Average Aortic Valve Sclerosis Score Index as a Marker for Significant Coronary Artery Disease in Patients with Non-ST-Elevation Myocardial Infarction or Unstable Angina.
CONCLUSIONS: The average AVSSI may be a useful marker in the risk stratification of acute coronary syndrome patients, and is consistent with other high-risk echocardiographic variables, the presence of significant CAD, and more complex coronary artery lesions. PMID: 30560593 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - December 19, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Clinical Significance of Greater Implantation Height with SAPIEN 3 Transcatheter Heart Valve.
CONCLUSIONS: Among TAVR patients who received the SAPIEN 3 heart valve, a higher AIH (≥0.85) was not associated with a lower rate of PPM implantation or increased operative mortality. Prior RBBB was the only independent risk factor for new PPM implantation. Long-term follow up is crucial in determining the clinical significance of PPM implantation. PMID: 30560594 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - December 19, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Immediate and Long-Term Follow Up Results of Balloon Aortic Valvuloplasty in Congenital Bicuspid Aortic Valve Stenosis Among Young Patients.
Authors: Ananthakrishna Pillai A, Rangaswamy Balasubramanian V, Kanshilal Sharma D Abstract BACKGROUND: The study aim was to investigate the immediate and long-term results of balloon aortic valvuloplasty (BAV) in young patients (aged ≤20 years) with congenital bicuspid aortic valve presenting with severe aortic stenosis. METHODS: The study involved a single tertiary care center-based retrospective data analysis of immediate and long-term outcomes in patients following balloon valvuloplasty between 2000 and 2011. A total of 92 young patients (mean age 12.7 years; 95% CI 8.3-16.7 years) with aortic stenosis d...
Source: Journal of Heart Valve Disease - December 19, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Evolution of Veterans Affairs Transcatheter Aortic Valve Replacement Program: The First 100 Patients.
CONCLUSIONS: Successful outcomes were demonstrated for a VA TAVR program that compared favorably with benchmarks established by the National Transcatheter Valve Therapies Registry. These results provide a necessary transparency of TAVR outcomes at a federal institution. PMID: 30560596 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - December 19, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

In-Vivo Evaluation of Flexible Mitral Annuloplasty Rings: Are They All the Same?
Authors: Rasmussen J, Nielsen Skov S, Ropcke DM, Juan Tjoernild M, Ilkjaer C, Lyager Nielsen S Abstract BACKGROUND: Currently, several different flexible mitral annuloplasty rings are available, and their efficacy for surgical repair of the mitral valve is, in general, considered equal. However, clinical experience indicates differences in remodeling capacity that have not yet been quantitatively assessed. The study aim was to compare the biomechanical properties of two commonly used flexible mitral annuloplasty rings in an acute pig model. METHODS: Medtronic Simulus Flex (n = 5) and Medtronic Duran AnCore (n =...
Source: Journal of Heart Valve Disease - December 19, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

New Mitral Valve Annuloplasty Concept: Optimizing Annular Dynamics and Force Distribution.
Authors: Jensen MO, Jensen H, Skov SN, Levine RA, Nygaard H, M Hasenkam J, Nielsen SL Abstract BACKGROUND: Temporal three-dimensional (3D) analysis of the mitral valve biomechanics has prompted a re-evaluation of surgical approaches and repair device designs to accommodate the natural dynamics of the valve. Such new designs strive to obtain lower annulus restraining forces, resulting in more natural leaflet and chordal stresses. A new annuloplasty system was evaluated using 3D motion and out-of-plane force analysis. It was hypothesized that this system would not impact the valve with adverse motion restrictions or ...
Source: Journal of Heart Valve Disease - December 19, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Mitral Valve Repair with a Semi-Rigid C-Band Annuloplasty Ring in Ischemic Mitral Regurgitation: Still a Viable Surgical Option?
Authors: Saitto G, Lio A, Russo M, Nicolò F, Bassano C, Scafuri A, Nardi P, Ruvolo G Abstract BACKGROUND: Ischemic mitral valve regurgitation (IMR) develops in approximately 10% of patients after myocardial infarction. Surgical management of IMR is controversial, as many series have failed to demonstrate the superiority of mitral valve repair (MVRep) over mitral valve replacement (MVR) in IMR. Moreover, in the setting of MVRep, the choice of ring type is the subject of much debate. The study aim was to evaluate the results of MVRep in IMR with the use of a semi-rigid incomplete C-ring. METHODS: Between J...
Source: Journal of Heart Valve Disease - December 19, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

The Influence of Warfarin Adherence on Time in Therapeutic Range Among Patients with Mechanical Heart Valves.
Authors: Ozkaramanli Gur D, Baykız D, Akyuz A, Alpsoy S, Fidan C Abstract BACKGROUND: Despite considerations of its therapeutic range and multiple drug-food interactions, warfarin is the mainstay of oral anticoagulation in patients with mechanical heart valves (MHVs). The quality of anticoagulation demonstrates variations, with 'time in therapeutic range' (TTR) values usually lower than expected. It has been hypothesized that warfarin adherence is among the modifiable causes of suboptimal coagulation. The aim of the study was to demonstrate the ability of the 8-Item Morisky Medication Adherence Scale (MMAS-8©...
Source: Journal of Heart Valve Disease - December 19, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Relationship Between Pulmonary Venous Flow and Prosthetic Mitral Valve Thrombosis.
Authors: Cerşit S, Gündüz S, Ozan Gürsoy M, Karakoyun S, Kalçık M, Bayam E, Yesin M, Özkan M Abstract BACKGROUND: Prosthetic valve thrombosis (PVT) may impair pulmonary venous flow (PVF) and left atrial appendage (LAA) functions. An investigation was conducted to determine the association between left superior PVF and LAA functions and mitral PVT. METHODS: This observational case-control study included 100 consecutive patients (87 females, 13 males; mean age 59 years; range 35-71 years) with mechanical mitral PVT, and 50 age- and gender-matched otherwise healthy controls with normal...
Source: Journal of Heart Valve Disease - December 19, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Brachial-Ankle Pulse Waves Reflect the Hemodynamics of Valvular Heart Disease.
Authors: Kurimoto R, Shiraishi H, Taniguchi T, Otakara A, Nakanishi N, Zen K, Nakamura T, Yamano T, Shirayama T, Yaku H, Matoba S Abstract BACKGROUND: Brachial-ankle pulse wave (ba-PW) analysis is an established technique for assessing arterial stiffness and cardiovascular risk. The peripheral arterial pulse wave configuration may be useful for valvular heart disease (VHD) detection because it is closely related to the physical signs of VHD; however, few reports have been made assessing the efficacy of ba-PW analysis for VHD screening. METHODS: Consecutive VHD patients scheduled for valve surgery were enrolled ...
Source: Journal of Heart Valve Disease - December 19, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Sociodemographic, Clinical and Patient-Reported Outcomes and Readmission After Heart Valve Surgery.
CONCLUSIONS: Readmission rates after heart valve surgery are high and often seen in patients who have undergone PCI and heart failure before surgery. Predictors for these high readmissions rates are difficult to establish based on medical history and type of surgery. PROs at discharge contribute information regarding a patient's perception of their often poor quality of life, but do not predict readmission. PMID: 30560603 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - December 19, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Early Hemodynamic Performance of the Crown PRT Aortic Prosthesis: A Prospective Study.
CONCLUSIONS: The Crown PRT is an effective bioprosthesis, with a low incidence of valve-related complications comparable to those of other current bioprostheses. The bioprosthesis demonstrated satisfactory results in terms of hemodynamics and freedom from reoperation. PMID: 30560604 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - December 19, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Excellent Durability of the Mosaic Porcine Aortic Bioprosthesis at Extended Follow Up.
CONCLUSIONS: The Mosaic bioprosthesis has shown excellent durability over two decades of clinical use, with a negligible incidence of valve degeneration and need for reoperation. Thus, it may be considered a valid option for AVR, especially in elderly patients. PMID: 30560605 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - December 19, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

TAVI as Therapy of Choice for Aortic Valve Disease in Osteogenesis Imperfecta.
Authors: Minol JP, Zeus T, Blehm A, Veulemans V Abstract Osteogenesis imperfecta (OI) is a syndrome that is often associated with dysfunction of the aortic valve. Because of the resultant fragile vessels and impaired hemostasis, surgical therapy to treat OI is challenging. Previous reports have suggested that transcatheter aortic valve implantation (TAVI) might be a suitable treatment for this condition. To the best of the authors' knowledge, the present case is the first to describe a young patient who underwent successful TAVI to treat osteogenesis imperfecta. The proposal of transfemoral TAVI serving as first-li...
Source: Journal of Heart Valve Disease - December 19, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Treatment of Simultaneous Thromboembolism of the Right and Left Coronary Arteries with Thrombus Aspiration in a Patient with a Prosthetic Mitral Valve.
Authors: Sığırcı S, Keskin K, Sezai Yıldız S, Aksan G, Bambul Sığırcı B, Orta Kılıçkesmez K Abstract Prosthetic heart valve thrombosis is a rare, difficult-to-treat condition that increases morbidity and mortality by leading to systemic embolism. Clinically, it presents mainly in the form of stroke, though an embolism be observed in many systems. Acute coronary syndrome, which is rarely observed in patients with a prosthetic heart valve, mostly occurs as non-ST segment elevation myocardial infarction (MI). There is no specific recommendation for the treatment of this condition. Revascularization ...
Source: Journal of Heart Valve Disease - December 19, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Mitral Chordae Rupture as a Possible First-Time Presentation for Graves ’ Disease.
Mitral Chordae Rupture as a Possible First-Time Presentation for Graves’ Disease. J Heart Valve Dis. 2018 Jan;27(1):110-113 Authors: Ghazal SN, Alarfaj MK Abstract Graves' disease is a common cause of hyperthyroidism that can lead to multiple cardiovascular complications. Herein is described the case of a 44-year-old male who presented with new-onset atrial fibrillation and mitral regurgitation secondary to flail anterior mitral leaflet with chordae tendineae rupture. This is a rare complication for Graves' disease, and has been reported only twice previously. It was hypothesized that this complicatio...
Source: Journal of Heart Valve Disease - December 19, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

MitraClip ® Repair in Cardiogenic Shock Due to Acute Mitral Regurgitation: From Near-Death to Walking.
MitraClip® Repair in Cardiogenic Shock Due to Acute Mitral Regurgitation: From Near-Death to Walking. J Heart Valve Dis. 2018 Jan;27(1):114-116 Authors: Hernández-Enríquez M, Freixa X, Sanchis L, Regueiro A, Burgos F, Navarro R, Masotti M, Sitges M, Sabaté M Abstract A patient with ischemic myocardiopathy who had undergone resynchronization therapy was admitted to the authors' institution with progressive dyspnea. Echocardiography demonstrated a left ventricular ejection fraction (LVEF) of 25%, with a massive mitral regurgitation (MR) secondary to anterior leaflet prolapse and ...
Source: Journal of Heart Valve Disease - December 19, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Management of Late Paravalvular Leak after Transcatheter Valve Placement in Calcified Mitral Annulus.
Authors: Macfie R, Song H, Bruch G, Chadderdon S, Zahr F Abstract Mitral annular calcification presents a unique challenge to the surgical and interventional management of mitral valve pathology. Herein are presented the details of an emerging use of transcatheter valve replacement not only to salvage an open operation but also to minimize the important late complications of valve migration, resulting in paravalvular leak (PVL). The valve was initially stabilized with balloon valvuloplasty to prevent further migration; a vascular plug was then used to close the PVL. Teams treating complex valvular pathology with tr...
Source: Journal of Heart Valve Disease - December 19, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Use of AngioVac for Removal of Tricuspid Valve Vegetation.
Authors: Wallenhorst P, Rutland J, Gurley J, Guglin M Abstract The use is reported of the AngioVac system to resolve a case of persistent bacteremia in the setting of MRSA tricuspid valve infective endocarditis. The infection was secondary to intravenous drug use in a patient who had failed multiple antibiotic regimens and was deemed a poor surgical candidate. PMID: 30560611 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - December 19, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Double Valve Failure Due to Perceval Sutureless Aortic Valve Migration.
Authors: Rossi M, Cristodoro L, Roger D, Pennisi V, Pisano G, Fratto P Abstract A 76-year-old woman was admitted to the authors' hospital with pulmonary edema five months after the successful implantation of a Perceval sutureless aortic valve (Sorin Group Srl, Saluggia, Italy). Both echocardiography and computed tomography scanning demonstrated migration of the aortic valve into the left ventricle, causing severe aortic and mitral (secondary) insufficiency. Following heart team discussions, the sutureless valve was replaced with a standard bioprosthesis (Perimount, Magna Ease; Edwards Lifesciences, Irvine, Californ...
Source: Journal of Heart Valve Disease - December 19, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Aortic Valve Prolapse and Aortic Regurgitation During Long-Term Follow Up in Children with Ventricular Septal Defect.
CONCLUSIONS: Frequent (six-month) echocardiographic evaluation in patients with perimembraneous or muscular outlet VSD after AVP and AR development may be useful. In addition, surgical intervention in patients with perimembraneous or muscular outlet VSD, AVP and mild AR may prevent the worsening of AR. PMID: 30207110 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Electrocardiographic Correlates of Myocardial Injury After Transcatheter Aortic Valve Replacement.
Authors: Worku B, de Biasi A, Horowitz J, Kampaktsis P, Elmously A, Minutello R, Wong SC, Salemi A Abstract BACKGROUND: Transcatheter aortic valve replacement (TAVR) is associated with several conduction abnormalities and a need for pacemaker placement. The study aim was to describe all electrocardiographic (ECG) changes seen after TAVR, to compare such changes between transapical (TA) and transfemoral (TF) patient cohorts, and to assess their impact on postoperative outcomes. METHODS: Between March 2009 and July 2014, a total of 286 consecutive patients underwent TAVR at the present authors' institution. Perio...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Valve-Sparing Aortic Root Repair Compared to Composite Aortic Root Replacement: A Systematic Review and Meta-Analysis.
Authors: Harky A, Fok M, Froghi S, Bilal H, Bashir M Abstract BACKGROUND: Aortic root aneurysms represent a significant risk of morbidity and mortality. Composite root replacement is the preferred practice for repair, although recently valve-sparing replacement has become a popular alternative. The study aim was to identify comparative studies that simultaneously analyzed composite root and valve-sparing root replacement outcomes. METHODS: A systematic review of the current literature was performed through four major databases, from inception until 2016. All comparative studies of valve-sparing versus composite...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Long-Term Results after Modified Bentall Operation in 200 Patients.
Authors: Katselis C, Samanidis G, Papasotiriou A, Kriaras I, Antoniou T, Khoury M, Michalis A, Perreas K Abstract BACKGROUND: Composite graft replacement of the aortic root is the treatment of choice for an array of aortic root pathologies, such as annuloaortic ectasia, Marfan syndrome and acute or chronic aortic dissection type A. In this retrospective study of the authors' aortic surgery database, an exploration was made of factors related to early and long-term morbidity and mortality of patients who underwent this procedure. METHODS: Between 2000 and 2009, a total of 200 consecutive patients (male:female ra...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Cardioembolic Stroke from an Atrial Myxoma in a Pediatric Patient: A Case Report and Review of the Literature.
Authors: Aldajani AA, Mudhry MA, Mir A, Albaradie RS Abstract Cardioembolic stroke is an uncommon phenomenon in pediatric patients. Although the heart is the usual source of the condition, cardiac myxomas are still considered to be a rare cause in children. The case is presented of a 13-year-old, right-handed Saudi boy who showed right-sided weakness for 30 h prior to hospital admission that involved the face, arm, and leg, with slurred speech. The patient had been discharged previously from a local hospital, without active management. An examination showed decreased strength on the right side, with hyperreflexia a...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Survival Advantage of MitraClip ® Over Medical Treatment in Patients with Mitral Regurgitation: A Meta-Analysis.
Survival Advantage of MitraClip® Over Medical Treatment in Patients with Mitral Regurgitation: A Meta-Analysis. J Heart Valve Dis. 2017 Nov;26(6):651-658 Authors: Benito-González T, Estévez-Loureiro R, Iglesias-Gárriz I, Gualis J, Pérez de Prado A, Garrote C, Swaans MJ, S Van der Heyden JA, Feldman T, Giannini C, Alonso D, Rodriguez-Santamarta M, Castaño M, Fernández-Vázquez F Abstract BACKGROUND: The MitraClip® system is a percutaneous treatment for mitral regurgitation (MR) that has shown promising results in patients who are inoperable or at h...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Long-Term Follow Up After Successful Percutaneous Balloon Mitral Valvuloplasty.
Authors: Rodrigues I, Branco L, Patrício L, Bernardes L, Abreu J, Cacela D, Galrinho A, Ferreira R Abstract BACKGROUND: Percutaneous balloon mitral valvuloplasty (PMV) is the cornerstone of rheumatic mitral stenosis treatment in suitable patients. Previous studies have reported low rates of technical failure and few major complications, with good long-term results after successful PMV. The study aim was to assess the very long-term outcome in patients after PMV performed at a single tertiary center. METHODS: Between 1991 and 2010, a total of 213 consecutive patients underwent PMV at the authors' center. ...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Prevalence and Doppler Echocardiographic Characteristics of Normally Functioning Mitral Prostheses with Mean Gradient ≥10 mmHg.
CONCLUSIONS: The study data suggested that a plurality of individuals with a mean transprosthetic mitral gradient ≥10 mmHg will be found to have a normally functioning prosthesis. Most of these patients will have a small EOAi, a reduced Cn, and a relatively increased CI. PMID: 30207117 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Characterization of Effective Orifice Areas of Mitral Prosthetic Heart Valves: An In-Vitro Study.
CONCLUSIONS: The present study has provided normal reference values of EOAs for several frequently used mitral prostheses. This information may be helpful for identifying and quantifying prosthetic valve dysfunction and prosthesis-patient mismatch. PMID: 30207118 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Mitral Valve Repair for Mitral Regurgitation with Congenital Anomalies of the Papillary Muscles.
CONCLUSIONS: Mitral valve repair using artificial chordae reconstruction combined with ring annuloplasty is effective for treating regurgitant parachute mitral valve in adults. PMID: 30207119 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Clinicopathological Spectrum of Mitral Valve Myxoma.
Authors: Aguilar C, Espinoza D, Segura P, Donet JA Abstract Cardiac myxomas are the most common primary tumors of the heart. Although these tumors have been reported in all cardiac chambers, myxomas arising from heart valves are extremely rare. Here, the details are described of a patient with mitral valve myxoma, and a review is provided of 99 cases reported in the literature. Mitral valve myxomas most often occur in middle-aged patients, with a slight female predominance. Most of the tumors arise in an isolated fashion on the atrial side of the anterior mitral valve leaflet. Embolic events were the most frequent ...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Frequency and Clinical Significance of Right Atrial Embryonic Remnants Involvement in Infective Endocarditis.
CONCLUSIONS: Although the prevalence of embryonic remnants involvement in IE is underestimated, it may carry an important embolic risk if undetected. As TTE demonstrated only a low sensitivity in the diagnosis of embryonic remnant involvement, TEE should be performed systematically and RAER involvement carefully sought. TEE is recommended in all patients with a high clinical suspicion of right-sided IE. Video 1: Mid-esophageal TEE view. Multiple vegetations attached onto the pacemaker leads (broken arrow) and on the Eustachian valve (solid arrow). Video 2: Mid-esophageal TEE view. A vegetation attached onto the tricuspid v...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Antiplatelet Therapy for Long-Term Management of Patients with Mechanical Aortic Prostheses.
CONCLUSIONS: Platelet-mediated thromboembolism following MAP installation can be treated with antiplatelet agents. The 16-year results of the present study suggested that antiplatelet agents can reduce thromboembolic events in patients with MAP. Strokes can be prevented in patients with MAP if treated with the correct antiplatelet agent, if the patient responds to the agent employed and is strictly compliant. PMID: 30207122 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Red Cell Distribution Width as a Prognostic Marker in Patients Undergoing Valve Surgery.
CONCLUSIONS: An elevated RDW is associated with a worse outcome following valve surgery. The predictive ability of the RDW, when assessed by the area under the ROC curve, improved the predictive ability of the EuroSCORE II calculator. PMID: 30207123 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Early Experience with the Latest-Generation Biological Prosthesis, the Trifecta ™ GT.
CONCLUSIONS: Based on experience with patients, the Trifecta GT demonstrated an excellent hemodynamic performance after implantation, which involved a simple and safe technique. Further long-term studies to determine the durability of the prosthesis are required. PMID: 30207124 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

MitraClip ® Implantation Under Cerebral Protection: A Case Report.
MitraClip® Implantation Under Cerebral Protection: A Case Report. J Heart Valve Dis. 2017 Nov;26(6):728-730 Authors: Pohl J, Luedike P, Alexander Jánosi R, Rassaf T Abstract MitraClip® implantation is commonly used in patients with severe mitral regurgitation (MR) and who are at high risk for surgical mitral valve repair. The occurrence of stroke or transient ischemic attack is a potential complication in patients undergoing MitraClip implantation, and incidences of up to 2.6% have been reported. Herein is reported the case of an 84-year-old woman with severe MR and a thin filamentous st...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Mitral Valve Malignant Primary Tumor as a Surgical Emergency: Case Report.
Authors: Gomez MD, Gomez-Sanchez M, Antonio Arias-Godinez J, Jimenez-Becerra S, Herrera-Alarcon V Abstract Malignant primary tumors of the heart are among the most unusual forms of cancer. Cardiac malignancy accounts for about 20% of all primary cardiac tumors, with most arising from the atria and less frequently the ventricles; very unusual locations include the great vessels and the cardiac valves. A rare case is presented of a young female that arrived at the authors' emergency room in pulmonary edema and circulatory collapse secondary to a true tumor of the mitral leaflets that caused severe mitral valve stenos...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

The Modified Ross Procedure with Prosthetic Graft Wrap Does Not Prevent Autograft Failure.
Authors: Wang A, Ganapathi AM, Wang A, Hughes GC Abstract The modified Ross procedure, which involves replacement of the aortic valve with a pulmonary autograft root supported within a Dacron tube graft, was developed with the goal of preventing late autograft dilatation and associated aortic insufficiency. The case is reported of an adult patient who had a bicuspid aortic valve (BAV), underwent a modified Ross procedure, and developed severe aortic insufficiency within one year and subsequently required reoperation for aortic valve replacement. While advances have been made to increase the success of the Ross proc...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Congenital Left Ventricular-Right Atrial Communication Gerbode-Type Defect.
Authors: Elsheshtawy M, Abdelghany M, Shani J, Moscovits M Abstract Adult congenital heart diseases present a unique challenge in assessing right-sided cardiac chambers, where pressures can be mistakenly calculated using standard echocardiographic formulae. A challenging case is presented of a combined inlet ventricular septal defect and ventriculo-atrial Gerbode defect. The diagnosis of such adult congenital heart diseases requires an in-depth understanding of cardiac pathophysiology and hemodynamics. Video 1: Transthoracic echocardiography. Apical four-chamber view, showing a large inlet VSD with bidirectional sh...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

The Perceval Sutureless Valve in Aortic Root Reoperation.
Authors: Isbir S, Arsan S, Ak K, Cobanoglu A Abstract The case is reported of a 62-year-old man with severe aortic regurgitation that was related to failed prior valve-sparing ascending aortic aneurysm repair, and who was successfully treated with a Perceval Sutureless valve. PMID: 30207129 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Sternal-Sparing Aortic Valve Replacement in a Patient with Osteogenesis Imperfecta: A Case Report.
Authors: Joshi P, Thakur S, Finn C, Sadlier P Abstract The case described here is the first reported case of successful isolated aortic valve replacement (AVR) via a right anterior thoracotomy (RAT) in a patient with osteogenesis imperfecta (OI). The most common reported complication in patients with OI undergoing AVR or other cardiac surgery is bleeding and sternal complications. By using a RAT approach, it was possible to replace the aortic valve without major bleeding, transfusion, or sternal complications. PMID: 30207130 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Association of Change in Patient-Reported Health Status after Transcatheter Aortic Valve Replacement, and Postoperative Outcomes.
Authors: Kofi Okoh A, Kang N, Chauhan D, Haik N, Hanos D, Cohen M, Chen C, Haik B, Russo MJ Abstract BACKGROUND: The study aim was to investigate the relationship between postoperative morbidity after transcatheter aortic valve replacement (TAVR) and short-term patient-reported health status, using the Kansas City Cardiomyopathy Questionnaire (KCCQ). METHODS: The association between 30-day post-procedure changes in patient-reported heath status and post-TAVR outcomes was examined. Patients were stratified into three groups based on observed changes in KCCQ-Overall scores (OS): Group A, increase in KCCQ-OS ≥1...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Impact of Heart Rate on Flow Measurements in Aortic Regurgitation.
Authors: Lidén M, Wodecki M, Thunberg P, Rask P Abstract BACKGROUND: Flow measurements using cardiac magnetic resonance imaging (CMRI) enable quantification of the stroke volume, regurgitant volume (RV) and regurgitant fraction (RF) in patients with aortic regurgitation (AR). These variables are used to assess the severity of the valve disease and for the timing of surgery. The aim of the study was to investigate the impact of an increased heart rate on measurement of the RV and RF in patients with AR. METHODS: Among 13 patients with known moderate or severe AR, regurgitant flow measurements, using phase...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Incremental Value of Transesophageal Echocardiography Integrated with Transthoracic Echocardiography in the Assessment of Aortic Stenosis Severity.
CONCLUSIONS: TEE integrated with TTE may improve the detection of severe AS, particularly in patients with moderate AS criteria assessed by TTE, but with a DVI ratio ≤0.24. PMID: 29762919 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Outcomes of a New-Generation Stentless Aortic Valve: A Single-Center Experience with 251 Consecutive Implants.
CONCLUSIONS: The study results confirmed the favourable hemodynamic behavior, low risk of implantation and acceptable durability of the pericardial stentless SPF aortic prosthesis. The data also endorsed use of the SPF as an aortic valve substitute, even in a young and active population, and particularly in the presence of a small aortic annulus. The accuracy of implantation remains a crucial factor for durability and subsequent satisfactory hemodynamic performance. A longer follow up would provide further information with regards to complications and durability of the SPF prosthesis. PMID: 29762920 [PubMed - in proces...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Long-Term (up to 21 Years) Follow Up after Biological and Mechanical Aortic Valve Replacement in Younger Patients.
Authors: Tsvelodub S, Pieper B, Stock S, Sievers HH, Richardt D Abstract BACKGROUND: Despite the limited durability of biological aortic valves, increasing numbers of younger patients are choosing to receive them, due mainly to the lack of a need for permanent anticoagulation. Few data exist, however, regarding the outcomes of valve replacement in patients aged
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Redo Scoring for Prediction of Success of Redo-Percutaneous Balloon Mitral Valvuloplasty in Patients with Mitral Restenosis.
CONCLUSIONS: The described scoring system was significantly more predictive than the Wilkins score, and was particularly valuable in predicting outcome in patients with a prior PBMV. It may serve as a satisfactory scoring system for correctly selecting patients with mitral restenosis for PBMV. PMID: 29762922 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Intraoperative Transesophageal Echocardiography for Surgical Repair of Degenerative Mitral Regurgitation.
Authors: Pisano C, Calia C, Ricasoli A, Fabio Triolo O, Argano V Abstract BACKGROUND: Segmental analysis of diseased mitral valves is important to predict a successful surgical valve repair. An assessment was made of the comparative accuracy of intraoperative three-dimensional (3D) and two-dimensional (2D) transesophageal echocardiography (TEE) in the evaluation of mitral valve lesions when compared with intraoperative surgical segmental analysis. METHODS: A total of 42 consecutive patients (12 females, 30 males; mean age 70.5 ± 14 years) with severe mitral valve regurgitation due to degenerative disease...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Early Improvement in Mitral Regurgitation after Cardiac Resynchronization Therapy in Cardiomyopathy Patients.
Authors: Sadeghian H, Lotfi-Tokaldany M, Montazeri M, Kazemi Saeed A, Sahebjam M, Sardari A, Ejmalian G Abstract BACKGROUND: The study aim was to investigate factors affecting the improvement of mitral regurgitation (MR) severity within 48 hours after cardiac resynchronization therapy (CRT) in patients with cardiomyopathy. METHODS: Sixty-nine cardiomyopathy patients (48 males, 21 females; mean age 59.12 ± 9.66 years) in NYHA functional class ≥III, with left ventricular ejection fraction (LVEF) ≤35%, and QRS duration>120 ms, with MR ≥moderate, were included in the study. Conventional echocardi...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Association Between Myxomatous Mitral Valve Disease and Skeletal Back Abnormalities.
Authors: Movahed A, Majdalany D, Gillinov M, Schiavone W Abstract BACKGROUND: Myxomatous mitral valve disease (MMVD) is one of the most prevalent valvular heart diseases, while back pain, neck pain and upper-extremity numbness are some of the most common complaints in outpatient settings. Decreased thoracic kyphosis (straight back) is a known cause of hastening back or neck problems, radiculopathy, or even myelopathy. The study aim was to examine the relationship between MMVD, straight back, and the need for cervical fusion. METHODS: In this single-center retrospective study, patients who underwent mitral valve...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research