random sampling. The data collection was done by a self-administered questionnaire. Results: The mean knowledge of nurses was 8.9 ± 1.4 out of 10. There was a significant relationship between knowledge of nurses regarding donation and religion and having organ donation card (P
Source: Critical Care Research and Practice - October 21, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Dermatological Manifestations in the Intensive Care Unit: A Practical Approach.
Authors: Badia M, Casanova JM, Serviá L, Montserrat N, Codina J, Trujillano J Abstract Dermatological problems are not usually related to intensive medicine because they are considered to have a low impact on the evolution of critical patients. Despite this, dermatological manifestations (DMs) are relatively frequent in critically ill patients. In rare cases, DMs will be the main diagnosis and will require intensive treatment due to acute skin failure. In contrast, DMs can be a reflection of underlying systemic diseases, and their identification may be key to their diagnosis. On other occasions, DMs are lesi...
Source: Critical Care Research and Practice - October 21, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Effect of Exogenous Melatonin Administration in Critically Ill Patients on Delirium and Sleep: A Randomized Controlled Trial.
Conclusion: High levels of plasma melatonin during the overnight period of intensive care cohort patients did not improve sleep nor decreased the prevalence of delirium. This trial is registered with Anzctr.org.au/ACTRN12620000661976.aspx. PMID: 33029397 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - October 9, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Bioreactance-Based Noninvasive Fluid Responsiveness and Cardiac Output Monitoring: A Pilot Study in Patients with Aneurysmal Subarachnoid Hemorrhage and Literature Review.
Authors: Sivakumar S, Lazaridis C Abstract Management of volume status, arterial blood pressure, and cardiac output are core elements in approaching the patients with aneurysmal subarachnoid hemorrhage (SAH). For the prevention and treatment of delayed cerebral ischemia (DCI), euvolemia is advocated and caution is made towards the avoidance of hypervolemia. Induced hypertension and cardiac output augmentation are the mainstays of medical management during active DCI, whereas the older triple-H paradigm has fallen out of favor due to lack of demonstrable physiological or clinical benefits and serious concern for adv...
Source: Critical Care Research and Practice - October 6, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Lactate Arterial-Central Venous Gradient among COVID-19 Patients in ICU: A Potential Tool in the Clinical Practice.
Conclusion: A reversed Delta a-cv lactate might be interpreted as one of the effects of COVID-19-related cytokine storm, which could reflect a derangement in the mitochondrial metabolism of lung cells induced by severe inflammation or other uncoupling mediators. In addition, Delta a-cv lactate decrease might also reflect the anti-inflammatory activity of canakinumab. Our preliminary findings need to be confirmed by larger outcome studies. PMID: 33014462 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - October 6, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Subclinical Left Ventricular Systolic Dysfunction in Patients with Septic Shock Based on Sepsis-3 Definition: A Speckle-Tracking Echocardiography Study.
Authors: Hai PD, Phuong LL, Dung NM, Hoa LTV, Quyen DV, Chinh NX, Minh VD, Nguyen Son P Abstract Introduction: Left ventricular dysfunction is quite common in septic shock. Speckle-tracking echocardiography (STE) is a novel, highly sensitive method for assessing left ventricular function, capable of detecting subclinical myocardial dysfunction, which is not identified with conventional echocardiography. We sought to evaluate subclinical left ventricular systolic function in patients with septic shock using speckle-tracking echocardiography. Methods: From May 2017 to December 2018, patients aged ≥18 years adm...
Source: Critical Care Research and Practice - October 6, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

The Validity of SOFA Score to Predict Mortality in Adult Patients with Cardiogenic Shock on Venoarterial Extracorporeal Membrane Oxygenation.
Authors: Laimoud M, Alanazi M Abstract Background: Venoarterial ECMO is increasingly used in resuscitation of adult patients with cardiogenic shock with variable mortality reports worldwide. Our objectives were to study the variables associated with hospital mortality in adult patients supported with VA-ECMO and to determine the validity of repeated assessments of those patients by the Sequential Organ Failure Assessment (SOFA) score for prediction of hospital mortality. We retrospectively studied adult patients admitted to the cardiac surgical critical care unit with cardiogenic shock supported with VA-ECMO from J...
Source: Critical Care Research and Practice - September 25, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Maximal Glycemic Difference, the Possible Strongest Glycemic Variability Parameter to Predict Mortality in ICU Patients.
Authors: Issarawattana T, Bhurayanontachai R Abstract Background: This retrospective study aimed to determine the correlation of blood glucose and glycemic variability with mortality and to identify the strongest glycemic variability parameter for predicting mortality in critically ill patients. Methods: A total of 528 patients admitted to the medical intensive care unit were included in this study. Blood glucose levels during the first 24 hours of admission were recorded and calculated to determine the glycemic variability. Significant glycemic variability parameters, including the standard deviation, coeffici...
Source: Critical Care Research and Practice - September 12, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

The Development of Critical Care Medicine in China: From SARS to COVID-19 Pandemic.
Authors: Yin H, Wang S, Zhu Y, Zhang R, Ye X, Wei J, Hou PC Abstract Background: Critical care medicine is a branch of medical science that deals with the characteristics and regularity of life-threatening processes initiated by any injury or disease and, accordingly, relevant treatment for patients with critical illness. Conceptions of critical care medicine in China stemmed in the early 1970s. Ever since the establishment of the first intensive care unit (ICU) along with the increasingly incomparable role of ICU in medical practices, critical care medicine has become an indispensable part of the Chinese medical a...
Source: Critical Care Research and Practice - August 29, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Knowledge, Attitude, and Associated Factors towards Physical Assessment among Nurses Working in Intensive Care Units: A Multicenter Cross-Sectional Study.
Authors: Liyew B, Dejen Tilahun A, Kassew T Abstract Introduction: Nurses working in the intensive care unit play an essential role in detecting patients at risk of deterioration through ongoing assessment and action in response to changing health status. Objectives: To assess knowledge, attitude, and associated factors towards physical assessment on critically ill patients among nurses working in the intensive care unit at Amhara regional state referral hospitals, Northwest Ethiopia, 2019. The research hypothesis: there is poor physical assessment knowledge, poor physical assessment attitude, and there are fac...
Source: Critical Care Research and Practice - August 29, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Intravenous Fluid of Choice in Major Abdominal Surgery: A Systematic Review.
Conclusion: In our opinion, it is safe to give a balanced crystalloid as the maintenance fluid and give a colloid, such as HES130/0.4, 4% gelatin, or human albumin, as a volume expander. PMID: 32832150 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - August 26, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Mortality Predictors and Associated Factors in Patients in the Intensive Care Unit: A Cross-Sectional Study.
The objectives of the study were to determine the prevalence and the factors associated with the mortality and to analyze the survival. Method: A cross-sectional study conducted in two clinical and surgical ICU in the state of Sergipe, northeastern Brazil. We enrolled 316 patients with at least 48 h of hospitalization, minimum age of 18 years old, sedated or weaned, with RASS ≥ -3, between July 2017 and April 2018. We categorized data in (1) age and gender, (2) clinical condition, and (3) prevalence of delirium. Data from enrolled patients were collected from enrollment until death or ICU discha...
Source: Critical Care Research and Practice - August 19, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Continuous Estimation of Cardiac Output in Critical Care: A Noninvasive Method Based on Pulse Wave Transit Time Compared with Transpulmonary Thermodilution.
Conclusion: The accuracy and precision of the esCCOTM method were not clinically acceptable for our critical patients. EsCCOTM also failed to reliably detect changes in cardiac output. PMID: 32765907 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - August 13, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Free Fatty Acids in CSF and Neurological Clinical Scores: Prognostic Value for Stroke Severity in ICU.
Conclusion: FFA in CSF may serve as an independent prognostic biomarker for assessing the prognosis of acute ischemic stroke and the clinical outcome. It might be a useful biomarker for early detection of high-risk patients for poor outcome and hence more aggressive treatment. PMID: 32724675 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - July 31, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Cardiopulmonary Resuscitation in Interfacility Transport: An International Report Using the Ground Air Medical Quality in Transport (GAMUT) Database.
We present the first, multicenter, international report of CPR during medical transport using the large Ground and Air Medical qUality Transport (GAMUT) database. Methods: We retrospectively reviewed the GAMUT database from January 2014 to March 2017 for CPR during transport. We determined the overall CPR rate and CPR rates for adult, pediatric, and neonatal transport programs. The rate of CPR per total transports was expressed as percentage, and then, Spearman's rho nonparametric associations were determined between CPR and other quality metrics tracked in the GAMUT database. Examples include advanced airway presence,...
Source: Critical Care Research and Practice - July 24, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Efficacy of Thiamine in the Treatment of Postcardiac Arrest Patients: A Randomized Controlled Study.
Conclusions: In this study, there were no significant differences in survival outcome. Further studies with a larger population are necessary to confirm these results. PMID: 32587766 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - June 27, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Nurses' Knowledge, Attitude, and Influencing Factors regarding Physical Restraint Use in the Intensive Care Unit: A Multicenter Cross-Sectional Study.
Authors: Kassew T, Dejen Tilahun A, Liyew B Abstract Background: Physical restraint is a common practice in the intensive care units which often result in frequent skin laceration at restraint site, limb edema, restricted circulation, and worsening of agitation that may even end in death. Despite the sensitivity of the problem, however, it is felt that there are nurses' evidence-based practice gaps in Ethiopia. To emphasize the importance of this subject, relevant evidence is required to develop protocols and to raise evidence-based practices of health professionals. So, this study aimed to assess the knowledge, at...
Source: Critical Care Research and Practice - June 24, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Cardiovascular Safety of Clonidine and Dexmedetomidine in Critically Ill Patients after Cardiac Surgery.
Authors: Grest A, Kurmann J, Müller M, Jeger V, Krüger B, Spahn DR, Bettex D, Rudiger A Abstract Purpose: The aim of this retrospective study was to assess the haemodynamic adverse effects of clonidine and dexmedetomidine in critically ill patients after cardiac surgery. Methods: 2769 patients were screened during the 30-month study period. Heart rate (HR), mean arterial pressure (MAP), and norepinephrine requirements were assessed 3-hourly during the first 12 hours of the continuous drug infusion. Results are given as median (interquartile range) or numbers (percentages). Results: Patients receiv...
Source: Critical Care Research and Practice - May 28, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Acute Kidney Injury Outcomes of Elderly and Nonelderly Patients in the Medical Intensive Care Unit of a University Hospital in a Developing Country.
Conclusion: Elderly and nonelderly ICU patients showed similar survival outcomes of AKI, although the elderly were at a higher risk of requiring RRT. PMID: 32399291 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - May 15, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Early Mobilization Interventions in the Intensive Care Unit: Ongoing and Unpublished Randomized Trials.
Authors: Maheswaran J, Fromowitz J, Goldfarb M Abstract Background: Critical care societies recommend early mobilization (EM) as standard practice in the intensive care unit (ICU) setting. However, there is limited randomized controlled trial (RCT) evidence supporting EM's effectiveness. Our objective was to identify ongoing or completed RCTs assessing EM's effectiveness in the ICU. Method: We searched ClinicalTrials.gov and the Australian New Zealand Clinical Trials Registry for ongoing or completed but not published RCTs in an ICU setting with objective outcome measures. Results: There were 14 RCTs includ...
Source: Critical Care Research and Practice - May 15, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

A Predictive Model for Acute Respiratory Distress Syndrome Mortality Using Red Cell Distribution Width.
Conclusions: Adding RDW at time of ARDS diagnosis improved discrimination in a model using 4 clinical factors to predict ICU mortality. PMID: 32399293 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - May 15, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Is Mitochondrial Oxidative Stress the Key Contributor to Diaphragm Atrophy and Dysfunction in Critically Ill Patients?
Authors: Duan H, Bai H Abstract Diaphragm dysfunction is prevalent in the progress of respiratory dysfunction in various critical illnesses. Respiratory muscle weakness may result in insufficient ventilation, coughing reflection suppression, pulmonary infection, and difficulty in weaning off respirators. All of these further induce respiratory dysfunction and even threaten the patients' survival. The potential mechanisms of diaphragm atrophy and dysfunction include impairment of myofiber protein anabolism, enhancement of myofiber protein degradation, release of inflammatory mediators, imbalance of metabolic hormone...
Source: Critical Care Research and Practice - May 9, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

The Forgotten Hemodynamic (PCO2 Gap) in Severe Sepsis.
Conclusion: The PCO2 gap is an important hemodynamic variable in the management of sepsis-induced circulatory failure. The PCO2 gap can be a marker of the adequacy of the cardiac output status in severe sepsis. A high PCO2 gap value (>0.8 kPa) can identify situations in which increasing CO can be attempted with fluid resuscitation in severe sepsis. The PCO2 gap carries an important prognostic value in severe sepsis. PMID: 32377433 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - May 9, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Efficacy of Simple Eye Ointment, Polyethylene Cover, and Eyelid Taping in Prevention of Ocular Surface Disorders in Critically Ill Patients: A Randomized Clinical Trial.
Conclusion: The results of this study showed that polyethylene cover followed by simple eye ointment and eyelid taping were the most effective methods in preventing OSD. Therefore, polyethylene cover and simple eye ointment are recommended as effective eye care methods in ICU. PMID: 32351735 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - May 2, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Characterization and Outcome of Two Pediatric Intensive Care Units with Different Resources.
Conclusion: The inadequate structure and the burden of more severely ill children at the Egyptian unit appear to be the most important causes behind the higher mortality at this unit. Increasing the number of qualified staff and providing cost-effective equipment may help in improving the mortality outcome and the quality of care. PMID: 32257435 [PubMed - as supplied by publisher] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - April 8, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Early Driving Pressure Changes Predict Outcomes during Venovenous Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome.
Conclusions: We report that very early driving pressure changes can serve as an indicator of disease severity and predict patient survival following ECMO therapy. PMID: 32257436 [PubMed - as supplied by publisher] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - April 8, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Sonographic Assessment of Intravascular Fluid Estimate (SAFE) Score by Using Bedside Ultrasound in the Intensive Care Unit.
The objective of the study was to use an ultrasound-based numerical scoring system for assessment of intravascular fluid estimate (SAFE) and test its validity. Methods: A prospective, observational study was carried out in the surgical intensive care unit (ICU) of an urban tertiary care teaching hospital. Patient's intravascular volume status was assessed using the standard methods of heart rate, blood pressure, central venous pressure, cardiac output, lactate and saturation of venous oxygen, and others. This was compared with assessment using bedside ultrasound evaluation of the cardiac function, inferior vena cava, l...
Source: Critical Care Research and Practice - March 19, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Genetic Diversity of Imipenem-Resistant Acinetobacter baumannii Infections at an Intensive Care Unit.
Conclusion: Meropenem can be a therapeutic option for imipenem-resistant A. baumannii. PMID: 32148955 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - March 10, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Vasopressors and Nutrition Therapy: Safe Dose for the Outset of Enteral Nutrition?
Conclusion: It was observed that there are many controversies about the supply of EN in critically ill patients using vasopressor, especially about the safe dose, and it was not possible to identify a cutoff value for the beginning therapy. Despite the drug doses, clinical signs are still the most important parameters in the evaluation of EN tolerance. PMID: 32104602 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - February 28, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Correlation between Maximum Clot Firmness in FIBTEM and Fibrinogen Level in Critical Trauma Patients.
Authors: Khunakanan S, Akaraborworn O, Sangthong B, Thongkhao K Abstract Background: Both fibrinogen level and rotational thromboelastometry (ROTEM®) are accurate tests to demonstrate a bleeding tendency. FIBTEM® is one type of ROTEM test to determine the function of fibrinogen. An advantage of FIBTEM is helping physicians make proper decisions for blood component transfusions. However, the correlation between fibrinogen level and FIBTEM is still unclear. Objective: The aim of this study was to demonstrate a correlation between maximum clot firmness (MCF) in FIBTEM and fibrinogen level in critical traum...
Source: Critical Care Research and Practice - January 1, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Using pCO2 Gap in the Differential Diagnosis of Hyperlactatemia Outside the Context of Sepsis: A Physiological Review and Case Series.
Authors: Waldauf P, Jiroutkova K, Duska F Abstract Introduction: There is an inverse relationship between cardiac output and the central venous-arterial difference of partial pressures of carbon dioxide (pCO2 gap), and pCO2 gap has been used to guide early resuscitation of septic shock. It can be hypothesized that pCO2 gap can be used outside the context of sepsis to distinguish type A and type B lactic acidosis and thereby avoid unnecessary fluid resuscitation in patients with high lactate, but without organ hypoperfusion. Methods: We performed a structured review of the literature enlightening the physiologic...
Source: Critical Care Research and Practice - January 1, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Impact of Hyperoxia and Hypocapnia on Neurological Outcomes in Patients with Aneurysmal Subarachnoid Hemorrhage: A Retrospective Study.
Authors: Li KC, Tam CWY, Shum HP, Yan WW Abstract In recent decades, there is increasing evidence suggesting that hyperoxia and hypocapnia are associated with poor outcomes in critically ill patients with cardiac arrest or traumatic brain injury. Yet, the impact of hyperoxia and hypocapnia on neurological outcome in patients with subarachnoid hemorrhage (SAH) has not been well studied. In the present study, we evaluated the impact of hyperoxia and hypocapnia on neurological outcomes in patients with aneurysmal SAH (aSAH). Patients with aSAH who were admitted to the intensive care unit (ICU) of a tertiary hospital i...
Source: Critical Care Research and Practice - January 1, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Beta-Blocker Therapy Preserves Normal Splenic T-Lymphocyte Numbers Reduced in Proportion to Sepsis Severity in a Sepsis Model.
This study examined whether sepsis severity and beta-blocker therapy could affect the degree of T-lymphocyte cell death in a mouse model of sepsis. In the first control study, 20 animals were allocated to 4 groups: control group with sham operation (group C, n = 5) and 3 groups with cecum ligation and puncture (CLP) performed at 3 different sites: proximal, middle, and distal cecum (groups CLP-P, CLP-M, and CLP-D, respectively; n = 5 in each group). Their spleens were resected under general anesthesia 24 hours after CLP, and the total number of normal splenic T lymphocytes per mouse and the perc...
Source: Critical Care Research and Practice - January 1, 2020 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Evaluation of the Safety of Percutaneous Dilational Tracheostomy Compared with Surgical Tracheostomy in the Intensive Care Unit.
In this study, we enrolled subjects who underwent tracheostomy in our ICU between January 2012 and March 2016. We excluded subjects who were
Source: Critical Care Research and Practice - December 26, 2019 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Clinical Survey of Decreased Blood Flow Rate in Continuous Renal Replacement Therapy: A Retrospective Observational Study.
Conclusions: A decreased blood flow rate often occurs during CRRT. Clinical factors significantly associated with the occurrence of the decreased blood flow rate were not detected in the current study. Further investigation regarding the occurrence of a decreased blood flow is warranted. PMID: 31827924 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - December 13, 2019 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Performance of the Afferent Limb of Rapid Response Systems in Managing Deteriorating Patients: A Systematic Review.
Conclusions: A combination of factors affects the timely identification and response to sudden deterioration by general ward staffs, leading to suboptimal care of patients, delayed or failed activation of RRS teams, and increased risks of worsening outcomes. The research efforts and clinical involvement to improve the governance of the factors limiting the performance of the afferent limb may ensure proper management of hospitalized patients showing physiological deterioration. PMID: 31781390 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - November 30, 2019 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research

Hand Colonization with Gram-Negative Organisms of Healthcare Workers Accessing the Cardiac Intensive Care Unit: A Cross-Sectional Study at the Uganda Heart Institute.
Conclusion: Gram-negative organisms, predominantly Acinetobacter, Citrobacter, and Pseudomonas spp, were prevalent on the hands of HCWs who access the cardiac ICU irrespective of the staff category. Antimicrobial resistance was high, with multidrug resistance and carbapenem resistance common among Citrobacter spp and Acinetobacter spp, respectively. Resistance to cefepime and ciprofloxacin was low. PMID: 31687206 [PubMed] (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - November 7, 2019 Category: Intensive Care Tags: Crit Care Res Pract Source Type: research