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Condition: Septic Shock

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Total 242 results found since Jan 2013.

Approaches in Prehospital Sepsis Screening
Discussion In the United States, sepsis is one of the leading causes of death, which requires timely identification and proper treatment (CDC, 2019; Guerra et al., 2020; Polito et al., 2015). Based upon a review of literature conducted from 2014 to 2018, the primary investigators could locate five prehospital EMS screening tools to assist EMS providers in identifying at-risk sepsis patients. The researchers explored how the modified SIRS and qSOFA scoring systems were used in hospital settings in addition to these five prehospital EMS screening tools. The Bas 90-30-90, Guerra, PRESEP, PRESS, and Robson tools have ove...
Source: JEMS Operations - January 5, 2021 Category: Emergency Medicine Authors: JEMS Staff Tags: Exclusives Patient Care EMS EMT Paramedic Prehospital Sepsis Source Type: news

Fluid Response Evaluation in Sepsis Hypotension and Shock
Patients in septic shock routinely receive large volumes of intravenous fluids as part of their initial resuscitation. However, hypervolemia secondary to aggressive fluid administration is associated with increased morbidity and mortality including renal failure, respiratory failure, or death. Dynamic approaches to hemodynamic monitoring for fluid responsiveness (FR) including measurement of stroke volume (SV) following increased fluid volume through IV fluids during passive leg raise (PLR) may have a role in guiding resuscitative efforts, although the benefits in an emergency department or ICU setting are unclear.
Source: The Journal of Emergency Medicine - January 1, 2021 Category: Emergency Medicine Authors: Benjamin Robert Wagner, Zachary B. Lewis Tags: Abstract Source Type: research

Effect of VTILVOT variation rate on the assessment of fluid responsiveness in septic shock patients
This study aimed to assess the predictive value of velocity time integral (VTI) of the left ventricular outflow tract (LVOT) on volume expansion test (VET) as an indicator of volume responsiveness in septic shock patients. Septic shock patients undergoing mechanical ventilation were recruited. The hemodynamic parameters before and after VE were monitored by pulse indicated continuous cardiac output (PiCCO) and echocardiography. Heart rate, cardiac index (CI), mean arterial pressure (MAP), central venous pressure, stroke volume variation (SVV), CI and variation of pulse pressure (PPV), and the changes in cardiac parameters ...
Source: Medicine - November 20, 2020 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Dynamic Arterial Elastance During Experimental Endotoxic Septic Shock: A Potential Marker of Cardiovascular Efficiency
Dynamic arterial elastance (Eadyn), the ratio between pulse pressure variation (PPV) and stroke volume variation (SVV), has been suggested as a dynamic parameter relating pressure and flow. We aimed to determine the effects of endotoxic septic shock and hemodynamic resuscitation on Eadyn in an experimental study in 18 New Zealand rabbits. Animals received placebo (SHAM, n = 6) or intravenous lipopolysaccharide (E. Coli 055:B5, 1 mg⋅kg–1) with or without (EDX-R, n = 6; EDX, n = 6) hemodynamic resuscitation (fluid bolus of 20 ml⋅kg–1 and norepinephrine for restoring mean arterial pressure). Continuous arterial pressu...
Source: Frontiers in Physiology - October 1, 2020 Category: Physiology Source Type: research

Idarucizumab for dabigatran reversal in daily clinical practice: A case series
CONCLUSION Our first experiences with idarucizumab use in daily-care settings support a rapid and efficient decrease in the anticoagulant effect of dabigatran in emergency situations. Late re-occurrence of dabigatran effect was noted in a subset of patients with severe renal failure.
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Coagulation Source Type: research

Studying the Clinical Data of COVID Positive patients admitted to a tertiary care academic hospital
Conclusion: The most common presenting symptoms included fever, cough, and shortness of breath. Patients who required ICU admission at presentation had a worse prognosis. Those with greater severity of symptoms were mainly elderly patients among which the most common comorbidity was hypertention followed by cardiac disease.
Source: Journal of Emergencies, Trauma and Shock - June 9, 2020 Category: Emergency Medicine Authors: Julio Arrieta Sagar Galwankar Natalia Lattanzio Darrel Ray Amit Agrawal Source Type: research

Respiratory Variations in Aortic Blood Flow to Predict Volume Responsiveness in Ventilated Children With Leukemia and Neutropenic Septic Shock*
Conclusions: Respiratory variation in velocity time integral of aortic blood flow and respiratory variation in peak velocity of aortic blood flow derived from transthoracic echocardiography showed only a fair reliability in predicting volume responsiveness in ventilated children with leukemia and neutropenic septic shock.
Source: Pediatric Critical Care Medicine - May 1, 2020 Category: Pediatrics Tags: Online Clinical Investigations Source Type: research

Fluid Response Evaluation in Sepsis Hypotension and Shock: A Randomized Clinical Trial.
Abstract BACKGROUND: Fluid and vasopressor management in septic shock remains controversial. In this randomized controlled trial, we evaluated the efficacy of dynamic measures (stroke volume change during passive leg raise) to guide resuscitation and improve patient outcome. RESEARCH QUESTION: Will resuscitation guided by dynamic assessments of fluid responsiveness in patients with septic shock improve patient outcomes? STUDY DESIGN: and Methods: Prospective, multicenter, randomized clinical trial at 13 hospitals in the United States and United Kingdom. Patients presented to Emergency Rooms with sepsis a...
Source: Chest - April 26, 2020 Category: Respiratory Medicine Authors: Douglas IS, Alapat PM, Corl KA, Exline MC, Forni LG, Holder AL, Kaufman DA, Khan A, Levy MM, Martin GS, Sahatjian JA, Seeley E, Self WH, Weingarten JA, Williams M, Hansell DM Tags: Chest Source Type: research

Efficacy of primary surgical versus medical intervention for treatment of left-sided infective endocarditis.
CONCLUSIONS: Compared with medical management, valve replacement surgery in patients with left-sided SA, SC, or EC IE appears to confer a survival advantage at 30 days and 1 year. PMID: 32315643 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - April 17, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Gatzoflias S, Beier M, Ning Y, Kossar A, Gailes M, Guaman K, Segall M, Vasireddi A, Wang C, Takeda K, Takayama H, Bapat V, Naka Y, Argenziano M, Smith C, Gordon R, Gutierrez J, Kurlansky P, George I Tags: Ann Thorac Surg Source Type: research

A Simple Risk Score to Predict Clavien-Dindo Grade IV and V Complications After Non-elective Cholecystectomy
ConclusionA simple risk-score model predicts severe complications in patients undergoing unplanned cholecystectomy for common indications encountered in an acute care surgery service and identifies high-risk patients.
Source: Journal of Gastrointestinal Surgery - February 5, 2020 Category: Surgery Source Type: research