Functional MRI: basic principles and emerging clinical applications for anaesthesiology and the neurological sciences
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 1, 2019 Category: Anesthesiology Tags: Book review Source Type: research

Atypical clinical presentation of variant Creutzfeldt–Jakob disease
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 1, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Air embolism during venous sheath replacement
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 1, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Rhabdomyolysis and muscle infarcts associated with intra-operative compression
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 1, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Intra-operative rhabdomyolysis during upper limb surgery
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 1, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Peri-operative role of continuous positive airway pressure in mitigating respiratory side effects associated with interscalene brachial plexus block: A proof-of-concept study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 1, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Effects of pre-operative recreational smoked cannabis use on opioid consumption following inflammatory bowel disease surgery: A historical cohort study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 1, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Can quantitative sensory tests predict failed back surgery?: A prospective cohort study
CONCLUSION The study indicates that assessment of altered central pain processing using current QST is unlikely to identify patients at risk of FBSS and is therefore unlikely to inform clinical decisions. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 1, 2019 Category: Anesthesiology Tags: Diagnostic and prediction Source Type: research

Pre-operative assessment of 30-day mortality risk after major surgery: the role of the quick sequential organ failure assessment: A retrospective observational study
This study investigated the relationship between pre-operative qSOFA scores and 30-day mortality after major surgery. It also evaluated the predictive value of qSOFA scores combined with the American Society of Anesthesiologists (ASA) physical status and Charlson comorbidity index (CCI). DESIGN A retrospective observational study. SETTING Single tertiary academic hospital. PATIENTS Medical records of patients who underwent major surgery (estimated blood loss>500 ml; surgery time>2 h) between January 2010 and December 2017 were examined. MAIN OUTCOME MEASURES The qSOFA score was measured within 24 h ...
Source: European Journal of Anaesthesiology - August 1, 2019 Category: Anesthesiology Tags: Diagnostic and prediction Source Type: research

Validation of 3-minute diagnostic interview for CAM-defined Delirium to detect postoperative delirium in the recovery room: A prospective diagnostic study
CONCLUSION In this diagnostic study, 3D-CAM showed strong performance for detection of POD in the recovery room. Due to the low training requirements, fast application and high sensitivity, it might be particularly appropriate for clinical staff with limited experience in the assessment of POD. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT02992717 (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 1, 2019 Category: Anesthesiology Tags: Diagnostic and prediction Source Type: research

Colour Doppler ultrasound after major cardiac surgery improves diagnostic accuracy of the pulmonary infection score in acute respiratory failure: A prospective observational study
CONCLUSION Compared with sCPIS, LUS-sCPIS improved diagnostic accuracy in the detection of postoperative pneumonia in patients with acute respiratory failure after cardiac surgery. It could be a useful bedside tool to guide pneumonia management. TRIAL REGISTRATION Clinicaltrials.gov identifier: NCT03279887. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 1, 2019 Category: Anesthesiology Tags: Diagnostic and prediction Source Type: research

Complex effects of continuous vasopressor infusion on fluid responsiveness during liver resection: A randomised controlled trial
CONCLUSION Continuous administration of phenylephrine increased fluid responsiveness during liver resection, suggesting complex effects of continuous vasopressor infusion involving changes in cardiac preload and afterload. TRIAL REGISTRATION UMIN000011024. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 1, 2019 Category: Anesthesiology Tags: Pharmacology Source Type: research

Propofol intravenous anaesthesia with desflurane compared with desflurane alone on postoperative liver function after living-donor liver transplantation: A randomised controlled trial
CONCLUSION Despite the simultaneous administration of propofol infusion in both donors and recipients, no improvement in laboratory or surgical outcome was observed after LDLT compared with patients who received desflurane anaesthesia alone. TRIAL REGISTRATION NCT02504138 at clinicaltrials.gov. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 1, 2019 Category: Anesthesiology Tags: Pharmacology Source Type: research

Effect of sevoflurane-based or propofol-based anaesthesia on the incidence of postoperative acute kidney injury: A retrospective propensity score-matched analysis
CONCLUSION In this retrospective study, no significant difference was found in the incidence of postoperative AKI after lung resection surgery between patients who received propofol-based TIVA and those who received sevoflurane-based inhalational anaesthesia. Considering the methodological limitation of this retrospective study, further studies are required to confirm these results. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 1, 2019 Category: Anesthesiology Tags: Pharmacology Source Type: research

Comparison of low and high positive end-expiratory pressure during low tidal volume ventilation in robotic gynaecological surgical patients using electrical impedance tomography: A randomised controlled trial
BACKGROUND The appropriate level of positive end-expiratory pressure (PEEP) during intra-operative mechanical ventilation remains unclear. OBJECTIVE The aim of this study was to investigate the effects of different levels of PEEP with low tidal volume (low-VT) ventilation in a steep Trendelenburg position (30°) and pneumoperitoneum on oxygenation, respiratory mechanics and ventilation distribution using electrical impedance tomography. DESIGN A randomised controlled trial. SETTING Single university secondary care centre, conducted from January 2017 to December 2017. PATIENTS Forty female patients, aged 20...
Source: European Journal of Anaesthesiology - August 1, 2019 Category: Anesthesiology Tags: Ventilation Source Type: research

Comparison of a simplified nasal continuous positive airways pressure device with nasal cannula in obese patients undergoing colonoscopy during deep sedation: A randomised clinical trial
BACKGROUND Continuous positive airways pressure (CPAP) with a CPAP machine and mask has been shown to be more effective at minimising hypoxaemia than other devices under deep sedation. However, the efficacy of a new and simple CPAP device for spontaneously breathing obese patients during colonoscopy is unknown. OBJECTIVE We hypothesised that oxygenation and ventilation in obese patients under deep sedation during colonoscopy using CPAP via a new nasal mask (SuperNO2VA) would be better than routine care with oxygen supplementation via a nasal cannula. DESIGN Randomised study. SETTING Single-centre, June 2017 to O...
Source: European Journal of Anaesthesiology - August 1, 2019 Category: Anesthesiology Tags: Ventilation Source Type: research

Effect of positive end-expiratory pressure on gastric insufflation during induction of anaesthesia when using pressure-controlled ventilation via a face mask: A randomised controlled trial
BACKGROUND Face mask ventilation (FMV) during induction of anaesthesia is associated with risk of gastric insufflation that may lead to gastric regurgitation and pulmonary aspiration. A continuous positive airway pressure (CPAP) has been shown to reduce gastric regurgitation. We therefore hypothesised that CPAP followed by FMV with positive end-expiratory pressure (PEEP) during induction of anaesthesia would reduce the risk of gastric insufflation. OBJECTIVE The primary aim was to compare the incidence of gastric insufflation during FMV with a fixed PEEP level or zero PEEP (ZEEP) after anaesthesia induction. A seconda...
Source: European Journal of Anaesthesiology - August 1, 2019 Category: Anesthesiology Tags: Ventilation Source Type: research

Cannabis hyperalgesia: A phenomenon underestimated in the peri-operative period?
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 1, 2019 Category: Anesthesiology Tags: Invited Commentary Source Type: research

Anaesthesia and orphan disease: Dubowitz syndrome
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 8, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

A possible treatment for propofol-induced neuroexcitation or propofol frenzy
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 8, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

The occurrence of myocardial injury after carotid endarterectomy: The result of routine troponin screening
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 8, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Management of neuraxial anaesthesia for intrapartum caesarean delivery based on the quality of epidural labour analgesia: A case series
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 8, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Pre-operative evaluation of microcirculation for the prediction of complications after cardiac surgery under extracorporeal circulation: Study protocol
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 8, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Diaphragmatic dysfunction following cardiac surgery: Observational study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 8, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Effect of pre-operative oral carbohydrate loading on recovery after day-case cholecystectomy: A randomised controlled trial
CONCLUSION Compared with overnight fasting, pre-operative carbohydrate loading did not significantly enhance peri-operative well being or recovery in patients undergoing day-case cholecystectomy. TRIAL REGISTRATION Clinicaltrials.gov Identifier: NCT03757208. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 8, 2019 Category: Anesthesiology Tags: Fluids Source Type: research

Effects of goal-directed crystalloid vs. colloid fluid therapy on microcirculation during free flap surgery: A randomised clinical trial
CONCLUSION Our results showed that when fluid management was guided by detailed haemodynamic assessment, more crystalloid than colloid was needed to maintain haemodynamic stability, but there was no difference between the effects of crystalloids and colloids on the microcirculation. TRIAL REGISTRATION ClinicalTrials.gov NCT03288051. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 8, 2019 Category: Anesthesiology Tags: Fluids Source Type: research

Tidal volume challenge to predict fluid responsiveness in the operating room: An observational study
CONCLUSION The changes in PPV and SVV obtained after VTC are reliable and comparable to the changes in CI and SVI obtained after EEOT performed at 8 ml kg−1 PBW in predicting fluid responsiveness in neurosurgical patients. TRIAL REGISTRATION ACTRN12618000351213. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 8, 2019 Category: Anesthesiology Tags: Fluids Source Type: research

The impact of a transversus abdominis plane block including clonidine vs. intrathecal morphine on nausea and vomiting after caesarean section: A randomised controlled trial
BACKGROUND Intrathecal morphine (ITM) is a widely used technique for postcaesarean section analgesia but entails a high risk of postoperative nausea and vomiting (PONV). The transversus abdominis plane (TAP) block is an alternative. OBJECTIVE We tested the hypothesis that a TAP block including clonidine reduces the incidence of PONV after caesarean section when compared with ITM. DESIGN A randomised, controlled, double-blinded study. SETTING Geneva University Hospitals, Switzerland, from October 2013 to February 2017. PATIENTS A total of 182 patients undergoing elective caesarean section were studied. Reasons...
Source: European Journal of Anaesthesiology - July 8, 2019 Category: Anesthesiology Tags: Postoperative nausea and vomiting Source Type: research

A serotonin transporter polymorphism is associated with postoperative nausea and vomiting: An observational study in two different patient cohorts
BACKGROUND Clinical risk factors for postoperative nausea and vomiting (PONV) are well described, whereas genetic findings are conflicting. OBJECTIVE The aim of this study was to investigate a possible association of genetic variants and nongenetic variables with the incidence and severity of PONV. DESIGN A prospective observational study in two independent and different patient cohorts. SETTING Two independent patient cohorts differing in surgical procedures were enrolled in two tertiary care hospitals between 2008 and 2016. PATIENTS Consecutive patients of European origin undergoing elective surgery in two ...
Source: European Journal of Anaesthesiology - July 8, 2019 Category: Anesthesiology Tags: Postoperative nausea and vomiting Source Type: research

Efficacy of acupressure on quality of recovery after surgery: Randomised controlled trial
CONCLUSION Two days of postoperative acupressure therapy (up to six treatments) did not significantly improve patient QoR, postoperative nausea and vomiting, pain score or opioid consumption. Acupressure, however, was associated with improved patient satisfaction. TRIAL REGISTRATION ClinicalTrials.gov, identifier: NCT02762435. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 8, 2019 Category: Anesthesiology Tags: Postoperative nausea and vomiting Source Type: research

Acupressure and quality of recovery
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 8, 2019 Category: Anesthesiology Tags: Invited commentary Source Type: research

Protocolised personalised peri-operative haemodynamic management
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 8, 2019 Category: Anesthesiology Tags: Editorial Source Type: research

Variation in medicines on anaesthesia carts in operating rooms
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 11, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

A clinical pathway developed on the principles of lean management improves hospitalisation capacity in outpatient hand surgery: A retrospective study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 11, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Mild to moderate degree of neck flexion improves sealing pressures without compromising ventilation with I-Gel in anaesthetised adults: A prospective observational study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 11, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Comparison of the acromio-axillosuprasternal notch index with five anatomical indices for the prediction of difficult laryngoscopy and intubation
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 11, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

New device and technique for lung deflation in bronchial blocker
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 11, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Assessment of cerebral and renal autoregulation using near-infrared spectroscopy under normal, hypovolaemic and postfluid resuscitation conditions in a swine model: An observational study
CONCLUSION Renal oxygenation is more pressure-dependent than pressure-tolerant cerebral oxygenation, and autoregulation is not robust. Renal oxygenation decreased four-fold compared with cerebral oxygenation during hypovolaemia and two-fold during isovolaemic anaemia. Thus, paradoxical responses are part of normal autoregulatory function and beneficial for maintaining stable oxygenation. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 11, 2019 Category: Anesthesiology Tags: Resuscitation Source Type: research

Initial end-tidal carbon dioxide as a predictive factor for return of spontaneous circulation in nonshockable out-of-hospital cardiac arrest patients: A retrospective observational study
CONCLUSION Patients with a nonshockable out-of-hospital cardiac arrest who presented with higher values of initial ETCO2 had an increased chance of sustained ROSC and survival. This finding could help decision making as regards continuation of resuscitation efforts. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 11, 2019 Category: Anesthesiology Tags: Resuscitation Source Type: research

Necessity to depict difficult neck anatomy for training of cricothyroidotomy: A pilot study evaluating two surgical devices on a new hybrid training model
CONCLUSION Participants had difficulties in performing cricothyroidotomy in obese models, but various and difficult anatomical situations must be expected in airway management and therefore must be taught. A new hybrid model combining porcine and synthetic materials offers the necessary conditions for the next step in training of surgical airway procedures. TRIAL REGISTRATION The study was performed without human tissue or living animals, and was therefore exempted from ethical review by the University of Ulm Ethical Committee, Germany (Chairperson Prof Dr C. Lenk) on 9 August 2018. Hence a protocol number was not att...
Source: European Journal of Anaesthesiology - June 11, 2019 Category: Anesthesiology Tags: Airway management Source Type: research

Ultrasound as a new tool in the assessment of airway difficulties: An observational study
CONCLUSION The prospective observational study confirms the relationship between ultrasound assessment of the anterior soft tissues of the neck and difficult laryngoscopy and DMV. DSHB and the other distances extend the available evidence, not only for difficult laryngoscopy but also for DMV. TRIAL REGISTRATION Clinicaltrials.gov. identified NCT03592758. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 11, 2019 Category: Anesthesiology Tags: Airway management Source Type: research

Effect of pretreatment with magnesium sulphate on the duration of intense and deep neuromuscular blockade with rocuronium: A randomised controlled trial
CONCLUSION Magnesium sulphate increased both the duration of intense NMB and the period of no response. The duration of deep NMB was similar in the magnesium sulphate group and saline group. TRIAL REGISTRATION ClinicalTrials.gov identifier: NCT02989272. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 11, 2019 Category: Anesthesiology Tags: Neuromuscular blocking agents Source Type: research

Efficacy of profound versus moderate neuromuscular blockade in enhancing postoperative recovery after laparoscopic donor nephrectomy: A randomised controlled trial
CONCLUSION Secondary analysis indicates that an adequately maintained profound neuromuscular block improves postoperative pain scores and quality of recovery. As the intention-to-treat analysis did not reveal a difference regarding the primary endpoint, future studies should pursue whether a thoroughly maintained profound NMB during laparoscopy improves relevant patient outcomes. TRIAL REGISTRATION ClinicalTrials.gov identifier: NCT02838134. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 11, 2019 Category: Anesthesiology Tags: Neuromuscular blocking agents Source Type: research

Deep neuromuscular blockade improves surgical conditions during gastric bypass surgery for morbid obesity: A randomised controlled trial
BACKGROUND There is a controversy in the literature whether deep compared with moderate neuromuscular block (NMB) improves surgical conditions for laparoscopic surgery. OBJECTIVES The primary outcome measure was to examine whether switching from moderate to deep NMB improves surgical conditions for laparoscopic surgery in the obese; secondary outcome measures were changes in intra-abdominal pressure, time required to perform the gastrojejunal anastomosis and peri-operative surgical complications. DESIGN A single-centre, randomised controlled study. Each patient was taken as their own control and examined twice: at ...
Source: European Journal of Anaesthesiology - June 11, 2019 Category: Anesthesiology Tags: Neuromuscular blocking agents Source Type: research

Resistance towards nondepolarising muscle relaxants: prolonged onset time: A systematic review
CONCLUSION A prolonged onset time should be suspected in patients with thermal injury and Duchenne's muscular dystrophy. Further, evidence supports a prolonged onset time in patients with infection, oculopharyngeal muscular dystrophy, congenital heart defects, kidney failure, liver cirrhosis treated with ulinastatin along with remifentanil or intravenous fluids administered prior to NDMR. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 11, 2019 Category: Anesthesiology Tags: Neuromuscular blocking agents Source Type: research

Medical training in anaesthesiology: Updated European requirements
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - June 11, 2019 Category: Anesthesiology Tags: Editorial Source Type: research

Recent Advances in Anesthesiology
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 2, 2019 Category: Anesthesiology Tags: Book review Source Type: research

Near-infrared spectroscopy: A measurement tool for ‘vegetables’?
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 2, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Near-infrared spectroscopy measures extinction of light by chromophores
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 2, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research

Reply to: ultrasound assessment of gastric emptying time after a standardised light breakfast in healthy children
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 2, 2019 Category: Anesthesiology Tags: Correspondence Source Type: research