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Condition: Septic Shock

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Total 242 results found since Jan 2013.

Challenges in Sepsis Care
There are 2 important recent changes in sepsis care. The first key change is the 2016 Sepsis-3 definitions from the recent consensus workgroup with new sepsis and septic shock definitions. Useful tools for assessing patients that have a greater risk of mortality include Sequential Organ Failure Assessment (SOFA) in intensive care units and quick SOFA outside intensive care units. The second change involves management of fluid resuscitation and measures of volume responsiveness. Measures such as blood pressure and central venous pressure are not reliable. Fluid challenges and responsiveness should be based on stroke volume ...
Source: Critical Care Nursing Clinics of North America - September 25, 2016 Category: Nursing Authors: Maureen A. Seckel, Thomas Ahrens Source Type: research

South Carolina EMS Integrates In-Hospital Sepsis Care into Protocols
Medic 29 is dispatched to a college dorm for a female with chief complaint of lower abdominal and flank pain for the past five days. The dorm room appears clean and well kept. The patient appears to be a typical 18-year-old college student. She's lying on her bed and is responsive to verbal stimuli, hot to touch, and tachycardic with weak and thready radial pulses at 128. She reports painful urinating for the past 48 hours, general malaise, weakness and nausea. She appears to have labored respirations with a room air SpO2 reading of 95% and is hypotensive with a systolic blood pressure of 88 mmHg that remains low during tr...
Source: JEMS Patient Care - September 1, 2016 Category: Emergency Medicine Authors: Jason G. Walchok, NRP, FP-C Tags: Patient Care Source Type: news

Predictors of 30-day mortality following hip/pelvis fractures
Discussion Several preoperative patient risk factors and postoperative complications greatly increased the odds for patient mortality following 30-days after initial surgery. Orthopaedic surgeons can utilize these predictive risk factors to better improve patient care. Level of evidence Retrospective study. Level IV.
Source: Orthopaedics and Traumatology: Surgery and Research - August 3, 2016 Category: Orthopaedics Source Type: research

Longitudinal Study of the Effects of Bacteremia and Sepsis on 5-year Risk of Cardiovascular Events
Conclusions. Prior instances of bacteremia and sepsis substantially increase the 5-year risk of CV events.
Source: Clinical Infectious Diseases - July 30, 2016 Category: Infectious Diseases Authors: Jafarzadeh, S. R., Thomas, B. S., Warren, D. K., Gill, J., Fraser, V. J. Tags: ARTICLES AND COMMENTARIES Source Type: research

Muhammed Ali's Death Underscores Importance of Prehospital Sepsis Detection
Muhammad Ali, one of the greatest athletes of all times and a world-class treasure, passed away on Friday, June 3, 2016, as result of sepsis. Imagine if an EMS crew could have detected that he was becoming septic and was able to treat him in the field, helping the hospital attack this deadly condition before it attacked his vital organs? Soon, crews all over the world will be capable of doing so. Severe sepsis is caused by overwhelming infection, and is responsible for significant morbidity and mortality among hospitalized patients. Clinical identification of sepsis includes two or more of the systemic inflammatory respons...
Source: JEMS Patient Care - June 6, 2016 Category: Emergency Medicine Authors: A.J. Heightman, MPA, EMT-P Tags: Patient Care Source Type: news

High Serum sTREM-1 Correlates With Myocardial Dysfunction and Predicts Prognosis in Septic Patients.
CONCLUSIONS: Myocardial dysfunction is common in patients with severe sepsis and septic shock and high serum levels of sTREM-1 correlates with myocardial dysfunction to some extent but is not an independent predictor, which more importantly showed prognostic value for septic shock outcome. PMID: 27238916 [PubMed - in process]
Source: The American Journal of the Medical Sciences - May 31, 2016 Category: Journals (General) Authors: Li Z, Zhang E, Hu Y, Liu Y, Chen B Tags: Am J Med Sci Source Type: research

French Intensive Care Society, International congress - Réanimation 2016.
C, Sauneuf B, Verrier P, Pottier V, Orabona M, Samba D, Viquesnel G, Lermuzeaux M, Hazera P, Hanouz JL, Parienti JJ, Du Cheyron D, Demoule A, Clavel M, Rolland-Debord C, Perbet S, Terzi N, Kouatchet A, Wallet F, Roze H, Vargas F, Guérin C, Dellamonica J, Jaber S, Similowski T, Quenot JP, Binquet C, Vinsonneau C, Barbar SD, Vinault S, Deckert V, Lemaire S, Hssain AA, Bruyère R, Souweine B, Lagrost L, Adrie C, Jung B, Daurat A, De Jong A, Chanques G, Mahul M, Monnin M, Molinari N, Lheureux O, Trepo E, Hites M, Cotton F, Wolff F, Surin R, Créteur J, Vincent JL, Gustot T, Jacobs F, Taccone FS, Neuville M, Timsit JF, El-Hel...
Source: Australian Family Physician - May 31, 2016 Category: Primary Care Authors: Jaillette E, Girault C, Brunin G, Zerimech F, Chiche A, Broucqsault-Dedrie C, Fayolle C, Minacori F, Alves I, Barrailler S, Robriquet L, Delaporte E, Thellier D, Delcourte C, Duhamel A, Nseir S, Valette X, Desmeulles I, Savary B, Masson R, Seguin A, Daubi Tags: Ann Intensive Care Source Type: research

Impact of Compliance with a Sepsis Resuscitation Bundle in a Portuguese Emergency Department.
CONCLUSIONS: The compliance with a sepsis resuscitation bundle starting in the emergency department was positively associated with the outcomes of the septic patients. Nonetheless the bundle was unreliably performed. PMID: 27234947 [PubMed - in process]
Source: Acta Medica Portuguesa - May 29, 2016 Category: Journals (General) Tags: Acta Med Port Source Type: research

Levosimendan Versus Dobutamine in Myocardial Injury Patients with Septic Shock: A Randomized Controlled Trial.
CONCLUSIONS Compared with dobutamine, levosimendan reduces biomarkers of myocardial injury and improves systemic hemodynamics in patients with septic shock. However, it does not reduce the days on mechanical ventilation, length of stay in ICU and hospital, or 28-day mortality. PMID: 27138236 [PubMed - in process]
Source: Medical Science Monitor - May 5, 2016 Category: Research Tags: Med Sci Monit Source Type: research

Pre-operative stroke and neurological disability do not independently affect short- and long-term mortality in infective endocarditis patients
Conclusions Pre-operative stroke and the severity of neurological disability do not independently affect short- and long-term mortality in patients with infective endocarditis. It appears that patients with pre-operative stroke present with a generally higher risk profile. This information may substantially affect decision-making.
Source: Clinical Research in Cardiology - April 26, 2016 Category: Cardiology Source Type: research

Patty Duke's Death Announcement Is A Milestone For Sepsis Awareness
Oscar-winning actress Patty Duke, star of "The Patty Duke Show" and the Broadway play and film “The Miracle Worker,” died of sepsis from a ruptured intestine on Tuesday. Simple though it may seem, her death announcement is a major milestone for the sepsis awareness movement, said Thomas Heymann, executive director of the Sepsis Alliance. The more people are aware of this condition, Heymann said, the stronger their likelihood of saving their own lives or the lives of their loved ones. "The fact that they said Patty Duke’s cause of death was sepsis is relatively new," Heymann said. "It very often ...
Source: Science - The Huffington Post - March 30, 2016 Category: Science Source Type: news

A successful percutaneous mechanical vegetation debulking used as a bridge to surgery in acute tricuspid valve endocarditis.
We present a case of a 24-year-old male with a history of intravenous drug abuse, who was referred to our center after 10 days of medical management of acute infective endocarditis. Upon arrival he was in septic shock, multi-organ failure, and mobile vegetations on the tricuspid valve with severe tricuspid regurgitation. He also had bilateral pulmonary infarcts and an ischemic stroke in the right parietal lobe. A successful percutaneous transcatheter mechanical vegetation debulking was performed followed by surgical valve replacement seven days later. This case introduces a new option in the management of right-sided endoc...
Source: Journal of Thoracic Disease - February 25, 2016 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Comparing transesophageal Doppler corrected systolic flow time versus central venous pressure as a guide for fluid resuscitation in septic shock
Conclusion Transesophageal aortic Doppler is a simple, non-invasive tool of guiding fluid therapy in patients with severe sepsis and septic shock. FTC change was a better predictor of fluid responsiveness than CVP in septic shock. There was higher significant difference in SV after resuscitation when using FTC as guidance.
Source: Egyptian Journal of Anaesthesia - January 23, 2016 Category: Anesthesiology Source Type: research

N-terminal-pro-brain natriuretic peptide elevations in the course of septic and non-septic shock reflect systolic left ventricular dysfunction assessed by transpulmonary thermodilution
Conclusions In septic and non-septic shock, NT-proBNP elevations reflect systolic left ventricular dysfunction and are associated with a poor outcome. They may help recognition of cardiac dysfunction in shock and its management when invasive hemodynamic monitoring is not yet instituted.
Source: IJC Metabolic and Endocrine - January 17, 2016 Category: Endocrinology Source Type: research