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Condition: Septic Shock

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Total 242 results found since Jan 2013.

30-Day adverse events, length of stay and re-admissions following surgical management of pelvic/acetabular fractures
ConclusionPatients with ASA grade > II, greater co-morbidity burden and prolonged operative times were likely to experience adverse events and have a longer length of stay. Surgeons can utilize this data to risk stratify patients so that appropriate pre-operative and post-operative medical optimization can take place.
Source: Journal of Clinical Orthopaedics and Trauma - February 14, 2019 Category: Orthopaedics Source Type: research

The use of bedside echocardiography for measuring cardiac index and systemic vascular resistance in pediatric patients with septic shock
Conclusion: There was a persistently high systemic vascular resistance index in cold shock patients that influenced the stroke volume index, cardiac index, and velocity time integral. The use of echocardiograms for hemodynamic measurements is important in pediatric septic shock patients to adjust dilators, and vasopressor doses and achieve resuscitation targets in a timely manner.
Source: Revista Brasileira de Terapia Intensiva - January 17, 2019 Category: Intensive Care Source Type: research

Sepsis Update: Evidence-Based Therapy.
This article provides an overview of the current evidence of sepsis and septic shock therapy and its implementation into clinical practice. PMID: 30620955 [PubMed - in process]
Source: Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS - January 1, 2019 Category: Intensive Care Authors: Martin L, Bickenbach J, Marx G Tags: Anasthesiol Intensivmed Notfallmed Schmerzther Source Type: research

Stroke volume change after digoxin loading in septic shock patients with transient left ventricular systolic dysfunction.
In conclusion, in septic shock patients with transient LV dysfunction such as TS, digoxin loading can be a feasible treatment. Further clinical study is needed. Before Digoxin LoadingAfter Digoxin LoadingpEjection Fraction (%)20.2 ± 9.422.2 ± 10.40.327Time-Velocity Integral (cm)10.8 ± 3.112.3 ± 4.60.093LVOT diameter (cm)1.82 ± 0.241.88 ± 0.260.025Stroke Volume (mL)27.6 ± 7.933.7 ± 11.90.048
Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Lee, D. H., Jeong, J.-H., Kang, B. H., Um, S., Son, C. Tags: Acute Critical Care Source Type: research

Evaluation of Vasopressin for Vasoplegic Shock in Patients With Preoperative Left Ventricular Dysfunction After Cardiac Surgery: A Propensity-Score Analysis
Conclusions: Compared with norepinephrine, vasopressin could not improve the postoperative outcomes in patients with pLVD after cardiac surgery. Vasopressin should be cautious to be used as a first-line vasopressor agent in postcardiac vasoplegic shock.
Source: Shock - October 16, 2018 Category: Emergency Medicine Tags: Clinical Science Aspects Source Type: research

Risk of incident atrial fibrillation after a prior critical illness: A retrospective cohort study.
CONCLUSIONS: Our study explored incident AF among patients with critical illness in their medical history. Patients with septicemia/septic shock were at the highest risk of developing new-onset AF among these critically ill patients. PMID: 30243509 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - September 19, 2018 Category: Internal Medicine Authors: Hu WS, Lin CL Tags: Eur J Intern Med Source Type: research

Cardiovascular Parameters Associated With Troponin I as Indicators for 14-Day Mortality in Patients With Septic Shock.
CONCLUSIONS: Our data give an insight into interactions between cardiac and hemodynamic factors to cause cardiocyte damage and suggest that multiple factors (i.e., low CFI and high SVV) should be considered together to evaluate cardiocyte damage and mortality in sepsis. PMID: 30286819 [PubMed - in process]
Source: The American Journal of the Medical Sciences - September 1, 2018 Category: General Medicine Authors: Su WL, Shui HA, Lan CC, Yang MC, Hsieh CA, Jang SJ, Chung HW, Wu YK Tags: Am J Med Sci Source Type: research

Transporting Patients to Appropriate Receiving Destinations
Conclusion EMS is in a position to be the initiator of specialty center destination. In large cities with multiple hospitals, EMS should transport patients to the closest, most appropriate facility based on patient condition, even if this requires passing a closer facility. Where there are hospitals with multiple specialty services, EMS may be asked to activate a specific team, such as the stroke or cardiac team. In rural communities, EMS can communicate with the local hospital and by letting the hospital know of patient condition, help start the interfacility transport process from the field....
Source: JEMS Special Topics - July 19, 2018 Category: Emergency Medicine Authors: Dennis Edgerly, MEd, EMT-P Tags: Exclusive Articles Columns Operations Source Type: news

Deadly Respiratory Distress Mimic
Conclusion It’s important for prehospital providers to be able to differentiate metabolic disturbances in the setting of respiratory distress and not be fooled into thinking tachypnea always has a respiratory cause. The physical exam and adjuncts such as end-tidal capnography can assist in the prehospital diagnosis. A COPD exacerbation generally presents as diminished lung sounds, wheezing on exhalation, and a prolonged expiratory phase. Here, a patient will attempt to compensate for the inflammation and mucus accumulation associated with the destruction and narrowing of peripheral airways and a subsequent lack of availa...
Source: JEMS Special Topics - July 17, 2018 Category: Emergency Medicine Authors: Brenton Faber, PhD, NRP Tags: Airway & Respiratory Exclusive Articles Patient Care Source Type: news

Pulse-induced contour cardiac output (PiCCO) combined with passive leg raising test predicting fluid resuscitation in adult patients with septic shock
Publication date: Available online 17 July 2017Source: The Kaohsiung Journal of Medical SciencesAuthor(s): Si-Dong ZhanAbstractTo investigate the clinical value of pulse-induced contour cardiac output (PiCCO) monitoring combined with passive leg raising (PLR) test in predicting fluid responsiveness so as to guide fluid resuscitation in adult septic shock patients managed by rehydration test. One hundred and forty five adult septic shock patients, who were informed to receive PLR tests and rehydration tests. Patients were divided into two groups based on the observation of fluid responsiveness in the rehydration test. Param...
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

Heartfelt sepsis: microvascular injury due to genomic storm.
Abstract Sepsis is one of the ten leading causes of death in developed and developing countries. In the United States, sepsis mortality approaches that of acute myocardial infarction and exceeds deaths from stroke. Neonates and the elderly are the most vulnerable patients, with these groups suffering from the highest sepsis mortality. In both groups, many survivors respectively display serious developmental disabilities and cognitive decline. The National Institute of Health National Heart Lung and Blood Institute Panel redefined sepsis as a "severe endothelial dysfunction syndrome in response to intravascular and...
Source: Polish Heart Journal - July 5, 2018 Category: Cardiology Authors: Hawiger J Tags: Kardiol Pol Source Type: research

Sepsis-induced myocardial dysfunction
Purpose of review Sepsis leads to a complex intramyocardial inflammatory response that results in sepsis-induced myocardial dysfunction. Here, recent findings are reviewed in a physiologic context. Recent findings Decreased systolic contractility during sepsis limits ventricular ejection and stroke volume. Initially, this effect is compensated for by increased diastolic filling during volume resuscitation. Reduced afterload due to arterial vasodilation also compensates so that cardiac output can be maintained or increased. Recent results recognize the importance of diastolic dysfunction, reduced ventricular diastolic ...
Source: Current Opinion in Critical Care - July 2, 2018 Category: Nursing Tags: CARDIOVASCULAR SYSTEM: Edited by Stephen M. Pastores Source Type: research

Clinical - microbiological characterization and risk factors of mortality in infective endocarditis from a tertiary care academic hospital in Southern India.
CONCLUSIONS: This study reiterates the persistent dominance of rheumatic heart disease in the population studied and α - hemolytic Streptococci as the commonest responsible microorganism. PMID: 29716704 [PubMed - in process]
Source: Indian Heart J - March 1, 2018 Category: Cardiology Authors: Subbaraju P, Rai S, Morakhia J, Midha G, Kamath A, Saravu K Tags: Indian Heart J Source Type: research

Photoluminescence intensity ratio of Eu ‐conjugated lactates—A simple optical imaging technique for biomarker analysis for critical diseases
Instant measurement of elevated biomarkers such as lactic acid offers the most promising approaches for early treatment and prevention of many critical diseases including cardiac arrest, stroke, septic shock, trauma, liver dysfunction, as well as for monitoring lactic acid level during intense exercise. In the present study, a unique dependence of visible photoluminescence of Eu3+ ions resulting from 5D0 to 7FJ(J = 0,1,2,3,4) transitions, which can be exploited for rapid detection of biomarkers, both in vitro and ex vivo, has been reported. It is observed that the integrated intensity ratio of photoluminescence signals...
Source: Journal of Biophotonics - December 18, 2017 Category: Physics Authors: Tarun Kakkar, Nikita Thomas, Eric Kumi ‐Barimah, Gin Jose, Sikha Saha Tags: FULL ARTICLE Source Type: research