Preferential Protection of Cerebral Autoregulation and Reduction of Hippocampal Necrosis With Norepinephrine After Traumatic Brain Injury in Female Piglets: Retraction
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - July 1, 2022 Category: Pediatrics Tags: Online Retraction Source Type: research

Risk Factors for Sepsis-Associated Acute Kidney Injury in the PICU: A Retrospective Cohort Study
CONCLUSIONS: In children with severe sepsis, the degree of hemodynamic support as measured by the VIS and the presence of fluid overload may identify patients at increased risk of developing severe AKI. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - July 1, 2022 Category: Pediatrics Tags: Online Brief Reports Source Type: research

Multisystem Inflammatory Syndrome in Children and Acute Kidney Injury: Retrospective Study of Five Italian PICUs
CONCLUSIONS: In this multicenter Italian PICU experience, MIS-C is associated with AKI in one-in-five cases. In general, AKI is characterized by an associated reduction in glomerular filtration rate with a self-limiting time course. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - July 1, 2022 Category: Pediatrics Tags: Online Brief Reports Source Type: research

Association Between Continuous Kidney Replacement Therapy Clearance and Outcome in Pediatric Patients With Hyperammonemia Not Due to Inborn Error of Metabolism
CONCLUSIONS: In our single-center retrospective study, we failed to find an association between clearance on CKRT and improved survival nor decreased cerebral edema on head imaging. In fact, we failed to find an association between ammonia level and mortality, after controlling for illness severity. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - July 1, 2022 Category: Pediatrics Tags: Online Brief Reports Source Type: research

Inferior and Superior Vena Cava Saturation Monitoring After Neonatal Cardiac Surgery*
OBJECTIVES: Superior vena cava oxygen saturation (SVC O2) monitoring is well described for early detection of hemodynamic deterioration after neonatal cardiac surgery but inferior vena cava vein oxygen saturation (IVC O2) monitoring data are limited. DESIGN: Retrospective cohort study of 118 neonates with congenital heart disease (52 single ventricle) from February 2008 to January 2014. SETTING: Pediatric cardiac ICU. PATIENTS: Neonates ( (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - July 1, 2022 Category: Pediatrics Tags: Online Cardiac Intensive Care Source Type: research

Assessing the Impact of Nasotracheal Intubation on Postoperative Neonates With Congenital Heart Disease: A Quality Improvement Project at a Single Heart Center
OBJECTIVES: Nasotracheal intubation (NTI) is associated with fewer unplanned extubations and improved oral motor skills compared with orotracheal intubation (OTI). Our study aimed to implement a practice change from OTI to NTI for neonatal cardiac surgery and assess impact on postoperative outcomes. DESIGN: Single-center, prospective, quality improvement study. SETTING: Academic children’s hospital. PATIENTS: One hundred thirty neonates undergoing cardiac surgery with cardiopulmonary bypass. INTERVENTIONS: NTI during index cardiac surgery. MEASUREMENTS AND MAIN RESULTS: Data were co...
Source: Pediatric Critical Care Medicine - July 1, 2022 Category: Pediatrics Tags: Online Cardiac Intensive Care Source Type: research

Supraventricular Tachycardia in Infants With Congenital Diaphragmatic Hernia: Prevalence, Associations, and Outcomes
CONCLUSIONS: SVT can occur in neonates with CDH and frequently requires treatment. Odds of occurrence are increased with greater CDH disease severity, ECMO, and prostaglandin use. In unadjusted logistic regression analysis, SVT was associated with adverse hospital outcomes, underscoring the importance of recognition and management in this vulnerable population. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - July 1, 2022 Category: Pediatrics Tags: Online Cardiac Intensive Care Source Type: research

Assessment of Patient Health-Related Quality of Life and Functional Outcomes in Pediatric Acute Respiratory Distress Syndrome*
CONCLUSIONS: Children with ARDS are at risk for deterioration in HRQL and FSS that persists up to 9 months after ARDS. Almost half of children with ARDS experience a poor outcome including death or severe reduction in HRQL at day 28/ICU discharge. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - July 1, 2022 Category: Pediatrics Tags: Online Clinical Investigations Source Type: research

Suboptimal Beta-Lactam Therapy in Critically Ill Children: Risk Factors and Outcome*
CONCLUSIONS: Subtherapeutic β-lactam concentrations are common in critically ill children and correlate with renal function. eGFR equations may be helpful in identifying patients who may require higher dosing. Future studies should focus on the impact of subtherapeutic concentrations on clinical outcome. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - July 1, 2022 Category: Pediatrics Tags: Online Clinical Investigations Source Type: research

Searching High and Low: The Association of Superior and Inferior Vena Cava Saturations With Outcomes in Neonates After Cardiac Surgery*
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - July 1, 2022 Category: Pediatrics Tags: Editorials Source Type: research

Challenges Remain to Assess Post-ICU Morbidity and Identify Attributable Risk in Children With Pediatric Acute Respiratory Distress Syndrome*
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - July 1, 2022 Category: Pediatrics Tags: Editorials Source Type: research

Beta-Lactams in Critically Ill Children: Time to Step Up Our Game?*
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - July 1, 2022 Category: Pediatrics Tags: Editorials Source Type: research

Early Extubation Following Congenital Heart Surgery: Time to Move on*
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - July 1, 2022 Category: Pediatrics Tags: Editorials Source Type: research

Resuscitating Children With Sepsis and Impaired Perfusion With Maintenance Fluids: An Evolving Concept*
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - July 1, 2022 Category: Pediatrics Tags: Editorials Source Type: research

Ultrasound Technology: Providing “More” for Research and Clinical Care in Low-Resource Settings*
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - July 1, 2022 Category: Pediatrics Tags: Editorials Source Type: research