Opioid-sparing effect of modified intercostal nerve block during single-port thoracoscopic lobectomy: A randomised controlled trial. Retraction
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 20, 2021 Category: Anesthesiology Tags: Retraction Source Type: research

Spinal injection techniques
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 20, 2021 Category: Anesthesiology Tags: Book review Source Type: research

Continuous remote monitoring to detect critical early warning scores after abdominal surgery: A prospective cohort study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 20, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

A simple equation for ideal body weight
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 20, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Concentrations of fentanyl before and after initiation of continuous venovenous haemodialysis in septic patients with acute kidney injury: A prospective observational study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 20, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Remote organ ischaemic preconditioning in human recipients suppresses systemic inflammation and prevents glycocalyx degradation in living-donor liver transplantation: A randomised controlled trial
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 20, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Reply to: very early creatinine changes and 30-day mortality after cardiac surgery
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 20, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Very early creatinine changes and 30-day mortality after cardiac surgery
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 20, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Peri-operative care of the cannabis user: practical considerations
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 20, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Vasopressor effects on venous return in septic patients: a review
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 20, 2021 Category: Anesthesiology Tags: Perioperative intensive care and care of the critically ill Source Type: research

Evaluation of glomerular filtration rate using iohexol plasma clearance in critically ill patients with augmented renal creatinine clearance: A single-centre retrospective study
CONCLUSION In the present study, we found that in patients with augmented renal creatinine clearance, half of the patients do not have hyperfiltration using iohexol clearance measurements. We observed an important bias between 6 h CrCl and GFRio with large LoA. In critically patients with ARC, 6 h CrCl does not reliably estimate GFR and 6 h CrCl nearly systematically overestimates renal function. Comparison of creatinine-based GFR estimations and GFRio show acceptable bias but wide LoA. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 20, 2021 Category: Anesthesiology Tags: Perioperative intensive care and care of the critically ill Source Type: research

An analysis of prehospital critical care events and management patterns from 97 539 emergency helicopter medical service missions: A retrospective registry-based study
CONCLUSION Prehospital exposure is distributed unevenly, and some physicians receive limited exposure to prehospital critical care. This seems to be associated with differences in practice patterns. Rare HEMS patient contacts may be associated with increased mortality. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 20, 2021 Category: Anesthesiology Tags: Perioperative intensive care and care of the critically ill Source Type: research

Effects of two stepwise lung recruitment strategies on respiratory function and haemodynamics in anaesthetised pigs: A randomised crossover study
BACKGROUND Lung recruitment manoeuvres and positive end-expiratory pressure (PEEP) can improve lung function during general anaesthesia. Different recruitment manoeuvre strategies have been described in large international trials: in the protective ventilation using high vs. low PEEP (PROVHILO) strategy, tidal volume (VT) was increased during volume-controlled ventilation; in the individualised peri-operative open-lung approach vs. standard protective ventilation in abdominal surgery (iPROVE) strategy, PEEP was increased during pressure-controlled ventilation. OBJECTIVES To compare the effects of the PROVHILO st...
Source: European Journal of Anaesthesiology - May 20, 2021 Category: Anesthesiology Tags: Perioperative intensive care and care of the critically ill Source Type: research

Hidden sources of fluids, sodium and potassium in stabilised Swedish ICU patients: A multicentre retrospective observational study
CONCLUSION Maintenance and drug fluids far exceeded resuscitative fluids in ICU patients beyond the resuscitative phase. This excess fluid intake, in conjunction with high urinary output and treatment for fluid offload in almost all patients, suggests that a large volume of the maintenance fluids given was unnecessary. TRIAL REGISTRATION ClinicalTrials.org NCT03972475 (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 20, 2021 Category: Anesthesiology Tags: Perioperative intensive care and care of the critically ill Source Type: research

Agreement between continuous noninvasive finger cuff-derived and invasive arterial blood pressure measurements: Effect of data sampling and data processing
CONCLUSION Data sampling and data processing substantially impact the results of comparative statistics in method comparison studies of continuous AP monitoring systems. Depending on the method used for data sampling and data processing, the performance of an AP test method may be considered clinically acceptable or unacceptable. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 20, 2021 Category: Anesthesiology Tags: Perioperative risk management Source Type: research

Clinical performance of a machine-learning algorithm to predict intra-operative hypotension with noninvasive arterial pressure waveforms: A cohort study
CONCLUSION This study demonstrated that the algorithm can be employed using continuous noninvasive ABP waveforms. This opens up the potential to predict and prevent hypotension in a larger patient population. TRIAL REGISTRATION Clinical trials registration number NCT03533205. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 20, 2021 Category: Anesthesiology Tags: Perioperative risk management Source Type: research

Expert consensus on peri-operative myocardial injury screening in noncardiac surgery: A literature review
Peri-operative myocardial injury, detected by dynamic and elevated cardiac troponin (cTn) concentrations, is a common complication of noncardiac surgery that is strongly associated with 30-day mortality. Although active screening for peri-operative myocardial injury has been suggested in recent guidelines, clinical implementation remains tentative due to a lack of examples on how to tackle such an interdisciplinary project at a local level. Moreover, consensus on which assay and cTn cut-off values should be used has not yet been reached, and guidance on whom to screen is lacking. In this article, we aim to summarise local ...
Source: European Journal of Anaesthesiology - May 20, 2021 Category: Anesthesiology Tags: Perioperative risk management Source Type: research

Pre-operative N-terminal pro-B-type natriuretic peptide for prediction of acute kidney injury after noncardiac surgery: A retrospective cohort study
BACKGROUND Acute kidney injury (AKI) is associated with poor outcomes after noncardiac surgery. Whether pre-operative N-terminal pro-B-type natriuretic peptide (NT-proBNP) predicts AKI after noncardiac surgery is unclear. OBJECTIVE To investigate the predictive role of pre-operative NT-proBNP on postoperative AKI. DESIGN Retrospective cohort study. SETTING Nanfang Hospital, Southern Medical University, China. PATIENTS Adult patients who had a serum creatinine and NT-proBNP measurement within 30 pre-operative days and at least one serum creatinine measurement within 7 days after noncardiac su...
Source: European Journal of Anaesthesiology - May 20, 2021 Category: Anesthesiology Tags: Perioperative risk management Source Type: research

Pre-operative anaemia and myocardial injury after noncardiac surgery: A retrospective study
BACKGROUND Pre-operative anaemia is associated with adverse outcomes of noncardiac surgery, but its association with myocardial injury after noncardiac surgery (MINS) has not been fully investigated. OBJECTIVE The association between pre-operative anaemia and MINS. DESIGN A single-centre retrospective cohort study. SETTING Tertiary care referral centre. PATIENTS Patients with measured cardiac troponin (cTn) I levels after noncardiac surgery. INTERVENTIONS Patients were separated according to pre-operative anaemia (haemoglobin (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 20, 2021 Category: Anesthesiology Tags: Perioperative risk management Source Type: research

The effects of preoperative moderate to severe anaemia on length of hospital stay: A propensity score-matched analysis in non-cardiac surgery patients
The objectives were to assess the frequency of moderate to severe anaemia and its association with length of hospital stay. DESIGN Post hoc analysis of the international observational prospective ‘Local ASsessment of VEntilatory management during General Anaesthesia for Surgery’ (LAS VEGAS) study. PATIENTS AND SETTING The current analysis included adult patients requiring general anaesthesia for non-cardiac surgery. Preoperative anaemia was defined as a haemoglobin concentration of 11 g dl−1 or lower, thus including moderate and severe anaemia according to World Health Organisation crite...
Source: European Journal of Anaesthesiology - May 20, 2021 Category: Anesthesiology Tags: Perioperative risk management Source Type: research

Expert consensus on peri-operative myocardial injury screening in noncardiac surgery
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - May 20, 2021 Category: Anesthesiology Tags: Invited commentary Source Type: research

Anesthesia for hepatico-pancreatic-biliary surgery and transplantation
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 17, 2021 Category: Anesthesiology Tags: Book review Source Type: research

Paraneoplastic pemphigus: A concern for anaesthetists in resource constrained settings
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 17, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Paradox of bispectral index and entropy during burst suppression
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 17, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Relative survival in adults with new delirium, cerebrovascular events or both after cardiac surgery: A prospective cohort study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 17, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Effect of preoperative subanaesthetic ketamine on postoperative pain in women undergoing modified radical mastectomy: A randomised control trial
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 17, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Low cholinesterase activity is a risk factor for delirium after cardiac surgery: A prospective cohort study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 17, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

General anaesthesia with desflurane or propofol in lung volume reduction surgery: Results of an unpublished randomised clinical trial
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 17, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Gaining insight in the peri-operative pain trajectory: A pilot study assessing feasibility of experience sampling method among patients undergoing ambulatory surgery
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 17, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Dose-dependent association between morphine requirement and mortality risk after resection for hepatocellular carcinoma
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 17, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

The synergistic effect of dexmedetomidine on propofol for paediatric deep sedation: A randomised trial
CONCLUSION The combination of dexmedetomidine and propofol for paediatric procedural sedation achieved a significant reduction in median propofol dose and a slightly shorter median time to discharge from PACU. Large-scale studies may determine whether this reduction decreases the risk of significant adverse events. TRIAL REGISTRATION ClinicalTrials.gov identifier NCT02952222 (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 17, 2021 Category: Anesthesiology Tags: Sedation Source Type: research

Dexmedetomidine versus midazolam for sedation during endobronchial ultrasound-guided transbronchial needle aspiration: A randomised controlled trial
CONCLUSION The use of DEX during EBUS-TBNA was not superior to MDZ in terms of oxygen desaturation. TRIAL REGISTRATION Clinicaltrials.gov identifier: NCT02157818. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 17, 2021 Category: Anesthesiology Tags: Sedation Source Type: research

Effect of dexmedetomidine on Nociception Level Index-guided remifentanil antinociception: A randomised controlled trial
CONCLUSION In ASA 1 and 2 patients receiving Nociception Level Index-guided antinociception, dexmedetomidine decreases intra-operative remifentanil requirements. Combined frontal electroencephalogram and Nociception Level Index monitoring can measure dexmedetomidine's hypnotic and opioid-sparing effects during remifentanil-propofol target-controlled infusion anaesthesia. TRIAL REGISTRATIONS Clinicaltrials.gov: NCT03912740, EudraCT: 2018-004512-22. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 17, 2021 Category: Anesthesiology Tags: Pain Source Type: research

Assessing the antinociceptive effect of nitrous oxide to tetanic stimulation in anaesthetised patients with new intra-operative nociception monitors: An observational study
CONCLUSION In anaesthetised patients, our study demonstrated clinically significant antinociceptive properties of N2O. Our results showed that low concentrations of N2O (25%) are as effective as higher concentrations (50%) to achieve a significant antinociceptive effect. These findings may help decrease negative effects of using higher concentrations of N2O, including its side effects and its environmental pollution. TRIAL REGISTRATION ClinicalTrials.gov registration identifier: NCT02701478. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 17, 2021 Category: Anesthesiology Tags: Pain Source Type: research

Persistent postoperative opioid use in Europe: A systematic review
CONCLUSION To describe persistent opioid use in relation to specific countries or types of surgery is not possible. Because of the wide ranges observed, we can neither confirm nor rule out a possible public health problem linked to the persistent use of opioids in Europe. STUDY REGISTRATION PROSPERO: CRD42019154292. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 17, 2021 Category: Anesthesiology Tags: Pain Source Type: research

Prolonged time to extubation after general anaesthesia is associated with early escalation of care: A retrospective observational study
CONCLUSION Prolonged time to extubation occurred in nearly 10% of cases and was associated with an increased incidence of escalation of care. Many independent factors associated with ‘prolonged extubation’ were nonmodifiable by anaesthetic management. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 17, 2021 Category: Anesthesiology Tags: Anaesthesia Source Type: research

New-onset intra-operative hyperthermia in a large surgical patient population: A retrospective observational study
CONCLUSION Mild intra-operative hyperthermia is not uncommon particularly in longer procedures and small children. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 17, 2021 Category: Anesthesiology Tags: Anaesthesia Source Type: research

Protective effect of sevoflurane on vascular endothelial glycocalyx in patients undergoing heart valve surgery: A randomised controlled trial
CONCLUSION Sevoflurane can decrease glycocalyx degradation in patients undergoing heart valve surgery under cardiopulmonary bypass. TRIAL REGISTRATION Chinese Clinical Trial Registry, chictr.org.cn, identifier: ChiCTR1800016367. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 17, 2021 Category: Anesthesiology Tags: Anaesthesia Source Type: research

Mode of blood pressure monitoring and morbidity after noncardiac surgery: A prospective multicentre observational cohort study
BACKGROUND Control of blood pressure remains a key goal of peri-operative care, because hypotension is associated with adverse outcomes after surgery. OBJECTIVES We explored whether increased vigilance afforded by intra-arterial blood pressure monitoring may be associated with less morbidity after surgery. DESIGN A prospective observational cohort study. SETTING Four UK secondary care hospitals. PATIENTS A total of 4342 patients ≥45 years who underwent noncardiac surgery. METHODS We compared outcome of patients who received peri-operative intra-arterial blood pressure monitoring ...
Source: European Journal of Anaesthesiology - April 17, 2021 Category: Anesthesiology Tags: Haemodynamics Source Type: research

The effect of moderate intraoperative blood loss and norepinephrine therapy on sublingual microcirculatory perfusion in patients having open radical prostatectomy: An observational study
BACKGROUND It is not clear whether moderate intraoperative blood loss and norepinephrine used to restore the macrocirculation impair the microcirculation and affect microcirculation/macrocirculation coherence. OBJECTIVE We sought to investigate the effect of moderate intraoperative blood loss and norepinephrine therapy administered to treat intraoperative hypotension on the sublingual microcirculation. DESIGN Prospective observational study. SETTING University Medical Center Hamburg-Eppendorf, Hamburg, Germany, from November 2018 to March 2019. PATIENTS Thirty patients scheduled for open rad...
Source: European Journal of Anaesthesiology - April 17, 2021 Category: Anesthesiology Tags: Haemodynamics Source Type: research

Prediction of fluid responsiveness using lung recruitment manoeuvre in paediatric patients receiving lung-protective ventilation: A prospective observational study
BACKGROUND Pressure-based dynamic variables are poor predictors of fluid responsiveness in children, and their predictability is expected to reduce further during lung-protective ventilation with a low tidal volume. OBJECTIVE We hypothesised that lung recruitment manoeuvre (LRM)-induced changes in dynamic variables improve their ability to predict fluid responsiveness in children. DESIGN Prospective observational study. SETTING Tertiary care children's hospital, single-centre study performed from June 2017 to May 2019. PATIENTS We included patients less than 7 years of age undergoing cardiac...
Source: European Journal of Anaesthesiology - April 17, 2021 Category: Anesthesiology Tags: Haemodynamics Source Type: research

Predicting fluid responsiveness: Does it answer the right question?
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - April 17, 2021 Category: Anesthesiology Tags: Editorial Source Type: research

Obstetric anesthesiology: an illustrated case-based approach
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 10, 2021 Category: Anesthesiology Tags: Book review Source Type: research

Thromboelastometry-based algorithm and transfusion management during orthotopic liver transplantations
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 10, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Outcome of asymptomatic patients with positive SARS-CoV-2 viral RNA reverse transcriptase-PCR undergoing surgery: A matched cohort study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 10, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

The ‘ephemeral’ intensive care units that saved the French healthcare system, a new concept to be preserved
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 10, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Sevoflurane sedation and nephrogenic diabetes insipidus in patients affected with severe acute respiratory syndrome coronavirus 2
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 10, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Effects of magnesium on the dose of rocuronium for deep neuromuscular blockade: A randomised controlled trial
CONCLUSION Magnesium reduced the dose of rocuronium required for deep neuromuscular blockade by approximately 20% without affecting the recovery time after administration of sugammadex. TRIAL REGISTRATION ClinicalTrials.gov identifier: NCT04013243. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 10, 2021 Category: Anesthesiology Tags: Neuromuscular blocking agents Source Type: research

Mini fluid chAllenge aNd End-expiratory occlusion test to assess flUid responsiVEness in the opeRating room (MANEUVER study): A multicentre cohort study
CONCLUSION In patients undergoing laparotomy the mini-FC reliably predicted fluid responsiveness with high-sensitivity and specificity. The EEOT showed poor discriminative value and cannot be recommended for assessment of fluid responsiveness in this surgical setting. TRIAL REGISTRATION NCT03808753. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - March 10, 2021 Category: Anesthesiology Tags: Haemodynamics Source Type: research

Effect of fluid resuscitation on cerebral integrity: A prospective randomised porcine study of haemorrhagic shock
BACKGROUND The treatment of haemorrhagic shock is a challenging task. Colloids have been regarded as standard treatment, but their safety and benefit have been the subject of controversial debates. Negative effects, including renal failure and increased mortality, have resulted in restrictions on their administration. The cerebral effects of different infusion regimens are largely unknown. OBJECTIVES The current study investigated the impact of gelatine-polysuccinate, hydroxyethyl starch (HES) and balanced electrolyte solution (BES) on cerebral integrity, focusing on cerebral inflammation, apoptosis and blood fl...
Source: European Journal of Anaesthesiology - March 10, 2021 Category: Anesthesiology Tags: Haemodynamics Source Type: research