Aortic Valve Prolapse and Aortic Regurgitation During Long-Term Follow Up in Children with Ventricular Septal Defect.
CONCLUSIONS: Frequent (six-month) echocardiographic evaluation in patients with perimembraneous or muscular outlet VSD after AVP and AR development may be useful. In addition, surgical intervention in patients with perimembraneous or muscular outlet VSD, AVP and mild AR may prevent the worsening of AR. PMID: 30207110 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Electrocardiographic Correlates of Myocardial Injury After Transcatheter Aortic Valve Replacement.
Authors: Worku B, de Biasi A, Horowitz J, Kampaktsis P, Elmously A, Minutello R, Wong SC, Salemi A Abstract BACKGROUND: Transcatheter aortic valve replacement (TAVR) is associated with several conduction abnormalities and a need for pacemaker placement. The study aim was to describe all electrocardiographic (ECG) changes seen after TAVR, to compare such changes between transapical (TA) and transfemoral (TF) patient cohorts, and to assess their impact on postoperative outcomes. METHODS: Between March 2009 and July 2014, a total of 286 consecutive patients underwent TAVR at the present authors' institution. Perio...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Valve-Sparing Aortic Root Repair Compared to Composite Aortic Root Replacement: A Systematic Review and Meta-Analysis.
Authors: Harky A, Fok M, Froghi S, Bilal H, Bashir M Abstract BACKGROUND: Aortic root aneurysms represent a significant risk of morbidity and mortality. Composite root replacement is the preferred practice for repair, although recently valve-sparing replacement has become a popular alternative. The study aim was to identify comparative studies that simultaneously analyzed composite root and valve-sparing root replacement outcomes. METHODS: A systematic review of the current literature was performed through four major databases, from inception until 2016. All comparative studies of valve-sparing versus composite...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Long-Term Results after Modified Bentall Operation in 200 Patients.
Authors: Katselis C, Samanidis G, Papasotiriou A, Kriaras I, Antoniou T, Khoury M, Michalis A, Perreas K Abstract BACKGROUND: Composite graft replacement of the aortic root is the treatment of choice for an array of aortic root pathologies, such as annuloaortic ectasia, Marfan syndrome and acute or chronic aortic dissection type A. In this retrospective study of the authors' aortic surgery database, an exploration was made of factors related to early and long-term morbidity and mortality of patients who underwent this procedure. METHODS: Between 2000 and 2009, a total of 200 consecutive patients (male:female ra...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Cardioembolic Stroke from an Atrial Myxoma in a Pediatric Patient: A Case Report and Review of the Literature.
Authors: Aldajani AA, Mudhry MA, Mir A, Albaradie RS Abstract Cardioembolic stroke is an uncommon phenomenon in pediatric patients. Although the heart is the usual source of the condition, cardiac myxomas are still considered to be a rare cause in children. The case is presented of a 13-year-old, right-handed Saudi boy who showed right-sided weakness for 30 h prior to hospital admission that involved the face, arm, and leg, with slurred speech. The patient had been discharged previously from a local hospital, without active management. An examination showed decreased strength on the right side, with hyperreflexia a...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Survival Advantage of MitraClip ® Over Medical Treatment in Patients with Mitral Regurgitation: A Meta-Analysis.
Survival Advantage of MitraClip® Over Medical Treatment in Patients with Mitral Regurgitation: A Meta-Analysis. J Heart Valve Dis. 2017 Nov;26(6):651-658 Authors: Benito-González T, Estévez-Loureiro R, Iglesias-Gárriz I, Gualis J, Pérez de Prado A, Garrote C, Swaans MJ, S Van der Heyden JA, Feldman T, Giannini C, Alonso D, Rodriguez-Santamarta M, Castaño M, Fernández-Vázquez F Abstract BACKGROUND: The MitraClip® system is a percutaneous treatment for mitral regurgitation (MR) that has shown promising results in patients who are inoperable or at h...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Long-Term Follow Up After Successful Percutaneous Balloon Mitral Valvuloplasty.
Authors: Rodrigues I, Branco L, Patrício L, Bernardes L, Abreu J, Cacela D, Galrinho A, Ferreira R Abstract BACKGROUND: Percutaneous balloon mitral valvuloplasty (PMV) is the cornerstone of rheumatic mitral stenosis treatment in suitable patients. Previous studies have reported low rates of technical failure and few major complications, with good long-term results after successful PMV. The study aim was to assess the very long-term outcome in patients after PMV performed at a single tertiary center. METHODS: Between 1991 and 2010, a total of 213 consecutive patients underwent PMV at the authors' center. ...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Prevalence and Doppler Echocardiographic Characteristics of Normally Functioning Mitral Prostheses with Mean Gradient ≥10 mmHg.
CONCLUSIONS: The study data suggested that a plurality of individuals with a mean transprosthetic mitral gradient ≥10 mmHg will be found to have a normally functioning prosthesis. Most of these patients will have a small EOAi, a reduced Cn, and a relatively increased CI. PMID: 30207117 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Characterization of Effective Orifice Areas of Mitral Prosthetic Heart Valves: An In-Vitro Study.
CONCLUSIONS: The present study has provided normal reference values of EOAs for several frequently used mitral prostheses. This information may be helpful for identifying and quantifying prosthetic valve dysfunction and prosthesis-patient mismatch. PMID: 30207118 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Mitral Valve Repair for Mitral Regurgitation with Congenital Anomalies of the Papillary Muscles.
CONCLUSIONS: Mitral valve repair using artificial chordae reconstruction combined with ring annuloplasty is effective for treating regurgitant parachute mitral valve in adults. PMID: 30207119 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Clinicopathological Spectrum of Mitral Valve Myxoma.
Authors: Aguilar C, Espinoza D, Segura P, Donet JA Abstract Cardiac myxomas are the most common primary tumors of the heart. Although these tumors have been reported in all cardiac chambers, myxomas arising from heart valves are extremely rare. Here, the details are described of a patient with mitral valve myxoma, and a review is provided of 99 cases reported in the literature. Mitral valve myxomas most often occur in middle-aged patients, with a slight female predominance. Most of the tumors arise in an isolated fashion on the atrial side of the anterior mitral valve leaflet. Embolic events were the most frequent ...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Frequency and Clinical Significance of Right Atrial Embryonic Remnants Involvement in Infective Endocarditis.
CONCLUSIONS: Although the prevalence of embryonic remnants involvement in IE is underestimated, it may carry an important embolic risk if undetected. As TTE demonstrated only a low sensitivity in the diagnosis of embryonic remnant involvement, TEE should be performed systematically and RAER involvement carefully sought. TEE is recommended in all patients with a high clinical suspicion of right-sided IE. Video 1: Mid-esophageal TEE view. Multiple vegetations attached onto the pacemaker leads (broken arrow) and on the Eustachian valve (solid arrow). Video 2: Mid-esophageal TEE view. A vegetation attached onto the tricuspid v...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Antiplatelet Therapy for Long-Term Management of Patients with Mechanical Aortic Prostheses.
CONCLUSIONS: Platelet-mediated thromboembolism following MAP installation can be treated with antiplatelet agents. The 16-year results of the present study suggested that antiplatelet agents can reduce thromboembolic events in patients with MAP. Strokes can be prevented in patients with MAP if treated with the correct antiplatelet agent, if the patient responds to the agent employed and is strictly compliant. PMID: 30207122 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Red Cell Distribution Width as a Prognostic Marker in Patients Undergoing Valve Surgery.
CONCLUSIONS: An elevated RDW is associated with a worse outcome following valve surgery. The predictive ability of the RDW, when assessed by the area under the ROC curve, improved the predictive ability of the EuroSCORE II calculator. PMID: 30207123 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Early Experience with the Latest-Generation Biological Prosthesis, the Trifecta ™ GT.
CONCLUSIONS: Based on experience with patients, the Trifecta GT demonstrated an excellent hemodynamic performance after implantation, which involved a simple and safe technique. Further long-term studies to determine the durability of the prosthesis are required. PMID: 30207124 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

MitraClip ® Implantation Under Cerebral Protection: A Case Report.
MitraClip® Implantation Under Cerebral Protection: A Case Report. J Heart Valve Dis. 2017 Nov;26(6):728-730 Authors: Pohl J, Luedike P, Alexander Jánosi R, Rassaf T Abstract MitraClip® implantation is commonly used in patients with severe mitral regurgitation (MR) and who are at high risk for surgical mitral valve repair. The occurrence of stroke or transient ischemic attack is a potential complication in patients undergoing MitraClip implantation, and incidences of up to 2.6% have been reported. Herein is reported the case of an 84-year-old woman with severe MR and a thin filamentous st...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Mitral Valve Malignant Primary Tumor as a Surgical Emergency: Case Report.
Authors: Gomez MD, Gomez-Sanchez M, Antonio Arias-Godinez J, Jimenez-Becerra S, Herrera-Alarcon V Abstract Malignant primary tumors of the heart are among the most unusual forms of cancer. Cardiac malignancy accounts for about 20% of all primary cardiac tumors, with most arising from the atria and less frequently the ventricles; very unusual locations include the great vessels and the cardiac valves. A rare case is presented of a young female that arrived at the authors' emergency room in pulmonary edema and circulatory collapse secondary to a true tumor of the mitral leaflets that caused severe mitral valve stenos...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

The Modified Ross Procedure with Prosthetic Graft Wrap Does Not Prevent Autograft Failure.
Authors: Wang A, Ganapathi AM, Wang A, Hughes GC Abstract The modified Ross procedure, which involves replacement of the aortic valve with a pulmonary autograft root supported within a Dacron tube graft, was developed with the goal of preventing late autograft dilatation and associated aortic insufficiency. The case is reported of an adult patient who had a bicuspid aortic valve (BAV), underwent a modified Ross procedure, and developed severe aortic insufficiency within one year and subsequently required reoperation for aortic valve replacement. While advances have been made to increase the success of the Ross proc...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Congenital Left Ventricular-Right Atrial Communication Gerbode-Type Defect.
Authors: Elsheshtawy M, Abdelghany M, Shani J, Moscovits M Abstract Adult congenital heart diseases present a unique challenge in assessing right-sided cardiac chambers, where pressures can be mistakenly calculated using standard echocardiographic formulae. A challenging case is presented of a combined inlet ventricular septal defect and ventriculo-atrial Gerbode defect. The diagnosis of such adult congenital heart diseases requires an in-depth understanding of cardiac pathophysiology and hemodynamics. Video 1: Transthoracic echocardiography. Apical four-chamber view, showing a large inlet VSD with bidirectional sh...
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

The Perceval Sutureless Valve in Aortic Root Reoperation.
Authors: Isbir S, Arsan S, Ak K, Cobanoglu A Abstract The case is reported of a 62-year-old man with severe aortic regurgitation that was related to failed prior valve-sparing ascending aortic aneurysm repair, and who was successfully treated with a Perceval Sutureless valve. PMID: 30207129 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Sternal-Sparing Aortic Valve Replacement in a Patient with Osteogenesis Imperfecta: A Case Report.
Authors: Joshi P, Thakur S, Finn C, Sadlier P Abstract The case described here is the first reported case of successful isolated aortic valve replacement (AVR) via a right anterior thoracotomy (RAT) in a patient with osteogenesis imperfecta (OI). The most common reported complication in patients with OI undergoing AVR or other cardiac surgery is bleeding and sternal complications. By using a RAT approach, it was possible to replace the aortic valve without major bleeding, transfusion, or sternal complications. PMID: 30207130 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Association of Change in Patient-Reported Health Status after Transcatheter Aortic Valve Replacement, and Postoperative Outcomes.
Authors: Kofi Okoh A, Kang N, Chauhan D, Haik N, Hanos D, Cohen M, Chen C, Haik B, Russo MJ Abstract BACKGROUND: The study aim was to investigate the relationship between postoperative morbidity after transcatheter aortic valve replacement (TAVR) and short-term patient-reported health status, using the Kansas City Cardiomyopathy Questionnaire (KCCQ). METHODS: The association between 30-day post-procedure changes in patient-reported heath status and post-TAVR outcomes was examined. Patients were stratified into three groups based on observed changes in KCCQ-Overall scores (OS): Group A, increase in KCCQ-OS ≥1...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Impact of Heart Rate on Flow Measurements in Aortic Regurgitation.
Authors: Lidén M, Wodecki M, Thunberg P, Rask P Abstract BACKGROUND: Flow measurements using cardiac magnetic resonance imaging (CMRI) enable quantification of the stroke volume, regurgitant volume (RV) and regurgitant fraction (RF) in patients with aortic regurgitation (AR). These variables are used to assess the severity of the valve disease and for the timing of surgery. The aim of the study was to investigate the impact of an increased heart rate on measurement of the RV and RF in patients with AR. METHODS: Among 13 patients with known moderate or severe AR, regurgitant flow measurements, using phase...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Incremental Value of Transesophageal Echocardiography Integrated with Transthoracic Echocardiography in the Assessment of Aortic Stenosis Severity.
CONCLUSIONS: TEE integrated with TTE may improve the detection of severe AS, particularly in patients with moderate AS criteria assessed by TTE, but with a DVI ratio ≤0.24. PMID: 29762919 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Outcomes of a New-Generation Stentless Aortic Valve: A Single-Center Experience with 251 Consecutive Implants.
CONCLUSIONS: The study results confirmed the favourable hemodynamic behavior, low risk of implantation and acceptable durability of the pericardial stentless SPF aortic prosthesis. The data also endorsed use of the SPF as an aortic valve substitute, even in a young and active population, and particularly in the presence of a small aortic annulus. The accuracy of implantation remains a crucial factor for durability and subsequent satisfactory hemodynamic performance. A longer follow up would provide further information with regards to complications and durability of the SPF prosthesis. PMID: 29762920 [PubMed - in proces...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Long-Term (up to 21 Years) Follow Up after Biological and Mechanical Aortic Valve Replacement in Younger Patients.
Authors: Tsvelodub S, Pieper B, Stock S, Sievers HH, Richardt D Abstract BACKGROUND: Despite the limited durability of biological aortic valves, increasing numbers of younger patients are choosing to receive them, due mainly to the lack of a need for permanent anticoagulation. Few data exist, however, regarding the outcomes of valve replacement in patients aged
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Redo Scoring for Prediction of Success of Redo-Percutaneous Balloon Mitral Valvuloplasty in Patients with Mitral Restenosis.
CONCLUSIONS: The described scoring system was significantly more predictive than the Wilkins score, and was particularly valuable in predicting outcome in patients with a prior PBMV. It may serve as a satisfactory scoring system for correctly selecting patients with mitral restenosis for PBMV. PMID: 29762922 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Intraoperative Transesophageal Echocardiography for Surgical Repair of Degenerative Mitral Regurgitation.
Authors: Pisano C, Calia C, Ricasoli A, Fabio Triolo O, Argano V Abstract BACKGROUND: Segmental analysis of diseased mitral valves is important to predict a successful surgical valve repair. An assessment was made of the comparative accuracy of intraoperative three-dimensional (3D) and two-dimensional (2D) transesophageal echocardiography (TEE) in the evaluation of mitral valve lesions when compared with intraoperative surgical segmental analysis. METHODS: A total of 42 consecutive patients (12 females, 30 males; mean age 70.5 ± 14 years) with severe mitral valve regurgitation due to degenerative disease...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Early Improvement in Mitral Regurgitation after Cardiac Resynchronization Therapy in Cardiomyopathy Patients.
Authors: Sadeghian H, Lotfi-Tokaldany M, Montazeri M, Kazemi Saeed A, Sahebjam M, Sardari A, Ejmalian G Abstract BACKGROUND: The study aim was to investigate factors affecting the improvement of mitral regurgitation (MR) severity within 48 hours after cardiac resynchronization therapy (CRT) in patients with cardiomyopathy. METHODS: Sixty-nine cardiomyopathy patients (48 males, 21 females; mean age 59.12 ± 9.66 years) in NYHA functional class ≥III, with left ventricular ejection fraction (LVEF) ≤35%, and QRS duration>120 ms, with MR ≥moderate, were included in the study. Conventional echocardi...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Association Between Myxomatous Mitral Valve Disease and Skeletal Back Abnormalities.
Authors: Movahed A, Majdalany D, Gillinov M, Schiavone W Abstract BACKGROUND: Myxomatous mitral valve disease (MMVD) is one of the most prevalent valvular heart diseases, while back pain, neck pain and upper-extremity numbness are some of the most common complaints in outpatient settings. Decreased thoracic kyphosis (straight back) is a known cause of hastening back or neck problems, radiculopathy, or even myelopathy. The study aim was to examine the relationship between MMVD, straight back, and the need for cervical fusion. METHODS: In this single-center retrospective study, patients who underwent mitral valve...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Genetic Complexity of Mitral Valve Prolapse Revealed by Clinical and Genetic Evaluation of a Large Family.
CONCLUSIONS: While a contributory role for PTPRJ and FLYWCH1 in this family cannot be excluded, the study results underscored the difficulties involved in uncovering the genomic contribution to MVP, even in apparently Mendelian families. PMID: 29762926 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Isolated Pulmonary Valve Fungal Endocarditis with Candida parapsilosis: Management Considerations of a Rare Case.
Authors: Guragai N, Rampal U, Vasudev R, Shah D, Patel H, Salamera J, Pullatt R, Shamoon F Abstract Pulmonary valve infections without the involvement of other valves account for only 1.5- 2% of all infective endocarditis cases. Isolated pulmonary valve endocarditis due to fungus is extremely rare. The case is presented of a 36-year-old male who was found to have isolated pulmonary valve endocarditis caused by a very rare organism, Candida parapsilosis, and that was solely managed with medical therapy. The patient was evaluated for three weeks of lowgrade fever, generalized rash and fatigue, and found to have C. pa...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Early Thrombosis of a Mitral Annuloplasty Ring in a Patient with MTHFR and Factor V Leiden Mutations.
Authors: Cerşit S, Bayam E, Gündüz S, Özkan M Abstract Mitral annuloplasty ring thrombosis is an extremely infrequent pathology, for which no evidence-based antithrombotic management has yet been described. Herein is presented a case of heterozygous Factor V Leiden (FVL) and hyperhomocysteinemia with homozygous methylenetetrahydrofolate reductase (MTHFR) mutations that caused early thrombosis of the mitral annuloplasty ring. The clinical management and antithrombotic treatment of the patient, and the implications of hyperhomocysteinemia, are discussed. Video 1: Mobile 9-mm thrombus of mitral annulop...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Trileaflet Mitral Valve Treated with the MitraClip ® System.
Trileaflet Mitral Valve Treated with the MitraClip® System. J Heart Valve Dis. 2017 Sep;26(5):589-591 Authors: Rodríguez-Santamarta M, Estévez-Loureiro R, Benito-González T, Gualis J, Garrote C, Pérez de Prado A, Fernández-Vázquez F Abstract A 79-year-old woman with a history of ischemic dilated cardiomyopathy, severely depressed left ventricular ejection fraction and significant mitral regurgitation (MR) was admitted to the authors´ institution for percutaneous mitral valve repair. Transesophageal echocardiography (TEE) revealed the presence of a pos...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Cusp Tear of Trifecta ™ Aortic Bioprosthesis Resulting in Acute Heart Failure.
Cusp Tear of Trifecta™ Aortic Bioprosthesis Resulting in Acute Heart Failure. J Heart Valve Dis. 2017 Sep;26(5):592-594 Authors: Schaefer AK, Kocher A, Laufer G, Wiedemann D Abstract Herein is presented the case of an 83-year-old male patient in cardiogenic shock with acute aortic regurgitation that occurred six years after aortic valve replacement (AVR) with a 23 mm Trifecta™ valve. Prosthesis endocarditis was initially suspected because of a floating structure attached to the aortic valve that was visible on echocardiography. Emergency redo-AVR surgery was performed, but no signs of endocardit...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

MitraClip Technique Five Years after Alfieri Stitch Mitral Valve Repair.
Authors: Tonchev IR, Turyan A, Beeri R, Shuvy M Abstract The case is described of a successful MitraClip procedure performed on an 88-year-old patient with severe mitral regurgitation (MR), five years after she had undergone mitral valve repair using the Alfieri surgical procedure. It is suggested that the MitraClip procedure is an option in patients with severe MR persisting after the Alfieri procedure. Video 1: Transesophageal echocardiography before the MitraClip procedure. Severe mitral regurgitation with preserved left ventricular systolic function. The main regurgitant jet originates from the medial commissur...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Pulmonary Hypertension as a Possible Cause of Paradoxical Low-Flow, Low-Gradient Aortic Stenosis.
Authors: Watanabe Y, Higashi H, Inoue K, Aono J, Okura T, Higaki J, Ikeda S Abstract Paradoxical low-flow, low-gradient aortic stenosis (LFLG AS) is recognized as a subtype of aortic stenosis. A small left ventricular (LV) cavity with marked LV concentric remodeling leads to a reduced stroke volume in this condition. The case is reported of a paradoxical LFLG AS patient who was undergoing treatment for pulmonary hypertension (PH) and interstitial pneumonia associated with scleroderma. Echocardiography demonstrated enlargement of the right ventricle and a diminished LV cavity. Moreover, the aortic valve opening was ...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Ross Procedure Following a Dislodged Transcatheter Aortic Valve Replacement.
Authors: Schnittman SR, Weiss AJ, Varghese R, Stelzer P Abstract A 36-year-old pregnant woman with a history of rheumatic heart disease and prior aortic valve replacement and mitral valve repair presented to an outside hospital with severe aortic stenosis. The patient had a cardiac arrest upon labor induction and underwent a transcatheter aortic valve replacement (TAVR), which dislodged two days later. Five months later, the patient underwent removal of the dislodged TAVR and a Ross procedure at the authors' institution. The patient was stable upon discharge, with minimal aortic and pulmonary regurgitation. To the ...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Rescue TAVI for Aortic Regurgitation after Left Ventricular Assist Device Implantation Following Preoperative Impella ® Support.
Rescue TAVI for Aortic Regurgitation after Left Ventricular Assist Device Implantation Following Preoperative Impella® Support. J Heart Valve Dis. 2017 Sep;26(5):603-605 Authors: M Herrmann FE, Wellmann P, von Dossow V, Massberg S, Hagl C, Schramm R, Pichlmaier M Abstract A patient presented with a decompensated cardiomyopathy requiring invasive hemodynamic support with an Impella® heart pump. Extracorporeal life support (ECLS) became necessary during the further course and the patient was bridged to left ventricular assist device (LVAD) implantation. Postoperatively, the patient did not improv...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Septic Shock, Meningoencephalitis and Multiple Pulmonary Emboli: Case Report of an Uncommon Clinical Presentation of Ventricular Septal Defect Acute Infective Endocarditis.
Authors: Varela Barca L, López-Menéndez J, Redondo Palacios A, Rodríguez-Roda Stuart J Abstract The case is reported of a 55 year-old woman, with a previously known congenital septal defect, who was admitted to the emergency department with a diagnosis of meningoencephalitis, septic shock, and rapid clinical deterioration. Echocardiography revealed a vegetation occupying the right-side heart. Endocarditis affectation of the septal defect, aortic and tricuspid valves was noted and blood cultures were positive for Staphylococcus aureus. Urgent surgical treatment was performed whereby the ventricu...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Bentall ’s Procedure in Pediatric Mixed Connective Tissue Disease Syndrome: Management of Pediatric Aortic Aneurysm - A Brief Review.
Bentall’s Procedure in Pediatric Mixed Connective Tissue Disease Syndrome: Management of Pediatric Aortic Aneurysm - A Brief Review. J Heart Valve Dis. 2017 Sep;26(5):610-612 Authors: Ramaprabhu K, Prakash O, Davidson N, Bhalero S, Radhakrishnan S, Coelho R Abstract Mixed connective tissue disease (MCTD) syndrome in children may lead to large aortic aneurysms, which in turn pose a difficult surgical problem. Valve-sparing root replacement is not always a viable option as the disease process invariably affects the aortic valve leaflets. Among pediatric patients, the Ross procedure is contraindicated on...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Endoaneurysmorrhaphy for a Giant Inferobasal Left Ventricular Aneurysm Restoring Mitral Function.
Authors: Ramadani B, Schurr P, Möhlenkamp S, Lichtenberg A Abstract Over the years, the surgery of ventricular postinfarction aneurysm has evolved from linear resection to endoaneurysmorrhaphy using a patch. Technically, several aims that include the restoration of ventricular shape and function, exclusion of dead space, minimization of the risk of thrombus formation and restoration of valve function are pursued. Herein is reported the case of a 58-year-old male with a giant inferobasal aneurysm involving the mitral valve apparatus who underwent successful endoaneurysmorrhaphy. Correct sizing of the patch prov...
Source: Journal of Heart Valve Disease - May 17, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Valvular Heart Disease Epidemics.
CONCLUSION: The present study results showed that VHD is a frequent occurrence and is increasingly prevalent with age, constituting up to one-fourth of all in-hospital admissions for cardiovascular disease. VHD is a growing public health problem that should be addressed with appropriate resources to improve research into its nature, diagnosis and treatment. PMID: 29505225 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - March 8, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Outcomes of Surgery for Severe Aortic Regurgitation with Systolic Left Ventricular Dysfunction.
Authors: Bruno P, Cammertoni F, Rosenhek R, Mazza A, Nesta M, Burzotta F, D'Amario D, Massetti M Abstract BACKGROUND: Management of patients with aortic regurgitation (AR) and severe impairment of left ventricular (LV) function characterized by an ejection fraction (EF) ≤35% is challenging. Conflicting results regarding perioperative and long-term survival of these patients have been reported. The study aim was to compare in-hospital outcomes and long-term survival of patients with AR and severe LV dysfunction versus moderate dysfunction (35%
Source: Journal of Heart Valve Disease - January 7, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Impact of Tricuspid Valve Regurgitation on Early Outcomes after Transcatheter Aortic Valve Replacement.
CONCLUSIONS: The severity of TR is a strong independent parameter predictive of death at 30 days. Therefore, parameters of RV function such as TR should be incorporated into predictive models for patients undergoing TAVR. PMID: 29302936 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - January 7, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Stress Analysis of Transcatheter Aortic Valve Leaflets Under Dynamic Loading: Effect of Reduced Tissue Thickness.
CONCLUSIONS: The study results indicated that, the smaller the leaflet thickness, the higher the maximum principal stress. Increased mechanical stress on TAV leaflets may lead to accelerated tissue degeneration. By using a thinner leaflet, TAV durability may not atch with that of surgical bioprostheses. PMID: 29302937 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - January 7, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Long-Term Results of Aortic Root Surgery in Marfan Syndrome Patients: A Single-Center Experience.
CONCLUSIONS: The Bentall and David operations are both associated with satisfactory long-term results in MFS patients. The low rate of valve prosthesis-related complications suggested that the Bentall operation would continue to be a standard surgical treatment. The reimplantation technique, adopted for less-dilated aortas, provides satisfactory freedom from reoperation. Careful attention should be paid to the reimplantation technique in patients affected by a serious familiar genetic phenotype. PMID: 29302938 [PubMed - in process] (Source: Journal of Heart Valve Disease)
Source: Journal of Heart Valve Disease - January 7, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Transcatheter Aortic Valve Implantation in High-Risk/Inoperable Patients: Repositionable versus Non-Repositionable Self-Expanding Valve.
In this study, 63% of patients in the CVS group and 82% in the ERS group were defined as HRI. One in-hospital death was documented after 30 days. With regards to the HRI cohort, no difference in rates of PM use were noted (ERS 20% versus CVS 20%; p>0.9999). ERS patients were characterized by a higher prevalence of peripheral vascular disease (PVD) (46% versus 21%; p
Source: Journal of Heart Valve Disease - January 7, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Determinants and Outcome of Decision Making Among Patients with Severe Aortic Stenosis.
Authors: Hussain AI, Auensen A, Brunborg C, Aakhus S, Fiane A, Pettersen KI, Gullestad L Abstract BACKGROUND: Aortic valve replacement (AVR) improves survival and quality of life in patients with severe aortic stenosis (AS), but despite clear indications for surgical treatment a significant proportion of patients do not undergo AVR. The study aim was to identify clinical variables associated with the decision to perform AVR, and to assess the prognostic effect of surgery versus medical treatment in patients with severe AS adjusted for significant confounders and effect modifiers. METHODS: A prospective observat...
Source: Journal of Heart Valve Disease - January 7, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Long-Term Outcomes in Patients Undergoing Consecutive Bioprosthetic Aortic Valve Replacement.
Authors: Haydock MD, Wilkes CF, Ramanathan T, Haydock DA Abstract BACKGROUND: Worldwide, there is increased use of bioprosthetic valves in the aortic position. Part of this increase has been patient-driven for quality of life reasons. More recently, bioprosthetic valves have been chosen by progressively younger patients, with a strategy of performing a valve-in-valve TAVI if the prosthesis should wear out. Thus, a review was undertaken of the present authors' experience with patients whose first two aortic valve replacements (AVRs) were with bioprosthetic valves. METHODS: Patients receiving consecutive bioprost...
Source: Journal of Heart Valve Disease - January 7, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research