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Condition: Septic Shock

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Total 242 results found since Jan 2013.

Transfusion strategy in hematological intensive care unit: study protocol for a randomized controlled trial
Background: Packed red blood cell (PRBC) transfusion is required in hematology patients treated with chemotherapy for acute leukemia, autologous (auto) or allogeneic (allo) hematopoietic stem cell transplantation (HSCT). In certain situations like septic shock, hip surgery, coronary disease or gastrointestinal hemorrhage, a restrictive transfusion strategy is associated with a reduction of infection and death. A transfusion strategy using a single PRBC unit has been retrospectively investigated and showed a safe reduction of PRBC consumption and costs. We therefore designed a study to prospectively demonstrate that the tra...
Source: Trials - November 23, 2015 Category: Journals (General) Authors: Sylvain ChantepieJean-Baptiste MearLydia GuittetBenoît DervauxJean-Pierre MarolleauFabrice JardinJean-Jacques DutheilJean-Jacques ParientiJean-Pierre VilqueOumedaly Reman Source Type: research

Clinical experience of infective endocarditis complicated by acute cerebrovascular accidents.
CONCLUSION: Early surgical intervention for IE with ischemic stroke may prevent adverse events, particularly in patients with impaired renal function, diabetes, or staphylococcal infection. A delay in operation of > 30 days is recommended after hemorrhagic stroke. PMID: 26610865 [PubMed - as supplied by publisher]
Source: Asian Journal of Surgery - November 20, 2015 Category: Surgery Authors: Hsu CY, Chi NH, Wang SS, Chen YS, Yu HY Tags: Asian J Surg Source Type: research

Emergency Department Management of Sepsis Patients: A Randomized, Goal-Oriented, Noninvasive Sepsis Trial
Conclusion Protocol-based fluid resuscitation of patients with severe sepsis and septic shock with the noninvasive cardiac output monitor and passive leg-raising maneuver did not result in better outcomes compared with usual care. Future studies to demonstrate the use of the noninvasive protocol-based care in patients with preexisting fluid overload states may be warranted.
Source: Annals of Emergency Medicine - October 24, 2015 Category: Emergency Medicine Source Type: research

Risk of type 2 diabetes mellitus in patients with acute critical illness: a population-based cohort study
Conclusion Our results suggest that patients with certain critical illnesses are associated with a high risk of developing T2DM. Clinicians should be aware of this association and intensively screen for T2DM in patients following diagnosis of critical illness.
Source: Intensive Care Medicine - September 14, 2015 Category: Intensive Care Source Type: research

Time course of cytokines, hemodynamic and metabolic parameters during hyperthermic intraperitoneal chemotherapy.
CONCLUSION: The most significant variations are those of IL-6 and PCT. The cytokines level parallel the hemodynamic derangements. Treatment during HIPEC should mimic the established treatment during sepsis and septic shock. PMID: 26154446 [PubMed - as supplied by publisher]
Source: Minerva Anestesiologica - July 13, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

The comparison of stroke volume variation with central venous pressure in predicting fluid responsiveness in septic patients with acute circulatory failure
Conclusions: When predicting fluid responsiveness in mechanically ventilated patients in septic shock, SVV is more effective than CVP. Nevertheless, the overall correlation of baseline SVV with increases in CI remains poor. Trends in SVV, as reflected by decreases with volume replacement, seem to correlate much better with increases in CI.
Source: Indian Journal of Critical Care Medicine - July 8, 2015 Category: Intensive Care Authors: Santhalakshmi AngappanSatyen ParidaArumugam VasudevanAshok Shankar Badhe Source Type: research

Respiratory variation in carotid peak systolic velocity predicts volume responsiveness in mechanically ventilated patients with septic shock: a prospective cohort study
Conclusions ΔCDPV can be more accurate than other methods for assessing fluid responsiveness in patients with septic shock receiving lung protective mechanical ventilation. ΔCDPV also has a high correlation with SVI increase after fluid challenge.
Source: Critical Ultrasound Journal - June 26, 2015 Category: Radiology Source Type: research

Effects of fluid administration on arterial load in septic shock patients
Conclusion Fluid administration significantly reduced arterial load in critically patients with septic shock and acute circulatory failure, even when increasing cardiac output. This explains why some septic patients increase their cardiac output after fluid administration without improving blood pressure.
Source: Intensive Care Medicine - June 11, 2015 Category: Intensive Care Source Type: research

Early prediction and outcome of septic encephalopathy in acute stroke patients with nosocomial coma.
CONCLUSION: High fever and severe SIRS are two early predictors of stroke patients with SE, and survival rates were worse in stroke patients with SE than those without SE. PMID: 26015818 [PubMed]
Source: Clin Med Res - May 29, 2015 Category: Research Authors: Tong DM, Zhou YT, Wang GS, Chen XD, Yang TH Tags: J Clin Med Res Source Type: research

In-hospital mortality risk factors for patients with cerebral vascular events in infectious endocarditis. A correlative study of clinical, echocardiographic, microbiologic and neuroimaging findings.
CONCLUSIONS: In patients with IE complicated with stroke, the number of lesions observed in neuroimaging examinations and conservative treatment were associated with higher in-hospital mortality. PMID: 26031364 [PubMed - as supplied by publisher]
Source: Archivos de Cardiologia de Mexico - May 29, 2015 Category: Cardiology Authors: González-Melchor L, Kimura-Hayama E, Díaz-Zamudio M, Higuera-Calleja J, Choque C, Soto-Nieto GI Tags: Arch Cardiol Mex Source Type: research

Effects of early hemodynamic resuscitation on left ventricular performance and microcirculatory function during endotoxic shock
Background: Microcirculation and macrohemodynamics are severely compromised during septic shock. However, the relationship between these two compartments needs to be further investigated. We hypothesized that early resuscitation restores left ventricular (LV) performance and microcirculatory function but fails to prevent metabolic disorders. We studied the effects of an early resuscitation protocol (ERP) on LV pressure/volume loops-derived parameters, sublingual microcirculation, and metabolic alterations during endotoxic shock. Methods: Twenty-five pigs were randomized into three groups: LPS group: Escherichia coli lipopo...
Source: Intensive Care Medicine Experimental - May 8, 2015 Category: Surgery Authors: Alejandra LópezJuan GrignolaMartín AnguloIgnacio AlvezNicolás NinGonzalo LacuestaManuel BazPablo CardinalIvana PrestesJuan BouchacourtJuan RivaCan InceFrancisco Hurtado Source Type: research

Predictors of Patients Who Present to the Emergency Department With Sepsis and Progress to Septic Shock Between 4 and 48 Hours of Emergency Department Arrival*
Conclusion: Approximately 12% of septic emergency department patients develop shock within 48 hours of presentation, and more than half of these patients develop shock after the first 4 hours of emergency department arrival. Over a third of patients who have sepsis within 4 hours of emergency department arrival and develop septic shock between 4 and 48 hours of emergency department arrival are not admitted to an ICU.
Source: Critical Care Medicine - April 17, 2015 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Symptomatic Cerebral Air Embolism after Central Venous Catheter Removal. (P1.034)
CONCLUSIONS: Central air embolism is a rare complication of central venous catheter removal or insertion. GRE or DWI is useful for diagnosis of cerebral air embolism. Clinician should be aware of this uncommon complication and take the necessary precaution to prevent it.Disclosure: Dr. Ferdous has nothing to disclose. Dr. Tantikittichaikul has nothing to disclose. Dr. Hasan has nothing to disclose. Dr. Eldokla has nothing to disclose. Dr. Kim has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ferdous, J., Tantikittichaikul, S., Hasan, R., Eldokla, A., Kim, J. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

FloTrac® Monitoring System: What Are Its Uses in Critically Ill Medical Patients?
Abstract: The FloTrac®/Vigileo device uses arterial pressure waveform analysis to calculate stroke volume and cardiac output; it does not require calibration against an independent measurement of cardiac output. Consequently, it provides a method to determine hemodynamic status, changes in the clinical course and responses to therapeutic interventions in patients who have arterial catheters in place. These devices perform relatively well in stable patients undergoing surgery and having an acceptable percentage error in differences between the FloTrac® device and invasive monitoring using pulmonary catheters. However, in ...
Source: The American Journal of the Medical Sciences - March 31, 2015 Category: Journals (General) Tags: Review Article Source Type: research

Stroke is not a treatment dilemma for early valve surgery in active infective endocarditis.
CONCLUSION: Surgery for AIE with cerebral septic embolisms can be performed safely, with good early and mid-term follow-up results. When urgent or emergent surgery for AIE is needed, neurologic complications should not be a reason for delay. PMID: 25799711 [PubMed - in process]
Source: Journal of Heart Valve Disease - March 25, 2015 Category: Cardiology Tags: J Heart Valve Dis Source Type: research