A stitch in time saves early spinal anaesthesia-induced hypotension
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - October 14, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Efficacy of intra-operative administration of iron isomaltoside for preventing postoperative anaemia after total knee arthroplasty
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - October 14, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Antinociceptive effect of nitrous oxide
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - October 14, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Comments on ‘U-shaped relationship between preoperative plasma fibrinogen levels and severe peri-operative bleeding in cardiac surgery: A report from the Perioperative Events aSSessment in Adult Cardiac surgery (PESSAC) registry’ by Mion et al.
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - October 14, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

High-fidelity hybrid simulation for emergency cricothyroidotomy using a three-dimensional printed larynx and a simulated patient
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - October 14, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

The long and short of it: Nonstandardised length of nasopharyngeal airways
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - October 14, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Impact of endotracheal tube taping site on tube displacement during head movements: A prospective randomised controlled study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - October 14, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Ultrasonographic measurement of tongue thickness to predict upper airway obstruction after palatoplasty: A preliminary cohort study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - October 14, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

The C-E versus modified V-E hand positions for holding a face mask when ventilating an edentulous patient: A randomised crossover trial
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - October 14, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Videolaryngoscopy vs. Direct Laryngoscopy for Elective Airway Management in Paediatric Anaesthesia: A prospective randomised controlled trial
BACKGROUND The indirect visualisation of the glottic area with a videolaryngoscope could improve intubation conditions which may possibly lead to a higher success rate of the first intubation attempt. OBJECTIVE Comparison of videolaryngoscopy and direct laryngoscopy for elective airway management in paediatric patients. DESIGN Prospective randomised controlled trial. SETTINGS Operating room. PARTICIPANTS 535 paediatric patients undergoing elective anaesthesia with tracheal intubation. 501 patients were included in the final analysis. INTERVENTIONS Patients were randomly allocated to t...
Source: European Journal of Anaesthesiology - October 14, 2021 Category: Anesthesiology Tags: Airway Source Type: research

For nasotracheal intubation, which nostril results in less epistaxis: right or left?: A systematic review and meta-analysis
CONCLUSION On the basis of the current available evidence, when both nostrils are patent, the right nostril is more appropriate for nasotracheal intubation, with a lower incidence and severity of epistaxis and faster intubation time. TRIAL REGISTRATION The study protocol has been registered in PROSPERO (CRD42020169949). (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - October 14, 2021 Category: Anesthesiology Tags: Airway Source Type: research

The impact of bolus versus continuous infusion of intravenous ketamine on bispectral index variations and desflurane administration during major surgery: The KETABIS study
The objective of this study was to compare the impact of intravenous ketamine (given either as a continuous infusion or as a bolus) on BIS and to compare desflurane administration and postoperative outcomes between the groups. DESIGN Prospective, randomised, parallel-group, open-label study. SETTING University hospital, operating room. PARTICIPANTS Fifty patients, scheduled for major abdominal surgery. INTERVENTIONS AND MAIN OUTCOMES MEASURES Patients were randomised into two groups: ketamine by intravenous continuous infusion – group (KI) and ketamine by i.v. bolus – group (KB). In ...
Source: European Journal of Anaesthesiology - October 14, 2021 Category: Anesthesiology Tags: Anaesthesia Source Type: research

Clinical reasoning in anaphylactic shock: addressing the challenges faced by anaesthesiologists in real time: A clinical review and management algorithms
Acute hypersensitivity reactions to drugs occur infrequently during anaesthesia and the peri-operative period. When clinical presentation includes the classical triad, erythema, cardiovascular abnormalities and increased airway pressure, the diagnosis is evident and the challenge is to prescribe a therapeutic regimen according to guidelines and to manage refractory signs in a timely manner. In many situations, however, the initial clinical signs are isolated, such as increased airway pressure or arterial hypotension. Rendering a differential diagnosis with causes and mechanisms other than acute hypersensitivity reactions (...
Source: European Journal of Anaesthesiology - October 14, 2021 Category: Anesthesiology Tags: Anaesthesia Source Type: research

Hypercapnia versus normocapnia for emergence from desflurane anaesthesia: Single-blinded randomised controlled study
BACKGROUND Rapid emergence from general anaesthesia is desirable only if safety is not sacrificed. Mechanical hyperventilation during hypercapnia produced by carbon dioxide infusion into the inspired gas mixture or by rebreathing was reported to shorten emergence time from inhalation anaesthesia. OBJECTIVES To test the hypothesis that hypercapnia produced by hypoventilation before desflurane cessation shortens emergence time from general anaesthesia (primary hypothesis) and reduces undesirable cardiorespiratory events. DESIGN A single-blinded randomised controlled study. SETTING A single university...
Source: European Journal of Anaesthesiology - October 14, 2021 Category: Anesthesiology Tags: Anaesthesia Source Type: research

Swallowing ability and intra-oral water-retaining ability during moderate propofol sedation in healthy human volunteers: A prospective observational study
BACKGROUND The cough reflex or aspiration under monitored anaesthesia care might be associated with sedative-induced changes in swallowing and intra-oral water-retaining abilities. OBJECTIVES To investigate the effects of moderate propofol sedation on swallowing and intra-oral water-retaining ability. DESIGN Prospective observational study. SETTING Single tertiary care centre during 2017. PARTICIPANTS A total of 13 healthy adult volunteers. INTERVENTION Volunteers in the supine position were asked to retain 10 ml of orally injected water for 5 min. After 5 minutes or when the wate...
Source: European Journal of Anaesthesiology - October 14, 2021 Category: Anesthesiology Tags: Anaesthesia Source Type: research

Oral melatonin as part of multimodal anxiolysis decreases emergence delirium in children whereas midazolam does not: A randomised, double-blind, placebo-controlled study
CONCLUSIONS A multimodal anxiolytic approach including oral melatonin, as opposed to oral midazolam, significantly reduced emergence delirium after sevoflurane anaesthesia. TRIAL REGISTRATION CTRI/2019/06/019850 in Clinical Trial Registry of India (www.ctri.nic.in) (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - October 14, 2021 Category: Anesthesiology Tags: Pediatrics Source Type: research

Effect of intra-operative high inspired fraction of oxygen on postoperative nausea and vomiting in children undergoing surgery: A prospective randomised double-blind study
BACKGROUND Administration of high inspired fraction of oxygen (FiO2) during anaesthesia has been proposed to decrease postoperative nausea and vomiting (PONV) in adults but has not been extensively studied in children. OBJECTIVES The primary objective of this study was to evaluate the effect of 80% FiO2 on the incidence of PONV in children undergoing surgery. DESIGN Prospective, randomised, study. SETTING Single-centre, teaching hospital. PATIENTS Children of either gender in the age group of 5 to 15 years scheduled for elective surgeries were assessed for eligibility. Emergency surgeries;...
Source: European Journal of Anaesthesiology - October 14, 2021 Category: Anesthesiology Tags: Pediatrics Source Type: research

Dexmedetomidine vs. total intravenous anaesthesia in paediatric emergence delirium: A network meta-analysis
CONCLUSION Clinical judgement, considering the patient's risk factors for the development of clinically significant outcomes such as emergence delirium and PONV, should be used when choosing between TIVA and sevoflurane with adjuvant dexmedetomidine. These findings are limited by the low quality of evidence (conditional recommendation). (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - October 14, 2021 Category: Anesthesiology Tags: Pediatrics Source Type: research

Neonatal tracheal intubation: From art to evidence
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - October 14, 2021 Category: Anesthesiology Tags: Editorial Source Type: research

Let's train CPR together: mandatory cardiopulmonary resuscitation competencies for undergraduate students in healthcare and education: A step forward to train schoolteachers
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 16, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Low oxygen saturation measured by pulse oximetry with a novel haemoglobin variant, Haemoglobin PKU: A case report
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 16, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Out-of-hospital cardiac arrest: comparing organised groups to individual first responders: A qualitative focus group study
CONCLUSION Team spirit and peer-support engages group first responders, whereas individual first responders are impaired by lack of social support. Involvement with society triggers both first responder types to become and stay first responders. As first responders in groups have substantial additional benefits, enhancing such groups might strengthen current first responder systems. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 16, 2021 Category: Anesthesiology Tags: Resuscitation Source Type: research

Effect of intravenous dexmedetomidine and remifentanil on neonatal outcomes after caesarean section under general anaesthesia: A systematic review and meta-analysis
BACKGROUND Various strategies have been used to mitigate haemodynamic instability during general anaesthesia for caesarean section. However, the safety of these strategies for neonates remains controversial. OBJECTIVE To investigate the effects of intravenous dexmedetomidine and remifentanil on neonatal outcomes during caesarean section under general anaesthesia. DESIGN Systematic review and meta-analysis of randomised controlled trials. DATA SOURCES Databases of PubMed, EMBASE and CENTRAL were searched until March 2020 and updated in February 2021. ELIGIBILITY CRITERIA Randomised controlled...
Source: European Journal of Anaesthesiology - September 16, 2021 Category: Anesthesiology Tags: Obstetrics Source Type: research

A randomised double-blind comparison of phenylephrine and norepinephrine for the management of postspinal hypotension in pre-eclamptic patients undergoing caesarean section
BACKGROUND Studies comparing phenylephrine and norepinephrine for the treatment of postspinal hypotension in pre-eclamptic patients are limited. OBJECTIVE To compare bolus doses of phenylephrine and norepinephrine for treating hypotension in pre-eclamptic mothers undergoing caesarean section under spinal anaesthesia. It was hypothesised that norepinephrine and phenylephrine use would be associated with similar neonatal outcome. DESIGN Randomised controlled study. SETTING Single centre, tertiary care, university teaching hospital, from December 2018 to March 2020. PATIENTS A total of 86 women...
Source: European Journal of Anaesthesiology - September 16, 2021 Category: Anesthesiology Tags: Obstetrics Source Type: research

Treatment of spinal anaesthesia-induced hypotension with cafedrine/theodrenaline versus ephedrine during caesarean section: Results from HYPOTENS, a national, multicentre, prospective, noninterventional study
This study relates to the cohort of patients receiving spinal anaesthesia for caesarean section. SETTING German hospitals using either C/T or ephedrine in their routine clinical practice. PATIENTS Women aged at least 18 years receiving spinal anaesthesia for caesarean section. INTERVENTIONS Bolus administration of C/T or ephedrine at the discretion of the attending anaesthesiologist. MAIN OUTCOME MEASURES Endpoints within 15 min after initial administration of C/T or ephedrine were area under the curve between the observed SBP and the minimum target SBP; and incidence of newly occurring heart ...
Source: European Journal of Anaesthesiology - September 16, 2021 Category: Anesthesiology Tags: Obstetrics Source Type: research

Factors associated with an increased risk of instrumental vaginal delivery in women with epidural analgesia for labour: A retrospective cohort study
BACKGROUND Epidural analgesia is the most effective form of labour analgesia, but is associated with an increased risk of instrumental delivery. OBJECTIVE To evaluate factors that are associated with an increased risk of instrumental delivery. DESIGN Retrospective cohort data study. SETTING Singapore's major public maternity institution. PATIENTS All obstetric patients who received labour epidural analgesia for vaginal delivery between January 2012 to December 2015. INTERVENTION None. MAIN OUTCOME MEASURES Our primary outcome was the incidence of instrumental delivery. RESUL...
Source: European Journal of Anaesthesiology - September 16, 2021 Category: Anesthesiology Tags: Obstetrics Source Type: research

The efficacy of high flow nasal oxygenation for maintaining maternal oxygenation during rapid sequence induction in pregnancy: A prospective randomised clinical trial
BACKGROUND High-flow nasal oxygenation (HFNO) for pre-oxygenation in rapid sequence induction (RSI) has only been assessed in volunteer parturients without intubation. OBJECTIVES To evaluate the efficacy of HFNO in comparison with the conventional facemask for oxygenation during RSI for caesarean section under general anaesthesia. SETTING Operating room in a tertiary hospital. DESIGN Prospective randomised, controlled study. PARTICIPANTS Thirty-four healthy parturients undergoing general anaesthesia for caesarean section. INTERVENTIONS Parturients were randomly assigned to HFNO or sta...
Source: European Journal of Anaesthesiology - September 16, 2021 Category: Anesthesiology Tags: Obstetrics Source Type: research

Intra-operative open-lung ventilatory strategy reduces postoperative complications after laparoscopic colorectal cancer resection: A randomised controlled trial
BACKGROUND The role of the positive end-expiratory pressure (PEEP) and lung recruitment manoeuvre (LRM) combination (termed open-lung strategy, OLS) during intra-operative mechanical ventilation is not clear. OBJECTIVE To determine whether an open-lung strategy constituting medium PEEP (6–8 cmH2O) and repeated LRMs protects against postoperative complications in at-risk patients undergoing laparoscopic colorectal cancer resection under low-tidal-volume ventilation. DESIGN A prospective, assessor-blinded, randomised controlled trial. SETTING Single university-affiliated hospital, conducted f...
Source: European Journal of Anaesthesiology - September 16, 2021 Category: Anesthesiology Tags: Ventilation Source Type: research

Sex difference and intra-operative tidal volume: Insights from the LAS VEGAS study
BACKGROUND One key element of lung-protective ventilation is the use of a low tidal volume (VT). A sex difference in use of low tidal volume ventilation (LTVV) has been described in critically ill ICU patients. OBJECTIVES The aim of this study was to determine whether a sex difference in use of LTVV also exists in operating room patients, and if present what factors drive this difference. DESIGN, PATIENTS AND SETTING This is a posthoc analysis of LAS VEGAS, a 1-week worldwide observational study in adults requiring intra-operative ventilation during general anaesthesia for surgery in 146 hospitals in 29 c...
Source: European Journal of Anaesthesiology - September 16, 2021 Category: Anesthesiology Tags: Ventilation Source Type: research

Effects of positive end-expiratory pressure/recruitment manoeuvres compared with zero end-expiratory pressure on atelectasis in children: A randomised clinical trial
CONCLUSIONS The reduced atelectasis provided by lung-protective ventilation does not persist from 15 min after extubation onwards. Further studies are needed to determine if it yields better results in other types of surgery. TRIAL REGISTRATION Chictr.org.cn (ChiCTR2000033469). (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 16, 2021 Category: Anesthesiology Tags: Ventilation Source Type: research

Optimal positive end-expiratory pressure to prevent anaesthesia-induced atelectasis in infants: A prospective, randomised, double-blind trial
CONCLUSION To reduce anaesthesia-induced atelectasis measured by ultrasound in healthy infants undergoing low abdominal, genitourinary or superficial regional operations, 6 cmH2O of PEEP was more effective than 3 cmH2O. PEEP of 9 cmH2O was comparable with 6 cmH2O. TRIAL REGISTRATION ClinicalTrials.gov identifier NCT03969173 (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 16, 2021 Category: Anesthesiology Tags: Ventilation Source Type: research

Effect of positive end-expiratory pressure during anaesthesia induction on non-hypoxic apnoea time in infants: A randomised controlled trial
CONCLUSION Positive end-expiratory pressure during anaesthesia induction with face mask ventilation increased nonhypoxic apnoea time in infants. CLINICAL TRIAL REGISTRATION www.clinicaltrials.gov, NCT03540940. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 16, 2021 Category: Anesthesiology Tags: Ventilation Source Type: research

Communication in the ICU during the COVID-19 pandemic
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - September 16, 2021 Category: Anesthesiology Tags: Editorial Source Type: research

More notable names in anaesthesia
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 12, 2021 Category: Anesthesiology Tags: Book review Source Type: research

Kidney dysfunction has a major impact on the effect of idarucizumab for dabigatran reversal
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 12, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Short-term administration of nonsteroidal anti-inflammatory drugs in older patients with hip fracture: A cohort study
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 12, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Tapentadol versus oxycodone analgesia and side effects after laparoscopic hysterectomy: A randomised controlled trial
CONCLUSION We found tapentadol to be similar in analgesic efficacy to oxycodone during the first 24 h after hysterectomy, but with significantly less nausea. TRIAL REGISTRATION ClinicalTrials.gov, NCT03314792. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 12, 2021 Category: Anesthesiology Tags: Pain Source Type: research

Pain management after complex spine surgery: A systematic review and procedure-specific postoperative pain management recommendations
CONCLUSIONS The analgesic regimen for complex spine surgery should include pre-operative or intra-operative paracetamol and COX-2 specific inhibitors or NSAIDs, continued postoperatively with opioids used as rescue analgesics. Other recommendations are intra-operative ketamine and epidural analgesia using local anaesthetics with or without opioids. Although there is procedure-specific evidence in favour of intra-operative methadone, it is not recommended as it was compared with shorter-acting opioids and due to its limited safety profile. Furthermore, the methadone studies did not use non-opioid analgesics, which shoul...
Source: European Journal of Anaesthesiology - August 12, 2021 Category: Anesthesiology Tags: Pain Source Type: research

Effects of pupillary reflex dilation-guided opioid administration on remifentanil and morphine consumption during laparoscopic surgery: A randomised controlled trial
BACKGROUND Analysis of pupillary reflex dilation (PRD) assesses the balance of nociception--antinociception. Laparoscopic surgery induces haemodynamic variations that are misleading. During laparoscopy, PRD guidance helps differentiate haemodynamic changes because of excess nociception from secondary changes related to the reflex release of endocrine factors. OBJECTIVE The present study evaluated the effect of PRD-guided antinociception on the administration of intra-operative remifentanil and immediate postoperative morphine consumption in patients undergoing elective laparoscopic surgery. DESIGN The stu...
Source: European Journal of Anaesthesiology - August 12, 2021 Category: Anesthesiology Tags: Pain Source Type: research

Prolonged postoperative cerebral oxygen desaturation after cardiac surgery: A prospective observational study
BACKGROUND Near-infrared spectroscopy (NIRS) is used routinely to monitor cerebral tissue oxygen saturation (SctO2) during cardiopulmonary bypass (CPB) but is rarely employed outside the operating room. Previous studies indicate that patients are at risk of postoperative cerebral oxygen desaturation after cardiac surgery. OBJECTIVES We aimed to assess perioperative and postoperative changes in NIRS-derived SctO2 in cardiac surgery patients. DESIGN Prospective observational study. SETTING The study was conducted in a tertiary referral university hospital in Australia from December 2017 to December 2...
Source: European Journal of Anaesthesiology - August 12, 2021 Category: Anesthesiology Tags: Perioperative medicine Source Type: research

Comparison of the ‘4-item assessment test’ and ‘nursing delirium screening scale’ delirium screening tools on non-intensive care unit wards: A prospective mixed-method approach
CONCLUSION The observational NuDESC showed a higher completion rate than the bedside 4AT, although overall testing rates were low. The necessary time needed to conduct the screening, the negative reactions by patients, insufficient team communication and a lack of initiation of any therapy were identified as major barriers in the implementation of the guideline-compliant screening protocol. For all staff, further education and awareness of the importance of POD diagnosis and treatment might improve the screening rates. The NuDesc received better results concerning acceptance, practicability and introduction into daily ...
Source: European Journal of Anaesthesiology - August 12, 2021 Category: Anesthesiology Tags: Perioperative medicine Source Type: research

Physostigmine for prevention of postoperative delirium and long-term cognitive dysfunction in liver surgery: A double-blinded randomised controlled trial
CONCLUSION Physostigmine had no effect on POD and POCD when applied after induction of anaesthesia up to 24 h. TRIAL REGISTRATION DOI 10.1186/ISRCTN18978802, EudraCT 2008-007237-47, Ethics approval ZS EK 11 618/08 (15 January 2009). (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 12, 2021 Category: Anesthesiology Tags: Perioperative medicine Source Type: research

Perioperative ADministration of Dexamethasone And blood Glucose concentrations in patients undergoing elective non-cardiac surgery – the randomised controlled PADDAG trial
CONCLUSION Dexamethasone 4 mg or 8 mg did not induce greater hyperglycaemia compared with placebo for nondiabetic and well controlled diabetic patients. Maximal peri-operative blood glucose concentrations in patients with diabetes were related to baseline HbA1c values in a concentration-dependent fashion after 8 mg of dexamethasone. TRIAL REGISTRATION Australia and New Zealand Clinical Trials Registry (ACTRN12614001145695): URL: https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=367272. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 12, 2021 Category: Anesthesiology Tags: Perioperative medicine Source Type: research

Does a balanced colloid decrease perioperative blood loss in paediatric cardiac surgery: A double-blinded randomized controlled trial?
CONCLUSION The use of a balanced colloid for peri-operative fluid therapy compared with a saline one is not associated with decreased blood loss or exposure to blood products. TRIAL REGISTRATION EudraCT identifier: 2012-006034-17 and ClinicalTrial.gov identifier: NCT02584868. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 12, 2021 Category: Anesthesiology Tags: Haemostasis-transfusion Source Type: research

Bleeding and antithrombotic therapy during pregnancy in women with poor aPL-related obstetric outcomes: A survey of 1075 cases from EUROAPS registry: ∗
CONCLUSIONS LDA and medium to high prophylactic LMWH during pregnancy in women with full-blown OAPS/noncriteria OAPS are safe. A slight increase in bleeding risk was noted in instrumental deliveries. No women who underwent spinal or epidural anaesthesia suffered bleeding complications. No haemorrhage was observed in cases where HCQ was added to standard therapy. (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 12, 2021 Category: Anesthesiology Tags: Haemostasis-transfusion Source Type: research

Prophylactic fibrinogen concentrate administration in surgical correction of paediatric craniosynostosis: A double-blind placebo-controlled trial
BACKGROUND Surgical craniosynostosis repair in children is associated with massive blood loss and significant transfusion of blood products. Fibrinogen concentrate is claimed to be useful in reducing blood loss and transfusion requirements. OBJECTIVE We investigated whether prophylactic administration of fibrinogen concentrate will reduce blood loss and transfusion requirements during paediatric craniofacial surgery. DESIGN Randomised, placebo-controlled, double-blind clinical trial. SETTING University medical centre. PATIENTS A total of 114 infants and children up to 25 months of age (media...
Source: European Journal of Anaesthesiology - August 12, 2021 Category: Anesthesiology Tags: Haemostasis-transfusion Source Type: research

Enhanced recovery after surgery: The road to improve peri-operative care globally
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - August 12, 2021 Category: Anesthesiology Tags: Editorial Source Type: research

Emergencies in anaesthesia
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 15, 2021 Category: Anesthesiology Tags: Book review Source Type: research

Severe acute coronary syndrome after carbetocin injection during caesarean delivery: a case report
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 15, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research

Postprocedure delirium and time point of assessment after electroconvulsive therapy: A prospective clinical service evaluation audit
No abstract available (Source: European Journal of Anaesthesiology)
Source: European Journal of Anaesthesiology - July 15, 2021 Category: Anesthesiology Tags: Correspondence Source Type: research